Name: ___________________________ Per. _____ WEBQUEST: HOW DNA WORKS AND DNA TECHNOLOGY PART I: HOW DNA WORKS A) Go to this website from the University of Utah’s Genetics Learning Center: http://gslc.genetics.utah.edu (DO NOT START WITH www.) B) At the Home Page: –click on “The Basics and Beyond” C) Click on “A Tour of the Basics”. Where it reads “You can also access the individual sections below”, click on each section listed below and answer the corresponding questions. Click “What Is DNA” 1) What does DNA stand for? 2) What is the shape of DNA? 3) What are the “sentences” of DNA called? 4) What do genes tell cells to do? 5) What do the following stand for? A T C G Click “What is a Gene?” 6) What directions do genes contain? Click “What is a Chromosome?” 7) How is DNA packaged into your cells? 8) What is a chromosome? 9) How many sets of chromosomes does a human have in each of their cells? 10) Which 2 sex chromosomes determine a male? 11) Which 2 sex chromosomes determine a female? 12) How many chromosomes in a mosquito? ____ an onion? _____ a carp? ___ Click “What Is Heredity?” 13) Explain why children do not look exactly like one of their parents. 14) How many chromosomes does each (human) parent contribute to their child? Click “What is Protein?” 15) In general, how does a protein function in a cell? 16) What role do proteins play in sending a pain signal? 17) Where do proteins come from? 18) Each gene in the DNA encodes what information? 19) What is the role of RNA in making proteins? 20) What part of the cell reads the RNA message? 21) Where does a protein travel to once it is made? PART II: Go back to the “Basics and Beyond” menu. Click on “Build a DNA Molecule”. In this section you will click and drag each nucleotide into position to practice correct pairing of DNA base pairs. 22) Draw the DNA Molecule you created in the space provided. PART III: Go back to the “Basics and Beyond” menu. Click on “Transcribe and Translate a Gene”. Read the information. Click to begin where it reads, “are you ready to transcribe a DNA sequence and translate it into a protein”. 23) What is the name of the process in which DNA unzips, and a messenger RNA is made? 24) What is the name of the process in which the mRNA sequence is read at the ribosome? 25) A protein is made by stringing what types of molecules together? 26) List the sequence of amino acids that resulted when you were done translating. PART IV: DNA TECHNOLOGY A) We are still using the website gslc.genetics.utah.edu B) At the Home Page Menu, Click on “Cloning in Focus.” Click on each of the following subheadings to answer the questions. Click “What is Cloning?” 1) Define Cloning 2) What types of clones are born naturally? 3) Who was Dolly? 4) Somatic cells are also called _____________________. 5) In order to clone a gene, a gene is inserted into a __________________________. 6) In order to create an embryo from a somatic cell, the donor egg cell smust have its ____________________ removed. 7) Play the animated feature (near the bottom of the screen) comparing natural reproduction to SCNT. Go back to the “Cloning in Focus Page Click “Click and Clone” 8) Give it a try! Go through the process of cloning a mouse! When you are done, do not click “Clone Mimi again!” until I see it was completed and I sign my initials here ________. 9) List all the materials needed to clone a mouse. 10) Place the following steps in the correct order from 1-6 _________Stimulate cell division _________deliver baby _________remove and discard nucleus from the egg cell _________isolate donor cells from egg donor and germ cell donor _________transfer the somatic cell nucleus into the egg cell _________implant embryo into surrogate mother Go back to the “Cloning in Focus Page Click “Why Clone?” 11) List 3 ways in which cloning is used for medical purpose. 12) List 3 other reasons that cloning might be done. 13) In your opinion, do you think that any of the reasons for cloning are justified? Explain. Go back to the “Cloning in Focus Page Click “Cloning Myths” 14) Explain 2 of the misconceptions about cloning. 1) 2) 15) What is nature vs. nurture? Go back to the “Cloning in Focus Page Click Is it Cloning? Or Not? 16) Take the Cloning Quiz. Write your score in the space here _________. Go back to the “Cloning in Focus Page Click What are the Risks of Cloning? 17) Explain the 4 risks of cloning. 1) 2) 3) 4)