MOLECULAR BIOLOGY AND BIOCHEMISTRY
MBB 442-3
Proteomics
Summer 2012
Instructor:
Dr. F. Pio, Office: SSB 6112
Description/topics:
Course Description:
The avalanche of genomics, proteomics, transcriptomics, clinical data… is
changing the computational education of undergraduate students in bioinformatics
who will face the challenge of analyzing complex, highly multidimensional data
sets in their life science career. This course introduces computational ideas aimed
at solving real biological problems that can be applied and further developed for
the analysis of complex data sets. The goal is to provide an understanding of what
is bioinformatics and what we can do with it by engaging students’ problem
solving skills rather than strictly presenting bioinformatics tools and their use.
3 lectures hours/week, 1 computer lab hour/week
Lecture Topics:
 Genomes
 Gene transcription and regulation
 Evolution
 Phylogeny
 Regulatory networks
 Data Integration & System Biology
 Concluding Remarks
Grading:
2 midterm (25% + 25%) no final exam
Personal project using bioinformatics tools learnt in the lab (25%)
Problem Sets, iClicker questioning during lectures (10%)
Paper presentation (15%).
Required textbook:
Pavel Pevzner and Ron Shamir (2011). Bioinformatics for the Biologist.
Cambridge University Press. ISBN 978-1-107-64887-6. Book available as ebook
at the SFU library.
Recommended textbook: Malcolm Campbell and Laurie J. Heyer (2007).
Discovering Genomics, Proteomics and Bioinformatics (2nd Edition). Benjamin
Cummings. ISBN-13: 978-0805382198
Also required: iClicker
Prerequisite/corequisite: Prerequisites: MBB 321, MBB 322 and one introductory computer course.
"Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112
or e-mail: csdo@sfu.ca)."
All students are subject to and responsible for being familiar with the SFU academic integrity policy which can be found on-line at
http://students.sfu.ca/academicintegrity/index.html
Students are advised to review the plagiarism tutorial found at
http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial
For help with writing, learning and study strategies please contact the Student Learning Commons at http://learningcommons.sfu.ca/