Student and instructor reactions to the use of historical short stories in a post-secondary introductory biology course. Jerrid W. Kruse, Michael Clough, Joanne Olson, Jim Colbert. Iowa State University – Ames, IA. 4411 Morningside Ave. Sioux City, IA 51106 This study examines the implementation of historically accurate short stories designed for use in an introductory post-secondary biology course. The stories describe the development of fundamental science ideas and explicitly draw out nature of science concepts through the use of embedded reflective questions. This mixed methods study investigates student reactions to the short stories and how the short stories affect student interest in pursuing science careers. Additionally, the study investigates how use of the short stories has impacted the instructor’s ideas regarding nature of science instruction. Our results indicate that the use of historical short stories in post-secondary introductory biology has positively impacted student interest in science careers and positively influenced the instructor’s intention to include the nature of science in their course. Student interest in science careers significantly increased and many students noted surprise or encouragement when writing about new insights on the nature of science such as: science is collaborative, science is creative, and science does not have to be laboratory-based. The instructor intends to continue to use the short stories in their course due to perceived decrease in student resistance to instruction on evolutionary theory and extensive inclusion of high-level science content within the stories. 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