RNA:Structure, Function, Transcription, Translation Puzzle Activity 1. The process of transferring the genetic code from DNA to RNA is called transcription . 2. DNA is used as the pattern or template to make RNA. 3. RNA stands for ribonucleic acid. RNA and DNA are both nucleic acids RNA NUCELOTIDES 4. Ribose a. What type of molecule is it? sugar b. What shape does it form? ring c. How is ribose different from deoxyribose? one more oxygen 5. Phosphate group a. What does the phosphate bond to? (same as in DNA nucleotide) sugar molecule - ribose 6. Nitrogen Base a. What are the four nitrogen bases used to make RNA nucleotides? adenine, guanine, cytosine, uracil b. Which base from DNA is replaced by uracil? thymine c. Is uracil a purine or a pyrimidine? single ring - pyrimidine d. What base is uracil complementary to? adenine TRANSCRIPTION: the making of RNA from DNA 7. What happens first during transcription? DNA unwinds and separates 8. Are both DNA strands used as patterns to make RNA? No, only one Describe how the RNA strand is made. DNA unwinds and separates, RNA nucleotides in nucleus bond to one side of DNA, when gene is completed mRNA breaks off and leaves nucleus, DNA closes back up 9. 10. 11. What direction is the RNA strand made? 5’ -3’ Once the RNA strand is made it is released from the DNA and leaves the nucleus to go to other parts of the cell. 12. How does transcription differ from replication? Making RNA, not DNA 13. Is RNA single or double-stranded? single TYPES OF RNA 14. 15. What are the 3 types of RNA and their abbreviations? messenger RNA- mRNA, ribosomal RNA – rRNA transfer RNA-tRNA Complete the table. Type of RNA mRNA tRNA rRNA Shape Function Location Single Strand Carries code from DNA in nucleus to ribosome Nucleus -> ribosome Single strand folded in a T shape Globular Carries amino acids to ribosome in order to make protein Cytoplasm -> ribosome Combines with proteins to form ribosomes ribosomes mRNA AND THE GENETIC CODE 16. What controls the sequence of RNA bases? the DNA sequence 17. The RNA nucleotides are complimentary to the DNA nucleotides 18. What is a codon? 3 mRNA bases 19. What do the mRNA codons code for? amino acids 20. What polymer does a chain of amino acids make? protein 21. Which amino acids are specified by the RNA strand that you have assembled? cysteine, glutamic acid 22. What is the name of the process that makes RNA from DNA? Where in the cell does it occur? transcription; nucleus 23. Complete the table by using check marks to indicate to which molecule each characteristic applies. Some characteristics may be found in both molecules. Similarities and Differences Between DNA and RNA DNA RNA Deoxyribonucleic acid X Ribonucleic acid X Ribose present X Deoxyribose present X Phosphate group X X present Adenine present X X Thymine present X Uracil present X Guanine present X X Cytosine present X X Formed from X X nucleotides Double-stranded X Single-stranded X Remains in nucleus X Moves out of nucleus X Contains a chemical X X message or code