SONOGRAPHIC MEASUREMENT OF NORMAL SPLEEN, LIVER AND KIDNEY IN HEALTHY PRIMARY SCHOOL PUPILS IN KAMPALA DISTRICT, UGANDA BY DR. OKELLO-OMARA RICHARD (M.B.Ch.B-MUK) [E-mail: richard_o_omara@yahoo.com] A DISSERTATION SUBMITTED IN PARTIAL FULFILMENT FOR THE AWARD OF DEGREE OF MASTER OF MEDICINE IN RADIOLOGY OF MAKERERE UNIVERSITY SUPERVISORS: 1. ASSOCIATE PROFESSOR ELSIE KIGULI-MALWADDE DEPARTMENT OF RADIOLOGY MAKERERE UNIVERSITY 2. ASSOCIATE PROFESSOR MICHAEL KAWOOYA DEPARTMENT OF RADIOLOGY MAKERERE UNIVERSITY © 2007 ABSTRACT Introduction The liver, spleen and kidneys are commonly affected by disease which may cause enlargement or reduction in size as well as other changes. Knowledge of the normal measurements of these organs is therefore very important in detecting alteration in the size of these organs that may be due to disease. Clinical assessment of their size is subjective with considerable interobserver and intraobserver errors. Ultrasound (US) scan is an established quick, non-invasive, inexpensive, widely available and reliable method for evaluation of liver, spleen and kidney sizes. The purpose of this study was to determine the normal range of ultrasound measurements for the spleen, liver and kidney in healthy primary school pupils aged 6 to 15 years in Kampala district, Uganda. Objectives The aim of the study was to determine the normal spleen, liver and kidney measurements by ultrasound, in healthy primary school pupils in Kampala district, Uganda. Methodology Two hundred and thirty eight randomly selected healthy pupils were studied. Their heights and weights were measured. They were then examined by abdominal ultrasound scan and their liver, spleen and kidney lengths as well as transverse diameters for kidneys and transverse widths for spleen were measured. The data was collected using well labelled data sheets. The data was entered into the computer using EPI-INFO and analysed by SPSS version 11 with the assistance of a statistician. The scatterplots were drawn using STATA programme, version 9. Study setting and design This was a cross-sectional study conducted in five universal primary education (UPE) schools in Kampala district Uganda, between June 2006 and November 2006. 1 Results A total of two hundred and thirty eight pupils were recruited and studied. The age range was 6 to 15 years. One hundred and twenty eight pupils were girls and one hundred and ten were boys. Only three pupils (all girls) were 15 years old. The lengths of the three organs showed the best correlation with age, height and body weight, with weight showing the greatest correlation of all except for the spleen where height showed the greatest correlation of all. The measurements compare favorably with those in previous studies. Conclusion Knowledge of the normal limits of the liver, spleen and kidneys in healthy children is important during sonographic measurement of their size. The study demonstrated that the lengths of the liver and kidneys showed the best correlation with body weight while that of the spleen showed the best correlation with height. The measurements of liver, spleen and kidney were not statistically different in boys and girls except for the spleen where the mean length was longer in boys than in girls who were 6-11 years of age. The lengths of these organs should be correlated with the body parameters, preferably weight or height where age is not known. The presented data may be used in daily routine sonography in the Ugandan population. 2