List of omics@vib project topics For the current omics@VIB call, VIB provides 10 positions for integrative biology postdocs. Many VIB laboratories are suggesting an integrative biology topic for this program as indicated in the list below. You are free to select the topic of your own choice from the list and to design a 3 years postdoctoral project addressing this topic. More information on the laboratory of your choice as well as on the contact information is available through the links provided below. Please contact the group leader(s) in charge of this topic before submitting your final application. Cancer Cardiovascular Neurobiology Immunity/Infection/Inflammation Plant/Yeast research Bioinformatics/Proteomics Cancer Peter Carmeliet Lab Unbiased, genome wide-micro RNA profiling in endothelial cells to identify novel genetic candidates for anti-angiogenic therapy >>> See also 'Cardiovascular' e-mail Max Mazzone Lab PHD oxygen sensors and cancer: unraveling new hubs in the hypoxia response e-mail SWITCH Lab Mapping aggregation interactomes in human conformational diseases >>> See also 'Bioinformatics'/ 'Proteomics'; 'Neurobiology' e-mail / e-mail Frans Van Roy Lab Metazoan cadherin and catenin superfamilies: evolution from ancestral metazoan organisms to mammals, as addressed by bio-informatics, structural and functional analysis >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Chris Marine Lab An oncogenomics-based in-vivo screen to identify IncRNAs that modulate melanoma progression and metastasis >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Diether Lambrechts Lab Understanding hypoxia-driven changes in the tumor epigenome through an integrated epigenomic and proteomic approach >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Geert Berx Lab EMT-drawing a functional genome wide epigenetic landscape for coding and non-coding RNAs that drives malignant cancer progression. >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Jan Cools Lab Interpretation of leukemia genomes and transcriptomes through integrative regulatory genomics >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Cardiovascular Jody Haigh Lab Identification and functional characterization of non-coding RNAs involved in cardiovascular cell (de)differentiation e-mail Peter Carmeliet Lab Unbiased, genome wide-micro RNA profiling in endothelial cells to identify novel genetic candidates for anti-angiogenic therapy >>> See also 'Cancer' e-mail Neurobiology Emre Yaksi Lab Quantitative approaches to study the role of neuromodulation in brain circuits and animal behavior e-mail Wim Annaert Lab Subcellular proteomics/lipidomics as an integrative approach to identify novel targets in neurodegenerative diseases >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Bart De Strooper Lab Deep-sequencing and bioinformatics analysis of coding and non-coding RNAs in Alzheimer's Disease >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Bassem Hassan Lab Live quantitative decoding of the transcriptional control of neural identity through in vivo functional genomics. e-mail Albena Jordanova Lab Identification of neurodegenerative pathways triggered by mutations in aminoacyl-tTNA synthetases using functional genomics and transcriptomics approaches in Drosophila e-mail Claudia Bagni Lab Analysis of CYFIP1 transcriptomics: relevance to Autism, FXS and Schizofrenia e-mail Patrik Verstreken Lab Synaptic ubiquitome changes in Parkinson's disease e-mail SWITCH Lab Mapping aggregation interactomes in human conformational diseases >>> See also 'Bioinformatics'/ 'Proteomics'; 'Cancer' e-mail / e-mail Vincent Bonin Lab Combining computational, imaging and optogenetic approaches to investigate visual processing in the awake mouse brain e-mail Immunity/Infection/Inflammation Peter Vandenabeele Lab Global analysis of transcriptome and spliceosome during modulation of necroptosis sensitivity >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Rudi Beyaert Lab Dissecting inflammation and innate immunity through the 'omics' glass >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Jeroen Raes Lab Combining multi-omics to investigate host-microbiome interplay towards personalized medicine >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Stefan Magez Lab Immunomics of chronic infections: mapping a host-parasite immune interactome with the aim of designing a new approach to the currently failing strategies of anti-parasite vaccination e-mail Mo Lamkanfi Lab Exploring the specific Nlrp6 interactome and its role in immune signaling >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Adrian Liston Lab Functional validation of novel autoimmune genes found through genomic screening >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Claude Libert Lab State of the art bioinformatics at genome-wide level to identify, validate and model novel genetic factors that determine anti-inflammation therapy with glucocorticoids in several model systems >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Jan Steyaert Lab Next generation sequencing technologies applied to nanobody discovery: by-passing in vitro screening by phage display for direct in silico candidate selection >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Joris Messens Lab The interaction proteome of oxidative stress signaling in Mycobacterium tuberculosis >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Patrick Van Dijck Lab Protein-protein interactions, metabolic flux and methylation status: an integrated study of the role of the methionine biosynthetic pathway during host-pathogen interaction and biofilm formation in the human fungal pathogen Candida albicans >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Plant/Yeast Lieven De Veylder Lab Modeling endoreduplication in developing tissues of Arabidopsis thaliana e-mail Jenny Russinova Lab Deciphering the brassinosteroid signaling network in plants by the proteome e-mail Geert De Jaeger Lab Isolation of new cell growth regulators by mapping the protein interactome dynamics at G1 re-entry in Arabidopsis thaliana >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Frank Van Breusegem Lab Omics-assisted discovery of photorespiratory network components targeted by small molecules e-mail Steven Maere Lab A novel approach to probe crosstalk between plants stress response pathways under field conditions >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Mieke Van Lijsebettens Lab Identification of the molecular networks of chromatin modifying complexes to investigate their role in leaf growth and plasticity e-mail Alain Goossens Lab Genome-wide monitoring of changes in transcription factor binding and chromatin modification following jasmonate perception in the model plants Arabidopsis and Medicago e-mail Wout Boerjan Lab Genome-wide association genetics of the aromatic metabolome/lignome in Arabidopsis >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Johan Thevelein Lab Application of whole-genome complex trait analysis to elucidate a novel nutrient signaling pathway in yeast >>> See also 'Bioinformatics'/ 'Proteomics' e-mail Bioinformatics/Proteomics Lennart Martens Lab Building an inverse search engine: learning from integrated across-omics life sciences data which questions can be answered e-mail SWITCH Lab Mapping aggregation interactomes in human conformational diseases >>> See also 'Cancer'; 'Neurobiology' e-mail / e-mail Steven Maere Lab A novel approach to probe crosstalk between plants stress response pathways under field conditions >>> See also 'Plant/Yeast' e-mail Jeroen Raes Lab Combining multi-omics to investigate host-microbiome interplay towards personalized medicine >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Frans Van Roy Lab Metazoan cadherin and catenin superfamilies: evolution from ancestral metazoan organisms to mammals, as addressed by bio-informatics, structural and functional analysis >>> See also 'Cancer e-mail Adrian Liston Lab Functional validation of novel autoimmune genes found through genomic screening >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Claude Libert Lab State of the art bioinformatics at genome-wide level to identify, validate and model novel genetic factors that determine anti-inflammation therapy with glucocorticoids in several model systems >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Bart De Strooper Lab Deep-sequencing and bioinformatics analysis of coding and non-coding RNAs in Alzheimer's Disease >>> See also 'Neurobiology' e-mail Chris Marine Lab An oncogenomics-based in-vivo screen to identify IncRNAs that modulate melanoma progression and metastasis >>> See also 'Cancer' e-mail Diether Lambrechts Lab Understanding hypoxia-driven changes in the tumor epigenome through an integrated epigenomic and proteomic approach >>> See also 'Cancer' e-mail Geert Berx Lab EMT-drawing a functional genome wide epigenetic landscape for coding and non-coding RNAs that drives malignant cancer progression. >>> See also 'Cancer' e-mail Geert De Jaeger Lab Isolation of new cell growth regulators by mapping the protein interactome dynamics at G1 re-entry in Arabidopsis thaliana >>> See also 'Plant/Yeast' e-mail Jan Tavernier Lab Next-generation human interactome mapping: development and application of a high throughput micro-array MAPPIT technology platform e-mail Jan Steyaert Lab Next generation sequencing technologies applied to nanobody discovery: by-passing in vitro screening by phage display for direct in silico candidate selection >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Joris Messens Lab The interaction proteome of oxidative stress signaling in Mycobacterium tuberculosis >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Kevin Verstrepen Lab Hunting for unstable tandem repeats in the human genome: an overlooked source of missing heritability and cryptic diseases e-mail Kris Gevaert Lab In-depth analysis and functional validation of the substrates of the cytosolic metallo-caboxypeptidases using comtemporary degradomics e-mail Mo Lamkanfi Lab Exploring the specific Nlrp6 interactome and its role in immune signaling >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Nico Callewaert Lab Genome analysis-enabled directed evolution of the glycome of biopharmaceutical cell factories e-mail Patrick Van Dijck Lab Protein-protein interactions, metabolic flux and methylation status: an integrated study of the role of the methionine biosynthetic pathway during host-pathogen interaction and biofilm formation in the human fungal pathogen Candida albicans >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Peter Tompa Lab Comparative analysis of cellular regulatory and quality control mechanisms integrating functional, structural and interaction data on the ubiquitin-proteasome pathway e-mail Peter Vandenabeele Lab Global analysis of transcriptome and spliceosome during modulation of necroptosis sensitivity >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Rudi Beyaert Lab Dissecting inflammation and innate immunity through the 'omics' glass >>> See also 'Immunity'/ 'Infection' / 'Inflammation' e-mail Wim Annaert Lab Subcellular proteomics/lipidomics as an integrative approach to identify novel targets in neurodegenerative diseases >>> See also 'Neurobiology' e-mail Wout Boerjan Lab Genome-wide association genetics of the aromatic metabolome/lignome in Arabidopsis >>> See also 'Plant/Yeast' e-mail