Mendelien Genetics Study Guide—AP Biology Review Campbell Chapters 14 and 15 for this test. Vocabulary: true-breeding phenotype genotype homozygous heterozygous self-cross testcross hybrid cross chromosome duplication chromosome deletion chromosome inversion chromosome translocation dihybrid cross pleiotrophy epistasis multifactorial inheritance Concepts: Be familiar with Mendel’s experiments, his results for P1 and F1 crosses and conclusions he drew from them Law of segregation Law of independent assortment Be able to use the laws of probability/multiplication and additive rules (especially to solve complex problems)—Note: Read Section 14.2 in Campbell (pp. 258-259) Incomplete dominance—Concept understanding and ability to work these kinds of problems Codominance—Concept understanding and ability to recognize it in a problem Multiple alleles—Concept understanding and ability to work these kinds of problems Polygenic inheritance—Concept understanding, ability to recognize it in a problem and examples Function of SRY gene (Campbell Section 15.3 pp. 282-283) Sex-linked (X-linked) inheritance—Concept understanding and ability to work these kinds of problems Be familiar with the symptoms and the cause of the following genetic diseases: Cystic fibrosis Down syndrome Sickle cell anemia (Disease and trait) Klinefelter syndrome Huntington’s disease Turner syndrome Tay-Sachs disease phenylketonuria (PKU) hemophilia Duchenne muscular dystrophy Environmental impact on phenotype—(Campbell p.264) Be able to look at a pedigree chart and determine genotypes and/or probability of possible genotypes Gene linkage and crossing over Linkage maps The relationship between chromosome mapping and crossing over Barr body (Campbell p. 284) Polyploidy and how it occurs