International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
PROGRAM OUTLINE
Program in Shanghai
(After tifle the brackets show the page number on the abstract book)
November 4 Reception and Opening Ceremony
Time: 19:00~21:00, pm, November 4
Reception dinner and opening Ceremony
Place: Giu Tsai Tian Restaurant, Floor 2, Huashia Hotel
Chair: Prof. Frank Xiaohui Zhang
General Chair, Prof. Masahiro Sokabe: Message from General Chair (1)
Shanghai Local Leader: Welcome address
November 5 Plenary Lectue Ⅰ~Ⅶ
Time: 8:30~10:25 am, November 5
Plenary lecture (I-II)
Place: Huashia Hall, Floor 3, Huashia Hotel
Chair: Prof. Masahiro Sokabe
(A plenary lecture for 45 minutes including 5 minutes’ discussion)
I Shu Chien (USA): Role of Stress Direction and Mechanotransduction in Vascular Homeostasis (5)
II Chwee Teck Lim (Singapore): Mechanopathology of an Human Infectious Disease (11)
Tea Break 10:25-10:35
Time: 10:35-12:30Am, November 5
Plenary lecture (III-IV)
Place: Huashia Hall, Floor 3, Huashia Hotel
Chair: Prof. Jimmy K Hsia
(A plenary lecture for 45 minutes including 5 minutes’ discussion)
III Masahiro Sokabe (Japan): How do forces activate mechanosensitive channels in bacterial and eukaryotic cells?
(14)
IV Ching Kung: The Molecular Basis of Mechanosensation (9)
Lunch
Place: Giu Tsai Tian Restaurant, Floor 2, Huashia Hotel
Time: 12:30~13:30, pm, November 5
-5-
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Time: 13:30-16:00, pm, November 5
Plenary lecture (V-VII)
Place: Huashia Hall, Floor 3, Huashia Hotel
Chair: Prof. Chwee Teck Lim
(A plenary lecture for 45 minutes including 5 minutes’ discussion)
V Mian Long (China): Mechanobiology of Mammalian Cellular Responses to (Micro-) gravity (13)
VI Jimmy K. Hsia (USA): Measuring Cell Mass and Growth Using Micro-Nanotechnology (7)
VII Xiaohui (Frank) Zhang, PhD (China): Probing the biomechanical properties of single protein molecules (15)
Tea Break 16:00-16:10 pm, November 5
Time: 16:10~18:00, pm, November 5 Lectures of mini symposia and sessions
Schedule on November 5 Afternoon (16:10~18:00) Pm
原宾馆中文名
English Names
Nov. 5,
PM
16:10~18:00
华夏厅
Huashia Hall
Mini
Symposium J
第一会议室
Room I
Mini
Symposium C
第二会议室(甲)
Room II (A)
Mini
Symposium F
第三会议室
Room III
Mini
Symposium H
报告厅
Room IV
Mini
Symposium I
营都厅
Room V
Mini
Symposium Q
Time: 16:10~18:00, pm, November 5
Place: Huashia Hall
Mini Symposium J: Roles of TRP channels in mechanotransduction (73)
Organizer and Chair: Prof. Keiji Naruse & Prof. Masahiro Sokabe (Japan)
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
Involvement of TRPV2 channel in stretch sensing of vascular endothelial cells (74)
Keiji Naruse
Mechanosensitive TRP channels in cardiovascular function and disease.(75)
Ryuji Inoue, Yaopeng Hu, YubinDuan, Yuko Imai, KyoheiItsuki
Chlamydomonas behavioral response triggered by mechanoreception with a TRP channel in flagella (76)
Kenjiro Yoshimura, Masahiro Sokabe
Role of TRPV1 in mechanically induced pain. (77)
Murase S, Ota H1, Katanosaka K, Kubo A, Queme F, Matsuda T, Taguchi T, Mizumura K
Role of STIM1 in regulation of airway smooth muscle functions (78)
Satoru Ito, Nobukazu Suganuma, Yoshinori Hasegawa
Time: 16:10~18:00, pm, November 5
Place: Room I
Mini Symposium C: Hydrodynamic forces vs. protein structure (34)
Organizer and Chair: Prof. Wojciech Dzwolak (Poland)
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
Chiral bifurcation: a new phenomenon induced in fibrillating insulin by vortex forces (35)
Wojciech Dzwolak
Mechanostability of Proteins and Virus Capsids (36)
Marek Cieplak
-6-
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Theoretical models of protein dynamics in hydrodynamic flows (37)
Piotr Szymczak
Characterizing the Effects of Shear Flow on Protein Structure (38)
Ewan W. Blanch
Time: 16:10~18:00, pm, November 5
Place: Room II (A)
Mini Symposium F: Mechanosensition and tension regulation: signaling mechanism (54)
Organizer and Chair: Prof. Xiaoqing Yao (Hong Kong, China)
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
TRPV4-TRPC1 heteromeric channel: its property and function (55)
Xin Ma, Xiaoqiang Yao
TRPC5 is a pressure-sensor in aortic arch baroreceptors (57)
Bing Shen, Ching-On Wong, Yang-Chao Chen, Xin Ma, Yu-Bun Man, Xiaoqiang Yao
Characteristics and mechanisms of fluid pressure-induced Ca2+ waves in atrial myocytes (58)
Joon-Chul Kim and Sun-Hee Woo
Why are cancer tissues rigid, but cancer cells soft-- mechanobiology of cancer (59)
His-Hui Lin, Hans Harn, Ching-Yi Liu, Meng-Ru Shen, Ming-Jer Tang,
Time: 16:10~18:00, pm, November 5
Place: Room III
Mini Symposium H: Methodologies of molecular mechanobiology and their application (62)
Organizer and Chair: Xiaohui (Frank) Zhang, China & Hongbin Li (Canada)
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
Biophysical Mechanisms of Human Integrin α4β7 -Mediated Leukocyte Rolling and Firm Adhesion (63)
Yanbo Zhang, Hao Sun, Jianfeng Chen, Vincent T. Moy and Xiaohui Zhang
Single-molecule derivation of salt dependent base-pair free energies in DNA.(64)
Steven Smith, PhD
Protein Mechanics of Artificial Elastomeric Proteins: From Single Molecule to Biomaterials (65)
Hongbin Li
Effects of the mechanical properties of substratesonthe in vitro formation of bile ductsby biliary epithelial
cells (66)
Ryo Sudo, Kaoru Matsuo, Tomoya Komatsu, Mariko Ikeda, Toshihiro Mitaka, Kazuo Tanishita
Time: 16:10~18:00, pm, November 5
Place: Room IV
Mini Symposium I: Mechanobiology of actin cytoskeletons (67)
Organizer and Chair: Prof Hitoshi Tatsumi (Japan)
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
The role of Actin filaments as a force-transmitter and a force-sensor (68)
Hitoshi Tatsumi
Sensing Substrate Rigidity by Mechanosensitive Ion Channels with Stress Fibers and Focal Adhesions (69)
Takeshi Kobayashi, Masahiro Sokabe
-7-
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Imaging for Cellular Mechanics: Dynamic Behavior of Cytoskeletal Networks and Cellular Contractile
Force (70)
Takeomi Mizutani
On the roles of actin stress fibers on mechanical stabilization of the nucleus and intranuclear DNA (71)
Kazuaki Nagayama, Yuki Yahiro and Takeo Matsumoto
Cellular Tensional Homeostasis Regulated by Nonmuscle Myosin-II (72)
Shinji Deguchi, Tsubasa S. Matsui, Roland Kaunas, Masaaki Sato
Time: 16:10~18:00, pm, November 5
Place: Room V
Mini Symposium Q: Biomechanics and Tissue Engineering (108)
Organizer and Chair: Prof. Wei Liu & Luan-feng Pan, (China）
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust schedule)
Turn dermis into tendon-like tissue by in vivo stretching (109)
Yanjie Zhang, Bin Wang, Yilin Cao，Wei Liu
Effects of hSMCs on HUVECs in A Novel Co-culture System (110)
Shui Liu, Luanfeng Pan, Yin Yu, Chang Wang, Guoqiang Wu, Lei Cui
A proteomic analysis of engineered tendon formation under dynamic mechanical loading in vitro (111)
Yongkang Jiang, Guangdong Zhou, Wenjie Zhang, Yilin Cao,Wei Liu
Elongated cell morphology and uniaxial mechanical loading contribute to tenocyte microenvironmental
niche (112)
Jie Li1, Ji Zhu, Guangdong Zhou, Wenjie Zhang, Yilin Cao, Wei Liu
Construct engineered tendons with muscle derived cells （113）
Bo Chen, Guangdong Zhou, Wenjie Zhang, Yilin Cao, Wei Liu
Supper: Time:18:00~19:00 pm, November 5, Giu Tsai Tian Restaurant floor 2, Huashia Hotel
Time: 8:30~12:30Am, November 6 Lectures of mini symposia and sessions
Schedule on November 6 Morning (8:30~12:30)
English
Names
Nov. 6, AM
8:30~10:25
Huashia Hall
Room I
Room II (A)
Room III
Room IV
Room V
Special
Session T (1)
Mini
Symposium
R(1)
Mini
Symposium
B
Session
Alpha (α1)
Mini
A(1)
Symposium
Session Delta (δ1)
Mini Symposium O(1)
Nov. 6 AM
10:35~12:30
Special
Session T (2)
Mini
Symposium
R(2)
Mini
Symposium
K
Symposium
Session Delta (δ2)
Mini Symposium O(2)
Tea break (10:25-10:35AM)
Session
Alpha (α2)
Mini
A(2)
Time: 8:30~10:25 Am, November 6 Place: Huashia Hall
Special Session T (1)
Cerebration for Honorary Professor Shu Chien’s 80th Birthday
（贺钱煦院士 80 华诞论文报告会开幕式）(133)
Chairs: Prof. Nan-ping Wang and Prof. Zong-lai Jiang
Prof. Nan-ping Wang: 介绍钱煦院士科学成就(134)
Brief Introduction of Prof. Shu Chien’s Contribution to Sciences (138)
-8-
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Prof. Shu Chian: Making address
Taking all together photo (Keep quiet, the other room is still making lectures)
Time: 8:30~10:25 Am, November 6
Place: Room I
Mini Symposium R(1): Multiscale modeling of cellular Mechanobiology & Cell Mechanics (115)
Organizer and Chair: Prof. Xiaobo Gong (China) & Prof. Chwee Teck Lim (Singapore）
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
On the Development of Multiscale Thrombosis Simulator: FOR THE NEXT-GENERATION
SUPERCOMPUTER IN JAPAN (123)
S. TAKAGI, S. II, S. SHIOZAKI, K. SUGIYAMA, S. GOTO, Y. MATSUMOTO
Combined Computational and Experimental Study of Erythrocytes and Related Diseases (120)
Ming Dao
Force-dependent dynamics of focal adhesion and its role in the migration speed of cell (124)
Baohua Ji
Quantifying Gastrointestinal Smooth Muscle Cell Mechanics (126)
Martin Buist, Chung Cheuk Wang, Viveka Gajendiran
Development of GPU Computing for Simulating Dense Suspension of Capsules (125)
Yohsuke Imai, Daiki Matsunaga, Takuji Ishikawa, Takami Yamaguchi
Time: 8:30~10:25, Am, November 6
Place: Room II(A)
Mini Symposium B：Physiological and pathophysiological roles of shear stress in vascular endothelial cells
(30)
Organizer and chair: Prof. Toshio Ohhashi
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
AGING AND SHEAR-DEPENDENT REGULATION OF MESENTERIC LYMPHATIC PUMPING (31)
Anatoliy A. Gashev, Tony J. Akl, Gerard L. Coté, Takashi Nagai.
Endothelial mechanotransduction and its role in the control of vascular functions (32)
Kimiko Yamamoto and Joji Ando
New proposed concept of shear stress-mediated carbon dioxide exchange in human lungs (33)
Yoshiko Kawai, Toshio Ohhashi
Time: 8:30~10:25, Am, November 6
Place: Room III
Session (Alpha α1)
Biophysics and Molecular Biology of force sensing and generation
Chairs: Chairs: Prof. Ming-jer Tang, Prof. Chao-min Cheng, Prof. Chun Yang
Introduction of Session Alpha (α)
20 abstracts from Part A: Basic Mechanobiology (I Biophysics and Molecular Biology of force sensing and
generation), among 20 abstracts, 13 for oral, 5 for poster, and 2 for text exchange.
-9-
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Oral Session (Alpha α1)
Title: Biophysics and Molecular Biology of force sensing and generation
（13 oral presentations, every presentation for 15 minutes including 3 minutes discussion）
(1) Biophysical Linkage between Local Mechanical Properties and Global Cellular Responses in Living
Fibroblasts: Actin Cytoskeleton Perspectives(156)
Hans I-Chen Harn, Yang-Kao Wang, Hsi-Hui Lin, Chao-Min Cheng, Ming-Jer Tang
(2) Interaction of the Antimicrobial Peptide NK-2 with Phospholipid Membranes (157)
Sanat Karmakar, Reinhard Lipowsky, Rumiana Dimova
(3) Sensing Substrate Rigidity by Mechanosensitive Ion Channels with Stress Fibers and Focal Adhesions
(158)
Takeshi Kobayashi, Masahiro Sokabe
(4) Regulation of Focal Adhesion Kinase through Syndecan-4 under Mechanical Stimulation (159)
Robert L. Steward Jr, Robert M. Bellin, Philip R. LeDuc, Chao-Min Cheng
(5) Fluid flow stress influences distribution and expression of polycystin1/2 in MLO-Y4 and MC3T3-E1
cells (163)
Jian Zhang, Hui-yun Xu, Jia-wei Wu, Peng Shang
(6) Fibronectin is involved in gravity-sensing of osteoblast like cell (164)
Jingbao Li, Yanan Li, Liang Wang, Mingzhi Luo, Airong Qian and Peng Shang
(7) THE INFLUENCE OF PHYSICAL AND PHYSIOLOGICAL CUES ON ATOMIC FORCE
MICROSCOPPY ASSESSMENT TO CELL(166)
Yu-Wei Chiou, Hsi-Hui Lin, Ming-Jer Tang, Ming-Long Yeh
Time: 8:30~10:25 Am, November 6
Place: Room IV
Mini Symposium A (1) : Mechanosensitive Channels and Proteins (18)
Organizers and Chairs: Prof. Boris Martinac and Prof. Yue-zhou Li
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
TRPV4: Mechanosensitivity, Physiology and Pathology (20)
Stephen Loukin, Xinliang Zhou, and Ching Kung
Structure of a bacterial large-conductance mechanosensitive channel: insights into the gating-related
conformational changes (21)
Zhenfeng Liu*, Chris S. Gandhi & Douglas C. Rees
Soft ECM triggers integrin activation and internalization: a mechanism of induction of stem cell
differentiation by ECM elasticity (22)
Jing Du, Xiaofei Chen, Xudong Liang, Guangyao Zhang, Xi-qQiao Feng, Shu Chien, and Chun Yang
Ventricular pressure clamping and pressure-induced arrhythmias (23)
Haixia Huang, Hua Wei, Ping Liu, Wei Wang, Frederick Sachs and Weizhen Niu
Mechano-activation of CFTR anion channel in simple epithelial cells (24)
Pingbo Huang
- 10 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Time: 8:30~10:25Am, November 6
Place: Room V
Session (Delta δ1)
Special topics in mechanobiology
Chairs: Prof. Shiyi Chen, Prof. Yi-xian Qin, and Prof. Shinji Duguchi
Introduction of Session Delta (δ): Special topics in mechanobiology
12 Abstracts from Part C: Special topics in mechanobiology (among 12 abstracts, 7 for oral and 5 for text
exchange), 5 ones belong to VII Special topics (5 abstracts, 3 for oral and 2 for text exchange), and the other
7 ones belong to VIII Other topics in biophysics, mechanobiology, and biomechanics (7 abstracts, 4 for oral
and 3 for text exchange)
Introduction of Mini Symposium O: Mechanism and Pathwayoplosis of Skeletal Adaptation Organized by Prof.
Yi-xian Qin (USA), 2 invited speakers will make keynote lectures
Above two parts combine together as a joint meeting
---------------------------------------------------------------------------------------2 keynote lectures from minisymposium O: Mechanism and Pathwayoplosis of Skeletal Adaptation (every
keynote lecture for 20 minutes including 5 minutes discussion).
(1) Mechanotransduction on Osteoblasts and In Vivo Adaptation for Osteogenic Regulation (101)
Yi-Xian Qin, Shu Zhang, Suzanne Ferreri, Jacky Cheng
(2) Adaptation of nonmuscle cells to mechanical environment (102)
Shinji Deguchi1,2,*, Tsubasa S. Matsui1,3, Masaaki Sato1,4
Oral Session (Delta δ1)
Title: Special topics in mechanobiology (new methods, new techniques, new concepts, new theories（7 oral
presentation, every presentation for 15 minutes including 3 minutes discussion, if time is enough, chairs will
adjust the schedule）
From VII Special topics (3 abstracts for oral)
(3) Quantitative magnetic resonance imaging (MRI) analysis for knee cartilage in the healthy and anterior
cruciate ligament-reconstructed knees (219)
Hong Li, M.D., Yinghui Hua, M.D., Jiwu Chen, M.D., Yunxia Li, M.D., Shiyi Chen, M.D., Ph.D.
(4) Gravity affects the responsiveness of osteoblastto bone related cytokines (220)
Dai Zhongquan, Guo Feima, Wu Feng, Wan Yumin,Li Yinghui
(5) Mechanics and composition of middle cerebral artery of simulated microgravity rats with and without
daily–Gx gravitation (221)
Jiu-Hua Cheng, Fang Gao, Yun-Gang Bai, Li-Fan Zhang
Time: 10:25~10:35
Tea break
- 11 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Time: 10:35~12:30, Am, November 6
Place: Huashia Hall
Special Session T (2)
Cerebration for Honorary Professor Shu Chien’s 80th Birthday
Paper report meeting I: Dedicated to the 80th birthday for honorary Professor Shu Chien
（贺钱煦教授 80 华诞论文报告会 I）(144)
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
Chairs: Prof. Nan-ping Wang and Prof. Shu-sen Liu
Emerging Roles of MicroRNAs in Endothelial Mechanotransduction (145)
Nanping Wang
Mitochondrial Membrane Fusion and ATP Synthesis both Compete for Intersurfacial ∆pHS Component of
PMF, but not ∆Ψ-- The Nature of Link between Mitochondrial Dynamics and Chemiosmotic Bioenergetics
(146)
Liu Shu-sen
Fluidic Shear Stress Induced Morphological Remodeling and Adaptation of Bone Cells in Microfluidics
(147)
Wenfu Zheng, Wei Zhang, Xingyu Jiang
Cell adhesion and differentiation on nano- or micro-patterned surfaces (细胞在微纳米图案化表面
的黏附与分化) (148)
Ce YAN, Rong PENG, Xiang YAO, Xuan WANG, Weiran WANG, Stefan GRAETER, Jian TANG, Peng LIU,
Jinghuan HUANG, Yuxiao LAI, Jianguo SUN, Huan ZHANG, and Jiandong DING (丁建东)
On the way to engineer three-dimensional platform for screening against voltage-gated calcium channels
with neuronal cells (150)
Ze-Zhi Wu, William S. Kisaalita, Li-Guang Zhang, Zheng-Wei Wang, Zhi-Xing An, Man-Gen Zhu1, Lina Wang2,
Yiping Zhao3, Qi-Ping Huang1, Chenzhong Li4
Time: 10:35~12:30, Am, November 6
Place: Room I
Mini Symposium R(2): Multiscale modeling of cellular Mechanobiology & Cell Mechanics (115)
Organizer and Chair: Prof. Xiaobo Gong (China) & Prof. Chwee Teck Lim (Singapore）
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
Effects of Vascular Network on Thermal Ablation of Biological Tissues (121)
B. Li, H. Huang, W. Sun
Dynamic Modeling of TRPV4-mediated Intracellular Calcium Response of Endothelial Cells Induced by
Flow and ATP (118)
Yizeng Li, Kai-Rong QIN
Analysis of ciliary motion and the axonemal structure in the mouse respiratory cilia (119)
HIRONORI UENO, TAKUJI ISHIKAWA, KHANH HUY BUI, KOHSUKE GONDA, TAKASHI ISHIKAWA,
TAKAMI YAMAGUCHI
Particulate-based simulation of myosin-dependent rearrangement dynamics of actomyosin networks (122)
Yasuhiro Inoue, Shunsuke Tsuda, Koji Nakagawa , Masaki Hojo, Taiji Adachi
A Numerical Study on the Mass Transfer over Cell Membranes Based on Immersed Boundary Method (117)
Xiaobo Gong, Huaxiong Huang
- 12 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Time: 10:35~12:30 Pm, November 6
Place: Room II (A)
Mini Symposium K: Mechanobiology of nuclear (79)
Organizer and chair: Prof. G. V. Shivashankar (Singapore)
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust the
schedule)
Spatio-temporal organization of transcription factories within living cells (80)
Shovamayee Maharana, G.V.Shivashankar
Modulating nuclear organization alters segmental gene expression patterns in Drosophila embryos (81)
Abhishek Kumar, G.V.Shivashankar
Probing the functional integration of mechanosignals to chromatin organization in living cells (82)
K.Venkatesan Iyer, G.V.Shivashankar
Time: 10:35~12:30 Pm, November 6
Place: Room III
Session (Alpha α2)
Biophysics and Molecular Biology of force sensing and generation
Chairs: Chairs: Prof. Ming-jer Tang, Prof. Chao-min Cheng, Prof. Chun Yang
Introduction of Session Alpha (α)
20 abstracts from Part A: Basic Mechanobiology (I Biophysics and Molecular Biology of force sensing and
generation), among 20 abstracts, 13 for oral, 5 for poster, and 2 for text exchange.
Oral Session (Alpha α2)
Title: Biophysics and Molecular Biology of force sensing and generation
（13 oral presentations, every presentation for 15 minutes including 3 minutes discussion）
(8) Computer simulation of membrane proteins: Aggregation, signal transduction, and endocytosis (167)
Tongtao Yue and Xianren Zhang
(9) Bending and Puncturing the Influenza Lipid Envelope (169)
Sai Li, Frederic Eghiaian, Christian Sieben, Andreas Herrmann, Iwan A.T. Schaap
(10) HIGH-EFFICIENCY CELLULAR TRACTION FORCE MICROSCOPY (170)
Jianyong Huang, Hao Deng, Shanshan Li, Mingshu Pang, Chunyang Xiong, Jing Fang
(11) Effect of tension on the stiffness of actin filaments (171)
Shinji Matsushita, Yasuhiro Inoue, Masahiro Sokabe, Taiji Adachi
(12) Conformational Entropy Effects on Nanomechanical Behaviors of Microcantilever-Based
Single-Stranded DNA Chips (172)
Neng-Hui Zhang, Zou-Qing Tan, and Jin-Ying Shan
(13) Interaction between Integrin α2β1 and Receptor on Stiff/Soft Substrate (174)
Xiaofei Chen, Jing Du, Quanmei Sun, Chun Yang, Dong Han
- 13 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Poster Session on Biophysics and Molecular Biology of force sensing and generation（5 Poster presentation,
poster board, width 60 cm, height 100 cm)
Coarse-grainedmolecular dynamics simulations of mechano-gating in the E-coli mechanosensitive channel
MscL (161)
Hidetoshi Matsuo, Yasuyuki Sawada, Masahiro Sokabe
Fluid pressure increases the occurrence of spontaneous Ca2+ spark partly via inositol 1,4,5-tripshosphate
receptors in rat ventricular myocytes (162)
Suk-Han Jung, Joon-Chul Kim and Sun-Hee Woo
Non-Gaussian athermal fluctuations in active gels (165)
Toshihiro Toyota, Hayato Sakamoto, Peijuan Zhang, D. Head and Daisuke Mizuno
Nonlinear and anisotropic mechanical response of vimentin network induced by an externally
applied force (173)
E.Ikebe, S.Kinosita, A.Nakamasu, D. Head, P. Zhang and S Ando, D.Mizuno
Low substratum stiffness induces degradation of β1 integrin via reduction of caveolin-1 (175)
Yi-Chun Yeh1, Jin-Ying Ling1, Yang-Kao Wang2, Ming-Jer Tang1
Time: 10:35~12:30Am November 6
Place: Room IV
Mini Symposium A (2): Mechanosensitive Channels and Proteins (18)
Organizers and Chairs: Prof. Boris Martinac and Prof. Yue-zhou Li
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
Mechanism of mechanical regulated Notch activation and structural bases of Notch NRR related T-ALL
(25)
Changjie Lou, Shihua Zhao, Yanqiao Zhang and Jizhong Lou
Transmembrane domain interactions upon MscL gating (26)
Yuezhou Li, Paul Bloun
Sensory and functional interplay of carriers and channels in balancing compatible solute concentration (27)
Kirsten Börngen, Michael Becker, Stanislaw Maksimov, Andrew Battle, Boris Martinac, and Reinhard Krämer
Biophysical mechanism of mechano-gating in bacterial mechanosensitive ion channel MscL: the role of
protein-water interplay (28)
Yasuyuki Sawada and Masahiro Sokabe
High hydrostatic pressure as a tool for studies of bacterial
mechanosensitive channels (29)
Evgeny Petrov, Paul R Rohde, and Boris Martinac
- 14 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Time: 10:35`12:30
Place: Room V
Session (Delta δ2)
Special topics in mechanobiology
Chairs: Prof. Shiyi Chen, Prof. Yi-xian Qin, and Prof. Shinji Duguchi
Oral Session (Delta δ2)
From VIII Other topics in biophysics, mechanobiology, and biomechanics (4 abstracts for oral)
(6) Dual Mechanical Signaling Events Reveal Non-linear Structural Responses (223)
Robert L. Steward Jr., Philip R. LeDuc, Chao-Min Cheng
(7) “Mechanobio-materials”: design of micropatterned elastic gels to control cell mechanotaxis and
motility-related functions (224)
Satoru Kidoaki
(8) CONCENTRATION OF MICRO-ORGANISMS IN MICROFLUIDIC CHANNELS USING
ACOUSTIC RADIATION FORCE (225)
H.P. Lee, M.N. Pham, Y Liu, K.M. Lim, B.C. Khoo, H.T.W. Tan
(9) Stress Analysis of Carotid Atheroma Based on in vivo MRI of Acute Symptomatic Patients (226)
Zhi-Yong Li
Lunch time 12:30~13:30
Place: Jiu Cai Tian Restaurant, Floor 2, Huashia Hotel
Time: 13:30~15:30, Pm, November 6 Lectures of Mini symposia and sessions
Schedule on November 6 Afternoon (13:30~15:30)
English
Names
Nov. 6 PM
13:30~15:25
Huashia Hall
Room I
Room II (A)
Room III
Room IV
Room V
Special
Session T (3)
Session Gamma
(γ1)
Mini Symposium
G(1)
Mini
Symposium L
Session Beta (β1)
Mini Symposium
E (1)
Mini
Symposium
D(1)
Mini
N
Nov. 6 PM
15:35~17:30
Mini
Symposium S
Session Gamma
(γ2)
Mini Symposium
G(2)
Mini
Symposium
D(2)
Mini Symposium P
Symposium
Tea break (15:25-15:35AM)
Mini
Symposium
M
Session Beta (β2)
Mini Symposium
E(2)
Time: 13:30~15:25, Pm, November 6
Place: Huashia Hall
Special Session T (3)
Cerebration for Honorary Professor Shu Chien’s 80th Birthday
Paper report meeting II：Rheology and hemodynamics in life systems (151): Dedicated to the 80th birthday
for honorary Professor Shu Chien（贺钱煦教授 80 华诞论文报告会 II）
(A lecture for 20 minutes including 5 minutes discussion, if the time is enough, the chair may adjust
schedule)
Chairs: Prof. Jimmy K Hsia (USA) and Prof. Giovanna Tomaiuolo (Italy)
- 15 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Measurements of red blood cell membrane rheological properties in vitro (151)
Giovanna Tomaiuolo, Stefano Guido (Article abstract on page 199)
Effect of hemodynamics after hypervelocity ballistic impact to the hind limb of pigs (151)
Bo Zhang, Jianmin Wang (Article abstract on page 200)
FDM analysis for MHD flow of a non-Newtonian fluid for blood in stenosed arteries (151)
D. S. Sankar (Article abstract on page 201)
HYSTERESIS LOOPS IN SOME LIFE SUBSTANCES(151)
Shi Yong-de (Article abstract on page 202)
Time: 13:30~15:25, Pm, November 6
Place: Room I
Session Gamma (γ1)
Chairs: Prof. Ahmed Al-Jumaily (New Zealand), Prof. Shi-yi Chen (China), Prof Shi-xiong Xu
Introduction of Session Gamma (γ): 14 Abstracts from Part B: Applied Mechanobiology, among them 3 ones (for
oral) belong to IV Mechanobiology in medical Physiology; 7 ones (4 ones for oral and 3 ones for poster) belong
to V Mechanobiology of diseases; and 4 ones (3 abstracts for oral and 1 for poster) belong to VI
Mechanobiology of medical treatments (14 abstracts in total, 10 for oral and 4 for poster)
Mini Symposium G(1,2): Respiratory and cardiovascular therapies and diagnostics, has one abstract,
entitled “The Role of Oscillation in Respiratory Therapies (61)” which was organized by Prof. Ahmed
Al-Jumaily (New Zealand)
Above two parts are combined to the joint meeting.
Oral Session (Gamma γ1)
Title: Applied Mechanobiology in medical physiology and pathophysiology（11 oral presentation, Keynote
lecture for 20 minutes including 5 minutes discussion, the other lecture for 15 minutes including 3 minutes
discussion, if the time is enough, chairs will adjust the schedule）
(1) Keynote lecture: Prof. Ahmed Al-Jumaily (New Zealand): “The Role of Oscillation in Respiratory
Therapies (61)”
From IV Mechanobiology in medical Physiology (3 abstracts for oral)
(2) ELECTROSTATICS AND MECHANICS OF THE INTERACTIONS BETWEEN OSTEOBLASTS
AND NANOSTRUCTURED SURFACE OF TITANIUM IMPLANTS (196)
A. Iglič, E. Gongadze, D. Kabaso, Š. Perutkova, U. van Rienen , V. Kralj-Iglič
(3) Simulated weightlessness promotes the differentiation of osteoclast (197)
ZongchengTian, Shengmeng Di, Rong Zhang, Maria Luisa Brandi, Peng Shang
(4) DIAMAGNETIC LEVITATION CHANGES MORPHOLOGY, CYTOSKELETON ARCHITECTURE
AND H2-CALPONIN EXPRESSION IN BONE CELLS (198)
Ai-Rong Qian, Xiang Gao, Wei Zhang, Li-Fang Hu, Peng Shang, Jian-Ping Jin
From V Mechanobiology of diseases (4 abstract for oral)
(5) OxLDL and subendothelial matrix stiffness together regulate neutrophil transmigration via
MLCK-mediated cell contraction (204)
Kimberly M. Stroka, Irena Levitan2, Helim Aranda-Espinoza
(6) Differential adhesion dynamics of homotypic and heterotypic cell aggregates on selectin-coated surfaces
under flow (205)
Yue Geng, Adelaide de Guillebon, and Michael R. King (mike.king@cornell.edu)
- 16 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Time: 13:30~15:25, Pm, November 6
Place: Room II (A)
Mini Symposium L: Cell dynamics—from structural basis to disease mechanisms
Organizer and Chair: Prof. Linhong Deng (China)
Airway smooth muscle cell dynamics in relation to pathogenesis of asthma (84)
Xuemei JIANG, and Jiming XU, Aijing SONG, Jiaoyue LONG, Jun CHEN, Yanling Shi, Linhong DENG
Plasticity of BNIP-2 and Cdc42GAP Homology (BCH) domain in 3G-Signalome during cell morphogenesis,
motility and differentiation (86)
Yiting ZHOU, Anjali GUPTA, Aarthi RAVICHANDRAN, Kenny LIM, Catherine Qiurong PAN and Boon Chuan
LOW
Effects of axial stretch on calcium handling in sarcoplasmic reticulum and mitochondria in cardiac
myocytes (87)
Gentaro Iribe, & Keiji Naruse
Effects of Hypertension on Morphological, Contractile and Mechanical Properties of Rat Aortic Smooth
Muscle Cells (88)
T. Matsumoto, M. Yamamoto, S. Seo, J. Sato, Y. Kato, M. Sato
Time: 13:30~15:25, Pm, November 6
Place: Room III
Session Beta (β1): Basic Mechanobiology in cell levels and physiology
Introduction of Session Beta (β): Basic Mechanobiology in cell levels and physiology. 17 abstracts (12 for
oral, 4 for poster, and 1 for text exchange) belong to the following topics: II Cell Biology of shape, migration,
proliferation and differentiation and III Physiology of specialized mechanoreceptors
Introduction of mini symposium E(1,2): Cell proliferation, growth and death which was organized by Prof. J.
Koropatnick (Canada), it has two abstracts.
Now we combine above 2 parts together.
Oral Session Beta (β1)
Chairs: Prof. J. Koropatnick (Canada),, and Dr. Xin Liang
Title: Mechanobiology in cell levels and physiology （1 keynote lecture and 12 regular oral presentation,
every regular presentation for 15 minutes including 3 minutes discussion, but keynote lecture for 20
minutes including 5 minutes discussion）
keynote lecture: J. Koropatnick: Combining antisende/siRNA and small molecular drugs targeting
thymidylate synthase: a strategy for cancer therapy (51)
J. Koropatnick, C. Di Cresce, J. Flynn, A.A. Pandyra, R. Figueredo, P.J. Ferguson, and T.L. Jason
From II Cell Biology of shape, migration, proliferation and differentiation (8 abstracts)
(1) Effect of Stretch micro-strain on proliferation of human degenerate nucleus pulposus and annular
fibrosus cells (177)
SUN Xiaolei, MA Xinlong, LI Xiulan, YANG Zhao, LI Shuang, ZHANG Yang, GUO Yue.
(2) The Effects of Cyclic Mechanical Stress on human nucleus pulposus cells (178)
Ma Xin-long, Yang Zhao, Sun Xiao-lei, Li Xiu-lan, Zhang Yang
- 17 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
(3) A balance between morphology, cell-cell adhesion, and cell-matrix adhesion regulates endothelial cell
stiffness (179)
Kimberly M. Stroka, Helim Aranda-Espinoza
(4) “Mechanobio-materials”: design of micropatterned elastic gels tocontrol cell mechanotaxis and
motility-related functions (180)
Satoru Kidoaki
(5) BIOLOGICAL EFFECTS OF CELLULAR STRETCH ON HUMAN DERMAL FIBROBLASTS (181)
Chenyu Huang, Kunio Miyazaki, Satoshi Akaishi, Hiko Hyakusoku, and Rei Ogawa
(6) Soft ECM suppresses Wnt/β-catenin pathway: the role in the maintenance of the chondrogenic phenotype
(186)
Jing Du, Yan Zu, Xiaofei Chen, Guangyao Zhang and Chun Yang
Time: 13:30~15:25, Pm, November 6
Place: Room IV
Mini Symposium D(1)：From cytoskeletal systems to the extracellular matrix (39)
Organizer and Chair: Prof. Rommel G. Bacabac, PhD, Philippines.
Email: rgbacabac@gmail.com
High Resolution Probing of Elasticity Using Optical Tweezers: from Molecules to Living Cells (41)
Rommel G. Bacabac, Albert Licup, Heev Ayade, Lara Gay M. Villaruz, Ma. Victoria Carpio-Bernido, Christopher
Bernido, Roland Otadoy
Cell mechanical behaviorin 2D and 3D environments (42)
Baldomero Alonso-Latorre, Karin Jansen, Rommel G. Bacabac, Gijsje H.Koenderink
MECHANOSENSATION BY OSTEOCYTES AND BONE REMODELLING (43)
Jenneke Klein-Nulend
Exploring the Nano-Mechanical Structure of Viruses Using Force Spectroscopy (44)
Gijs Wuite
Effect of Cell-substrate Interactions and Actomyosin Contractility on Lamellipodial Protrusion Dynamics
on a Micro-stamped Surface (45)
Taiji Adachi, Kennedy O. Okeyo, Masuzo Nagasaki, Junko Sunaga, Masaki Hojo, Hidetoshi Korea
Time: 13:30~15:25, Pm, November 6
place: Room V
Mini Symposium N: Mechano-sensing (94)
Organizer and Chair: Prof. Jay X Tang (USA)
Probing mechano-sensing using traction microscopy-Application in neutrophil migration and transendothelial
migration on soft substrate (95)
Jay X Tang,
Mechanosensing during Neutrophil Transmigration (96)
Jose Helim Aranda-Espinoza
Mechano-sensing During Angiogenesis (97)
Joseph P. Califano, John Huynh and Cynthia A. Reinhart-King
A stick-slip model of mesenchymal cell motility (98)
P. Sens
Molecular Organization of the Distal Tip, a Potential Mechanotransduction site, in the Campaniform
- 18 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
receptor of Drosophila melanogaster (99)
Xin Liang, Johnson Madrid, Jonathon Howard*
Teak Break time: 15:25~15:35 pm, November 6
Time: 15:35~17:30 pm, November 6
Place: Huashia Hall
Mini Symposium S: Mechanical Adaptation of Blood Vessels: From Engineered Tissues to
Cells (127)
Organizer and Chair: Prof. Takeo Matsumoto (Japan) & Prof. Guo-qiang Wu, (China)
Hilbert-Huang Transform of Wall Shear Stress Induced by Blood Flow at Rest and after Exercises in
Human Common Carotid Arteries (128)
Kai-Rong QIN
Microscopic mechanical analysis of aortic wall: Heterogeneous mechanical environment in the aortic wall
at the cellular level (129)
Takeo MATSUMOTO
A small diameter elastic blood vessel wall prepared under pulsatile stimulation (130)
Lei CUI
Intracellular strain and change in local mechanical property of vascular smooth muscle cells induced by the
application of static tensile strain (131)
Hiroshi MIYAZAKI
Vascular endothelial cell mechanics induced by blood flow: Mechanical environment inside and outside of
cells (132)
Toshiro OHASHI
Time: 15:35~17:30 pm, November 6
Place: Room I
Session Gamma (γ2)
Chairs: Prof. Ahmed Al-Jumaily (New Zealand), Prof. Shi-yi Chen (China), Prof Shi-xiong Xu
Oral Session (Gamma γ2)
Title: Applied Mechanobiology in medical physiology and pathophysiology（11 oral presentation, Keynote
lecture for 20 minutes including 5 minutes discussion, the other lecture for 15 minutes including 3 minutes
discussion, if the time is enough, chairs will adjust the schedule）
(7) Numerical simulation of avascular tumor growth based on P27 gene regulating (209)
Zhou Yu ，Chen Jiawan，Dai Xiaoning，Cai Yan，Lv Jie，Yao Wei ，Xu Shixiong，Quan Long
(8) The response of cyclic tensile strain on the human degenerative and non-degenerative anulus fibrosus
(AF) cells (210)
Ma xin-long, Li shuang, Sun Xiao-lei, Li Xiu-lan, Zhang Yang, Ma Jian-xiong, Guo Yue, Ning Shang-long
From VI Mechanobiology of medical treatments (3 abstracts for oral)
(9) Decreased Cell Stiffness of Keloid Fibroblast Result in Their Hyper-responsiveness to Mechanical
Stimulation (212)
Chao-Kai Hsu, Hsi-Hui Lin, Yang-Kao Wang, Hans I-Chen Harn, Chao-Min Cheng, Shyh-Jou Shieh, Julia
Yu-Yun Lee, and Ming-Jer Tang
(10) Biological basis for designing collagen scaffold for regenerative medicine (214)
- 19 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Qingsong Ye DDS; PhD; MSc
(11)Computational Hemodynamic Modeling for a Subject-specific Cerebral Aneurysm Treated by
Stent-assisted Coil Embolization (215)
Shengzhang Wang, Xinjian Yang, Xiaolong Zhang
Poster Session on Mechanobiology in medical physiology and pathophysiology（4 Poster presentation,
poster board, width 60 cm, height 100 cm)
Ha-RasV12 induced cancer cell softening facilitate tumor formation (206)
Hsi-Hui Lin, Yu-Wei Chiou, Jing-Yi Liu, Ming-Jer Tang
Exploring cell stiffness in breast cancer cells of different malignancy (207)
Ching-Yi Liu, Yang-Kao Wang, Hsi-Hui Lin, and Ming-Jer Tang
Numerical simulation of the inhibiting effects on solid tumour cells in anti-angiogenic therapy: an
application of coupled mathematical model of angiogenesis with tumour growth (208)
Yan Cai, Shixiong Xu, Quan Long
Mechanobiolgy-Guided Pathological Scars Managements (213)
Chenyu Huang, Satoshi Akaishi, Teruyuki Dohi, Hiko Hyakusoku and Rei Ogawa
Time: 15:35~17:30 pm, November 6
Place: Room II(A)
Mini Symposium M (89)
Regulation of mechanic signals to osteoblast: functions and mechanism (89)
Alternative splicing of genes in mechanocytes responsding to mechanical signals (89)
Organizer and Chair: Prof. Liling Tang（China）
Gene expression profiling via Long SAGE provides a system understanding of mechanotransduction in
osteoblast regulation (90)
Liling Tang，Huan Liu, Qian Yi, Yi Liao, Jianguo Feng
Osteogenesis and vascularization of MGF24E on bone-defect healing in rabbits (91)
Moyuan Deng, Bingbing Zhang, Yuanliang Wang
The Nuclear Localization of MGF Receptor in Osteoblasts under Mechanical Stimulation (92)
Qin Peng, Bingbing Zhang , Juhui Qiu, Yuanliang Wang
Changes of Functional genes expression in osteoblasts treated with mechanical stimulation (93)
Yi Liao, Jianguo Feng, Liling Tang
Time: 15:35~17:30 pm, November 6
Place: Room III
Oral Session Beta (β2)
Chairs: Prof. J. Koropatnick (Canada),, and Dr. Xin Liang
Title: Mechanobiology in cell levels and physiology （Every regular presentation for 15 minutes including 3
minutes discussion, but keynote lecture for 20 minutes including 5 minutes discussion, to leave time for
poster presentation）.
(7) Responses of Fixed Human Sperms to Increased Fluid Shear Stress (187)
Koji Matsuura, Yuka Asano, Yuka Kuroda, Keiji Naruse
- 20 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
(8) The effect of cyclic tensile strain on Schwann cells growth and alteration of gene expression patterns
(188)
LI shuang, MA xin-long, SUN Xiao-lei, LI Xiu-lan2, ZHANG Yang, GUO Yue
From III Physiology of specialized mechanoreceptors (4 abstracts for oral)
(9) Improved Biocompatibility of ePTFE by Ion Beam Implantation (191)
Hiroshi Ujiie, Yoshiaki Suzuki, Rena Ujiie, Hiroshi Toita., and Toshiyuki Tanaka.
(10) The Artificial Sweat for FTS in the Humanoid Finger (192)
Makoto Tomimoto
(11) Expression of TRP Channels in Aortic Baroreceptor Neurons (193)
On Chai LAU, Ching On WONG, Yu Huang, Xiaoqiang YAO
(12) Mechanotransduction in Tooth Pain Sensation (194)
Min Lin, ZhengYuan Luo, BoFeng Bai, Feng Xu, TianJian Lu
Poster Session on Cell Biology of shape, migration, proliferation and differentiation（4 Poster presentation,
poster board, width 60 cm, height 100 cm)
(1) Mechanosensitivity of CFTR in Regulatory Volume Decrease (RVD) in Epithelial Cells (182)
Changyan XIE, Dong WANG, Wei ZHANG, Xu CAO, Yan WANG, and Pingbo HUANG†
(2) Fabrication of microwell patterns for three dimensional growth of C17.2 neural stem cells (183)
Li-Guang Zhang, Ze-Zhi Wu
(3) PLLA microstructures for quasi-three-dimensional cell-based biosensing (184)
Zheng-Wei Wang, Ze-Zhi Wu, Zhi-Xing An, Qi-Ping Huang, Li-Guang Zhang, Mei-Rong Luo
(4) Substratum stiffness regulates switch control of cell proliferation and differentiation in primary cultures
of mice proximal tubular cells (189)
Wan-Chun Chen, Hsi-Hui Lin, Ming-Jer Tang
Time: 15:35~17:30 pm, November 6
Place: Room IV
Mini Symposium D(2)：From cytoskeletal systems to the extracellular matrix (39)
Organizer and Chair: Prof. Rommel G. Bacabac, PhD, Philippines.
Email: rgbacabac@gmail.com
High Resolution Probing of Elasticity Using Optical Tweezers: from Molecules to Living Cells (41)
Rommel G. Bacabac, Albert Licup, Heev Ayade, Lara Gay M. Villaruz, Ma. Victoria Carpio-Bernido, Christopher
Bernido, Roland Otadoy
Cell mechanical behaviorin 2D and 3D environments (42)
Baldomero Alonso-Latorre, Karin Jansen, Rommel G. Bacabac, Gijsje H.Koenderink
Active fluctuations, mechanical integrity and self-organization in cytoskeletal networks (46)
FC MacKintosh
Stretching oligodendrocytes with a vertically operating optical trap (47)
Schanila Nawaz, Paula Sanchez, Sai Li, Mikael Simons, Iwan A. T. Schaap
Matrix Mechanics Matters for Stem Cell Stress Fibers (48)
Florian Rehfeldt
Mechano-sensing and Active Cytoskeleton (49)
Daisuke Mizuno, R. G. Bacabac, D.A. Head and Christoph Schmidt,
- 21 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Time: 15:35~17:30 pm, November 6
Place: Room V
Mini Symposium P: Mechanosensation and biomechanics of the gastrointestinal tract (103)
Organizer and Chair: Prof. Jing-bo Zhao (Mech-Sense, Aalborg Hospital, Aalborg, Denmark)
Biomechanics and Mechanosensitivity of the Gastrointestinal Tract (104)
Hans Gregersen
Afferent Nerve Discharge during Stress Relaxation in Rat Small Intestine (105)
Donghua Liao, Xiao Lu, Anthony J. Kirkup, Wen Jiang, David Grundy, Hans Gregersen
Mechano-sensory properties of hypertrophic intestine following chronic obstruction (106)
Jian Yang, Jingbo Zhao, Pengmin Chen, Toshiya Nakaguchi, David Grundy, Hans Gregersen
Effect of acute ischemia on the biomechanical properties of rat small intestine (107)
Jingbo Zhao, Hans Gregersen
Time: 18:30~21:00, pm, November 6
Place: Giu Tsai Tian Restaurant, Floor 2, Huashia Hotel
Farewell Banquet
Chair: Prof. Ling-hong Deng
General Chair, Prof. Masahiro Sokabe: Closing address
Co-chair, Prof. Shu Chien: Summary for the Conference
November 7 and 8
Our guests will take buses (by the conference tour tickets) to go to Hangzhou. Buses will start on November 7，8：
00 Am, in front of Huashia Hotel Gate. During November 7-8, our guests will stay Hangzhou for two days. On
November 8, about 19:00 Pm, buses will bring our guests returning Huashia Hotel.
Program in Hangzhou
(1) Following buses for sightseeing (Free to join)
November 7, afternoon, sightseeing in Xihu Lake
November 8, morning, sightseeing in Huang Long Dong
November 8, early afternoon, sightseeing Yuchuan or shopping
November 8, late afternoon, eating supper and returning Shanghai
(2) Academic activities in Hangzhou (Free to join)
(a) Hangzhou Satellite Meeting on Cellular Mechanobiology and Diseases (free to join)
Time and date: 13:30~17:30 Pm, November 7, 2011
Place: Zhejiang University, Hangzhou City
Organizer: Prof. Yuezhou Li (Zhejiang University, China)
Invited speakers including Prof. Shu Chien, Prof. Boris Martinac, Prof. Hong Ouyang, Prof. Yuezhou Li,
etc.
(b) Free Talk: Mechanobiology present and in future 5 years (free to join)
Time and date: 19:00~20:30 Pm, November 7, 2011
Place: No 2 meeting room, Floor 20, Golden Nugget Hotel, Hangzhou City
Organizer: Prof. Masahiro Sokabe, Prof. Jimmy K Xia, Prof. Yong-de Shi
- 22 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Conference Information
Registration
The registration desk will set up the lobby of Huashia Hotel on November 4, and afterwards at floor 3 of the same
hotel
November 4, 8:30Am~19:00Pm
November 5, 8:30Am~17:00Pm
November 6, 8:30Am~17:00Pm
If you have completed the advance fees payment, your conference materials waits your pickup at the Conference
Registration Desk.
If you will arrive the Conference Desk before November 4, please to tell us your air-flight time-table, our
conference staff will wait for you at the lobby of Huashia Hotel.
Registration fees
The registration fees is US$520 for regular participants before the deadline (October 1, 2011), or US$570 after the
deadline.
The registration fee for students is US$320 before the deadline (October 1, 2011), or US$370 after the deadline. A
photocopy of the student ID card should be presented for the registration.
Any accompanied family member should pay US$240 before the deadline (October 1, 2011), or US$300 after the
deadline.
Note: The conference will provide all registered participants and accompanier a copy of the abstract book, a gift,
conference reception and farewell banquet, daily meals as well as a ticket for the Hangzhou tour without any extra
charge.
Methods of payment
All payment including registration fees and hotel room fees should pay to:
Shanghai Society of Biophysics, 2011SICBM by the following means:
(1) Bank Transfer:
Account Number: 1001221009008935253
Account Name: Shanghai Society of Biophysics
Bank: the Industrial and Commercial Bank of China, Shanghai Branch, Xu-hui District Sub-branch, International
Department,
022210-Huai-Hai Zhonglu Division, Shanghai, China
Attn: Prof. Shi Yong-de, Secretary General, Shanghai Society of Biophysics, 2011SICBM payment.
Swift address of the bank: ICBKCNBJSHI
Note: When you transfer your payment to the conference bank, you must type the payee as “Shanghai Society of
Biophysics, 2011SICBM” on your sheet, and e-mail the information to Prof. Shi Yong-de by
info@ssbiophysics.com.cn We shall inform you as soon as possible. If you do not get any prompt response from
us, please contact us again via e-mail.
(2) Pay cash or using credit card at the conference registration desk located in the lobby of the hotel during
registration time, on November 4-6, 2011, but registration fees must be paid by cash.
Cancellation and refund
Any cancellation must be notied to the lShanghai Local Committees in writing for a refund of the registration
fees.
Received by October 4, 2011, 80%
- 23 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Received untill October 19, 2011, 50%
Received after October 20, 2011, no refund
You are encouraged to register for the conference as soon as possible. For advance registration, please complet the
preliminary registration form and return it to Shanghai Local Committee by e-mail: info@ssbiophysics.com.cn or
ydshi@ssbiophysics
The advanced registration and the appropriate fees payment is Before October 1, 2011
Shanghai Conference place: Shanghai Huashia Hotel (3 star),
Address: 38 Tsao Bao Road, Xuhui District, Shanghai 200235, China
Tel: 0086-21-64360100
Fax: 0086-21-64333724
During in Shanghai
Hotel room reservation
Shanghai Huashia Hotel (3 star)
Address: 38 Tsao Bao Road, Xuhui District, Shanghai 200235, China
Tel: 0086-21-64360100
Fax: 0086-21-64333724
Room price（includ breakfast）
Standard room, two beds (width 1.2 m), US$80 per night
Big Bed Standard room, one bed (width 2 m), US$90 per night
Suite Room，one bed (width 2 m), US$110 per night
Shanghai Ever-bright International Hotel (4 star)
Address: 66 Tsao Bao Road, Xuhui District, Shanghai 200235, China
Tel: 0086-21-64842500
Fax: 0086-21-6485595
e-mail: hotel@secec.com
web: http://www.ebhotel.com
Room price（including breakfast）
Standard room, two beds (width 1.1 m), US$90 per night
Standard room, one bed (width 1.8 m), US$90 per night
Business room, two beds (width 1.1 m), US$100 per night
Business room, one bed (width 1.8 m), US$100 per night
Suite room, one bed (width 1.8 m), US$150 per night
Note: The Ever-bright Hotel needs at least to pay one night fees before your staying, otherwise it refuses booking
During in Hangzhou
Golden Nugget Hotel, 73 Mo Gan Shan Road, Hangzhou 310005, Zhejiang Province, China
Tel: 0086-571-88389898
Fax:0086-571-88385328
Room price（including breakfast）
Standard room, two beds (width 1.1 m), US$80 per night
Receipt of payment
The receipt will be distributed at the registration deck. If you have completed the payment in advance, please to
tell the local committee how to write the payment item(s), it means that, would you need a total receipt including
- 24 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
registration fees and hotel room fees to gether? or two pieces one for registration fees and the other for hotel room
fees individually?
Certificate of attendance
The local committee will prepare certificates for attendance.
Social activities
The registrated participants are invited to attend the following social activies with the distributing tickets. We hope
such activities will offer the good opportunities to promote friendship and exchange ideas each other.
Welcome reception dinner: 19:00Pm, November 4, Giu Tsai Tian Restaurant, Floor 2, Huahia Hotel
Farewell Banquet: 18:30~21:00, pm, November 6, Giu Tsai Tian Restaurant, Floor 2, Huashia Hotel
November 7-8, Shanghai-Hangzhou sightseeing: Participants will take buses with tickets to go to Hangzhou. Bus
starting time: November 7，8：00 Am, in front of Huashia Hotel gate, On November 8, about PM 7:00, buses will
bring the participants to Huaxia Hotel
Conference Meals
During the conference and Hangzhou sightseeing, conference will arrange the lunches or suppers for our guests to
enjoy with the tickets. During November 5-6, the dining place is at Giu Tsai Tian Restaurant, floor 2, Huashia
Hotel. During in Hangzhou, the dining place will be announced in dual time.
Oral presentation
The conference will set up a special desk for speakers to check their PPT slides with computer and projector, to
avoid any problems during their presentation. An invited plenary lecture will be 45 minute (including 5 minutes
discussion); an invited mini symposium lecture will be 20 minutes (including 5 minute discussion), and a lecture
of session α, β, γ and δ will be 15 minutes (including 3 minutes discussion), but if time is enough, the chairs can
adjust the time schedule, however all the activities should be completed on time, do not affect the next procedures.
Poster Presentation
The conference will prepare enough poster boards (size as width 60 cm, and height 100 cm.) The boards will be
marked with poster author’s names and title, for author to mount his poster. There are 13 posters to be shown. On
Nov 5, they are placed near Huashia Hall, however, they will be presented respectively in following 3 sessions (α,
β and γ), 5 ones in Session α, 4 ones in session β and 4 ones in session γ. The session chairs must leave 5 minutes
time for every poster author to present, and chairs of session α, β and γ will respectively select one as the best
poster whose author will be offered with the best poster prize during the conference.
On November 5 morning, poster authors can find your poster board, and put your poster papers onto the board.
Next day poster authors or our conference staff will bring the poster board to the relevant session meeting room
for authors to make presentation.
Chair persons’ duties
(1) To check attendance of speakers;
(2) To begin the session on time;
(3) To adjust schedule according to real condition;
(4) The chairs of session α, β and γ need to leave time enough for every poster author to present his poster for 5
minutes, and select a best one respectively from session α, β and γ, report to local committee that will make THE
BEST POSTER PRIZE CERTIFICATE to offer the relevant authors.
- 25 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
(5) To write a brief summary of the session (point out the exchange results of this session and the future trends of
the fields), put it into conference information box, or e-mail to Shanghai local committee afterward, or deliver it
on November 7 evening “Free Talk on Mechanobiology present and in future 5 years”..
Instruction to the authors who want official publication for their articles
Aims:
Some of our colleagues not only hope to print a conference book which contains all the collected abstracts, and
distribute to the all participants during the meeting, but also hope the conference local committee officially to
publish the whole text articles after the meeting in 2012. For this reason, we have visited Shanghai Scientific and
Technological Publishing House, which agrees to publish such a book entitled by “Recent Advances in
Mechanobiology”.
How to solve the financial sources: It needs from the following three ways:
(1) Conference surplus: If the conference has some surplus, it will serve the publication;
(2) Supports from Shanghai side: The Conference Shanghai Local Committee will try to apply some grants from
Shanghai Association for Sciences and Technologies;
(3) Payments from authors as following:
(a) For the plenary lecturers, he/she is invited to send an article within 4 pages (with black and white pringting) of
A4, he/she need not pay any fees, (but if the article is over 4 pages, one page needs to pay 75 usd);
(b) For the regular registered participants, his/her article within 4 pages of A4, he/she only needs to pay 75 usd,
(but if the article is over 4 pages, one page needs to pay 75 usd); if any registered participant want to send more
than one article, the other article needs to pay all pages as 75 usd per a page;
(c) If any author wants to print some color pages in his/her article, additionally to pay 150 usd for every two
pages;
(d) If you interest in official publishing your article(s) in such a book, you will not only send the abstract, but send
the whole text as well (which should be written as the style of BIOPHYSICAL JOURNAL that published in USA,
on web you can easily find the style), and check your pages and relevant fees when you make registration;
(e) If you do not interest in officially publishing your articles in such a book, you need not to send the whole text
article and to pay any more fees for it;
(f) Any authors (either the conference participants or not), may send articles to the local committee to apply for
publication by the payment as a page (A4) for 75 usd;
(g) In order to guarantee the article quality, the article drafts will be evaluated by two members of the Conference
International Advisory Committee, if they said OK, the local committee will confirm to publish the article. If they
said not OK, the payment will return the relevant author(s).
How to receive your article and solve payment
(1) During the conference (November 4, 5 and 6): The local committee will set a special desk to receive articles
and payments (Participants please keep well your invoices of conference and show it to our staff, and check article
pages and payments)
(2) After the conference: Contact to the following person and address:
Prof. Yong-de Shi
Secretary General, Shanghai Society of Biophysics,
Department of Biophysics,
Fudan University, Shanghai Medical College,
200032, Shanghai, China
E-mail: info@ssbiophysics.com.cn
or ydshi@ssbiophysics.com.cn
TEL & FAX 0086-21-64275720
MP: 13701622730
After acceptance and publication
- 26 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
(1) After acceptance: To send the correspondent author with an electronic edition article;
(2) After publication of the book: To send the correspondent author with a copy of the book and 20 copies of article;
(3) To distribute and sale the copies of the books as best as possible, the income belongs to local committee
(4) The rest of the book copies serve the participants of next conference on mechanobiology
Transportation from air-port
Pudong International air-port and Hongqiao International Air-port
Shanghai is the only city in China which has above two international air-ports. Therefore, please pay attention to
which air-port your plan will land on.
How to reach the conference site
From Pudong Air-port: take a taxi (about 40 minutes) to Huashia Hotel, the price is about 160 yuan RMB.
From Hongqiao Air-port: take a taxi (about 20 minutes) to Huashia Hotel, the price is about 40 yuan RMB.
If a taxi driver does not use distance meter or you find the price is too high, you can refuse to pay or write down
the car number and name of the company. The taxi company we recommend is DAZHONG, QIANGSHENG,
JINJIANG, HAIBO etc. After paying, please ask a receipt, on which you can contact the company by the address
and the telephone number on it if you have any problem happening.
Internet Access
For those who stay in Huashia Hotel room, they can use their own notebook computer in their room free charge.
The business center of Huashia Hotel will give the service by price as 10 yuan for 10 minutes, or 20 yuan for 30
minutes.
Conference web site: www.ssbiophysics.com.cn/2011SICBM
Currency
The Chinese currency use a decimal system. Notes come in denominations of RMB 100, 50, 20, 10, 5, 2, 1 yuan
and coins 1, 5 jiao and 1 yuan. Banks are often from 9:00 Am till 16:00 Pm. Traveler’s checks in forein currencies
will be cashed by banks and hotels but not be acceped in shops. The exchange rate is subject to market
fluctuations. One US dollar at present may be between 6.4-6.5 yuan RMB.
Credit cards
Credit cards, including VISA, American Express, Diners Club, Master Card and JBC, are accepted at major hotels,
department stores, and the large restaurants. However, the organizer, Shanghai Society of Biophysics can not
accept credit card.
Electricity
In China, outlets are only for 220 volts.
Passport and Visa
Foreigners whishing to enter the People’s Republic of China should have a valid passport. Visitors should obtain
entry visa before coming in, The invitation letter we mailed you, is the important document for you to apply visa.
Climate
Shanghai and Hangzhou has a mild climate. November is in the late of Autumn and the weather begins to cold,
but the sun remains warm during the daytime. The average temperature is about 15 degree centigrade during the
day, dropping to 10 degree centigrade at night. Most of the time, it is fine or cloudy, but some time is is raining.
Time difference
China is earlier a day than America and Europe, please do not calculate the day wrong for your arriving Shanghai.
- 27 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Explanation for 4 Sessions:Alpha (α). Beta (β), Gamma (γ), and Delta (δ)
Authors sending abstracts according to conference outline which can be divided into following four
sessions as shown by Alpha (α). Beta (β), Gamma (γ), and Delta (δ):
Session (Alpha α)
Title and contents: Biophysics and Molecular Biology of force sensing and generation (20 abstracts)
Session (Beta β)
Title and contents: Mechanobiology of cells and physiology (17 abstracts)
Session (Gamma γ)
Title and contents: Applied Mechanobiology in medical physiology and pathophysiology（14
abstracts）
Session (Delta δ)
Title and contents: Special topics in mechanobiology (new methods, new techniques, new concepts,
new theories, etc（12 abstracts）
- 28 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Session (Alpha α)
Abstracts from Part A: Basic Mechanobiology
I Biophysics and Molecular Biology of force sensing and generation (20 abstracts, 13 for oral,
5 for poster, and 2 for text exchange)
Oral Session (Alpha α)
Title: Biophysics and Molecular Biology of force sensing and generation
（13 oral presentations, lasting half a day, every presentation for 15 minutes including 3 minutes
discussion）
Chairs: Prof. Ming-jer Tang, Prof. Chao-min Cheng, Prof. Chun Yang
Date and time:
Place:
Duties: to finish all lectures on time, to finish all poster show, and to make a summary in these fields and future
(1) Biophysical Linkage between Local Mechanical Properties and Global Cellular Responses in Living
Fibroblasts: Actin Cytoskeleton Perspectives(156)
Hans I-Chen Harn, Yang-Kao Wang, Hsi-Hui Lin, Chao-Min Cheng, Ming-Jer Tang
(2) Interaction of the Antimicrobial Peptide NK-2 with Phospholipid Membranes (157)
Sanat Karmakar, Reinhard Lipowsky, Rumiana Dimova
(3) Sensing Substrate Rigidity by Mechanosensitive Ion Channels with Stress Fibers and Focal Adhesions
(158)
Takeshi Kobayashi, Masahiro Sokabe
(4) Regulation of Focal Adhesion Kinase through Syndecan-4 under Mechanical Stimulation (159)
Robert L. Steward Jr, Robert M. Bellin, Philip R. LeDuc, Chao-Min Cheng
(5) Fluid flow stress influences distribution and expression of polycystin1/2 in MLO-Y4 and MC3T3-E1
cells (163)
Jian Zhang, Hui-yun Xu, Jia-wei Wu, Peng Shang
(6) Fibronectin is involved in gravity-sensing of osteoblast like cell (164)
Jingbao Li, Yanan Li, Liang Wang, Mingzhi Luo, Airong Qian and Peng Shang
(7) THE INFLUENCE OF PHYSICAL AND PHYSIOLOGICAL CUES ON ATOMIC FORCE
MICROSCOPPY ASSESSMENT TO CELL (166)
Yu-Wei Chiou, Hsi-Hui Lin, Ming-Jer Tang, Ming-Long Yeh
(8) Computer simulation of membrane proteins: Aggregation, signal transduction, and endocytosis (167)
Tongtao Yue and Xianren Zhang
(9) Bending and Puncturing the Influenza Lipid Envelope (169)
Sai Li, Frederic Eghiaian, Christian Sieben, Andreas Herrmann, Iwan A.T. Schaap
(10) HIGH-EFFICIENCY CELLULAR TRACTION FORCE MICROSCOPY (170)
Jianyong Huang, Hao Deng, Shanshan Li, Mingshu Pang, Chunyang Xiong, Jing Fang
- 29 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
(11) Effect of tension on the stiffness of actin filaments (171)
Shinji Matsushita, Yasuhiro Inoue, Masahiro Sokabe, Taiji Adachi
(12) Conformational Entropy Effects on Nanomechanical Behaviors of Microcantilever-Based
Single-Stranded DNA Chips (172)
Neng-Hui Zhang, Zou-Qing Tan, and Jin-Ying Shan
(13) Interaction between Integrin α2β1 and Receptor on Stiff/Soft Substrate (174)
Xiaofei Chen, Jing Du, Quanmei Sun, Chun Yang, Dong Han
Poster Session on Biophysics and Molecular Biology of force sensing and generation（5 Poster
presentation, poster board, width 60 cm, height 100 cm)
Coarse-grainedmolecular dynamics simulations of mechano-gating in the E-coli mechanosensitive channel
MscL (161)
Hidetoshi Matsuo, Yasuyuki Sawada, Masahiro Sokabe
Fluid pressure increases the occurrence of spontaneous Ca2+ spark partly via inositol 1,4,5-tripshosphate
receptors in rat ventricular myocytes (162)
Suk-Han Jung, Joon-Chul Kim and Sun-Hee Woo
Non-Gaussian athermal fluctuations in active gels (165)
Toshihiro Toyota, Hayato Sakamoto, Peijuan Zhang, D. Head and Daisuke Mizuno
Nonlinear and anisotropic mechanical response of vimentin network induced by an externally
applied force (173)
E.Ikebe, S.Kinosita, A.Nakamasu, D. Head, P. Zhang and S Ando, D.Mizuno
Low substratum stiffness induces degradation of β1 integrin via reduction of caveolin-1 (175)
Yi-Chun Yeh1, Jin-Ying Ling1, Yang-Kao Wang2, Ming-Jer Tang1
Following 2 abstracts for text exchange
MEMBRANE TENSION AND CYTOPLASMIC CROWDING PRESSURE: THE MULTIMODAL
MECHANISM OF THE MECHANOSENSITIVE CHANNEL MscS (160)
Andriy Anishkin, Kenjiro Yoshimura, Kishore Kamaraju, Vladislav Belyy and Sergei Sukharev
The status of platelet membrane actin and its interaction with other components (168)
Zhuang QQ;. Stracher A
- 30 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Session (Beta β)
Abstracts from Part A: Basic Mechanobiology
II Cell Biology of shape, migration, proliferation and differentiation
III Physiology of specialized mechanoreceptors
(17 abstracts, 12 for oral, 4 for poster, and 1 for text exchange)
Oral Session (Beta β)
Title: Mechanobiology in cells and physiology（12 oral presentation, lasting half a day, every presentation
for 15 minutes including 3 minutes discussion）
From II Cell Biology of shape, migration, proliferation and differentiation (8 abstracts)
(1) Effect of Stretch micro-strain on proliferation of human degenerate nucleus pulposus and annular
fibrosus cells (177)
SUN Xiaolei, MA Xinlong, LI Xiulan, YANG Zhao, LI Shuang, ZHANG Yang, GUO Yue.
(2) The Effects of Cyclic Mechanical Stress on human nucleus pulposus cells (178)
Ma Xin-long, Yang Zhao, Sun Xiao-lei, Li Xiu-lan, Zhang Yang
(3) A balance between morphology, cell-cell adhesion, and cell-matrix adhesion regulates endothelial cell
stiffness (179)
Kimberly M. Stroka, Helim Aranda-Espinoza
(4) “Mechanobio-materials”: design of micropatterned elastic gels tocontrol cell mechanotaxis and
motility-related functions (180)
Satoru Kidoaki
(5) BIOLOGICAL EFFECTS OF CELLULAR STRETCH ON HUMAN DERMAL FIBROBLASTS (181)
Chenyu Huang, Kunio Miyazaki, Satoshi Akaishi, Hiko Hyakusoku, and Rei Ogawa
(6) Soft ECM suppresses Wnt/β-catenin pathway: the role in the maintenance of the chondrogenic phenotype
(186)
Jing Du, Yan Zu, Xiaofei Chen, Guangyao Zhang and Chun Yang
(7) Responses of Fixed Human Sperms to Increased Fluid Shear Stress (187)
Koji Matsuura, Yuka Asano, Yuka Kuroda, Keiji Naruse
(8) The effect of cyclic tensile strain on Schwann cells growth and alteration of gene expression patterns
(188)
LI shuang, MA xin-long, SUN Xiao-lei, LI Xiu-lan2, ZHANG Yang, GUO Yue
From III Physiology of specialized mechanoreceptors (4 abstracts for oral)
(9) Improved Biocompatibility of ePTFE by Ion Beam Implantation (191)
Hiroshi Ujiie, Yoshiaki Suzuki, Rena Ujiie, Hiroshi Toita., and Toshiyuki Tanaka.
(10) The Artificial Sweat for FTS in the Humanoid Fingertip (192)
Makoto Tomimoto
(11) Expression of TRP Channels in Aortic Baroreceptor Neurons (193)
On Chai LAU, Ching On WONG, Yu Huang, Xiaoqiang YAO
(12) Mechanotransduction in Tooth Pain Sensation (194)
Min Lin, ZhengYuan Luo, BoFeng Bai, Feng Xu, TianJian Lu
Poster Session on Cell Biology of shape, migration, proliferation and differentiation（4 Poster presentation,
poster board, width 60 cm, height 100 cm)
(1) Mechanosensitivity of CFTR in Regulatory Volume Decrease (RVD) in Epithelial Cells (182)
Changyan XIE, Dong WANG, Wei ZHANG, Xu CAO, Yan WANG, and Pingbo HUANG†
- 31 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
(2) Fabrication of microwell patterns for three dimensional growth of C17.2 neural stem cells (183)
Li-Guang Zhang, Ze-Zhi Wu
(3) PLLA microstructures for quasi-three-dimensional cell-based biosensing (184)
Zheng-Wei Wang, Ze-Zhi Wu, Zhi-Xing An, Qi-Ping Huang, Li-Guang Zhang, Mei-Rong Luo
(4) Substratum stiffness regulates switch control of cell proliferation and differentiation in primary
cultures of mice proximal tubular cells (189)
Wan-Chun Chen, Hsi-Hui Lin, Ming-Jer Tang
Following 1 abstract only for text exchange
Shear stress triggered an increase in [Ca2+]i through Ca2+ influx by activating a TRPV4-like channel in rat
synoviocytes (185)
Fen Hu, Jiahui Yang, Yonglin Sun, Dan Zhao, Shuang Yang, Junying Li
- 32 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Session (Gamma γ)
Abstracts from Part B: Applied Mechanobiology
IV Mechanobiology in medical Physiology (3 abstracts for oral)
V Mechanobiology of diseases (4 abstract for oral and 3 ones for poster)
VI Mechanobiology of medical treatments (3 abstracts for oral and 1 for poster)
(14 abstracts in total, 10 for oral and 4 for poster)
Oral Session (Gamma γ)
Title: Applied Mechanobiology in medical physiology and pathophysiology（10 oral
presentation, lasting half a day, every presentation for 15 minutes including 3 minutes
discussion）
From IV Mechanobiology in medical Physiology (3 abstracts for oral)
(1) ELECTROSTATICS AND MECHANICS OF THE INTERACTIONS BETWEEN OSTEOBLASTS
AND NANOSTRUCTURED SURFACE OF TITANIUM IMPLANTS (196)
A. Iglič, E. Gongadze, D. Kabaso, Š. Perutkova, U. van Rienen , V. Kralj-Iglič
(2) Simulated weightlessness promotes the differentiation of osteoclast (197)
ZongchengTian, Shengmeng Di, Rong Zhang, Maria Luisa Brandi, Peng Shang
(3) DIAMAGNETIC LEVITATION CHANGES MORPHOLOGY, CYTOSKELETON ARCHITECTURE
AND H2-CALPONIN EXPRESSION IN BONE CELLS (198)
Ai-Rong Qian, Xiang Gao, Wei Zhang, Li-Fang Hu, Peng Shang, Jian-Ping Jin
From V Mechanobiology of diseases (4 abstract for oral)
(4) OxLDL and subendothelial matrix stiffness together regulate neutrophil transmigration via
MLCK-mediated cell contraction (204)
Kimberly M. Stroka, Irena Levitan2, Helim Aranda-Espinoza
(5) Differential adhesion dynamics of homotypic and heterotypic cell aggregates on selectin-coated surfaces
under flow (205)
Yue Geng, Adelaide de Guillebon, and Michael R. King (mike.king@cornell.edu)
(6) Numerical simulation of avascular tumor growth based on P27 gene regulating (209)
Zhou Yu ，Chen Jiawan，Dai Xiaoning，Cai Yan，Lv Jie，Yao Wei ，Xu Shixiong，Quan Long
(7) The response of cyclic tensile strain on the human degenerative and non-degenerative anulus fibrosus
(AF) cells (210)
Ma xin-long, Li shuang, Sun Xiao-lei, Li Xiu-lan, Zhang Yang, Ma Jian-xiong, Guo Yue, Ning Shang-long
From VI Mechanobiology of medical treatments (3 abstracts for oral)
(8) Decreased Cell Stiffness of Keloid Fibroblast Result in Their Hyper-responsiveness to Mechanical
Stimulation (212)
Chao-Kai Hsu, Hsi-Hui Lin, Yang-Kao Wang, Hans I-Chen Harn, Chao-Min Cheng, Shyh-Jou Shieh, Julia
Yu-Yun Lee, and Ming-Jer Tang
(9) Biological basis for designing collagen scaffold for regenerative medicine (214)
Qingsong Ye DDS; PhD; MSc
(10)Computational Hemodynamic Modeling for a Subject-specific Cerebral Aneurysm Treated by
Stent-assisted Coil Embolization (215)
Shengzhang Wang, Xinjian Yang, Xiaolong Zhang
- 33 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Poster Session on Mechanobiology in medical physiology and pathophysiology（4 Poster
presentation, poster board, width 60 cm, height 100 cm)
Ha-RasV12 induced cancer cell softening facilitate tumor formation (206)
Hsi-Hui Lin, Yu-Wei Chiou, Jing-Yi Liu, Ming-Jer Tang
Exploring cell stiffness in breast cancer cells of different malignancy (207)
Ching-Yi Liu, Yang-Kao Wang, Hsi-Hui Lin, and Ming-Jer Tang
Numerical simulation of the inhibiting effects on solid tumour cells in anti-angiogenic therapy: an
application of coupled mathematical model of angiogenesis with tumour growth (208)
Yan Cai, Shixiong Xu, Quan Long
Mechanobiolgy-Guided Pathological Scars Managements (213)
Chenyu Huang, Satoshi Akaishi, Teruyuki Dohi, Hiko Hyakusoku and Rei Ogawa
- 34 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Session (Delta δ)
Abstracts from Part C: Special topics in mechanobiology (12 abstracts, 7 for oral and 5 for text exchange)
VII Special topics (5 abstracts, 3 for oral and 2 for text exchange)
VIII Other topics in biophysics, mechanobiology, and biomechanics (7 abstracts, 4 for oral and 3 for text
exchange)
Oral Session (Delta δ)
Title: Special topics in mechanobiology (new methods, new techniques, new concepts, new theories（7 oral
presentation, lasting half a day, every presentation for 15 minutes including 3 minutes discussion）
From VII Special topics (3 abstracts for oral)
(1) Quantitative magnetic resonance imaging (MRI) analysis for knee cartilage in the healthy and anterior
cruciate ligament-reconstructed knees (219)
Hong Li, M.D., Yinghui Hua, M.D., Jiwu Chen, M.D., Yunxia Li, M.D., Shiyi Chen, M.D., Ph.D.
(2) Gravity affects the responsiveness of osteoblastto bone related cytokines (220)
Dai Zhongquan, Guo Feima, Wu Feng, Wan Yumin,Li Yinghui
(3) Mechanics and composition of middle cerebral artery of simulated microgravity rats with and without
daily–Gx gravitation (221)
Jiu-Hua Cheng, Fang Gao, Yun-Gang Bai, Li-Fan Zhang
From VIII Other topics in biophysics, mechanobiology, and biomechanics (4 abstracts for oral)
(4) Dual Mechanical Signaling Events Reveal Non-linear Structural Responses (223)
Robert L. Steward Jr., Philip R. LeDuc, Chao-Min Cheng
(5) “Mechanobio-materials”: design of micropatterned elastic gels to control cell mechanotaxis and
motility-related functions (224)
Satoru Kidoaki
(6) CONCENTRATION OF MICRO-ORGANISMS IN MICROFLUIDIC CHANNELS USING
ACOUSTIC RADIATION FORCE (225)
H.P. Lee, M.N. Pham, Y Liu, K.M. Lim, B.C. Khoo, H.T.W. Tan
(7) Stress Analysis of Carotid Atheroma Based on in vivo MRI of Acute Symptomatic Patients (226)
Zhi-Yong Li
Following 4 abstracts or articles for text exchange
A new explanation for movement of plant Mimosa pudica by stress-shear hysteresis loop (218)
SHI Yong-De, PAN Luan-Feng, YANG Fei-Kun, ARTMANN Gerhard Michael
Reasons why mechanobiology uprising in China during last century (227)
Yong-de Shi
INVESTIGATION ON PUBLICATION NUMBER IN MECHNOBIOLOGY FIELDS (229)
(Local Preparation Committee for 5th SICBM)
Acknowledgement from Local Committee (238)
Prof. Yong-de Shi，Secretary General, Shanghai Society and 5th SICBM
- 35 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
Proposal: Free talk on Mechanobiology present and in future 5 years (asking to
write on paper and put into conference information box, or e-mail to
Shanghai Local Committee by info@ssbiophysics.com.cn or
ydshi@ssbiophysics.com.cn) or to deliver on “Free talk” meeting
on November 7, 19:00~20:30 Pm, No 2 meeting room, Floor 20,
Golden Nugget Hotel, Hangzhou City).
Please to write your proposal below:
- 36 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
- 37 -
International Symposium on Mechanobiology (5TH SICBM), November 4-8, Shanghai, China
- 38 -