Topic: - Management of iron deficiency anemia and its management with
pandughna vati and dhatriyarista.
Title: - An Etiopathological study of pandu roga w. s. r. to iron deficiency anemia
and its management with Pandughna vati and Dhatriyarista.
Dr. Urvi Dave has submitted her dissertation to Gujarat University,
Jamnagar (Gujarat, India) in 2007 For M. D. in Rognidan & Vikrutividyan. Her
research center was I.P.G.T. & R. A. Jamnagar (Gujarat, India)
Dr. Urvi has studied total 46 patients of Anemia, out of which 40 patients
was completed the treatment. Patients were divided into three groups-Group-A,
Group-B & Group - C.
In Group A, total 18 patients were registered, 2 patients were LAMA (Left
against Medical Advise) and 16 patients completed the treatment.
In Group B, total 17 patients were registered, 4 patients were LAMA and 13
patients completed the treatment.
In Group C (control/standard group), 11 patients were registered and no
LAMA.
18 Patients of GROUP A were given “Pandughna vati” (Anubhuta) in the
Dose of1 gm twice a day after meal with water .Duration of the treatment was 6
weeks.
17 Patients of GROUP B were given “Dhatriyarista” (Cha. Chi. 16/111113) in the Dose of 20 ml with water twice a day before meal. Duration of the
treatment was 6 weeks.
In control/standard Group C, 11 patients were treated with the drug Ferrous
sulphate in the dose of 150 mg Three times a day with water. Duration of the
treatment was 6 weeks
Detailed history was taken and a special research Performa was prepared for
the study incorporating all the relevant points from both Ayurvedic and Modern
views. Case paper included Prakruti, Sara examination and ashtavidha
examination.
Female Patients having Hb% below 12 % and male Patients having Hb%
below 13% were selected. Patients between the age group of 15-50 years were
selected for the study.
Following investigations were carried out- i.e. Hematological, Hb %, TC,
DC, TRBC, ESR, PCV, and Blood Indices: MCV, MCH, MCHC, and Serum Iron
Level & Total Iron Binding capacity Routine and Microscopic Urine and
Biochemical examinations were excluded.
After completion of 6 weeks, analysis was done and research was concluded
in the following manner1) 65.21% belonged to 21-40 years age group.
2) 82.60% patients were female.
3) 80.43. % patients were married.
4) 56.52% patients belonged to middle class and 56.12% were householder
5) 26.08% patients were having higher secondary education.
6)54.73% patients were from urban area.
7) 91.30 % patients were Hindu and 89.13% patients were vegetarian
8) 65.21% were having poor appetite.
9) 30.43% were indulging excess salty food whereas 28.24% were indulging
excess sour food.
1o) 60.86 % patients were having Addiction of tea
11) 47.82 % patients were suffering from constipation which indicated Krura
koshtha.
In present study mostly Microcytic Anaemia was found, size of RBCs was
smaller than the normal.
Group A patients were treated with Pandughna vati and symptoms of Pallor
(53.50%), weakness (44.73%), palpitations (52.40%), giddiness (62.30%), and
muscle cramps (65.84%) were significantly reduced in the 16 patients.
Statistically significant relief was observed in the symptoms of peri-orbital
oedema (57.15%), anorexia (72.65%), and pyrexia (80%) in Group A patients.
Regarding Hematological investigation significant improvement was noted
in Hb% (2.6%), MCV (4.63%), MCHC (2.38%), and ESR (10.28%) and in TIBC
(3.16%).
Statistically insignificant results were obtained in signs and symptoms like
dryness (21.80%), dyspnoea (52.54%) regarding investigations insignificant results
were noted in TRBC (1.6%) MCH (3.5%) & serum Iron level (3.16%) in the
patients of Group A.
In patients treated with Dhatriyarishta (Group B), highly significant results
were found in Pallor (56.73%), weakness (55.35%), giddiness (71.42%) and
muscle cramps (53.84%). Significant result were found in palpitations (54.65%),
Periorbitaledema (57.14%),dryness(33.33%),dyspnoea(50%),anorexia(33.33%)and
pyrexia (14.86%). Regarding investigations significant result were found in TRBC
(2.77%) count and TIBC (4.60%).
In control Group Highly significant result were found in
Panduta(64%),Daurbalyta(65.5%),Bhrama(80.70%),Shunakshikutashotha(46.50%)
,Rukshata(29.10%), Aruchi(62.20%), Pindikodweshtana (cramps in calf muscles
69.20%), Shwasa ( exertional dyspnoea,79.05%) and Jwara ( pyrexia 66.67%).
Overall comparison showed that best results were obtained in both the trial
compounds in the form of better statistical significance and percentage relief. But
as we know Ferrous sulphate is standard control drug for Iron Deficiency Anaemia
it showed better results in comparison to the trial compounds
Data entry on14/02/12
Given by Dr. Chobhe
Edited on: 27/3/12
Edited By Dr Chobhe