Harvard Medical Area
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Protocol #
Revised 6/27/2012
Harvard Medical Area (HMA) Standing Committee on Animals – “Established in 1907”
180 Longwood Avenue, Suite 113 Boston, MA 02115 Tel: 617-432-3192 Fax: 617-432-3169
http://www.hms.harvard.edu/orsp/
iacuc@hms.harvard.edu
H.
TRANSGENIC/KNOCKOUT ANIMALS
1. Will your study involve transgenic or knockout animals?
Yes____ No____
2. If “YES”, complete the following:
a.
Describe the phenotype:
b.
Describe any pain or distress associated with the phenotype expressed and your proposed
procedure(s) to avoid or alleviate pain:
c.
Identify who will check the animals and how often, if pain or distress is anticipated:
d.
Define the duration of survival after expression of the phenotype:
e.
Describe the criteria you will use to determine pain and distress in the animals and your plan
for monitoring the animals:
f.
The construction of transgenic animals must be approved by the Committee on Microbiological
Safety or Partners Healthcare Institutional Biosafety Committee (PIBC).
COMS or PIBC Registration Registration #
Contact the Biosafety Officer at 617-432-4727 (HMS/HSPH) or 617-964-8550 (NRB/HIM) or 617-525-7341 (BWH) for appropriate registration.
g.
If receiving animals from an outside source, identify the origin of the animals, or their COMS
Registration Number, if on another HMA protocol.
Origin:
COMS/PIBC #:
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