Midwest Regional Chapter Society of Toxicology Spring 2010 Newsletter The MRC/SOT Proudly Presents the Annual Spring Meeting scheduled for Friday, May 21, 2010: “The Central Nervous System as a Target of Toxic Injury” It is with great pleasure that we extend an invitation for you to join us for the upcoming Spring meeting of the Midwest Regional Chapter of the Society of Toxicology. ~See inside for meeting details~ 1 28th Annual MRC/SOT Spring Meeting 21 May 2010 Marriott Lincolnshire Plans for the 28th Annual Spring Meeting of the Midwest Regional Chapter of SOT are being finalized. The meeting will be held on Friday, May 21 at the Marriott Hotel and Resort in Lincolnshire, IL. The theme for this year’s meeting is “The Central Nervous System as a Target of Toxic Injury”. The Program Committee has lined up an outstanding panel of speakers to cover this emerging and important topic. A copy of the tentative program along with the Registration form and directions to the meeting site are attached. In addition to the featured symposium, the meeting will also include the presentation of the Young Investigator Award and the Kenneth P. Dubois Career Achievement Award, as well as a poster session featuring the annual Victor A. Drill student research competition. The winner of the competition will receive up to $1500 toward expenses for attending the SOT Annual Meeting. All students affiliated with institutions in the MRC’s geographical region are encouraged to submit abstracts for the poster competition. The abstracts and posters may be on either original work or work that has been presented at the 2010 national SOT meeting in Salt Lake City. Abstracts should be submitted along with registration materials to: Molly Weiler, Ph.D., DABT Covance Laboratories Inc. Nonclinical Safety Assessment Process Excellence, Mail Code 42 2201 Kinsman Blvd. Madison, WI 53704 Phone: 608-242-2626 For further information regarding the meeting, please contact the 2010 Program Chairman, Matthew Schroeder at Matthew.Schroeder@covance.com The Awards Committee is also soliciting applications for the MRC Young Investigators Award and nominations for the Kenneth Dubois Career Award. Information regarding these awards and the application/nomination processes can be found on the MRC-SOT website. 2 Midwest SOT Spring Meeting (21 May 2010) The Central Nervous System as a Target of Toxic Injury 7:00-8:00 Registration/Breakfast 8:00-8:15 Welcome 8:15-9:00 Dr. Paul Carvey, PhD, Rush Title: “The Blood Brain Barrier in Neurodegenerative Disease.” 9:00-9:45 9:45-10:30 11:35-11:50 Erin Shanle, University of Wisconsin-Madison Title: “Growth inhibition of triple Negative breast cancer by dietary phytoestrogens.” 2009 Young Investigator Award Presentation Dr. Mary Jeanne Kallman, PhD, Covance Title: “Understanding A Safety Margin for Convulsion.” 11:50-12:20 Graduate Student Poster Session 12:20-1:00 Lunch Dr. Gary Isom, PhD, Purdue University Title: “Cyanide-induced neurodegeneration and activation of mitochondrial mediated cell death.” 1:00-1:30 Business Meeting/Student Poster Awards 1:30-2:15 Dr. Jeffrey Johnson, PhD, University of Wisconsin Title: “Halting the Progression of Neurodegenerative Diseases: What does Nrf2 have to do with it?” 2:15-3:00 Dr. Alok Sharma, BVSc, MVSc, MS, PhD, Diplomate ACVP Diplomate ABT, Covance Title: “Correlation of Histopathologic Findings with Genomic and Pathway Changes in a Kainic Acid Induced Rat Model of Epilepsy.” 3:00-3:15 Concluding Remarks 10:30-10:50 Refreshment Break 10:50-11:35 Dr. Rikki Waterhouse, PhD, Abbott Title: “Translational Non-Invasive Imaging of Processes related to Neurodegeneration and Neuroprotection.” 3 MEETING INFORMATION Regular Member: $100 (if postmarked before 5/6/2010) $120 (if postmarked 5/6/2010 or after) Non-Member: $130 (if postmarked before 5/6/2010) $140 (if postmarked 5/6/2010 or after) Full-Time Students: $15 (if postmarked before 5/6/2010) $30 (if postmarked 5/6/2010 or after) Hotel Rooms A limited number of rooms are being held for this conference. The rate is $139.00 per night. Reservations for Thursday and/or Friday can be made by calling (847) 634-0100. Ask for the “Society of Toxicology” block. 4 Directions to Conference Site Lincolnshire Marriott Resort 10 Marriott Drive Lincolnshire, Illinois 60069 (847) 634-0100 From the North 1-94 south; exit Half Day Road; turn right (west); turn left on Milwaukee Avenue; turn left on Marriott Drive. From the South 1-94 north; exit Half Day Road; turn left (west); turn left on Milwaukee Avenue; turn left on Marriott Drive. From the West 1-90 east; 1-294 north; 1-94 north; exit Half Day Road; turn left (west); turn left on Milwaukee Avenue; turn left on Marriott Drive. For additional information, contact Matthew.Schroeder@covance.com. 5 2010 MRCSOT Spring Meeting Registration Form Advance Registration Deadline: May 6th, 2010 Fees Regular Member: $100 Non-Member: $130 Full-Time Students: $15 Hotel Rooms A limited number of rooms are being held for this conference. Registration Form Return the form below with payment by 5/6/2010 to: Molly Weiler, Ph.D., DABT Covance Laboratories Inc. Nonclinical Safety Assessment Process Excellence, Mail Code 42 3301 Kinsman Blvd. Madison, WI 53704 Phone: 608-242-2626 Registration will be permitted at the conference. MRC/SOT 2010 Spring Meeting Registration Form Name: ___________________________________ MRC-SOT Member _____ Yes _______No Title/Position/Company __________________________________________________________ Phone Number _________________________ E-mail address ___________________________ Address ______________________________________________________________________ City ____________________________________ State _____________ Zip _______________ *Make checks payable to MRC-SOT* Fee Enclosed (please check): $100 (if postmarked before 5/6/2010) ___ $120 (if postmarked 5/6/2010 or after) ___ Non-Member: $130 (if postmarked before 5/6/2010) ___ $140 (if postmarked 5/6/2010 or after) ___ Full-Time Students: $15 (if postmarked before 5/6/2010) ___ $30 (if postmarked 5/6/2010 or after) ___ Regular Member: Is a receipt required for this registration? _____Yes 6 _____ No Midwest Regional Chapter Society of Toxicology Abstract Form for the 2010 Spring Meeting Entry Instructions Return abstract forms with registration materials to: Molly Weiler, Ph.D., DABT Covance Laboratories Inc. Nonclinical Safety Assessment Process Excellence, Mail Code 42 3301 Kinsman Blvd. Madison, WI 53704 Phone: 608-242-2626 Abstracts in any area of toxicology are acceptable. Use standard SOT guidelines for format. Place original copy on this form. Leave a double space between the heading and the abstract. Single space abstract text. Type within the rectangle. Use type no smaller than 12 pitch. Please proof carefully! We will return to the author any abstract that needs retyping. Submit the original and two clear copies. There is no abstract fee. Deadline for entry is April 9, 2010. All abstracts are accepted for display unless otherwise notified. 1. Author Information _______________________ Name _____________________________ Organization _____________________________ Address _____________________________ City State Zip Code ______________________________ Telephone No./Fax No. 2. MRC/SOT Member ? Yes___No___ 3. Is this poster a candidate for the Victor A. Drill Award? Yes ____No ____ 4. Has this poster been presented elsewhere? Yes___No___ All presentations will be posters on 4’by 6’ boards at the designated time. The Awards Committee will judge the entries. The winner will be announced at the conclusion of the poster session. 7 President’s Message Greetings. I hope you have had an enjoyable Winter and that the snow and gloomy weather has not dampened your spirits. As we emerge from Winter’s grip, it is time to start thinking about the upcoming Spring Meeting of the Midwest Chapter of the Society of Toxicology, which will be held on Friday, May 21 at the Marriott Resort in Lincolnshire, IL. The Program Committee, under the direction of President-elect Matt Schroeder, has organized a very interesting program on the topic “The Central Nervous System as a Target of Toxic Injury”. The program includes an outstanding panel of speakers who are recognized leaders in the field. I sincerely hope that you will all be able to attend. The detailed program, registration materials, directions and lodging information for the meeting can be found elsewhere in this Newsletter as well as on the MRC website. For planning purposes we are asking that registration materials be submitted before May 6, 2010. A major part of the Spring Meeting, of course, is the presentation of the chapter’s annual awards. The Executive Committee is now soliciting applications and nominations for the various awards including: Kenneth DuBois Career Achievement Award, Victor Drill Award and the Young Investigator Award. Descriptions of the awards and application materials may be found elsewhere in this Newsletter and on our website. Deadline for receipt of applications/nominations is April 9, 2010. Our 2009 Fall Meeting, that was held at Covance Laboratories in Madison, WI on November 20, was a huge success. About 80 people attended the meeting, which focused on the topic “Cardiovascular Toxicology”. I wish to extend my sincere thanks to all of the sponsors and individuals whose efforts contributed to the success of the meeting. Special thanks go to Matt Schroeder, who served as Program Chair and on-site coordinator. The Program Committee will soon begin planning the 2011 Spring Meeting that will be held in Lincolnshire on May 21, 2011. We encourage members to submit ideas for possible topics and speakers for the meeting. Also, members are encouraged to submit ideas for topics and possible venues for next year’s Fall Meeting. Hosting the Fall Meeting is a great opportunity to showcase your facilities and organization. Please feel free to contact anyone on the council with your questions or ideas. Please encourage your colleagues to become members of the chapter; one does not have to be a member of National SOT to become a member of our regional chapter. Membership and application materials are posted on our website. Finally, I ask that all of you please consider running for office or serving on one of the chapter’s committees. Our by-laws are posted on the web site and this is a great way to learn more about the duties of the officers and councilors. Since so much of the work of the Council and committees is conducted electronically, it has become much easier to participate. I look forward to seeing as many of you as possible on May 21 st, in Lincolnshire. Walt Prozialeck 8 **MRC/SOT AWARDS** The Midwest Regional Chapter is proud to recognize the efforts of toxicologists who work and study in the Midwest. Three annual awards are presented that highlight their achievements: Kenneth P. DuBois Award Presented to an active toxicologist from the Midwest region that has demonstrated outstanding contributions throughout his/her career. Candidates must have demonstrated a sustained and high level of achievement in the field. Written nominations are required. Nominations due April 9, 2010 The 2009 Kenneth P. DuBois Award was presented to Barbara Struthers, of BJ Struthers, Ltd. Victor A. Drill Award Presented for the best student poster presentation at the annual spring meeting of the Chapter. The winner receives a paid trip (expenses reimbursed up to $1500) to the following year’s National SOT meeting. Abstracts due April 9, 2010 The 2009 first place poster Victor Drill Award was presented to Qing Liu who received a $1,500 grant for his poster entitled “Time and dose-dependent effects of dietary TCDD in Juvenile Rainbow Trout.” The second place poster Victor Drill Award was presented to Sonya Bolker who received $100 for her poster entitled “Enrichment of broccoli and tomato with bioactive components: effects on bioactivity markers in vivo.” Young Investigator Award Presented for the best student research proposal. The winner receives $1500 to put towards their proposed research project and presents their results at the following year’s MRC/SOT Spring meeting. Proposals due April 9, 2010 This award was presented to Erin Shanle for her research proposal on “The impact of BPA on TripleNegative Breast Cancer Therapy”. Erin is a graduate student in Molecular and Environmental Toxicology at the University of Wisconsin – Madison. The Awards will be presented at the Annual Spring 2010 Meeting of the Chapter . Information about the three awards, as well as application forms, are found on our website (www.toxicology.org/memberservices/regionalchapter/midwest/). Any further questions may be directed to the Executive Committee. 9 Thank you to our sponsors who have supported MRC over the past year: General Support Abbott Laboratories Charles River Laboratories CorDynamics Covance Midwest BioResearch Midwestern University Department of Pharmacology Reid Patterson Consulting Robin Guy Consulting, LLC Society of Toxicology National Headquarters WIL Research Laboratories Also special thanks to Vicki Sears and Peter Lamar, from Midwestern University, for logistical support 10 Regional Chapter Graduate Committee (RC-GC) Greetings Midwest Regional Chapter! My name is Ofek Bar-Ilan and I am the Regional Chapter/Special Interest Group Graduate Committee (RC/SIG-GC) representative for the Midwest Regional Chapter (MRC)-SOT. As an ad hoc committee of the national Society of Toxicology, the RC/SIG-GC was created to serve as a student liaison between the regional and national SOT chapters in order to encourage student involvement in SOT. If you are a student and have an active interest in toxicology, we encourage you to attend the next MRC-SOT meeting on May 21, 2010 at the Lincolnshire Marriott Resort in Lincolnshire, IL. Even though you do not need to be a member of the Midwest Regional Chapter to attend the meeting or present a poster, there are several benefits to becoming a student member. Student members have access to several services provided by the MRC-SOT, are eligible for student travel awards such as the Victor A. Drill Award for best poster presentation and the Young Investigator Award for the most innovative research. You also benefit from networking with other scientists and potential employers at the regional meetings. Besides, membership dues are only $10! To become a member, you can either download an application form from our website (which does not require national membership) or designate your choice to join while paying national SOT dues. Please feel free to email me with any questions you have about regional and national SOT student awards (which are due April 9, 2010) and meetings or volunteer opportunities at the annual SOT meeting. It has been my pleasure serving as your student representative for the past two years. This will be my last year serving as the student representative for MRC as I will be taking over as the chairperson for the SOT Student Advisory Committee (SAC) in May 2010. Thank you and good luck! Hope to see you May 21! Ofek Bar-Ilan RC-GC Representative SAC Chairperson-elect Division of Pharmaceutical Sciences University of Wisconsin-Madison 777 Highland Ave Madison, WI 53705 Phone: 608-262-4525 Email: barilan@wisc.edu 11 INTERESTED IN SERVING ON THE MRC/SOT EXECUTIVE COMMITTEE? Annual elections are held to fill various vacant positions in the MRC/SOT executive committee. Nominations are accepted annually for vacant positions. For the 2010-2011 the following executive committee positions were filled: President-elect, Christina Wilson; Secretary, Thomas Mably; Councilors, Greg Erexson and Michael Biehl. President Walter Prozialeck Midwestern University Phone: 630-515-6385 wprozi@midwestern.edu Councilors Jane Fagerland Abbott jane.fagerland@abbott.com Oliver Pelz BP Corporation Phone: (630) 420-3650 (630) 420-5375 oliver.pelz@bp.comorganization: President-Elect Matthew Schroeder Covance Laboratories Phone: 608.310.8222 Matthew.Schroeder@covance.com Chair: Program Committee Susan Henwood Covance Laboratories Phone: 608.241.7221 susan.henwood@covance.com Past President Peter J. Thomford, Ph.D, DABT. Covance Laboratories Telephone: 608.395-3683 Peter.Thomford@covance.com Chair: Nominating/Awards Committee Lise Loberg Abbott Laboratories Phone: 847.937.5978 Lise.Loberg@abbott.com Secretary Louette Rausch, M.S. Akzo Nobel Phone: (312) 544-7061 louette.rausch@akzonobel.com Chair: Newsletter/Communications/Membership Committee Regional Chapter Graduate Committee Representative Ofek Bar-Ilan Division of Pharmaceutical Sciences University of Wisconsin-Madison Phone: 608-262-4525 barilan@wisc.edu Treasurer Molly Weiler, Ph. D. Covance Laboratories Phone: (608) 242-2626 molly.weiler@covance.com The MRC-SOT newsletter is published biannually in both print and electronic formats as a service to the toxicology community of the Midwest. Contributions are welcome! Please address any questions, comments or contributions to Louette Rausch at the email address above. 12 Congratulations to Our Newly-Elected Officers! 2010-2011 New Officer Contact Information Christina Wilson, PhD, President Elect Department Head, Toxicology Section Clinical Assistant Professor Purdue University Animal Disease Diagnostic Laboratory 406 South University West Lafayette, IN 47907 Phone: (765) 494-7440 Fax: (765) 494-9181 E-mail: wilsonc@purdue.edu Gregory L. Erexson, Ph.D., Diplomate, ABT, Councilor Baxter Healthcare Corporation Pathobiology/Toxicology Technology Resources/Life Sciences 25212 W. Illinois Route 120 Maildrop WG2-2S Round Lake, IL 60073 phone: 847-270-5579 fax: 847-270-5559 E-mail: greg_erexson@baxter.com Michael L. Biehl, DVM, PhD, MBA, Councilor Clinical Professor of Toxicology College of Veterinary Medicine University of Illinois 1008 West Hazelwood Drive Urbana, IL 61802 office: (217) 244-4649 cell: (217) 714-7019 biehlml@illinois.edu Thomas A. Mably, PhD, DABT, Secretary Program Manager Covance Laboratories, Inc. 3301 Kinsman Blvd. Madison, WI 53704 Tel: 608-395-3619 Fax: 608-242-7971 thomas.mably@covance.com 13