Department of Anaesthesia & Intensive Care The Chinese University of Hong Kong Prince of Wales Hospital, Shatin ACUTE PAIN SERVICE GUIDELINES & PROTOCOLS 3rd edition 2004 apsguide/3/04 1 INDEX Page 1. Introduction 3 2. Arranging APS service for OT patients 4 3. Arranging APS service for ICU patients 7 4. Requesting for APS service for patients in the general ward 9 5. Recovery room pain relief protocol 10 6. Setting up intravenous patient-controlled analgesia 12 7. Setting up patient-controlled epidural analgesia 15 8. Setting up for continuous epidural infusion analgesia 16 9. Duties of the daytime pain MO 18 10. Duties of the pain nurse 27 11. Acute pain service for the night Obstetric / Pain MO 30 12. Pain MO Guidelines for managing patients with APS devices 31 13. Guidelines on Co-analgesia 37 14. Paediatric pain relief 40 15. Forms and stamps for the acute pain service 43 16. Graseby 3300 pump 46 17. Graseby 9300 pump 54 18. Abbott Pain Manager APM-II pump 60 19. Non-axial regional analgesia 65 20. Private patients’ fee 67 21. Nursing Guidelines – Recovery room pain relief 68 22. Nursing Guidelines – Care of patients on Patient-Controlled Analgesia (PCA) 71 23. Nursing Guidelines – Care of patients on epidural infusion analgesia 74 24. Nursing Guidelines – Monitoring & side effects 77 25. Nursing Standing Orders 79 26. Useful telephone & pager numbers 81 First compiled January 1997 (Authors: PP Chen, M Ma, V Yeo) Revised February 1998 (Authors: PP Chen, M Ma) Revised August 2004 (Authors: MC Chu, J Chen) Acute Pain Service, Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong Prince of Wales Hospital, Shatin, Hong Kong apsguide/3/04 2 INTRODUCTION The Department of Anaesthesia and Intensive Care at the Prince of Wales Hospital provides a 24 hour acute pain service. At present, the modalities of pain relief available are: 1. intravenous patient-controlled analgesia (PCA) 2. patient-controlled epidural analgesia (PCEA) 3. continuous epidural infusion analgesia (CEI) 4. continuous regional analgesia e.g. brachial plexus analgesia, para-vertebral analgesia This book compiles the series of guidelines and protocols produced by the acute pain team which aimed to facilitate the smooth and safe operation of this service. This series will be regularly updated as appropriate, and new guidelines and protocols added as necessary. If you have any query or comment, please contact any of us for further discussion. We shall appreciate your valuable feedback. Acute pain services (APS) team Ms. Marlene Ma / Ms. Wendy Fung / Ms. Josephine Chen (Pain Nurse, DECT phone 6172) Dr. Simon Chan Dr. MC Chu Pain MO (Pager 1067) apsguide/3/04 3 ARRANGING APS SERVICE FOR OT PATIENTS What the anesthesiologist should do Pre-operative 1. All analgesics work best when patients understand and are capable to use it. Please select according to patient’s physical and cognitive state. 2. Explain to patient about the use of PCA pump or epidural analgesia method during your preoperative visit. Informed consent, documentation and communication with parent team doctors and ward staff are recommended. The pain nurse may also assist in preoperative education if the case is not the first on the OT list. Please tick the appropriate box in the request form. 3. Elective cases: fill in the particulars on the request form no later than 0800 on the OT day. Forms are available next to the OT lists at the 5th floor Conference Room, or at the OT control desk. Emergency cases / late elective requests: Inform APS team (pager 1067 / DECT phone 6172) directly. The APS team will try to entertain all requests. Please do not start any APS modalities without discussing with the team. Intra-operative 1. Confirm pump availability with the recovery room after 0830. The APS team will approach you directly in case of problems. 2. Set the pumps and write up the appropriate forms (see below) and keep them with the patient in the OT and the recovery room. Post-operative 1. Optimize analgesia with adequate loading doses before discharging patients from recovery room. 2. Make sure that patient is stable and the APS modality is working before discharging patients from the recovery room. 3. These recommendations are designed to suit the local caseload and the general ward setting. Please inform the APS team in case the anesthesiologist requests for any special analgesic regimes outside the recommendations. The APS team will liaise with the anesthesiologist, apsguide/3/04 4 the parent team and the ward staff on the most appropriate mode of analgesia throughout the peri-operative period, on an individual case basis. 4. Please inform the APS team for any cancellation of APS requests. What the OT recovery room staff should do Preoperative 1. After being informed of the daily pump allocation by 0830 the recovery room staff shall get the pumps and accessories ready, with proper labeling. 2. The PCA trolley shall be adequately stocked with all the accessories and consumables. Please let the APS team or the recovery room sister know of any problems. Post-operative 1. Control pain to an acceptable level in the recovery room using appropriate doses of opioid as per pain relief protocol (see later). 2. Make sure that the appropriate forms are filled in and signed by the anesthesiologist. Inspect the pumps and make sure that they are properly set, batteries functional, and lines unclamped, labeled and connected to the correct patient access. All pump cartridges must be locked. Switch on the pumps and check if they are programmed according to the nursing observation chart. Refer to the corresponding anesthesiologist in case of doubt. 3. Confirm with the corresponding anesthesiologist before starting the APS modality. Reeducate the patients on how to use the modalities properly. If the patient is deemed unsuitable for the device (narcotized patients with PCA, or patients in shock with CEI), stop the pump, and inform the anaesthesiologist. 4. Inform the APS team (DECT phone 6172 on weekdays 0800 - 1600, pager 1067 at other times) when discharging the patients from the recovery room. Handover the nursing observation and APS follow up forms to the ward staff. Issue loan forms for the pumps, including all the accessories. Put down patient particulars on the allocation board next to the recovery room control desk. What the APS team should do Pre-operative 1. APS team will triage the elective requests and inform OT recovery room at around 0830. If there are inadequate pumps to satisfy all requests, the APS team should inform the list anaesthetist, and make an effort to re-allocate pumps to those who did not receive priority earlier after the pain round at around 1000 a.m. Emergency and late elective requests will be apsguide/3/04 5 processed similarly after the elective requests are catered. Appropriate pumps should be allocated according to patient profile, resources available and ward staff familiarity with APS routine. 2. The APS team shall educate patients on how to use the PCA devices upon special request from the anesthesiologist. It does not apply to the first case of the morning list as they are already in the theatre before 0800 Post-operative 1. Upon notification of patient’s discharge from the recovery room, the APS team shall review the patient at the earliest convenience. The APS follow up form will be collected at the first visit and kept in the acute pain folder for future reference. The APS team shall make sure that all allocated pumps are traceable and operational. 2. The APS team shall make an effort to discuss with the anesthesiologist, the parent team or the general ward staff for any special request, deviations from the recommendations or any concerns regarding patient’s peri-operative pain management. This is to ensure that all parties can communicate and work together for the benefit of the patient. apsguide/3/04 6 ARRANGING APS SERVICE FOR ICU PATIENTS What the anaesthetist should do 1. All elective / emergency post-operative requests shall follow the same protocols as other OT patients What the intensivist should do 1. Please page the APS team (DECT phone 6172 during weekdays 0800 – 1600, other times 1067) for pumps. 2. The intensivist shall be responsible for obtaining the pump, setting it up and monitoring it during patient’s stay in the ICU. Patients in the ICU are critically ill and unstable. The intensivist shall make adjustments on the APS modality or regime according to the clinical needs. All changes shall be documented on the patient’s notes and the nursing observation chart. Please inform the APS team in case of termination of service or technical trouble-shooting. 3. Inform the Pain team (DECT phone 6172 on weekdays from 0800 till 1600, pager 1067 at other times) when discharging the patients from ICU to facilitate the continuation of pain management in the wards. Please remind the nurses to call if you are unable to do it yourself. In case the pain relief regime is different from the recommendations listed in these guidelines the APS team will switch them back to the standard recommendations before the patient is discharged to the ward. Please make sure that all forms and prescription orders are in accordance with the APS protocols (see below). What the APS team should do 1. Pump allocation shall be made as per emergency OT cases. Please inform the recovery room staff to prepare all the accessories for the ICU staff to collect. 2. The APS team shall review the patient at the earliest convenience. 3. Upon discharge from the ICU the APS team shall review and make sure the mode of analgesia is appropriate to the destined wards. This is to make sure that all patients in the ward follow the pain guidelines so as to ensure patient safety and staff familiarity. apsguide/3/04 7 What the ICU nurses should do 1. The intensivist is primarily responsible for setting up the pumps. Please inform the APS team (pager 1067 / DECT phone 6172) for assistance if necessary. 2. Make sure that the appropriate forms are filled in and signed by the intensivist. Stamps are available at the desk opposite to the nursing control desk (3027/3026) Inspect the pumps and make sure that they are properly set, batteries functional, lines unclamped, labeled and connected to the correct patient access. All pump cartridges must be locked. Check if the pumps are programmed according to the nursing observation chart. Refer to the intensivist in case of doubt. Re-educate the patients on how to use the modalities properly. If the patient is deemed unsuitable for the device (narcotized patients with PCA, or patients in shock with CEI), stop the pump, and inform the intensivist. 4. Inform the APS team (DECT phone 6172 on weekdays from 0800 till 1600, pager 1067 at other times) if not already done by the intensivist. Handover the nursing observation and APS follow up forms to the ward staff. Please make sure that the correct prescription form is used. Handover loan forms for the pumps, including all the accessories. apsguide/3/04 8 REQUESTING FOR APS SERVICE FOR PATIENS IN THE GENERAL WARD What the surgeon and ward nurses should do 1. Postoperative and non-surgical trauma patients who complain of inadequate pain relief from analgesics prescribed by the parent team may be referred to the acute pain team for assessment and management. 2. After assessed by the medical officer of the parent team, please page the pain duty MO (pager 1067). Please also send a consultation form to the Department of Anaesthesia and Intensive Care for documentation by the pain team. 3. As members of the APS team may be involved in other emergencies, they may not be available immediately upon referral, and the parent team shall continue with their conventional modes of analgesia. What the pain team could do 1. After assessing the patient, the pain team will adjust the medication, or arrange for alternate modality of pain relief as appropriate depending on the cause and severity of the pain, patient’s medical profile and resources available. 2. Once a treatment modality is started, the pain team will take responsibility of the patient’s pain relief and side effects associated with the pain relief treatment. The pain team will follow-up the patient as many times as necessary or at least once daily. apsguide/3/04 9 RECOVERY ROOM PROTOCOL Principles 1. Inadequate pain relief after surgery increases morbidity and delays patient discharge from recovery room. 2. A patient receiving the pain relief protocol requires constant assessment and monitoring. If the recovery area is too busy to provide this level of patient supervision, alternative methods of analgesia may be required. 3. The pain relief protocol should only be started by the anesthesiologist in charge of the case, who is familiar with the anaesthetic, medical and surgical history of the patient. He must provide adequate supervision for the nursing staff looking after the patient. Practice 1. At the recovery room of the Prince of Wales Hospital, the nursing staff have been trained and instructed to administered intravenous opioid for postoperative pain relief. They are competent in monitoring, assessing and managing the adverse effects and complications in post-anaesthetic patients. 2. Any patient who complains of distressing pain following surgery may be prescribed one of the following analgesia protocols. This includes patients who are prescribed intravenous patientcontrolled analgesia (IV PCA) as they are recovering from the anaesthetic. Remember that these patients will only obtain pain relief from the PCA if they are able to understand and activate the control button. 3. If you intend to prescribe intravenous opioid according to these protocols in the recovery room please chart it in the patient’s anaesthetic chart and inform the nursing staff. 4. Your patient should be comfortable, with a pain score of < 4 when they are discharged from the recovery room. Please assess your patient before you discharge them to the general ward. apsguide/3/04 10 Opioid Protocol Morphine (1 mg/ml) Adults 1. Dilute 15 mg morphine to 15 ml with normal saline 2. Dose: 1-2 ml (1-2 mg) every 5 minutes as required 3. For adult > 60 who is/or < 50 kg, 1 ml boluses may be more appropriate 4. Total dose limit to be stated by anesthesiologist. If pain not relieved with dose limit, the nursing staff will inform the anesthesiologist to reassess the patient. Paediatric patients 1. Morphine 20 mcg/kg q5min intravenously up to 5 doses, then review (See chapter on paediatric analgesia) Ketorolac Protocol Exclude contraindications before giving NSAID. Ketorolac (30 mg/ml) iv or im Adults under 65 years of age 1. Dose: 30 mg bolus followed by 10 - 30 mg Q6H to a max of 120 mg daily Adults 65 years and older 1. Dose: 10 mg bolus followed by 10 - 30 mg Q6H to a max of 60 mg daily Nursing instructions 1. Please refer to the nursing guidelines – recovery room pain relief. (See below) apsguide/3/04 11 SETTING UP INTRAVENOUS PATIENT-CONTROLLED ANALGESIA The following guidelines are recommended when using the GRASEBY 9300 pumps, GRASEBY 3300 pumps and ABBOTT APM-II pumps. These settings may be altered according to individual patient’s requirement during subsequent follow-up and reassessment. Graseby 3300 1. Use Terumo 50 ml syringes with luer lock, as the device has been programmed for use with this syringe, connect to free standing extension lines with pre-attached anti-siphon valves. 2. Dedicated intravenous line is recommended, use anti-reflux valve without 3-way stopcock. 3. Dilute 60 mg Morphine with total of 60 ml saline (final concentration: 1 mg/ml) 4. See section on Graseby 3300 for information on how to use the pump Recommended initial program Bolus dose 1-2 ml Lockout period 8 min Max. 4 hr dose limit 0.3 mg/kg 5. Many studies had shown that basal infusion during PCA neither improves the quality of analgesia nor the quality of sleep. Basal infusion is therefore not recommended. Graseby 9300 1. The pump should be programmed for PCA only. Ask the recovery room staff or the APS team (DECT phone 6172 / pager 1067) for assistance in programming the pump. 2. Use 250 ml internal reservoir cassettes, with anti-siphon valve included, and free standing 140 cm extension tubing 3. Dedicated intravenous line is recommended, use anti-reflux valve without 3-way stopcock. 4. Dilute 150 mg Morphine with total of 150 ml saline (final concentration: 1 mg/ml) 5. Remember to aspirate all air bubbles from the drug mixture bag via a 3-way stopcock or a female-female connector (comes with the 250ml internal cassette) 6. Recommended program: same as Graseby 3300 (see above) 7. See sections on Graseby 9300 for information on how to use the pump. apsguide/3/04 12 Abbott APM-II PCA 1. Use the 100 ml saline bag, another 40 ml of sterile saline, and the Abbott APM-II cartridge together with the anti-siphon valve and extension tubing 2. Dedicated intravenous line is recommended, use anti-reflux valve without 3-way stopcock. 3. Dilute 150 mg Morphine with total of 150 ml saline (final concentration: 1 mg/ml) 4. Remember to aspirate all air bubbles from the drug mixture bag before priming the cartridge 5. Set the pump for PCA boluses only, using ml as the unit of delivery, with air sensitivity at high level, and 4 hour limit activated 6. Recommended program: same as Graseby 3300 (see above) 7. See sections on Abbott APM-II for information on how to use the pump. The Y-piece connector 1. In case when only one intravenous line is available the following Y-connector can be used to accommodate both the infusion and PCA. It is available in the OT PCA trolley. 2. Please be reminded that this is only for the exceptional case, and it is reserved only for anaesthetists and members of the pain management team. Pat ient 's IV cannula Ant i-ref lux valve PCA Min vol ext ension Non-ret urn valve ( One-way) IV drip apsguide/3/04 13 Paediatric PCA regimen 1. Basic arrangements are similar to adult PCA. 2. As the handset of the Graseby 3300 may be too hard for the paediatric patients, use the Graseby 9300 or the Abbott APM-II only. Recommended initial program Morphine dilution 0.5 mg/ml Bolus dose 0.03 ml/kg (0.015 mg/kg) Lockout period 10 min Max. 4 hr dose limit 0.5 ml/kg (0.25 mg/kg) For more information, see section on paediatric analgesia apsguide/3/04 14 SETTING UP PATIENT-CONTROLLED EPIDURAL ANALGESIA Introduction 1. Patient-controlled epidural analgesia using pethidine is used at the PWH. Pethidine is selected based on its more favorable pharmacokinetic profile for PCEA when compared to morphine or fentanyl. Currently, PCEA using local anaesthetic is not used at this institution. 2. The Abbott APM-II is preferred in delivering the PCEA. If it is not available the same program can be applied to the Graseby 9300 pump. Recommended PCEA Pethidine regimen Pethidine concentration 10mg/ml Bolus dose 1-2ml (10-20mg) Lockout period 8 min Maximum 4 hr dose limit 3mg/kg Basal infusion zero Abbott APM-II and Graseby 9300 1. Setting is the same as for intravenous PCA 2. Dilute 1500 mg Pethidine into a total of 150 ml saline (10 mg / ml) 3. Make sure that they are labeled and connected to the epidural port Always use a filter to connect the epidural catheter to the PCA extension tubing. apsguide/3/04 15 SETTING UP CONTINUOUS EPIDURAL INFUSION ANALGESIA Introduction 1. It has been shown that epidural infusion of local anaesthetic + opioids can significantly reduce postoperative complications. 2. In order to minimize the amount of the solution used, the epidural catheter should be placed as close to the required dermatomes as possible. We recommend using: Mid-thoracic (T4-8) for upper abdominal and thoracic surgeries Low thoracic (T8-12) for lower abdominal surgeries Lumbar for lower limbs and pelvic surgeries 3. Epidurals can be associated with complications such as hypotension, spinal infection or hematoma. Such complications may affect the patient well after the operation. Please exercise caution especially in high risk patients for major surgery (e.g.: multi-lobar liver resections, kidney transplants). Regimes Bupivacaine and Fentanyl 1. Mix 60 ml of 0.5% Bupivacaine, 16 ml (800 mcg) of Fentanyl into the 250 ml saline bag 2. Final concentration: Bupivacaine 0.09%, Fentanyl 2.5 mcg/ml Final total volume: 326 ml (please set the reservoir / cassette volume to 320 ml. This is to make sure that it will alarm before the medication bag run out.) 3. Label the medication bag using the green additive gum label. Ropivacaine and Fentanyl 1. Mix 40 ml of 1% Ropivacaine, 16 ml (800 mcg) of Fentanyl into the 250 ml saline bag 2. Final concentration: Ropivacaine 0.13%, Fentanyl 2.6 mcg/ml Final total volume: 306 ml (please set the reservoir / cassette volume to 300 ml. This is to make sure that it will alarm before the medication bag run out.) 3. Label the medication bag using the green additive gum label. Equipment To reduce the need for refills of epidural infusion in busy surgical wards, we recommend using the Abbott APM-II or the Graseby 9300 (with external reservoir cassette) for infusions. apsguide/3/04 16 Abbott APM-II 1. Set the pump for continuous epidural infusion only, with low air sensitivity 2. Make sure that patient always has an intravenous line inserted when an epidural device is in use. 3. See sections on Abbott APM-II for information on how to use the pump Graseby 9300 1. The pump should be programmed for continuous infusion only. Please ask the recovery room staff or the APS team (pager 1067 / DECT phone 6172) for assistance in programming. 2. Use the external reservoir cassette and the anti-siphon valve, and connect it to the 140 cm extension tubing. 3. See section on Graseby 9300 for information on how to use the pump Securing the epidural catheters 1. No golden method so far. The catheter site should be dressed with a large transparent dressing with Micropore around the edge. The filter should be comfortably sited at the infraclavicular fossa and tagged with an “EPIDURAL” label. Recovery Room 1. Patient should be observed in the recovery room for at least one hour until haemodynamic stability is achieved. Ensure adequate sensory blockade before discharge patients to the ward. apsguide/3/04 17 DUTIES OF THE DAYTIME PAIN MO Introduction 1. At the Prince of Wales Hospital, one (or more) medical staff is rostered on weekdays to be the pain management MO. He is an integral part of the APS team on that day. 2. The aims of the pain MO module are: fulfill the operational need for the clinical supervision of the acute pain service, and / or other clinical duties as arranged in the roster; fulfill the requirement for training towards FHKCA or FANZCA; expose the trainee to aspects of acute and chronic pain management in preparation for their examinations; expose the trainee to pain medicine as a choice for further sub-specialisation education of undergraduate medical students 3. Appendix 1 and 2 refers to the minimum requirement for the pain medicine rotation for training towards FHKCA and FANZCA respectively. Duties of the Pain MO at PWH Acute pain services 1. The pain MO and nurse take over from the overnight Obstetric/pain MO at the 5/F common room at 0800. This includes a hand-over of APS patients who are first seen in the previous shift, those developed significant complications or difficulty in pain management, and handing over the pager 1067. All parties are expected to be present and punctuality is essential. In case the overnight person is engaged in other urgent clinical duties, the rest of the team will wait until everyone is available. 2. After the hand-over, the nurse will allocate pumps and inform the recovery room. The pain MO should be familiar with this process as he/she may be requested to allocate pumps in the event of the absence of pain nurses. 3. All new pain MO should be familiar with the acute pain service guidelines. 4. The pain MO will then conduct the morning acute pain round with the nurse. All patients under the care of the APS team must be assessed. 5. During the acute pain round, the pain MO is required to assess for the effectiveness and side effects of the pain management; review the equipment and medication prescribed; apsguide/3/04 18 make the appropriate clinical decision to terminate, change or adjust the pain management regimen, and treat any adverse effect; document and sign any prescription, patient’s progress notes and pain follow-up forms; trouble shoot simple problems related to the infusion pumps and set-up of the system; supervise the pain nurse and medical students 6. The pain MO will be responsible for acute pain consultation from the wards. The pain nurse may assist, under supervision, if the pain MO is engaged in other clinical duties and is not immediately available. 7. The pain MO shall hand-over to the night Obstetric/pain MO at 1600 at the 5/F common room. If the daytime pain MO is engaged in other clinical duties (see below) and is not available, he shall authorize the pain nurse to conduct the handover without delaying other clinical duties. The handover should include clinical information of all APS patients, as well as forthcoming patients to be reviewed, transfer of pager 1067, and other relevant matters. The pain MO or nurse shall highlight the problematic cases for the night Obstetric/pain MO to review. Chronic pain services 1. The pain MO at the PWH shall attend the pain consultations, chronic pain rounds, clinics and procedure sessions. 2. If the pain MO is rostered for the morning OT pain procedure session, he/she should attend the OT session first, and at the discretion of the pain specialist he/she will join the pain nurse after the pain procedure session to deal with any clinical matters arisen during the acute pain round. 3. The pain MO will be given the opportunity to assist and perform pain management procedures under the supervision of the pain specialist. 4. The pain MO is responsible for clerking inpatients admitted to the wards for pain management procedure in OT. These patients may be admitted to hospital on the day before or the day of procedure. The pain OT list should be drafted and submitted to the department secretaries before 1400 the afternoon before the OT session. 5. If there are no patients on the OT list, please inform the pain specialist AND the OT control before 1500 so that manpower arrangements can be made. Queries should be directed to the pain specialist. 6. There are 2 chronic pain clinics at the Prince of Wales Hospital. The pain MO will be required to clerk, assess and discuss the management plan for new patients attending the clinic. 7. Both pain clinic sessions are in the afternoon. The pain MO shall assist in the clinic until it ends. apsguide/3/04 19 8. The pain MO is also responsible for seeing in-patient chronic pain consultations under the supervision of the pain specialist. When the DPM trainee is available he will have the priority to review the patient. 9. All in-patient chronic pain consultations must be seen within the next working day by the assigned pain MO. 10. All non-urgent consultations should wait until after the pain clinic or other anaesthetic duties are accomplished. 11. All in-patient chronic pain consultations must be discussed with the senior pain doctor rostered on that day (either the DPM trainee or the specialist). It may be more appropriate to discuss the case before the pain MO document anything on the medical record. 12. The pain MO is expected to join the team on the regular chronic pain rounds. 13. The pain MO may be required to attend pain management sessions at different hospitals in the NTE cluster. Other clinical duties 1. Currently the pain MO may be required to attend in-patient pre-anaesthetic consultations and to provide anaesthesia at peripheral locations. Please note that all pre-anaesthetic consultations must be seen within next working day. 2. The pain MO may be required to teach medical students during the acute pain module. 3. The pain MO is one of the essential staff of the department when the Black Rainstorm signal or the Tropical Cyclone signal (no. 8 or above) is hoisted. He/she shall remain on duty according to the department guidelines. Education and training 1. The pain MO will be required to complete a presentation on a topic on pain management, either in the departmental CME meetings or the NTE pain CME meetings 2. The pain MO is expected to self-study on pain management under the tutorship of the pain specialists. A list of core topics is listed in the Appendix 3. 3. The pain MO will be required to log all acute and chronic pain cases that have been under his/her care during the pain rotation. apsguide/3/04 20 Appendix 1 FHKCA training requirements on pain management The following is an extract from the HKCA policy document “Vocational Training Guide for Anaesthesiology”. The full version http://www.hkca.edu.hk/vtganaes.pdf is available from the college website. Paragraph Statement 1.8 The Clinical Anaesthesia experience [referred to under section 1.6.2 and 1.6.4] must include an adequate exposure to all of the following CORE areas in anaesthesia. To ensure adequate exposure, a trainee is expected to have managed a minimum number of cases in each core subspecialty1 (as defined in the brackets ) over the 6 years of training 1.8.1 Anaesthesia for general surgery /urology /gynaecology (500 cases) 1.8.2 Anaesthesia for orthopaedics and traumatology (500 cases) 1.8.3 Obstetric anaesthesia (100 cases) and obstetric regional analgesia (50 cases) 1.8.4 Neuro-anaesthesia (100 cases) 1.8.5 Thoracic anaesthesia (50 cases) 1.8.6 Paediatric anaesthesia (100 cases of children < 6 years, including neonates) 1.8.7 Anaesthesia for Head & Neck / ENT/ Oro-facio-maxillary ( 00 cases) 1.8.8 Emergency / trauma anaesthesia (500 cases) 1.8.9 Acute pain management (300 patient-days) 1.9 Apart from the CORE areas, some experience in each of the following NON-CORE subspecialties1 would be required, particularly for future subspecialty development. Trainees will be required to complete two modules from category 1 and a minimum of 20 cases from category 2. 1.9.1 Category 1 NON-CORE modules 1.9.1.1 Ophthalmic anaesthesia (50 cases) 1.9.1.2 Day surgery anaesthesia ( 100 cases) 1.9.1.3 Anaesthesia in non-operating theatre locations including but not limited to Organ Imaging apsguide/3/04 21 Suite, Endoscopy Suite, Cardiac Catheterisation Laboratory, ECT (50 cases) 1.9.1.4 Pain medicine ( 50 chronic / cancer pain cases) 1.9.2 Category 2 NON-CORE Modules 1.9.2.1 Major vascular anaesthesia 1.9.2.2 Cardiac anaesthesia 1.9.2.3 Transplant anaesthesia 1.9.2.4 Neonatal anaesthesia 1.10 Elective options [referred to under Section 1.6.4] 1.10.1 Trainees may undertake the following or a combination of the following as part of their elective training:1.10.1.1 Clinical anaesthesia 1.10.1.2 Intensive / critical care medicine 1.10.1.3 Pain medicine 1.10.1.4 Other clinical specialties apart from anaesthesia, intensive / critical care medicine and pain medicine (most of the hospital based specialties will be accepted except pathology) 1.10.1.5 Research related to anaesthesia and/or intensive / critical care medicine and/or pain medicine apsguide/3/04 22 Appendix 2 FANZCA training requirements on pain management This is an extract from the ANZCA policy documents (TE10: Recommendations for Vocational Training Programs) relevant to pain training for anaesthetists. More details are available from the websites: http://www.anzca.edu.au/revfanzca/module10.htm and http://www.anzca.edu.au/publications/profdocs/traineduc/te10_2003.htm Recommendations for Vocational Training Programs (TE10) Paragraph Statement 2.7 The Training Modules outline a series of required learning experiences within the overall Training Program, including but not limited to: 2.7.5 Pain Medicine Trainees require 50 sessions (1/2 days) of pain medicine experience. While it will be acceptable for the majority of this experience to be in acute pain management, trainees must obtain experience in the management of chronic and cancer pain. MODULE 10 - Pain Medicine - Advanced Module Duration required: A minimum 50 sessions of clinical experience is required in Pain Medicine (Modules 1 and 10) - TE10 (2003) Recommendations for Vocational Training Programs. This Module must be completed during Advanced Training, preferably during ATY1 and ATY2. It may be completed as a single-block clinical rotation in pain management if the training institution can offer it, but may otherwise be completed in the normal course of clinical duties. Trainee's Aims This Module builds on clinical experience in pain management learned during Basic Training. apsguide/3/04 23 The aim of Module 10 is for Trainees to acquire clinical abilities and skills in managing perioperative post-traumatic, acute medical and persistent pain as an anaesthetist (but not to the level of a FFPMANZCA specialist). This includes learning to integrate and apply knowledge and skills in clinical management, such as in: Assessing pain Taking a "pain history" and examination Providing peri-operative and other acute pain relief Identifying and managing patients with persistent pain, including referral when appropriate, to pain medicine specialists Working in an interdisciplinary management paradigm Learning Objectives These are what the Trainee needs to learn. They are presented as: Knowledge Clinical management ("knows how") that applies knowledge and clinical skills to manage the patient Skills (clinical and technical) Attitudes and behaviors Assessment The Module 10 Supervisor will validate the Trainee's completion of the module in accordance with the process outlined in College Professional Document TE2. This will involve the Trainee assessing whether she/he has achieved the core aims (Trainee's aims) of the module and fulfilled the minimum clinical experience. The Module 10 Supervisor will review the Trainee's Learning Portfolio as part of this assessment. apsguide/3/04 24 The Supervisor of Training and other Consultants will evaluate the Trainee's overall performance in the In-Training Assessment (ITA) process. Aspects of clinical performance, education skills, and attitudes will be reviewed. The ITA will remain a formative assessment conducted every six months, independent of Module assessment. The Primary and Final Examinations will be summative assessments of the Trainee. Knowledge of basic sciences in Module 10 will be assessed in the Primary Examination. Principles of pain management, clinical management, and clinical skills (including regional blocks and relevant anatomy) in this Module will be assessed in the Final Examination. The Learning Portfolio is an integral tool for self-assessment (as well as for recording clinical experience and developing study plans). The Trainee is expected to self-evaluate his/her education skills and learning experience from the Learning Portfolio. For example, the Learning Portfolio should show the Trainee's progress through the Module, as records of clinical experience (sessions), nerve blocks learned, topics reviewed, and oral presentations delivered. Relevant ANZCA Professional Documents for Module 10 PS3 Guidelines for the Management of Major Regional Analgesia PS9 Guidelines on Conscious Sedation for Diagnostic, Interventional Medical and Surgical Procedures PS15 Recommendations for the Perioperative Care of Patients Selected for Day Care Surgery PS19 Recommendations for Monitored Care by an Anaesthetist PS20 Recommendations for Responsibilities of the Anaesthetist in the Post-Operative Period PS37 Statement on Local Anaesthesia and Allied Health Practitioners PS38 Statement Relating to the Relief of Pain and Suffering and End of Life Decisions PS41 Guidelines on Acute Pain Management Relevant FPM Professional Documents for Module 10 PM2 Requirements for Multidisciplinary Pain Centres Offering Training in Pain Medicine Reference Guidelines in Acute Pain Management NHMRC Guidelines - Acute Pain Management: the Scientific Evidence apsguide/3/04 25 Appendix 3 The MO/resident will be required to know: tools and clinical skills of assessing a patient in pain; the physiology of acute pain; the pharmacology of commonly used pain relief medications; the setup and how to operate a pain medication delivery system the advantages and disadvantages of different acute pain relief methods outcome measurements of pain management; tools for chronic pain assessment the pathophysiology of chronic pain assessment and management of cancer pain the advantages and disadvantages of different chronic pain relief methods pharmacotherapy psychological intervention physical therapy interventional techniques alternative medicine Specific chronic non-cancer pain conditions and their management Neuropathic pain CRPS Post-herpetic neuralgia Trigeminal neuralgia Myofascial pain Back pain and sciatica Phantom pain Headache including migraine Intractable angina Other aspects of knowledge, aptitude and skills applicable to the HKCA or the ANZCA training programme. apsguide/3/04 26 DUTIES OF THE PAIN NURSE Introduction 1. Pain management team acknowledges & respects fully the standards & practices of parent teams. 2. Pain nurse is working under supervision of the pain medical officer on duty. 3. Pain nurse would not prescribe nor alter prescriptions on drug prescription sheets from any medical staff. Upon cessation of pain control devices they may cancel the relevant prescriptions. 4. Pain nurse would assess & adjust pain control devices & other pain related management orders e.g. O2 therapy, pain observation frequency, re-programming of such devices, and termination of pain service. 5. In case of complications, standing orders as prescribed on observation record should be applied. Hospital resuscitation protocols should be followed during emergencies. 6. Parent team will be notified of patient’s condition as appropriate. Acute pain service (APS) 1. Provide clinical care to patients on pain relief treatment under APS. 2. Participate in APS patient-handover. 3. Organize allocation of pumps to users. 4. Conduct follow-up & review of APS patients. 5. Attend to ward consultation for acute pain service. 6. Attend to queries regarding matters related to APS from doctors, nurses & patients. 7. Attend to trouble shooting when appropriate. 8. Giving boluses of the APS analgesics under the supervision of the pain MO. 9. Supervise ward nurse in care of APS patients. 10. Participate in preoperative patient education. 11. Maintain pain relief pumps & other APS equipment. 12. Check & maintain stock of APS equipment & consumables. In-patient chronic pain consultation 1. Assist doctor in patient clinical care & management. 2. Participate in patient assessment & screening. 3. Participate in patient education on pain & pain management. apsguide/3/04 27 4. Collaborate with parent team’s treatment. 5. Ensure proper inpatient consultation record keeping. Pain management procedures 1. Keep record of all pain management procedures. 2. Arrange patient admission for pain procedure. 3. Assist doctor in pain management procedure. 4. Assist in subsequent follow up & patient care after procedure. Out patient pain clinic 1. Provide managerial support to ensure smooth running of outpatient pain clinic. 2. Assist doctor in patient clinical care & management. 3. Participate in patient education on pain & pain management. 4. Participate in patient assessment & screening. Administrative & Management 1. Provide managerial support to ensure smooth running of APS, inpatient & outpatient chronic pain service. 2. Keep record of APS data & chronic pain service data. 3. Prepare & send monthly pain services (APS, CPS, pain clinics & pain procedures) data to department heads. 4. Collect and compile outcome data for acute and chronic pain services. 5. Liaison with ward staff on matters related to APS & chronic pain services. 6. Assist in development & promulgation of guidelines to maintain smooth running of acute pain service & chronic pain service. 7. Plan & conduct quality assurance & other audits on acute & chronic pain services. 8. Supervise clerical assistant to pain service. 9. Supervise clerical staff in handling enquiries. 10. Liaise with the operating theatre, EMSD and various ward staff for maintenance of pain equipment & fixtures. Patient Education 1. Provide clinical education to both APS and chronic pain in-patients 2. Liaison with other disciples, organize and participate in out-patient education programs. apsguide/3/04 28 3. Report to doctors & involved disciples of patient’s progress & problems. Staff Education 1. Organize & participate in continuing nursing & medical staff education & refresher courses on pain management at NTE cluster. 2. Orientate new medical staff commencing pain service duty. 3. Assist in supervision of medical students. Research 1. Plan & conduct nursing related research projects in pain management. 2. Assist & collaborate with doctors on other research projects on pain management. apsguide/3/04 29 ACUTE PAIN SERVICE FOR THE NIGHT OBSTETRIC/PAIN MO Due to the expanding APS and the ever busy obstetric anaesthesia service, the following flowchart has been designed to assist the Night Obstetric / Pain Medical Officer to deal with acute pain consultations from the ward. Paged by ward staff MO Triage Able to attend Unable to attend Can wait > 1 hour Cannot wait > 1 hour Attend Patient WAIT See patient when able CONTACT Surgical team for assistance REVIEW case when able The surgical team should be able to assess the patient, give iv fluid challenge and prescribe supplementary analgesia (e.g.: single injection NSAID or opioid) under the supervision of the Obs/Pain MO. In all circumstances, the Obs/Pain MO MUST review the patient as soon as he/she is available. apsguide/3/04 30 PAIN MO GUIDELIENS FOR MANAGING PATIENTS WITH APS DEVICES Follow up 1. Patients must be seen by the pain team immediately after the operation and then at least daily by the pain team. Assess: Pain severity (using appropriate scoring system) Patient stability (blood pressure, SpO2, sedation score) Other relevant neurological testing (sensory, motor and urinary function) Side-effects (sedation, pruritis, nausea and vomiting) System set-up (venous / epidural site, dressings, connections, pump programme and history, power) 2. All relevant information should be documented in patient’s notes and APS follow-up sheets. 3. The Pain MO should resolve to one of the following options for each patient: Continue current analgesia Stop current analgesia Modify, such as addition of co-analgesics (see below), re-programming, switching to other APS modality, etc. Management of side effects or other trouble-shooting 3. Terminate APS service by crossing out the prescription order for the APS device. Make sure that patients receive adequate analgesia upon cessation of APS device. Please complete the follow-up form together with the patient satisfaction score and return it to the acute pain folder. 4. In case of un-certainty please discuss with the senior pain MO or the pain specialist. For special cases (e.g. when the practice deviate from the recommendations) please liaise with the anesthesiologist or the parent team concerned. apsguide/3/04 31 Problem solving Inadequate analgesia 1. All patients with inadequate analgesia must be attended at the earliest convenience. When the pain-duty MO is engaged in other urgent clinical duties, the medical staff of the parent team may be consulted for immediate rescue measures. Once the urgent duty is over the pain-duty MO shall review the case as soon as possible. 2. Check that the pump is running and the reservoir / infusion bag not empty. Exclude disconnections or occlusions. 3. Review the set-up and programme of the APS device. 4. Stable patients with intravenous PCA may receive boluses of morphine 0.02mg/kg intravenously at 5 minute intervals up to 0.1 mg / kg. 5. Stable patients with epidural / nerve blocks should have their sensory level checked. If the sensory level is inadequate, increase the basal infusion rate by 50%. If pain is distressing, give a 4 ml bolus of either the same solution or 0.125-0.25% bupivacaine and monitor the blood pressure every 5 minutes for 30 minutes. 6. All top-ups should be done and supervised by the Pain MO. The Pain MO also has to review the patients after the increment. 7. Consider co-analgesic eg IV/IM ketorolac. 8. Other considerations with ineffective analgesia include surgical complications, patient confusion, tolerance to analgesics, or presence of neuropathic pain. If still not effective, consult pain specialist. Hypotension 1. All patients with hypotension must be attended at the earliest convenience. When the pain-duty MO is engaged in other urgent clinical duties, the medical staff of the parent team may be consulted for immediate rescue measures. Once the urgent duty is over the pain-duty MO shall review the case as soon as possible. 2. Find out the cause of hypotension and determine the level of sensory blockade as well. apsguide/3/04 32 3. Give fluid ± vasopressors. 4. If other causes of hypotension are excluded and the level of sensory blockade adequate, stop the infusion for few hours and reassess later. Recommence the infusion at a lower rate. 5. If pain relief inadequate, continue the infusion after fluid ± ephedrine, consider co-analgesic eg iv/im ketorolac. 6. Consider converting to non-regional modes of analgesia if hypotension remained a problem whenever adequate blockade is established. Respiratory depression 1. This is life threatening and must be attended immediately. When the pain-duty MO is engaged in other urgent clinical duties, the intensivist on call should be consulted for immediate rescue measures. Once the urgent duty is over the pain-duty MO shall review the case as soon as possible. 2. All patients with significant sedation (difficult to arouse) are at risk of developing respiratory depression and should be treated. Classical signs such as pin-point pupils or slow respiratory rate are not sensitive, and arterial desaturation (reduced SaO2) is certainly too late. 3. Resuscitate immediately if patient is physiologically unstable. Secure patient’s airway, breathing and oxygenation with manual ventilation and oxygen supplement. Inform ICU. 4. Stop APS device immediately. Review the physical set up, connections, programme and consumption history. Document any abnormalities in patient’s notes and follow up sheet. 5. Naloxone should be available in every clinical area in the emergency trolley. It is usually not required for mild cases. Consider Naloxone if patient is at risk of developing significant sedation and deterioration. Dose: 0.1-0.2 mg iv/im/sc and repeat at 3 minute interval until patient recover or when a maximum of 10 mg is given. 6. Review and exclude total spinal blocks and local anaesthetic toxicity for patients with epidurals or other head and neck regional blocks. Pruritus 1. Give chlorpheniramine 5 mg iv or im. If tolerating oral intake, prescribe oral preparation 4 mg. apsguide/3/04 33 2. Consider Naloxone at 0.01 mg bolus iv, especially for pruritis associated with spinal opioids. Urinary Retention A trial of 30 minute is allowed. Perform up to two “in-and-out” catheterizations. Insert an indwelling catheter if necessary. Leg weakness 1. Consider stopping the epidural LA infusion and review in 2 hours. If leg weakness resolves, restart infusion with reduced concentration of LA by 30%. Review in another 2 hours, and consider alternate mode of analgesia if weakness recur or if pain become difficult to control. 2. If leg weakness persists despite discontinuation of epidural infusion, please continue close neuro-observation and look for signs of hematoma / abscess (such as back pain, root pain, fever, urinary retention or incontinence). Inform the neurosurgeon on-call if the clinical picture is compatible. Offer another mode of analgesia for rescue. Paresthesia 1. Mild paresthesia in the blocked dermatome may be expected. Consider reducing the concentration of LA. 2. Follow the leg weakness protocol if the paresthesia is dense and disturbing to the patient, or if it did not resolve with reduction in LA concentration. 3. Beware of high level (thoracic) paresthesia as it may indicate progression of a high block. Stop infusion and assess the level of block. Difficulty in Removing the Catheter 1. If difficulty is encountered, try to flex the back as much as possible. Pull the catheter out with a constant force. If it fails, contact the OT senior on call. apsguide/3/04 34 Unilateral or Patchy Neurological Blockade 1. Consider withdrawing the epidural catheter by 1 cm and top-up with another bolus of epidural LA. Consider switching to non-regional modes of analgesia. When Should the Catheter Be Removed? 1. When pain can be satisfactory managed by other modes of analgesia, or if the catheter failed to provide adequate analgesia despite adequate dose. 2. Haemodynamic instability from other causes like hemorrhage 3. Evidence of sepsis or bleeding tendency (corrected prior to removal) Prevention of infection 1. Use bacteria filter 2. Epidural site should be examined at least every day while the catheter is in situ, and once more within 1 day after catheter removal. 3. Epidural site dressing should be changed every 2-3 days if prolonged use anticipated 4. Premixed drugs for infusion should be discarded after 48 hours if unused Please remember to document all critical events in the follow-up charts, patient notes and critical incidence forms. Drugs stocked in the ward 1. Ephedrine 30 mg ampoule 2. Metaraminol 10 mg/ml vial 3. Naloxone 0.4 mg ampoule 4. Fentanyl 100ug ampoules 5. Buipivacaine 0.5% vial 6. 250ml normal saline bag apsguide/3/04 35 Equipment stored in ward 1. 0.22 um bacteria filter 2. 140 cm minimum volume extension tubing 3. Keys for pumps apsguide/3/04 36 GUIDELINES ON CO-ANALGESIA (last update: July 2004) Indications 1. When pain is not adequately relieved by PCA opioid or epidural LA infusion 2. When side effects of opioid are distressing Contra-indications 1. Patients with history of allergies to Non-steroidal anti-inflammatory drugs (NSAID) or paracetamol, asthma, personal or familial history of atopy or Steven-Johnson syndrome. 2. Patients with history of dyspepsia, gastric ulcer or GI bleeding, renal impairment, hypovolemia, bleeding tendencies e.g.: after massive transfusion (for NSAID), liver impairment (for paracetamol), or sedation tendency (for opioids) 3. Patients undergone procedures that carry high bleeding risk e.g.: after brain surgery (for NSAID) 4. Pain such as intestinal colicky pain or neuropathic pain may respond better to other therapy. Non-opioids 1. Paracetamol (tablet / syrup / suppository) Adult oral: 0.5 - 1.0 g q6h Adult rectal: 1-2 gm q6h Paediatric oral: 15 mg/kg q6h Paediatric rectal: 30 mg/kg q6h 2. Diclofenac = Voltaren (tablet / injectable) Adult oral: 25 mg tds or SR 100 mg daily Adult im: 25 mg q8h for 2 days Paediatric oral: 0.5-2 mg/kg/day 3. Ketorolac = Toradol (injectable) Adult im/iv: 15 mg q6h for 2 days NB: reduce dose for elderly / renal impaired patients apsguide/3/04 37 4. Indomethacin = Indocid (capsule / suppository) Adult oral: 25-50 mg tds Adult rectal: 100 mg bd Paediatric oral: 2 mg/kg/day Paediatric rectal: 2 mg/kg/day 5. Naproxen = Naprosyn (tablet) Adult oral: 250 mg tds 6. Ibuprofen = Brufen (tablet) Adult oral: 200 mg q6h 7. Mefenamic = Ponstan (capsule) Adult oral: 250 mg q6h 8. Piroxicam = Feldene (capsule) Adult oral: 10 mg bd 9. Sulindac = Clinoril (tablet) Adult oral: 200 mg bd 10. Ketoprofen = Orudis (injectable) Adult im: 50 mg q6h up to 3 days COX-2 specific NSAIDs on special request 1. Parecoxib = Dynastat (injectable) Adult iv/im: 40 mg q12-24h. Sample only. Need endorsement from senior staff of Department of A&IC 2. Celecoxib / Rofecoxib: only with authorization from Department of Medicine apsguide/3/04 38 Anti-spasmodic 1. Hyoscine methobromide = Holopon: 1 mg tds po 2. Hyoscine butylbromide = Buscopan: 20 mg im / sc / iv Opioid co-analgesic These are used only for weaning off the APS devices and should be prescribed by the pain MO only. Adding another opioid can confuse the regime, and increase the likelihood of side-effects. If a partial agonist is used, the efficacy of full agonist such as morphine may be reduced, and so far there is no evidence to show that one is better than any other. 1. Dextropropoxyphene = Doloxene (tablet) Adult oral: 64 mg qid 2. Dihydrocodeine = DF118 (capsule) Adult oral: 30 mg qid 3. Codeine (tablet / syrup) Adult oral: 30 mg qid Paediatric oral: 0.5 mg/kg q4h 4. Tramadol (capsule / syrup / injectable) Adult oral: 100 mg tds Adult im/iv/sc: 100 mg qid Paediatric oral/im/iv/sc: 1-2 mg/kg single dose 5. Dextropropoxyphene 32.5 with Paracetamol 320 = Dologesic (tablet) Adult oral: 2 tab qid 6. Dextropropoxyphene 65 with Aspirin 380 with Caffeine = Doloxene Co (capsule) Adult oral: 1 tab qid apsguide/3/04 39 PAEDIATRIC PAIN RELIEF Introduction 1. Simple invasive procedures can be done under sedation or topical anaesthesia with EMLA cream. 2. After minor procedures, oral or rectal non-opioid analgesics (e.g. paracetamol, NSAIDs) are often adequate. 3. Oral opioids (e.g.: codeine, morphine) can also supplement these simple analgesics. APS modalities such as intravenous PCA opioids and epidurals may also be suitable in selected cases that can understand and follow instructions. 4. Paediatric patients in severe pain or those who cannot comply may need iv opioids, either by nurse controlled analgesia or by infusion, under close monitoring. 5. Regional techniques performed during anaesthesia e.g. nerve block; caudal analgesia, etc are effective for postoperative pain relief. Simply infiltrate the wound with local anaesthetics can be of great help. Commonl analgesics Paracetamol 15 mg/kg q6h ie 60 mg/kg/day orally, (syrup 125 mg in 5 ml) 30 mg/kg q6h for rectal use (suppository 125 mg or 250 mg) Diclofenac 1 mg/kg q12h orally Indomethacin 1 mg/kg q12h orally or rectally Tramadol 1 mg/kg single dose orally or im or iv apsguide/3/04 40 Codeine 0.5 mg/kg in q4h orally (Syrup 25 mg/5 ml) Morphine 1. OT recovery room protocol 0.02 mg/kg q5min iv up to 5 doses, then review 2. PCA protocol Morphine concentration 0.5 mg/ml Bolus dose 0.03 ml/kg (0.015 mg/kg) Lockout period 10 min 4 hr dose limit 0.5 ml/kg (0.25 mg/kg) 3. Oral 0.2 mg/kg q4h up to maximum of 1 mg/kg/day (syrup 1 mg/ml) 4. Continuous iv opioid infusion (not for neonates) Morphine concentration 0.1 mg/ml Infusion rate Start at 0.01 mg/kg/hr (titrate 0.01-0.06 mg/kg/hr) *This modality of pain relief should only be started after discussion with the pain management team. Other useful drugs Metoclopramide 0.1 mg/kg q8h po/im/iv (tab 10 mg, syrup 5 mg/5 ml) apsguide/3/04 41 Chlorpheniramine 0.4 mg/kg/day in 3 divided doses (tab 4 mg, syrup 2 mg/5 ml) po 0.2 mg/kg single dose single iv/im injection Naloxone 10-50 mcg/kg iv, repeat at 3 minute intervals till responsive, followed by 1-5 mcg/kg/hour infusion till the offending opioid is eliminated. apsguide/3/04 42 FORMS AND STAMPS FOR THE ACUTE PAIN SERVICE Introduction Documentation is an important part of the APS for these reasons: Communication between the APS team and the ward staff Reinforcement of monitoring and safety measures Facilitate hand-over and continuation of care Auditing, research and quality assurance Forms 1. Booking form This is available at the 5th Floor common room (next to the door) or the operating theatre control desk. The collection boxes are located next to the forms. Please complete all particulars and return before 0800 on the day of elective surgery. 2. Acute pain follow-up form This is available at the operating theatre PCA trolley, the acute pain folder and the intensive care unit. This form must be completed upon initiation of all APS device. Upon discharge of patients from the recovery room, the APS team will be informed, and during the first follow-up the APS team will retrieve the follow up form, and it will serve as the patient record within the team. It must be updated each time during the acute pain round. After completion of the last follow-up, please put it in the “completed follow up” section of the acute pain folder. It will be audited and archived by the APS team. Please document all pain related clinical matters on this form. apsguide/3/04 43 3. APS nursing observation form This is kept at the same places as the follow-up form. Again it must be completed upon initiation of the APS device. It is for charting patient observations by the ward nurses, and it will remain in patient’s folder even after the APS device is not in use. Please put down any specific nursing orders (e.g.: frequency of observation) on this form. 4. Patient’s progress notes Please put down our standard post-op. orders for all patients at the initiation of the APS device. They are summarized in the large blue stamp at the PCA trolley. Please sign and put down anything you want to tell the primary team (e.g.: oxygen supplement). 5. Patient’s prescription forms Details of APS orders have to be documented in the yellow prescription form. One stamp for each regime is available at the PCA trolley. Please use the responding stamp, date and sign accordingly. Please prescribe anti-emetics as appropriate. Cross out all sedatives or narcotic analgesic prescription on both the yellow and white prescription forms, and on the side of the yellow form please stamp please add another stamp to remind others not to do so. apsguide/3/04 44 Stamps for yellow prescription form: Left: PCA regimes Right: epidural regimes Warning stamps for the side of the yellow prescription form apsguide/3/04 45 GRASEBY 3300 PUMP Introduction At present all Graseby 3300 have been configured only for intravenous PCA without background infusion. This device should be hooked onto the iv pole by the patients’ bedside during use. Syringe Barrel Clamp Syringe Plunger Clamp Cover Flap Polycarbonat e Cover Pat ient Hist ory Key LED Display Setup 1. Use a Terumo 50 ml syringe with luer lock as the pump has been programmed to recognize this model and size. When placing syringe, lift up the barrel-clamps gently and slide the syringe onto position. Make sure that that the barrel-clamp is securely fastened on to the body syringe and the plunger-clamp is then clamped onto the syringe plunger. The plungerclamp can be adjusted into the clamped-position only when the two little buttons on the plunger surface (of the plunger-clamp) are depressed. 2. Always use the extension tubing together with the anti-siphon valve. 3. Make sure that the handset is connected tightly to the nipple at the back of the pump. The pump will fail to activate even if there is a partial leak in the tubing and connections, and there are no alarms for that. 4. Always connect the pump to the AC supply. The AC power indicator lamp will illuminate. apsguide/3/04 46 The batteries will be fully charged if the pump has been connected to main (AC) power for at least 14 hours. When fully charged, the batteries will last for approximately 8 hours under normal operating conditions. 5. Secure tightly onto IV pole at or below the level of the patient to prevent potential siphoning effect. 6. Make sure that the key is detached from the PCA after setting up the pump. 7. Please refer to the manual for technical details. apsguide/3/04 47 GRASEBY 3300 PUMP QUICK REFERENCE GUIDE Function buttons On/off This button switches on and off the power to operate the pump. Start/Stop This button turns on and off the PCA program Enter This button reviews the preset PCA program Patient history This button reviews the total amount of analgesic used, number of actual demands and number of successful demands. or This button is for programming the PCA settings. Only to be used by the anaesthesiologist or the pain team. Patient connection 1. Always use the extension tube (140 cm) with anti-siphon valve 2. A dedicated iv access is preferable. Use an iv cannula > 22G with an anti-reflux valve. Stopcocks are not allowed. 3. Tegaderm and micropore dressing for easy observation of cannula insertion site. 4. In case of difficulty with intravenous access and only one line is available for both intravenous fluid and PCA, the Y-piece can be applied. It is only available to the pain team staff Trouble shooting 1. Pump problems i. unable to start PCA - check that the syringe is fitted correctly - check that the syringe plunger clamp is firmly applied onto the plunger - check that the cover is closed properly ii. spontaneous PCA doses apsguide/3/04 48 - intrinsic pump fault - electromagnetic interference - exclude siphoning effect - check that the syringe plunger clamp is firmly applied onto the plunger - check for cracks, leak in the system iii. spontaneous reprogramming e.g. electromagnetic interference iv.unable to trigger demand - inform Pain Team as pump needs to be withdrawn and checked 2. Unable to trigger PCA demand i. poor patient’s technique ii. faulty demand button iii. disconnected or loose (leaking) connection tubing iv. pump failure - DO NOT test demand button with system still connected to patient if fault is suspected - inform Pain Team if fault is suspected 3. 4 Hourly Dose Limit Exceeded Alarm - may occur if dose limit exceeded - silence alarm - ensure patient not over sedated - if patient not using PCA well - needs re-education - if using PCA well but still high pain score - inform Pain Team 4. Occlusion Alarm - check patency of IV cannula - exclude kink, occlusion, obstruction in the system eg extension tubing 5. AC Failure / Low Battery Alarm - check and reconnect power cable to main AC supply apsguide/3/04 49 Alarms Graseby 3300 PCA pump has 3 different alarm sound types 1. Loud continuous alarm 2. Quiet “chirping” alarm 3. Loud “pulsed” alarm Loud Continuous Alarm Cause: An interval fault condition is detected e.g. *FAULT CODE 7* This alarm cannot be silenced Action: Press off Disconnect the AC main cable Inform Pain Team Cause: WARNING: LOW BATTERY Loud continuous (2 mins duration) Very low battery This alarm cannot be silenced Action: Switch off the pump Reconnect the AC main cable Switch on pump Quiet “Chirping” Alarm apsguide/3/04 50 Accompanied by an explanatory message on the display at 10 sec intervals Cause: WARNING: COVER NOT CLOSED (CLOSE COVER & PRESS START) Cause: WARNING: PUMP NOT RUNNING PRESS START Cause: WARNING: SYRINGE NEARLY EMPTY (LESS THAN 3.0 mls) Action: Prepare next syringe if PCA is to be continued. Cause: WARNING: MAINS FAILURE PUMP NOW ON BATTERY Action: Reconnect AC mains cable as soon as possible. Cause: WARNING: LOW BATTERY Action: Reconnect AC main cable now. This alarm cannot be silenced. apsguide/3/04 51 Loud Pulsed Alarm Cause: PUMP STOPPED: OCCLUSION (RELEASE PLUNGER CLAMP) The infusion line is blocked. Action: Open cover, release syringe plunger clamp and deal with occlusion Cause: PUMP STOPPED: SYRINGE REMOVED Action: Replace syringe. Cause: PUMP STOPPED: TOTAL DOSE LIMIT XXX g IN Y HOURS EXCEEDED Action: Find out causes for excessive usages Inform Pain Team Cause: PUMP STOPPED: BY EXTERNAL MONITOR A monitor alarm has triggered and stopped the pump Action: apsguide/3/04 52 Check that PCA programme has not altered Inform Pain Team Press START if safe to do so Please refer to the acute pain team in case of queries, other kinds of trouble shooting or any other technical / clinical problems. Switching off Switching Press STOP. Insert the key into the pole clamp lock and turn through Off: 90o. This opens the syringe cover. Press STOP again Press the OFF button to switch the pump off. apsguide/3/04 53 GRASEBY 9300 PUMP Introduction The Graseby 9300 is an ambulatory peristaltic pump for PCA or continuous infusions. It operates on batteries (2 alkaline AAA batteries) and can be carried by a fabric pouch. This is to facilitate patients’ ambulation. It can accommodate different medication reservoirs (see below) for different purposes. apsguide/3/04 54 Setup 1. There are two kinds of cassette: the 250 ml internal cassette for PCA, and the external cassette with spike for continuous infusions. Both cassettes carry internal locking so that once detached from the pump they are automatically invalid. This is to avoid inadvertent reuse of old cassettes. Make sure that they are firmly connected to the pump before starting. 2. The pump uses two alkaline AAA batteries. On average new batteries will last for 7 days, and in general infusions consume more power than PCA mode. 3. You can prime the internal cassettes either by a female-female connector or a 3-way stopcock. All air bubbles must be aspirated before the cassette is attached onto the pump body, as the internal lock will prevent further manipulations afterwards. You can also prime the system by pushing on the PURGE button two times and hold while the pump is in the unlocked mode. This will give a 2ml bolus enough for the tubing. 4. Always use the anti-siphon valve attached inside the cassette package, and the 140 cm extension tubing. 5. The Graseby 9300 pump has 2 levels of keypad lock. Please select full lock (with both lock signs highlighted) by pushing on the KEY button and entering the code 9300 by using the ▲ and ▼ buttons, followed by the KEY button again. 6. The cassette should be locked by the pain team. 7. Please refer to the manual for technical details. apsguide/3/04 55 GRASEBY 9300 PUMP QUICK REFERENCE GUIDE apsguide/3/04 56 Note: Please contact Pain Team by Pager 1067 / DECT phone 6172 whenever in doubt about integrity of PCA / CI pump eg. pump fallen to ground - disconnect PCA / CI line from patient first and inform Pain Team apsguide/3/04 57 Warnings and Alarms DISPLAY POSSIBLE CAUSES ACTION 1. STOP infusion WARNING: LOW Battery charge is low. BATTERY 2. Press OFF and replace batteries (size AAA) 3. Press ON and START WARNING: EMPTY Cassette nearly empty. CASSETTE 1. Press STOP and change cassette 2. Reset the cassette volume 3. Press START 1. Press CASSETTE EMPTY Cassette empty. and STOP and change cassette 2. Reset the cassette volume 3. Press START WARNING: PUMP NOT RUNNING Pump stopped and Press START or OFF unused. 1. Press OCCLUSION Tubing is clamped. 2. Clamp tubing with Blue clamp Kinked tubing. Tubing too narrow. Blockage at infusion site. 3. Clear occlusion 4. Open clamp 5. Press START 1. Press CASSETTE NOT FITTED Cassette removed while pump is running or cassette not loaded properly. apsguide/3/04 58 2. Inform pain team Warnings & Alarms 1. Press AIR IN LINE OR EMPTY Air in cassette tubing. Cassette empty. and STOP 2. Clamp tubing 3. Disconnect patient tubing 4. PURGE to remove air or Remove and replace empty cassette 1. Press CASSETTE VOL TOO Cassette volume has not SMALL 2. Reset the cassette volume been re-entered for new cassette. 1. Press OFF FAULT XX Pump Failure 2. INFORM Pain Team 3. Engineer attention is necessary Note: If two alarm conditions occur at the same time, silencing one may result in another alarm being displayed. Please refer to the acute pain team in case of queries, other kinds of trouble shooting or any other technical / clinical problems. apsguide/3/04 59 ABBOTT PAIN MANAGER (APM-II) PUMP Introduction The Abbott APM-II is a multi-purpose infusion pump. It is a peristaltic pump with external medication reservoirs connected to specific cartridges. It can be programmed to deliver infusions, PCA or a combination of both. Most of the programme can be re-configured. It is embedded in a rectangular PVC box together with the medication bag under lock and key, and the whole complex is to be attached on a pole / drip stand. apsguide/3/04 60 Setup 1. The Abbott APM-II operates on 2 alkaline batteries (9 Volt size D) that can maintain up to 5 days on maximal workload. Alternatively it can be connected to a transformer for external power. That is the case in the obstetrics suite. Transformers are available at the obstetrics suite. 2. This pump uses an external cartridge for all modes of analgesia. It also has a built-in air filter, anti-siphoning valve and extension tubing. During the initial set up make sure that the tubes are not kinked inside the plastic case 3. Make sure that the keypad is locked before starting. To unlock, slowly press ENTER, then ▲ twice. Lock by slowly press ENTER, then ▼ thrice. 4. Make sure that the case is locked before sending it to the ward. Keys are kept in the recovery room (PCA trolley), the acute pain folder, the labour ward, the ICU and all the surgical and orthopediac wards. 5. Please refer to the manual for technical details. apsguide/3/04 61 ABBOTT PAIN MANAGER (APM-II) PUMP QUICK REFERENCE GUIDE Procedures for entering a new program 1. Press RUN / STOP to stop the pump 2. Press REVIEW / CHANGE 3. Press 2 1. CHANGE PROGRAM 2. NEW PROGRAM 4. Press NO to clear only the current program (The pump enters the programming mode, then you can set the new program now, after the air sensitivity setting is confirmed the pump enters the stop mode.) 5. Press RUN / STOP to restart the pump. Procedures for renewing the drug mixture 1. Prepare the drug mixture a/c prescription 2. Aspirate all the air from the fluid bag 3. Press RUN / STOP to stop the pump 4. Press ENTER + ▲ + ▲ to unlock the keypad 5. Clamp the tubing 6. Open the lockbox with the key 7. Remove the spike from the empty fluid bag 8. Insert the spike into the new fluid bag 9. Hang the bag inside the lockbox & lock it 10. Make sure the tubing is not kinked 11. Press RESET then 2 , it show "NEW CONTAINER” and the total volume will be automatically reset 12. Press ENTER + ▼ + ▼ + ▼ to lock the keypad 13. Release clamp & press RUN / STOP to restart the pump 14. Make sure “TOTAL X.X ML” with a bar running clockwise apsguide/3/04 62 Check Consumption (Demand / Good) or Container Information 1. 2. 3. 4. 5. No need to stop the pump. Press HISTORY Press 2 then press 1 Press ▲ to review the consumption, or press ▲ consecutively three times to check *VTBI (container information) Press any other keys to return to original display. To display shift information 1. No need to stop the pump. 2. Press HISTORY 3. Press 2 then press 2 to display shift information. 4. Press ▲ to review the consumption, or press ▲ consecutively three times to check *VTBI (container information). 5. Press any other keys to return to original display. * VTBI=volume to be infused Review program 1. 2. 3. 4. No need to stop the pump. Press REVIEW / CHANGE Press 1 then press ▲ to review the program or press ▼ to scroll backwards. The pump will automatically return to the original display if no key is pressed within 30 seconds. Alarms and Troubleshooting Occlusion 1. 2. 3. 4. 5. Press SILENCE to mute the alarm. Press RUN / STOP to stop the pump. Check the reasons for occlusion. Ensure the patency of the delivery circuit. Press RUN / STOP to restart the pump. Check Cartridge 1. 2. 3. 4. Press SILENCE to mute the alarm. Press RUN / STOP & open pump latch. Remove cartridge & tubing. Align dot in red circle of cartridge. apsguide/3/04 63 5. 6. Reinsert cartridge in pump. Press RUN / STOP to restart the pump. Almost Empty Delivery will complete in less than 30 min. for rates above 1 ml/hr. 1. Press SILENCE to mute alarm for two minutes. 2. Press RUN / STOP to stop the pump & clear the message. Low Battery 1. 2. 3. Press SILENCE to mute the alarm. Change batteries (Two 9V alkaline batteries) or connect to AC power. Press RUN / STOP to restart the pump. Malfunction Alarms The system detects a mechanical or computer problem. The alarm cannot be muted. 1. Record the malfunction codes on the observation chart. 2. Press ON / OFF to turn the pump off. 3. Disconnect AC power & / or remove batteries. 4. Inform Pain Team. Check Printer Alarm This alarm will be activated when the PRINTER key is pressed accidentally. 1. Press PRINTER key again to de-activate it. Air-in-line Alarm 1. Press SILENCE 2. Press RUN / STOP to stop the pump. 3. Unlock the keypad with ENTER + ▲ + ▲ 4. Disconnect the tubing from the patient. 5. Press PURGE to expel the air bubbles. 6. Lock the keypad with ENTER + ▼ + ▼ + ▼ 7. Press RUN / STOP to restart the pump. Please refer to the acute pain team in case of queries, other kinds of trouble shooting or any other technical / clinical problems. apsguide/3/04 64 NON-AXIAL REGIONAL ANALGESIA Introduction Regional analgesia techniques may provide excellent pain relief for trauma and postoperative patients. Some of these techniques such as continuous brachial plexus analgesia, intrapleural analgesia, paravertebral blockade and femoral/lateral cutaneous nerve of thigh/obturator (3 in 1) blockade may be possible for postoperative pain relief with a catheter inserted peri-operatively. If you wish to commence regional analgesia, you may request for the Abbott APM-II or the Graseby 9300 infusion pumps. Brachial Plexus Infusion 1. For intra-operative anaesthesia, give 0.5% bupivacaine at 0.5 ml/kg slowly with increments. GA is optional. 2. For postoperative analgesia, use 0.125% bupivacaine at 0.1-0.2 ml/kg/hr. Start at the lower rate in recovery room. The rate may be adjusted when appropriate during reassessment. 3. For the continuous infusion in the ward, add 80 ml bupivacaine 0.5% into a 250 ml normal saline bag. This will give bupivacaine 0.125% and a volume of 330 ml. The ward nurses should be able to change and refill the infusion drug if the drug mixture is charted and clear instruction written on the relevant charts. 4. Chart p.r.n. Dologesic 2 tabs q4h p.r.n orally and Voltaren 25 mg q8h or morphine 5 mg q4h intramuscularly depending on contraindications. 5. Please fill in the pain follow-up form and the observation chart as for other pain patient. The pain team will follow-up these patients as any other patients on PCA or epidural infusion. 6. The catheter may be left in-situ for 3-4 days. Paravertebral Infusion 1. For intra-operative anaesthesia it is usually used to supplement a general anaesthesia. 2. Use 0.25% Bupivacaine for post-operative analgesia. Withdraw 100 ml saline from a 250 ml saline bag, then dilute 150 ml of 0.5% Bupivacaine into the remaining 150 ml of saline, making a total volume of 300 mls. 3. A stamp for the regime is available at the PCA trolley. Please be reminded that the total volume of the reservoir is 300 mls and the pumps should be programmed accordingly. Suggested infusion rate: 5-10 mls per hour. apsguide/3/04 65 4. Chart rescue opioids (e.g.: morphine 5 mg q4h subcutaneously p.r.n.) or oral co-analgesics if patient can tolerate oral intake. 5. Fill in the forms as per other patients with APS devices. The APS team will review the patient as scheduled. apsguide/3/04 66 PRIVATE PATIENTS’ FEE Please note that private charges have been revised and will be charged according to the S.S No. 4 to Gazette No. 13/2003: Section 1 Private Charges 1. Inpatient Charges 1.2 Doctor Fee: Daily Medical Attendance / Consultation $1500 This will cover all fees related to in-patient pain-related consultations and follow ups, including acute pain round, chronic pain round and other follow-up visits whenever a medical doctor is present. Please fill in the appropriate charge form PWH 101 when acute pain service is terminated. Thank you. apsguide/3/04 67 NURSING GUIDELINES – RECOVERY ROOM PAIN RELIEF Principles 1. Inadequate pain relief after surgery increases morbidity and delays patient discharge from recovery room. 2. A patient receiving the pain relief protocol requires constant assessment and monitoring in the recovery room (RR). If the recovery area is too busy to provide this level of patient supervision, alternative methods of analgesia may be required. 3. The anesthesiologist who prescribed the protocol must provide adequate supervision of the patient and the nursing staff looking after the patient. 4. The pain relief protocol should only be started by the anesthesiologist in charge of the case, who is familiar with the anaesthetic, medical and surgical history of the patient. Medical Protocols Morphine (1 mg/ml) Adults 1. Dilute 15 mg morphine to 15 ml with normal saline 2. Dose: 1-2 ml (1-2 mg) every 5 minutes as required 3. For adult > 60 who is/or < 50 kg, 1 ml boluses may be more appropriate 4. Total dose limit to be stated by anesthesiologist. If pain not relieved with dose limit, the nursing staff will inform the anesthesiologist to reassess the patient. Paediatric patients 1. Morphine 20 mcg/kg q5min intravenously up to 5 doses, then review (See chapter on paediatric analgesia) Ketorolac Protocol Exclude contraindications before giving NSAID. apsguide/3/04 68 Ketorolac (30 mg/ml) iv or im Adults under 65 years of age 1. Dose: 30 mg bolus followed by 10 - 30 mg Q6H to a max of 120 mg daily Adults 65 years and older 1. Dose: 10 mg bolus followed by 10 - 30 mg Q6H to a max of 60 mg daily Nursing Protocol 1. If a patient complains of pain or request analgesia, assess the pain score to determine the severity of pain. If the pain score is > 4, inform the anesthesiologist in-charge of the patient. Inadequate pain relief should be treated without undue delay. 2. The anesthesiologist may prescribe the recovery room pain relief protocol. 3. The opioid must be prescribed by name e.g.. “IV morphine protocol”. Label the syringe with the drug name and concentration, and patient name. 4. All patients should be on supplementary oxygen. 5. Assessment must include BP, pulse, SpO2, pain score, sedation score, RR every 5-10 minute. 6. Flush IV line with saline or IV fluid after injecting opioid. 7. Stop pain relief protocol when the patient is comfortable. Patient need not to be completely pain free to be comfortable. 8. This protocol may precede the commencement of PCA opioid. Start PCA when patient is adequately awake and pain moderate. Stop pain relief protocol when PCA is started. 9. Inform the anesthesiologist responsible for that patient of any side effects e.g. hypotension, low urine o/p, SpO2, severe, nausea, vomiting, itchiness. 10.Side effects may be treated if treatment drugs already charted e.g. antiemetic. If not, inform the anesthesiologist. 11.Refer to the anesthesiologist responsible for that patient for any queries related to the protocol. 12.Inform duty anesthesiologist if the anesthesiologist responsible for that patient is not available. 13.Inform the pain team (DECT phone 6172 on weekday 0800-1600, pager 1067 at other times) when patients with PCA or epidurals are discharged from the recovery room. This is to make sure that the pain team knows where to follow the patient up. apsguide/3/04 69 Inform anesthesiologist if: 1. Sedation score of 3 or greater 2. Respiratory rate of 8/min or less 3. Nausea or vomiting 4. Severe itch 5. Systolic blood pressure of less than 90 mmHg or 20% lower than baseline blood pressure Sedation score 1 = alert 2 = drowsy, easy to arouse 3 = difficult to rouse 4 = unconscious, not arousable S = normally asleep, easy to rouse. Pain score Where possible, record the verbal analogue pain scale using the ruler or the verbal numeric scale. The patient should be asked to rate their pain on a scale of 0 to 10 0 = no pain apsguide/3/04 10 = worst imaginable pain 70 NURSING GUIDELINES – CARE OF PATIENTS ON PATIENT CONTROLLED ANALGESIA (PCA) PCA patient on return from OT 1. Pain Team has been informed by the OT recovery room staff and they will review the patient at their earliest convenience. 2. Place the PCA pump at or below the level of the patient. 3. The Graseby 3300 pump need external power source. After plugging into the socket, make sure the “AC” light panel is lit. 4. Check that the PCA tubing and connections are correct and tightly fitted. 5. Separate nurse calling button from the PCA button. 6. Confirm that patient is familiar with PCA 7. Make sure that he is the only person allowed to press the demand button except in the case of Nurse controlled analgesia (NCA) PCA programme 1. Do not leave the PCA key on the pump to prevent unauthorized programming. Keep it in the DDA cupboard. 2. Check that PCA pump is programmed as charted. 3. PCA programme should not be changed by anyone except Pain Team. PCA system IV PCA 1. A dedicated peripheral line is recommended for PCA. Special Y-piece connectors are reserved for cases when only one line is available for both infusions and PCA. It is only available to the pain management team. 2. No stopcock should be used in the PCA system. 3. Separate IV access must be available while patients are still on PCA. PCEA 1. If PCA is used via the epidural route, a bacterial filter 0.22 m must always be on the line. 2. System should be clearly labeled “Epidural Infusion”. 3. No other drugs to be injected into the epidural analgesia line. 4. Separate IV access must be available while patients are on epidural infusion apsguide/3/04 71 Drug Chart 1. Check that prescription for PCA drug refilling is charted. If not, inform the pain team. 2. Check that anti-emetic P.R.N. is prescribed. 3. No co-analgesics, other opioid analgesia or central depressant is allowed during the use of PCA except prescribed or agreed to by pain team. 4. Supplementary oxygen should be given to all patients on PCA for the first 24 hours or as ordered by anaesthetist until reviewed by pain team. Charting of Observation Use Acute Pain Service Observation Chart. Observations should be made hourly until reassessed by the pain team for: Blood pressure and Pulse SPO2 Urine Output and CVP if catheters are present Pain Score Sedation Score Respiratory Rate Number of Demands and Good Leg weakness (if on epidural PCA or PCEA) Refilling & Changing of PCA Syringe Preparation of drugs: Wash hands before preparing the drugs For Graseby 3300 always use a NEW 50 ml Terumo syringe with luer lock for refilling 3 checks 5 rights with another nurse for all drugs and dilution when mixing the drugs as prescribed in the “As required” column of the drug chart. Usual PCA prescription : Graseby 3300 Morphine 60 mg diluted to 60 ml with normal saline (1 mg/ml) Graseby 9300 or Abbott APM-II i. Morphine 150mg diluted to 150 ml with normal saline (1mg/ml) ii. Pethidine 1500mg diluted to 150ml with normal saline (10mg/ml) apsguide/3/04 72 Label the syringe/cassette clearly with i. Name of drug ii. Dilution iii. Date and time of preparation iv. Patient’s name and bed v. The person who prepare the drugs Ensure right route for PCA: intravenous or epidural Make sure cannula is functioning; no sign of tissue, displacement or kinks Ensure no stopcock tap in PCA line Expel air in the syringe/cassette and connect to the extension tube with anti-siphon valve Recheck all connections and clamps for proper installment before restarting PCA Check that PCA programme is not cleared or altered during syringe/cassette change Chart refilling of drugs on patient’s drug chart Stopping PCA The pain team usually stops the PCA when satisfactory pain relief is achieved by oral analgesic medication or as the pain improves with healing after a few days. When PCA or epidural infusion is stopped, please make sure that parenteral and/or oral opioid analgesia is prescribed on the “As Required” column of the drug chart. Please return the PCA infusion pump to OT recovery room or the labour ward according to the loan form issued as soon as possible. Discard the remaining opioid drugs. Inform Pain Team if pain is poorly controlled by parenteral opioid after stopping PCA. The pain team will review the patient again if necessary. Contact Pain Team Pager 1067 /DECT phone 6172 for any query. apsguide/3/04 73 NURSING GUIDELINES – CARE OF PATIENTS ON CONTINUOUS EPIDURAL INFUSION ANALGESIA CEI patient on return from OT 1. Check that the CEI tubing and connections are correct and tightly fitted. 2. Place pump by the patient. 3. Both the Graseby 9300 and Abbott APM-II run on alkaline batteries. CEI programme 1. Do not leave the key on the pump to prevent unauthorized programming. Keep with DDA cupboard key. 2. Check that CEI pump programmed as charted. 3. CEI programme should not be changed by anyone except Pain Team. Continuous infusion 1. A bacterial filter 0.22 m must always be on the line 2. No stopcock in continuous infusion system 3. System should be clearly labeled “Epidural Infusion” 4. No other drugs to be injected into the epidural analgesia line 5. Infusion to be altered by anaesthetists only 6. Separate intravenous assess must be available up to at least 4 hours after cessation of epidural infusion Drug Chart 1. Check that prescription for CEI drug refilling is charted. If not, inform Pain Team. 2. Check that anti-emetic P.R.N. is prescribed. 3. No co-analgesics, other opioid analgesia or central depressant is allowed during the use of CEI except prescribed or agreed to by Pain Team. 4. Supplementary oxygen should be given to all patients on CEI for the first 24 hours or as ordered by anaesthetist until reviewed by pain team. Charting of Observation Use Acute Pain Service Observation Chart. Observations should be made hourly until reassessed by the pain team for: apsguide/3/04 74 Blood pressure and Pulse SPO2 in major postop. cases or as indicated Urine Output, CVP if catheters present Pain Score Sedation Score Respiratory Rate Leg weakness Refilling of Drugs for Epidural Local Anaesthetic Infusion Preparation of drugs: Strict adherence to aseptic techniques is important for the prevention of infection. Wash hands before preparing the drugs 3 checks 5 rights with another nurse for all drugs and dilution when mixing the drugs as prescribed in the “As required” column of the drug chart The drug mixture should be added to a 250 ml bag of normal saline as charted Usual continuous epidural infusion prescription: Use a 250 ml bag of normal saline, add i. Bupivacaine 0.5% 60 ml (300 mg) ii. Fentanyl (50 mcg/ml) 16 ml (800 mcg) This 326 ml mixture will give Bupivacaine 0.1% + Fentanyl 2.5mcg/ml (0.00025%) NB: some patients may be using Ropivacaine instead of Bupivacaine: i. Ropivacaine 1% 40 ml (400 mg) ii. Fentanyl (50 mcg/ml) 16 ml (800 mcg) This 306 ml mixture will give Ropivacaine 0.13% + Fentanyl 2.6 mcg/ml Label the bag of drugs - fluid mixture clearly After mixing the drug, aspirate air form the bag of fluid or drug mixture Reset total cassette volume to: 320 ml for Bupivacaine-Fentanyl mix, and 300 ml for Ropivacaine-Fentanyl mix Check pump programme is not cleared or altered Connect the drug mixture to the spike of the pump at one end and make sure that the extension from the pump is connected to epidural filter Recheck for any loose connections and the right infusion rate before restarting the infusion apsguide/3/04 75 Chart “Refilling of drugs” on the patient drug chart Discard epidural mixture after 48 hours if not finished and change to a new bag Resetting total cassette volume This volume fixes the total volume that the pump will infuse. It should correspond to the volume of the drug mixture in the fluid bag. When the volume of the bag is low, the pump will alarm and notify the user that the volume of drug is low, and that the bag of drug mixture will need refilling or changing. The pump will then switch to a preset ‘Keep vein open’ (KVO) rate at 1 ml/hour until the bag of drug is refilled and the cassette volume reset. Hence each time a new bag of drugs is put up, this volume has to be readjusted. You will need the access code to change the cassette volume. Please refer to the above quick reference guidelines. Stopping continuous epidural infusion The pain team usually stops the continuous epidural infusion when satisfactory pain relief is achieved by oral analgesic medication or as the pain improves with healing after a few days. When epidural infusion is stopped, please make sure that parenteral and/or oral opioid analgesia is prescribed on the “As Required” column of the drug chart. Please return the epidural infusion pump to OT recovery room as soon as possible. Discard the remaining opioid drugs. Inform Pain Team if pain is poorly controlled by parenteral opioid after stopping CEI. The pain team will review the patient again if necessary. Contact Pain Team Pager 1067 / DECT phone 6172 for any query. apsguide/3/04 76 NURSING GUIDELINES – MONITORING AND SIDE EFFECTS Although postoperative PCA or CEI analgesia are effective and improve patient recovery and satisfaction, side effects of therapy may occur. Nausea, vomiting, pruritis, urinary retention as well as sedation and respiratory depression may occur with opioid use and hypotension, paresthesia and leg weakness may occur with epidural analgesia. When a patient is on PCA or continuous epidural infusion, he must be monitored closely especially for the first 24 hr during the recovery from general anaesthetic. For the safe and effective analgesia, several parameters must be monitored: 1. Vital signs - Hourly BP, Pulse rate, (Urine output, SpO2, CVP in critically ill cases) 2. Pain chart - Pain score, sedation level, respiratory rate, leg weakness (for epidural analgesia) 3. Side-effects - Nausea, vomiting, pruritis, paresthesia Most of the side effects can be treated by the following drugs. If the side effects are not relieved and the patient remains distressed, you should inform the pain team for reassessment. Reducing the dose of opioid or local anaesthetic may help. Treatment Nausea, vomiting Metoclopramide 10mg q6h p.r.n. iv/im/orally, other antiemetics eg prochlorperazine, ondansetron, droperidol, or change/stop opioid Pruritis Chlorpheniramine 5 mg iv/im, 4mg orally, or change/stop opioid Paraesthesia Reduce LA infusion rate or LA concentration, or stop LA infusion Leg weakness Reduce LA infusion rate or LA concentration, or stop LA infusion Urinary retention Urinary catheter Hypotension Stop LA infusion, iv fluid bolus or metaraminol (vasoconstrictor) Sedation Reduce opioid dose, naloxone 0.1 mg boluses Resp. depression Reduce opioid dose, naloxone 0.1 mg boluses apsguide/3/04 77 Note: Ensure that no other sedative drugs are being prescribed without approval of the pain team. Ensure only the patient pushes PCA button (except in the case of nurse controlled analgesia) Inform pain team Pager 1067 / DECT phone 6172 when in doubt or adverse effects not responsive to treatment apsguide/3/04 78 PCA Nursing Standing Order Oxygen supplement For 24 Hr Vital signs - Hourly BP, P, Urine output, SpO2 Pain chart - Pain Score, Sedation Level, RR Inform Pain Team (pager 1067 / DECT phone 6172) if 1. Inadequate pain relief, pain score > 3 2. Drowsy or over-sedated 3. Respiratory rate < 10/min 4. Abnormal vital signs eg hypotension, low urine output, SpO2 5. Severe nausea & vomiting, itch 6. Unrelieved PCA alarms Crisis If patient is 1. Un-arousable 2. Respiratory rate < 8/min 3. Apnoeic or respiratory obstruction 4. Severe hypotension (< 80/40) Management 1. Immediately notify any medical staff that may be on hand 2. Call the switchboard (ext.2468) and advise of an arrest call. Then page the Pain Team (pager 1067 / DECT phone 6172). 3. Administer oxygen via a tightly applied Ambu bag 4. If a patient has no respiration, administer Narcan (naloxone)IV: 0.1 mg. This may be repeated within minutes if there is no response. apsguide/3/04 79 Epidural Infusion Nursing Standing Order Oxygen supplement For 24 Hr Vital signs - Hourly BP, P, Urine output, SpO2 Pain chart - Pain Score , Sedation Level, RR, Paraesthesia, Leg weakness Inform Pain Team (pager 1067 / DECT phone 6172) if 1. Inadequate pain relief, Pain score > 3 2. Drowsy or over-sedated 3. Respiratory rate < 10/min 4. Abnormal vital signs eg hypotension (< 90/40), low urine o/p, SpO2 5. Severe nausea & vomiting, itch 6. Leg weakness or numbness is present Crisis If patient is 1. Unarousable 2. Respiratory rate < 8/min 3. Apnoeic or respiratory obstruction 4. Severe hypotension (80/40) Management 1. Immediately notify any medical staff that may be on hand 2. Call the switchboard (ext.2468) and advise of an arrest call. Then page the Pain Team (pager 1067 / DECT phone 6172). 3. Administer oxygen via a tightly applied Ambu bag 4. If a patient has no respiration, administer Narcan (naloxone)IV: 0.1 mg. This may be repeated within minutes if there is no response. 5. If hypotension, give colloid 250 ml stat. Have available metaraminol. apsguide/3/04 80 USEFUL NUMBERS Useful telephone extension numbers: Resuscitation 2468 Department Anaesthesia & Intensive Care Main Office 2735 ICU 3026/3027 Operating Theatre Control 2527/2534 Recovery room 2532/2533 Useful hospital pager numbers Duty Pain MO 1067 (24 hr) Pain Nurse (DECT phone) 6172 (Mon-Fri: 0800-1600) (Sat: 0800-1200) Duty Obstetric Anaesthesia MO 1068 (24 hr) ICU MO 1050 ICU senior 1065 OT MO 1054 OT senior 1040 apsguide/3/04 81