BIO 10 Take-Home Assignment #5 KEY Fall, 2007 1. AABbcc will produce equal proportions of ABc and Abc gametes. AaBBCc will produce equal proportions of ABC, aBC, ABc, and aBc gametes. AaBbCc will produce equal proportions of ABC, abc, Abc, aBC, aBc, AbC, abC, and ABc gametes. 2. Both parents are Hh. Each will produce ½ H and ½ h gametes. H h H HH Hh h Hh hh Answer: ¾ H_ (hornless); ¼ hh (horned) 3. A child’s sex is inherited independently from whether or not her/she is a taster. Probability of tasters from the cross: T t T TT Tt t Tt tt = ¾ (T_) tasters; ¼ (tt) non-tasters Probability of having a boy is ½; Probability of having a girl is ½ Answer: 4. Probability child is a non-taster girl = (1/4)(1/2) = 1/8 Probability child is a taster boy = (3/4)(1/2) = 3/8 The alleles at each gene locus are inherited independently (Mendel’s Law of Independent Assortment): EeBbWW x EeBbww (1/4)(1/4)(1) = 1/16 eebbW_ eeBBWw x EebbWw (1/2)(0)(3/4) = 0 chance of eebbW_ 5a. ssRR x SSR’R’ All offspring SsRR’ = straight-haired roans 5b. SsRR’ x ssRR’ sR sR’ Answer: 6. 1 1 2 2 1 1 SR SsRR SsRR’ SsRR ssRR SsRR’ ssRR’ SsR’R’ ssR’R’ sR ssRR ssRR’ SR’ SsRR’ SsR’R’ sR’ ssRR’ ssR’R’ straight-haired red curly-haired red straight-haired roan curly-haired roan straight-haired white curly-haired white First determine as much as possible about the genotypes of the parents and the offspring from their phenotypes: S_B_ male x S_bb female Offspring include 2 S_B_, 2 S_bb, 1 ssB_, and 1 ssbb Since there are offspring that are ss, both parents must be Ss. Since there are offspring that are bb, the male parent must be bb. Answer: Male parent is SsBb and the female parent is Ssbb. 7. The cross is XcY x XcXC X XC c Xc XcXc XcXC Y XcY XCY Answer: 1 black female, 1 black male, 1 orange male, one tortie female. 8. The man must be bb since he has blue-eyes. His wife must be Bb since her father had blue eyes and therefore had to give her a “b” allele. b B Bb b bb Answer: Half the children would have blue eyes (bb). 9. The question here is whether the man is Bb or BB. Answer: If the man is Bb, each child has a ½ chance of having brown eyes. The chance that all 10 children would have brown eyes is (1/2)10 = 1 in 1,024 since each pregnancy is an independent event. Therefore, it is highly improbable that the man is Bb, but we cannot be completely certain. (There is a 1 in 1024 chance that he is!) After another brown-eyed child, the chance is lowered to 1 in 2048 – but not to zero. 10. bb B_ B_ bb B_ 11. B_ bb There is one gene controlling the trait and three phenotypes, one of which is intermediate between the other two. This is indicative of incomplete dominance. No tails: TT; short tails: TT’; long tails: T’T’ If two short tailed cats are crossed: T T’ T TT TT’ T’ TT’ T’T’ Prediction: 1 no tail: 2 short-tail: 1 long tail. This is roughly consistent with the results that were observed: 1.5 no tail: 2 short tail: 1 long tail A larger sample size would be needed to test the hypothesis with scientific rigor. 12. vv,hh x VV,HH vh VH Vv,Hh All offspring would be Vv,Hh and would therefore have normal wings and a hairless (normal) body. 13. U = white belt; u = uniform coloring F = fused hooves; f = normal hooves uu,ff x UU,FF As in question 12, all offspring will be the same. In this case, they will all be Uu,Ff (white belt, fused hooves) Uu,Ff x Uu,Ff We know from Mendel’s Second Law that when two dihybrids are mated, the offspring will fall into the following phenotypic categories: 9 3 U_F_ uniform coloring, fused hooves uuF_ white belt, fused hooves 3 1 14. U_ff uuff uniform coloring, normal hooves white belt, normal hooves G = green; g = striped S = short; s = long gg,ss x Gg,Ss gs Answer: 15. 1 1 1 1 GS SsRR Gs ssRR gS SsRR’ gs ssRR’ green, short green, long striped, short striped, long A_,rr = yellow aa,R_ = black A_R_ = gray Aarr = cream A_R_ x A_rr Offspring: 3/8 A_R_ 3/8 A_rr 1/8 aarr 1/8 aaR_ (gray) (yellow) (cream) (black) Answer: Since there are offspring that are aa, both parents must be Aa. Since there are offspring that are rr, the gray parent must be Rr. Therefore, the parents are AaRr and Aarr. 16. A_rr x aaR_ Offspring: 46 A_R_ (gray) 53 A_rr (yellow) Answer: Since all the offspring have at least one A allele, which must have come from the yellow male parent, it is highly probable that the yellow male parent is AArr. However, there is a slight possibility that he is Aarr and simply failed to pass this along to any of his offspring. To be mathematically precise, there are 99 offspring, all of which inherited the “A” allele from their father. If the father was Aa, the probability of this would be (1/2)99 = 6.23 x 1029!! – HIGHLY improbable indeed! On the other hand, since there are rr offspring, the female parent must be Rr. So the father is (almost certainly) AArr and the mother must be aaRr. 17. C_I_ C_ii ccIi ccii = white = colored = white = white Answer: The cross is Ccii (colored cock) x ccii (white female) How do we know that the white female is ccii? The question states that all the offspring are colored. The only way for this to happen is if the white female parent does not have an “I” allele, and the only possible genotype that gives a white hen that does not have an “I” allele is ccii. Since there are no ccii offspring (which would be white), the cock must be Ccii. 18. K = hearing; k = deaf M = deaf, regardless of genotype at K locus. kkMm x KKmm Km kM KkMm km Kkmm Answer: Half of the offspring will have the genotype KkMm and be deaf because they have a copy of the M allele. Half the offspring will be hearing because they have a K allele and lack an M allele. 19. Xb is a recessive lethal allele. Xb,XB x XB,Y X XB b XB X Xb XB XB B Y Xb Y XB Y Note that the shaded offspring will be dead and not counted among the living offspring of the cross. Answer: The ratio will be 2/3 females to 1/3 males among living offspring. 20. Mrs. Smith: B_ Mr. Smith: A_ Shirley: OO Mrs. Jones: A_ Mr. Jones: A_ Jane: B_ Answer: Yes. Either couple could have produced Shirley, but the Jones’ could not have produced Jane. On the other hand, the Smith’s could have produced Jane. Therefore, a mix-up is consistent with the evidence. 21. The cross data is most consistent with the H allele causing hairlessness and also being lethal in the homozygous state (HH). Hh (hairless) x hh (hairy) yields ½ Hh (hairless) and ½ hh (hairy). Note that since HH is lethal, the hairless dog in this cross must be heterozygous (or it would be dead!). H h H HH Hh h Hh hh This is also consistent with the results when two hairless dogs are mated (Hh x Hh). The HH offspring are dead, leaving 2/3 living hairless and 1/3 living hairy pups. 22. X Xc c XC XC Xc XC Xc Y Xc Y Xc Y Answer: Since all the males inherit their single X chromosome from their mother, and the mother must be homozygous for the mutation since she is affected, they are all colorblind. The daughters inherit one “bad” X from Mom and one normal X from Dad, so are all unaffected carriers. 23. Yes. In order for the girl to be colorblind, she would need a carrier (or affected) mother as well as an affected father. Since her father is not affected, this raises serious doubt to paternity. However, it should be noted that there is a SMALL probability that he father could be an unaffected male whose sperm underwent a spontaneous, new mutation during its production. If this mutant sperm fertilized an egg carrying a mutant X from the mother, the girl would be colorblind.