AS Science in Society 1.6 Reproductive choices This topic introduces the science of genetics and of some of the techniques that can be used to prevent the birth of babies with inherited conditions. It provides further practice in ethical decision making, in an individual context and in discussion of the framing of regulations. The references below to How Science Works (HSW) and to Science Explanations (SE) use the code letters found in sections 3.6 and 3.7 of the specification. Learning skills for Science (LSS) activities are integrated into all the AS topics. These represent an alternative or additional approach to some topics, emphasising the development of skills. They can be used flexibly for class or homework activities depending on time available. 1 2 3 4 5 6 7 8 9 10 11 12 Focus of session Inheritance of single gene disorders Personal implications and science (SE Ca, Cb, Cc, Cd, Cf) LSS skill area 5 Decision making on gene testing (HSW Hi, Hj, Hk) Multiple genes and interactions with the environment case control studies (SE Cc, Cd, Ce) Antenatal testing techniques, Down’s syndrome, false negatives (HSW Aa, Ag, Gf, Hb, Hi, Hj, Hk) Genes and chromosomes (SE Ca, Cb, Cc, Cd, Ce, Cf) Using ethical frameworks Genetic counselling - decision making (HSW Ha, Hh, Hi, Hj, Hk, Hl) Genetic counselling - decision making (HSW Ha, Hh, Hi, Hj, Hk, Hl) Advantages and disadvantages of screening of population at risk and whole population Reading skills ‘Develop and be able to express an informed personal point of view’ Review of the techniques of IVF and PGD and their uses. LSS skill area 3 Preparing arguments on sex selection Ethical principles (HSW Hh, Hi, Hj, Hk) Ethics Argument skills Review July 2011 Suggested activities Showing Gift DVD (Wellcome) Available from If DVD is not available use activities from unit 6 or 8 in Genes and You to raise some of the same issues LSS Skill area 5 LSS: Appropriate levels of communication – measuring the readability of text. Context: this is really context free, but the passages are about gene therapy. Follow up discussion on Gift DVD. See suggested activities on suggested homework Huntington’s disease activity Or textbook p80-83 Read and discuss text book p83-87 Antenatal testing activity Human karyotypes activity Using ethical frameworks activity Either homework or class activity Preparation for role play on Genetic counselling Textbook 89-91 Genetic counselling role play activity Genetic testing and screening comprehension Short activity to analyse a DNA fingerprint for paternity Designer babies activity Preparation for debate on sex selection from Wellcome Big Picture on Sex and Gender Debate on sex selection from Wellcome Big Picture on Sex and Gender Exam style question on cystic fibrosis Skill area 3 LSS: Making sense of text: representing it in your own way