CURRICULUM VITAE
1. Full name: Burov Sergey Vladimirovich
2. Date and place of Birth: August 10, 1955, St-Petersburg, Russia
3. Institutional affiliation: Senior Research Scientist, Head of Peptide and Polymer
microspheres synthesis Laboratory, Institute of Macromolecular Compounds of
Russian Academy of Sciences, St-Petersburg, Russia
4. Educational history:
1972-1977, student, Chemical department, St-Petersburg University, Russia
1977-1980, post-graduate student in bioorganic chemistry, Chemical department,
St-Petersburg University, Russia
1983 - Candidate of Chemical Sciences degree, Chemical department, St-Petersburg
University, Russia. Thesis: "Synthesis of biologically active LH-RH analogues".
Thesis
adviser - professor O.A. Kaurov.
5. Postdoctoral research training: - None
6. Professional experience:
1980-1987 Research Scientist, Chair of Natural Compounds, St-Petersburg
University,
Russia. 1987-1988 Research Scientist, Institute of Macromolecular Compounds of
Russian
Academy of Sciences, St-Petersburg, Russia. 1988-1989 Head of Peptide chemistry
Group,
Institute of Macromolecular Compounds RAS, St-Petersburg, Russia. 1989-1997
Senior
Research Scientist, Head of Peptide chemistry Group, Institute of Macromolecular
Compounds RAS, St-Petersburg, Russia. 1997-2004: Senior Research Scientist,
Head of Peptide
and Polymer microspheres synthesis Group, Institute of Macromolecular
Compounds RAS,
St-Petersburg, Russia. 2004-present Senior Research Scientist, Head of Peptide and
Polymer
microspheres synthesis Laboratory, Institute of Macromolecular Compounds RAS,
St-Petersburg,
Russia.
7. Honors and awards:
1983 St-Petersburg University award (the competition of scientific investigations of
Chemical Departments young scientists)
8. Selected publications:
1. The action of LH-releasing hormone and five analogues on oestradiol, oxytocin
and
vasopressin secretion by bovine granulosa cells in culture. Sirotkin A.V., Nitray
J.,
Nikolaiev S.V., Burov S.V. J. of Endocrinol., V. 136, P. 491-496, 1993.
2. Usage of RGD peptide for targeted nitric oxide delivery. V.S. Gurevich, D.
Lominadze,
A.S.O. Adeagbo, S.V. Burov, Y.G. Popov, F.N. Miller, D.A. Schuschke. Platelets,
1996,
V.7 N 1, P. 83-84.
3. Antitrombotic and vasorelaxant properties of a novel synthetic RGD peptide
containing
nitric oxide. V.S.Gurevich, D.G.Lominadze, A.S.O.Adeagbo, S.V.Burov,
Y.G.Popov,
M.V.Leko, F.K.Miller, D.A. Shuschke. Pharmacology, 1997, 55, P. 1-9.
4. The presence of autoantibodies to N-terminus domain of GluR1 subunit of AMPA
receptor in the blood serum of patients with epilepsy. S.A. Dambinova, G.A.
Izukenova,
S.V. Burov, E.V. Grigorenko, S.A. Gromov. J. Neurol. Sci. 1997, V.152, P. 93-97.
5. Analogs of dynorphin A (6-12) with N-methyl amino acids: biological activity and
structure
of side-products. S. Burov, G. Vlasov, M. Dorosh, Z. Schkarubskaya, V. Schkurov,
M. Muradymov, E. Wei. Peptides 1998, P. 810-811.
6. Synthesis of HCV and HIV B-cell epitopes using polystyrene supports with new
cross-linking agent. S. Burov, A. Menshikova, T. Evseeva, B. Shabsels, M. Leko, A.
Pavlotzkaya.
Peptides 2000, P. 201-202.
7. Ignatovich I.A., Dizhe E.B., Pavlotskaya A.V., Akifiev B.N., Burov S.V., Orlov
S.V., Perevozchikov A.P. Complexes of plasmid DNA with basic domain 47-57 of
the HIV-1 Tat protein are transferred to mammalian cells by endocytosis-mediated
pathways. J. Biol. Chem. 2003, V. 278, N 43, P. 42625-42636.
In total 105 articles.
9. Major research interest:
Synthesis and investigation of structure-activity relationship of biologically active
peptides (antitumour, anti-thrombotic and non-opiate analgesic activity). Study of peptides
application as carriers for pharmaceutical agents (directional transport to the target
cells), including gene delivery systems. Development of different types of
diagnostic systems (ELISA, latex test-systems). Investigations in the field of
peptide synthesis chemistry, preparation of polymer supports for SPPS and SPOS.
Study of peptide – polymer interaction and its influence on the process of molecular
recognition.