Cardiology – PHAS 310 Instructional Objectives Upon completion of this course, the student will be able to: 1. Describe the normal anatomy and physiology of the heart and circulatory system. 2. Explain normal heart sounds and correlate the events associated with the waves of the jugular and carotid pulses with the phases of the cardiac cycle. 3. Describe the pathophysiology of congestive heart failure. List the causes, clinical findings, EKG abnormalities, diagnostic workup and medical management. Differentiate between acute and chronic CHF. 4. Differentiate between left and right-sided failure and how pulmonary capillary wedge pressure and central venous pressure are used to evaluate myocardial function. 5. Explain the complications of untreated heart failure and its effect on renal and pulmonary function with regard to: a. BUN b. fluid and electrolyte balance c. acid base balance 6. Define systemic hypertension. Describe the etiology, contributing factors and complications of the disease as it affects various organ systems to include: a. cardiovascular b. neurological c. renal Describe the initial evaluation and step-wise approach to initiating treatment. 7. Define arteriosclerosis and list disorders associated with early arteriosclerosis. Describe etiologic factors in the development of the disease to include: a. hypercholesterolemia b. hypertriglyceridemia Discuss complications, prevention and treatment of the disease. 8. Describe the etiology, risk factors, clinical features and treatment associated with pulmonary hypertension and cor pulmonale. 9. Describe the Goodwin classification of myocardial disease (dilated, restrictive and hypertrophic cardiomyopathies) to include their pathophysiology, etiologies, diagnostic workup and treatment. 10. Describe the etiology, laboratory studies, clinical features, course, prognosis and treatment of valvular lesions of the heart to include: a. mitral stenosis/regurgitation b. aortic stenosis/regurgitation c. mitral valve prolapse Discuss complications of prosthetic valve replacement. 11. Define rheumatic fever and identify its etiology. List the Jones criteria and explain each clinical feature. Discuss the course, prognosis, treatment and prevention of the disease. 12. List the clinical classification, etiologies, cardinal manifestations and treatment of pericarditis. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. Define endocarditis. List the most common etiology, clinical manifestation, differential diagnosis and indication for emergency therapy and prophylaxis. For the following non-invasive cardiac examination methods that include roentgenography, echocardiography, radionucleotide tests, discuss the indications and techniques for: a. stress tests b. MUGA scans c. thallium scans d. dipyridamole thallium scans e. MRIs List the indications and diagnostic value for Holter monitoring and signal averaged EKG. Describe cardiac catheterization and list the indications, contraindications, diagnostic, therapeutic applications and complications of the procedure. List the classifications of shock based on etiology (i.e. cardiogenic, extracardiac obstructive, oligemic, and distributive shock). Discuss the hemodynamic profiles, clinical manifestations and specific management of each. List commonly used vasopressor agents used to treat shock. Discuss cardiovascular and hemodynamic changes in pregnancy, complications of maternal cardiac disease with pregnancy and their management. Describe the risk factors and etiology of coronary heart disease and myocardial infarction. Describe the clinical manifestations, differential diagnosis, laboratory findings, prognosis and management of coronary heart disease and myocardial infarction. Identify the major complications that may follow a myocardial infarction as well as the treatment and prognosis for each. List the indications, patient selection criteria, risk and efficacy of angioplasty and bypass surgery. Discuss cardiac rehabilitation and its role post-operatively and post-myocardial infarction. Describe the risks of surgery in the cardiac patient. Describe the preoperative investigations and optimization of the cardiac patient. Describe the indications and selection of a candidate for cardiac transplant. List early and late course complications of the procedure. Explain the electrical activity of the heart as recorded on an EKG tracing. Define the normal wave forms, duration and interval for each component of the tracing. Explain the vector concept and electrical axis of the normal EKG and significance of abnormalities of the axis. Measure atrial and ventricular rates. Identify rate, rhythm and conduction disturbances of the ventricle and atria to include: a. asystole b. atrial premature contractions (APCs) c. ventricular premature contractions (VPCs) d. heart blocks e. flutters f. fibrillations 29. 30. 31. 32. 33. g. bundle branch blocks h. hemiblocks Identify EKG manifestations of ventricular hypertrophy (left and right). List most common causes of each. Identify EKG findings associated with myocardial ischemia and infarction. Locate the infarct. Distinguish between an acute and old MI. Identify the EKG findings seen in digitalis toxicity and electrolyte disturbances. Discuss treatment of these arrhythmias or disturbances. Identify changes on an EKG associated with atrial enlargement. Explain Ppulmonale and P-mitrale. Describe the classification, etiology, clinical manifestations and treatment of the diseases of the aorta to include: a. aneurysms b. aortic dissection c. aortic occlusions d. aortitis