Antibiotic prophylaxis for urinary catheter insertion 1. Scope of guidance This guidance applies to insertion, removal of change of urinary catheters. The guidance does not cover patient intermittent self-catheterisation. 2. Indications for prophylaxis Antibiotic prophylaxis for urinary catheter insertion is not recommended as routine practice, but should be given in the following situations: Uncatheterised patients who require catheter insertion and are known to have asymptomatic bacteriuria should be given prophylaxis according to the sensitivities of the urinary isolate Insertion for painless (chronic) urinary retention. Send CSU after catheterisation and treat if confirmed UTI. Removal post prostatic surgery Catheter change/removal (long term catheter) IF risk factors are present. Assess risk factors and give prophylaxis if present. The following risk factors are receommended as indications for prophylaxis: - A history of symptomatic urinary catheter-associated infection with previous catheter changes or purulent urethral/suprapubic catheter exit site discharge - Has catheter or meatal/suprapubic catheter exit site colonisation with Staphylococcus aureus (MRSA) - Recatheterisation within 14 days of initial catheterisation - Blocked catheter (manipulation or change) or if traumatic catheterisation (give prophylaxis as soon as possible and within 30 minutes) - Catheter change in neutropenic patients 3. Situations where prophylaxis is NOT required Prophylaxis prior to urinary catheter insertion / removal / change is NOT required for: Catheter insertion/removal in patients with endocarditis risk factors Catheter insertion/removal in patients with established prosthetic joints Catheter insertion for painful (acute) urinary retention Removal of catheter (unless post prostatic surgery or S.aureus colonised urine or meatal sample) Long term catheter insertion (unless urinary tract infection or known asymptomatic bacteriuria at time of insertion) Suprapubic catheter insertion (provided no UTI at time of insertion) Change/removal of long term catheter (unless risk factors as above) 4. Patients with established urinary tract infection: Patients with urinary tract infections who require catheter insertion should be started on antimicrobial treatment prior to catheterisation wherever possible Catheterised patients with urinary tract infections should be commenced on empirical treatment prior to catheter changes 5. Choice of prophylactic antimicrobial agent If available, choice of agent is determined by sensitivities of recent isolate from catheter urine Otherwise, give Gentamicin 2mg/kg IV (max 160mg) immediately prior to catheter change/insertion