Supplementary Table 6 - Word file (84 KB )

advertisement
Table S6. Putative programmed cell death associated proteins in A. fumigatus.
Protein
DAD/OST2
Predicted function
Oligosaccharyltransferase
subunit
DOC
Putative nuclease
CAS/CSE
Nuclear export receptor
USP7/UBP21 Ubiquitin C-terminal hydrolase
Metacaspase
Apoptotic death effector,
controls morphology of PCD
ASF1/CIA1
Histone chaperone
ATP4
Mitochondrial ATPase subunit
DAP3
Mitochondrial ribosomal
protein
NDUFS1
Mitochondrial NADH
dehydrogenase subunit G
HEL10
High expression lethality
protein
PPA1
Vacuolar ATPase subunit
SAR1/SarA
Proteasomal degradation
STM1
Ribosome associated protein
VCP/p97/
AAA ATPase, regulation of
CDC48
ubiquitin-proteosome system
NSR1
Nucleolin, nucleolar
morphology
UTH1
Cell wall/mitochondrion
organization
PARP
Poly(ADP-ribose) polymerase,
caspase independent apoptosis
AMID
Apoptosis inducing factor,
caspase independent apoptosis
HrtA2/MORI
Nuclear serine protease
Bl-1
Bax inhibitor homolog
SRO7/SRO77
Tumor suppressor homolog,
NaCl-induced apoptosis
A.fumigatus
Afu1g03810
Reference(s)
Makishima et al., 20001
Afu8g06180
Hazan et al., 20012
Afu6g04010
Behrens et al., 20033
Afu5g01750 Vugmeyster et al., 20024
Afu3g14140
Madeo et al., 20025
Afu1g06700
Afu3g11030
Yamaki et al., 20016
Afu8g05440 Matsuyama et al., 19987
Afu7g04420
Berger et al., 20008
Afu5g04370
Ricci, 200416
Afu1g06580
Ligr et al., 20019
Afu2g15560
Ligr et al., 20019
Afu1g04940 Veldhuisen et al., 199710
Afu3g10920
Ligr et al., 20019
Afu2g17110
Madeo et al., 199911
Afu3g07710
Afu7g05450
Kondo and Inouye,
199212
Velours et al., 200213
Afu5g07320
Hong et al., 200414
Afu2g00230
Afu1g17180
Afu6g13650
Afu2g03220
Afu3g11040
Wu et al., 200215
Fahrenkrog et al, 200417
Chae et al, 200318
Wadskog et al, 200419
References:
1.
Makishima, T., Yoshimi, M., Komiyama, S., Hara, N. & Nishimoto, T. A subunit
of the mammalian oligosaccharyltransferase, DAD1, interacts with Mcl-1, one of
the bcl-2 protein family. J Biochem (Tokyo) 128, 399-405 (2000).
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Hazan, R., Sat, B., Reches, M. & Engelberg-Kulka, H. Postsegregational killing
mediated by the P1 phage "addiction module" phd-doc requires the Escherichia
coli programmed cell death system mazEF. J Bacteriol 183, 2046-50 (2001).
Behrens, P., Brinkmann, U. & Wellmann, A. CSE1L/CAS: its role in proliferation
and apoptosis. Apoptosis 8, 39-44 (2003).
Vugmeyster, Y. et al. The ubiquitin-proteasome pathway in thymocyte apoptosis:
caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP).
Mol Immunol 39, 431-41 (2002).
Madeo F, Fröhlich E, Fröhlich KU: A yeast mutant showing
diagnostic markers of early and late apoptosis. J Cell Biol 1997,
139:729-734.
Yamaki, M., Umehara, T., Chimura, T. & Horikoshi, M. Cell death with
predominant apoptotic features in Saccharomyces cerevisiae mediated by deletion
of the histone chaperone ASF1/CIA1. Genes Cells 6, 1043-54 (2001).
Matsuyama, S., Xu, Q., Velours, J. & Reed, J. C. The Mitochondrial F0F1ATPase proton pump is required for function of the proapoptotic protein Bax in
yeast and mammalian cells. Mol Cell 1, 327-36 (1998).
Berger, T. et al. The apoptosis mediator mDAP-3 is a novel member of a
conserved family of mitochondrial proteins. J Cell Sci 113 ( Pt 20), 3603-12
(2000).
Ligr, M. et al. The proteasomal substrate Stm1 participates in apoptosis-like cell
death in yeast. Mol Biol Cell 12, 2422-32 (2001).
Veldhuisen, G. et al. Isolation and analysis of functional homologues of the
secretion-related SAR1 gene of Saccharomyces cerevisiae from Aspergillus niger
and Trichoderma reesei. Mol Gen Genet 256, 446-55 (1997).
Madeo, F. et al. Oxygen stress: a regulator of apoptosis in yeast. J Cell Biol 145,
757-67 (1999).
Kondo, K. & Inouye, M. Yeast NSR1 protein that has structural similarity to
mammalian nucleolin is involved in pre-rRNA processing. J Biol Chem 267,
16252-8 (1992).
Velours, G., Boucheron, C., Manon, S. & Camougrand, N. Dual cell
wall/mitochondria localization of the 'SUN' family proteins. FEMS Microbiol Lett
207, 165-72 (2002).
Hong, S. J., Dawson, T. M. & Dawson, V. L. Nuclear and mitochondrial
conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol Sci 25,
259-64 (2004).
Wu, M., Xu, L. G., Li, X., Zhai, Z. & Shu, H. B. AMID, an apoptosis-inducing
factor-homologous mitochondrion-associated protein, induces caspaseindependent apoptosis. J Biol Chem 277, 25617-23 (2002).
Ricci JE, Munoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N,
Scheffler IE, Ellisman MH, Green DR. Disruption of mitochondrial function
during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I
of the electron transport chain. Cell. 2004 Jun 11;117(6):773-86.
Fahrenkrog B, Sauder U, Aebi U: The S. cerevisiae HtrA-like
protein Nma111p is a nuclear serine protease that mediates
yeast apoptosis. J Cell Sci 2004, 117:115-126
18.
19.
Chae HJ, Ke N, Kim HR, Chen S, Godzik A, Dickman M, Reed JC:
Evolutionarily conserved cytoprotection provided by Bax
Inhibitor-1 homologs from animals, plants, and yeast.
Gene 2003, 323:101-113.
Wadskog I, Maldener C, Proksch A, Madeo F, Adler L:
Yeast lacking the SRO7/SOP1-encoded tumor suppressor
homologue show increased susceptibility to apoptosis-like
cell death on exposure to NaCl stress. Mol Biol Cell 2004,
15:1436-1444.
Download