Human Anatomy and Physiology Laboratory The laboratory portion of Biology 202 is a very important aspect of the course. It is here that you will make the observations and identifications of structures discussed and relating to concepts covered in lecture. It is extremely important that you study each week for your weekly laboratory quizzes and that you stay current on your laboratory homework. The laboratory portion of your grade will amount to roughly a third of the points that are possible in the class. A portion of these points come from completion of the lab exercises which are due at the beginning of each lab from the previous week’s topic. They are intended to give you reinforcement of the structures that are studied each week and make the terms more familiar to you. The answers will be found in your lab manual and corresponding chapters from the textbook. The bulk of the points will come from weekly quizzes and the two lab practicals. The quizzes will be given at the beginning of each laboratory period (with the exception of the first lab period and the two lab periods when the practicals are given). Your lowest quiz score will be dropped from your grade prior to the calculation of your quiz percentage. If you miss a quiz (due to absence or tardy), you will receive a zero on that quiz. THERE WILL BE NO MAKE-UP QUIZZES. Please let me know if at any time you do not feel comfortable with some aspect of the class (specimens, cadaver, etc.). I understand that some religious and cultural beliefs may oppose some of the things which occur in class. However, at the same time, the things we do in class may continue on in your chosen career and may be unavoidable. I will try to do my best to accommodate you (within certain limits). Good luck and enjoy the semester. A final note: You will be required this semester and next to memorize a great number of unfamiliar terms. Your success will come only if you review these terms often. Studying five minutes before a quiz will not be enough—I guarantee you! Decide now that you will study with a study group and meet at least once a week. Week #1 Endocrine System Exercise 27; Ex. 28B Hypothalamus Releasing and inhibiting (tropic) hormones Pituitary Gland (hypophysis) Infundibulum Adenohypophysis ACTH TSH FSH LH GH PRL Neurohypophysis Oxytocin ADH Thyroid Gland Thyroxine Calcitonin Parathyroid glands PTH Pancreas Islets of Langerhans β cells: Insulin α cells: Glucagon Adrenal glands (suprarenal glands) Cortex Mineralcorticoids Glucocorticoids Medulla Epinephrine Norepinephrine Testes Testosterone Ovaries Estrogen Progesterone Pineal Gland melatonin Thymus Endocrine hormones, targets, and actions. Week #2 Blood Exercise 29A; Ex. 29B Erythrocytes Leukocytes Granulocytes Neutrophils Eosinophils Basophils Agranulocytes Lymphocytes Monocytes Platelets Hematological Tests Total WBC count Total RBC count Differential WBC count Hematocrit Hemoglobin concentration Coagulation time Hemostasis Vascular spasm Platelet plug Coagulation 1. Formation of prothrombin activator 2. Prothrombin → Thrombin 3. Fibrinogen → Fibrin Blood types A B AB O Rh factor Week #3 Anatomy of the Heart Exercise 30 Mediastinum Pericardium (parietal) Pericardial Cavity Epicardium (visceral pericardium) Myocardium Endocardium Interatrial Septum Interventricular Septum Apex of the Heart Superior Vena Cava Inferior Vena Cava Coronary Sinus Right Atrium Tricuspid Valve Right Ventricle Chordae Tendineae Papillary Muscles Pulmonary Semilunar Valve Pulmonary Trunk Right and Left Pulmonary Arteries Pulmonary Veins Left Atrium Bicuspid Valve (Mitral Valve) Left Ventricle Trabeculae Carneae Aortic Semilunar Valve Ascending Aorta Coronary Arteries Cardiac Veins Week #4 Cardiac System Physiology Exercise 31; Ex. 33A; Ex. 34B Electrocardiogram P wave QRS complex T wave Tachycardia Bradycardia Fibrillation Events in the Cardiac Cycle: see Figure 33A.1 pg. 492. Know what is happening during each of these events. Mid to late diastole: pressure in the heart is very low, blood is flowing passively from the pulmonary and systemic circulations into the atria and on through to the ventricles; 70-80% of ventricular filling occurs during this time; atrioventricular valves are open; semilunar valves are closed; near the end atrial contraction occurs and atrial pressure increases, forcing residual blood into the ventricles; ventricular filling is complete and EDV is reached; P wave occurs during this phase. Isovolumetric contraction: QRS complex occurs and ventricles contract; AV valves close, producing the first heart sound, but semilunar are not yet open. The ventricles are completely closed chambers. Pressure begins to climb in the ventricles. Ventricular Ejection: pressure inside ventricles is now greater than in the pulmonary trunk and aorta, so semilunar valves open and blood leaves the heart. Pressure is at its peak in the ventricles; aortic pressure reaches 120 mmHg; atria relax and blood begins to enter from superior and inferior vena cavae. Ventricles now reach ESV, all the blood that is going to leave the heart has left. Isovolumetric relaxation: T wave occurs and ventricles begin to relax. Pressure is greater in the pulmonary trunk and aorta so the semilunar valves close, producing the second heart sound; AV valves are still closed because pressure in atria is not great enough to open them; ventricles are again completely closed chambers. Early diastole: pressure in the atria from the return blood is now great enough to open the AV valves and blood begins to fill the ventricles. Week #5 Anatomy of Blood Vessels Exercise 32, 33B Arteries from the Arch of the Aorta 1. Brachiocephalic Artery 2. Left Common Carotid Artery 3. Left Subclavian Artery Arteries of the Neck and Head Common Carotid Arteries Internal Carotid Artery External Carotid Artery Arteries supplying blood to brain Vertebral arteries Basilar artery Internal carotid arteries Circle of Willis Arteries of the Upper Extremity Subclavian Artery Axillary Artery Brachial Artery Radial Artery Ulnar Artery Branches of the Abdominal Aorta Celiac Artery/Trunk Splenic Artery Left Gastric Artery Hepatic Artery Superior Mesenteric Artery Renal Arteries Gonadal Arteries Inferior Mesenteric Artery Common Iliac Artery Arteries of the Lower Extremities Internal Iliac Artery External Iliac artery Femoral Artery Popliteal Artery Anterior Tibial Artery Posterior Tibial Artery Veins of the Lower Extremity Posterior Tibial Vein Anterior Tibial Vein Popliteal Vein Femoral Vein Great Saphenous Vein External Iliac Vein Internal Iliac Vein Common Iliac Vein Veins of the Abdominal Region Gonadal Veins Renal Veins Hepatic Veins Hepatic Portal System Hepatic Portal Vein Superior Mesenteric Vein Splenic Vein Inferior Mesenteric Vein Left Gastric Vein Veins of the Upper Extremity Radial Vein Ulnar Vein Brachial Vein Basilic Vein Cephalic Vein Median Cubital Vein Axillary Vein Veins Draining the Head and Neck Subclavian Vein External Jugular Vein Internal Jugular Vein Brachiocephalic Vein Veins to the heart Superior/Inferior Vena Cava Week #6 Lymphatic System and Immune Response Exercise 35 Thoracic Duct Right Lymphatic Duct Cisterna Chyli Lymph Nodes (cervical, inguinal, axillary) Lymphoid Organs Spleen Thymus Tonsils Nonspecific Defense Physical/Chemical Barriers Neutrophils Monocytes Macrophages Inflammatory response Leukocyte extravasation Specific Defense Antigen presenting cells B cells – antibody mediated immunity T cells – cell-mediated immunity Antibody IgM IgG IgA IgE IgD Antigen Video handout notes Week #7: Lab Practical #1 Week #8 Respiratory System Exercise 36; Ex. 37A; 37B/ Paranasal Sinuses Maxillary Sinus Frontal Sinus Sphenoidal Sinus Ethmoidal Sinus Conducting Zone Structures Nostrils Nasal Cavity Nasal Septum Turbinate bones/conchae Meatuses Internal Nares Nasopharynx Pharyngeal Tonsils Oropharynx Uvula Palatine Tonsils Lingual Tonsils Laryngopharynx Larynx Thyroid Cartilage Epiglottis Glottis Vocal Cords (true and false) Trachea Bronchial Tree Primary Bronchi (main) Secondary Bronchi (lobar) Tertiary Bronchi (segmental) Bronchioles Terminal Bronchioles Respiratory Zone Structures Respiratory bronchioles Alveolar Ducts Alveoli Lungs Right Lung Superior, middle and Inferior Lobes Left Lung Superior and Inferior Lobe Cardiac notch Pleurae Visceral Pleura Parietal Pleura Pleural Cavity Mechanics of Breathing Diaphragm Intercostal Muscles Respiratory volumes Tidal volume Inspiratory reserve volume Expiratory reserve volume Vital capacity Residual volume Total lung volume Week # 9 Digestive System Exercise 38; Ex. 39A; Ex. 39B Serous Membranes Parietal Peritoneum Dorsal Mesentery Visceral Peritoneum Lesser Omentum Greater Omentum Mouth, Pharynx, and Associated Structures Oral (Buccal) cavity Hard palate Soft palate Rugae of the hard Palate Vestibule Uvula Decidous Teeth Permanent Teeth Incisors Canines Premolars Molars Tooth Crown Neck Root Alveoli Gingiva Enamel Dentin Cementum Tongue Taste Buds Frenulum Papillae Filiform Fungiform Circumvallate Salivary Glands Parotid Submandibular Sublingual Gastrointestinal Tract Esophagus Stomach Greater and Lesser Curvature Cardiac Orifice Gastroesophageal Sphincter Fundus Body Pylorus/Pyloric Sphincter Rugae Small Intestine Duodenum Jejunum Ileum/Ileocecal Valve Large Intestine Cecum Appendix Ascending colon Hepatic Flexure Transverse colon Splenic Flexure Descending Colon Sigmoid Colon Rectum/Anal Canal/Anus External/Internal Anal Sphincter Taenia Coli Epiploic Appendage Haustrum Accessory Digestive Organs Liver Right/Left Lobe Falciform ligament Gallbladder Pancreas Week #10 Urinary System Exercise 40 Kidney Hilum Renal Vessels Capsule Cortex Medulla Renal Pyramids Renal Columns Papilla Calyx ( calyces=pl.) Renal Pelvis Nephron Afferent Arteriole Glomerulus Efferent Arteriole Bowman’s Capsule Proximal Convoluted Tubule Loop of Henle Distal Convoluted Tubule Collecting Duct Ureter Urinary Bladder Trigone Urethra Urethral Orifice Internal Urethral Sphincter External Urethral Sphincter Week #11 Urinary system physiology Exercise 41A; Ex. 41B See handout Week # 12 Fluid and Electrolytes; Acid/Base Balances Exercise 47 Week #13 Reproductive System Exercise 42; Ex. 43 Scrotum Median Septum Dartos Muscle Cremaster Muscle Testes Seminiferous Tubules Epididymis Ductus (Vas) Deferens Inguinal Canal Spermatic Cord Ejaculatory Duct Seminal Vesicles Prostate Gland Bulbourethral Glands Urethra Spongy Urethra Penis Glans Prepuce Corpora Cavernosa Corpus Spongiosum Dorsal Vessels of the Penis Female Reproductive System Ovary Cortex Medulla Uterine Tubes Infundibulum Fimbriae Uterus Body Cervix Fundus Perimetrium Myometrium Endometrium Functionalis Layer/Menses Basalis Layer Vagina Rugae Fornix Vaginal Orifice Vestibular Glands Vulva Mons Pubis Labia Majora Perineum Labia Minora Clitoris Vestibule Mammary Glands Lactiferous Duct Nipple Areola Embryonic Development Exercise 44; Ex. 12 Zygote Morula Blastocyst Trophoblast Chorion Chorionic villi Amnion Yolk sac Allantois Fetal circulation Placenta Umbilical cord Umbilical vein Umbilical artery Ductus venosus Ligamentum venosum Inferior vena cava Foramen ovale Fossa ovalis Ductus arteriosus Ligamentum arteriosum Week #14: Lab Practical #2