PhD Program in Cancer Biology University of Zurich c/o Institute of Molecular Cancer Research Winterthurerstrasse 190 CH-8057 Zurich Phone: +41 44 635 34 52 http://www.cnz.uzh.ch Molecular and Cell Biology of Cancer 2014 Functional Genomics and Bioinformatics Date Monday, March 17, 2014 Course venue Functional Genomics Center Zurich (FGCZ) Y32H 09.00 - 09.30 General outline Holistic Approaches to Biology and Biomedicine (30 min) 09.30 – 10.30 Introduction to Genome and Transcriptome Analysis Introduction to Genome and Transcriptome Analysis Using Microarrays (30 min) Methods and Tools of Next Generation Sequencing (30 min) 10.30 – 10.50 Break 10.50 – 11.50 Introduction to Proteome Analysis Introduction to Protein Separation and Complexity Reduction Techniques (30 min) Introduction to Quantitative Proteomics (30 min) 12.00 – 13.00 Lunch Break 13.00 – 14.40 Lab Visit Transcriptomics and Proteomics In 4 groups in parallel: - Microarray Workflows (20 min) Next Generation Sequencing (20 min) Quantitative Mass Spectrometry (20 min) FT Mass Spectrometry Technologies (20 min) 14.40 – 15.00 Break 15.00– 16.30 Introduction to Bioinformatics Practical Analysis of Proteomics Data Using Bioinformatics and Statistics (45 min) Introduction to Genome and Transcriptome Bioinformatics (45 min) Closing Remarks & Feedback