Name:____________________________________________________Date:__________________Period:__________
The Basics of the Immune System: T-Cells - Day 7
Objective: Students will be able to describe the basics of T-Cells and their function
QUESTION: If you are not sick, does that mean a virus or a bacteria has not yet entered your body?
Explain your answer.
Answers will vary
Part 1 - Research
1. The above picture describes how a helper T-Cell gets activated. Helper T-Cells do not kill foreign invaders, so how
do you think they help killer T-Cells and memory T-Cells?
Killer T-Cells
Helper T-Cells tell the killer T-Cells what foreign invaders to kill
Memory T-Cells
Helper T-Cells teach the memory T-Cells what the foreign invaders antigens look like
2. Below is a silly cartoon about killer T-Cells. How does the killer T-Cell know what to kill?
Killer T-Cells know what to kill because bacteria and infected
cells have antigens. The killer T-cells recognize these antigens
with their own antibodies and kill them.
Analysis
1. What are the steps that T-Cells have to go through in order to find an kill a foreign cell?
Step 1
A phagocyte eats a bacterial cell
Step 2
The bacteria's antigen goes to the surface of the phagocyte
Step 3
The phagocyte shows the antigen to the helper T-cell
Step 4
The helper T-cell is activated and helps the killer T-cell
Step 5
The killer T-cell finds and kills the foreign invader
2. Below is a graphic organizer showing how T-Cells and B-Cells are created. Use the terms on the right to fill in the
graphic organizer.
Killer T-Cell
Original Lymphocyte
Original
Lymphocyte
Plasma B Cell
T-Cell
B-Cell
T-Cell
Helper T-Cell
Killer T-Cell
Memory T Cell
B-Cell
Memory T Cell
Helper T Cell
Plasma B Cell
Memory B Cell
Memory B Cell
Conclusion:
To be completed on a separate sheet of paper
While answers will vary, a correct response would incorporate most of the terms below as well as specific and nonspecific immune defenses
What has to happen in order for you to get sick with a virus? (be sure to include non-specific defenses, B-Cells and your
knowledge of T-Cells)
 Antibody
 Antigen
 B-Cell
 Killer T Cells
 Mucous
Terms you could include: Check them off as you write.
 Bacteria
 Macrophage
 T Cells
 Helper T Cells
 Hair
How many terms did you use?
Did you explain each term you used?
On a scale of 1-5 (5 being best) what score would you give yourself?
Teacher Score

Memory B Cell
 Plasma Cell
 Memory T Cells
 Skin
 Stomach Acid