Postgraduate Admission requirements for the Postgraduate programmes in the Department of Life and Consumer Sciences 2014/2015 intake Department Qualification Contact details for the Department of Life and Consumer Sciences Department of Life and Consumer Sciences Masters of Life Science Enquiries:Ms Van Wyk for all applications to the Master in Consumer Science programme Generic email will be created. Prof PT Matjila, Postgraduate Coordinator for the Master in Life Sciences programme, Tel: +27 11 471 2730 Email: matjipt@unisa.ac.za Curriculum: A research proposal module (MPLCS90) and a dissertation (DFCON90). Students are required to first register and comply with the requirements for completion of the research proposal module and ethics application before registration for the dissertation will be allowed. The purpose of this module is for students to gain the knowledge and skills required to execute a research project that falls within the scope of the research groups particular to d Life and Consumer Sciences. The learner accredited with this module will be able to: Identify a research problem Formulate the problem, research questions and/or set appropriate hypothesis Set well defined research objectives Compile a literature review Present a suitable methodology and data analysis for the research project 25 Purpose of Research Proposal Module: MPLCS90 Application dates Admission requirements for the MPLCS90 module Selection procedure Identify the contribution the research will make Draft a research proposal that addresses all of the above Students interested in the Master in Life Science program need to apply during the bulk application dates of Unisa which are from 15 September to 15 November 2014 for 2015 admission. Admission to Master's studies is dependent on the candidate being in possession of a Bachelor of Honours degree (or equivalent) in any of the Life Sciences fields. A student who is admitted on the strength of an equivalent qualification and who has not completed a module in research methodology may be required to complete such a module at NQF level 8 for non-degree purposes (NDP) before he/she will be allowed to register for the research proposal module. An approved selection procedure which is in line with Unisa’s policies and equality and diversity in the discipline or department will be implemented. The following selection procedure will be applied: All students are required to first choose a qualification within the College of their choice All applicants are required to apply for a student number first Students are then required to apply for admission and provide the required supporting documents Administrative verification will take place whereby students will be informed if any documentation is outstanding Application should reach the student admission office no later than 15 November The application will be forwarded to the Postgraduate Coordinator for the Master in Life Science programme via myUnisa in the Department of Life and Consumer Sciences for consideration A selection committee consisting of the Research group leaders particular to this programme, supervisors in the Life Sciences discipline and Postgraduate Coordinator for the Master in Life Sciences will complete the review process of the application by 15 January 2015 In cases where clarity is required on the application the Postgraduate coordinator may consider requesting an interview (telephonic or in person) with the candidate Applications of selected candidates will be forwarded to the College Office for 26 Procedures for unsuccessful applications Documents to support application Research and Graduate Studies where-after the selected applications will be forwarded to the College Research Innovation and Higher Degrees committee for final approval Successful candidates will be notified by the M&D section who will then assist with further registration for the Research Proposal Module. Candidates who were unsuccessful may apply to the Postgraduate Coordinator for the Master of Life Science programme for the reasons for rejection of the application. All appeals will be considered by an appeal committee consisting of the Head of the College Office for Research and Postgraduate Studies, Director for the School of Agriculture and Life Sciences, Chair of the Department of Life and Consumer Sciences and members of the Research Committee of the Department of Life and Consumer Sciences The outcome of the appeal will be submitted to College management for approval A further appeal may be submitted through the appropriate Unisa procedures. In addition to the admission requirements, ALL applicants must submit the following documentation: A transcript or an academic record, A 4 page PDF concept document describing their intended research according to the project details and descriptions provided on the departmental website. Selection criteria The Departmental Selection Document Form 1 An updated CV Students will be accepted on the following criteria as will be evaluated in the template provided: Applicant information provided Suggested research focus Research proposal evaluation If a 1 is scored for supervisor capacity (8) in the selection criteria document the application will not be considered for admission. 27 Alignment to Enrolment plan 2015 The admission of Master in Life Sciences students are aligned to the 2015 Enrolment plan developed by the Department of Life and Consumer Sciences New intake for 2015 Motivation for intake The Enrolment plan for 2015 was designed to accommodate 24 new students in the Master of Life Science programme for 2015. The selection committee will select 40 students from the applications received. Depending on the number of applicants, an additional 16 students will be placed on a secondary list in case any of the selected 24 students on the primary list is unable to register. The selection will be based on the number of students who have sent in admission documents to a particular research project for Research Group 1 or in line with the outcome of Research Group 2. Sixteen students who comply with the selection criteria, irrespective of which project or group they fall under will be signed off to register online. The 16 students will be allocated within the two research groups servicing the Master in Life Science programme. The selection committee may not be required to make use of the secondary list of students depending on the number of applications received. The Master in Life Sciences programme will continue a 9% intake in each year. Currently there are 7 senior Life Scientists with PhD’s and 2 Junior lectures with MSc’s that can supervise. Two additional posts at junior and senior lecturer level will be filled in the current year. There is enough capacity within the department to supervise students within the focus groups. Alignment of intake to Research Groups Applicants will be required to align the proposed research they will be presenting in the 4 page PDF document to any one of the research projects stipulated in the research group. The proposed research should be developed within the broad context of the research project. Name of the Research Group 1 OMICS Team leader of Research Group Prof PT Matjila Team members of Research Group Team members Specialization of Team member Prof PT Matjila Molecular parasitologist 28 Goal and Purpose of the Research Group Key focuses of the Research Group Motivation for the number of students accommodated in this Research Group for 2015 Prof J Dewar Microbiologist/virologist Dr S Gildenhuys Biochemist/proteomics Dr N Parbhoo Biochemist/proteomics Prof Z Dlamini Molecular biologis Dr Z Mbita Molecular biologist Dr G Prinsloo Metabolomics Dr R Hull Molecular biologist The focus of the Omics group will be to advance research in the development of improved diagnostics and therapeutics using molecular approaches. The group will focus on the development and application of tools using advanced second and third generation DNA sequencing technologies, and genotyping platforms for the rapid generation of high resolution genetic maps of important plant, animal and human pathogens. These can be used for the identification of variation in candidate genes in regions of genetic significance to traits of importance in agricultural, veterinary and human health. Extreme emphasise will be placed on research that is of a collaborative effort in nature, with a multidisciplinary approach to tackle all aspects of the research and management of important pathogens afflicting plants, animals and humans. Diagnostics, Therapeutics, Vaccine development, Bioinformatics Following the prescription of the enrolment plan for 2015 only 16 new students will be admitted to research projects in this research group. The number of students will also be determined by the availability of additional spaces within the capacity of a supervisor depending on changing circumstances. This may mean that a supervisor will be able to take more students than the enrolment numbers allocated to the group. The enrolment number may also be determined by the number of applications received which may be fewer than required. The selection committee will determine the circumstances for selecting more or fewer students depending on unplanned changes to the profile of the available supervisors. Therefore the number of students indicated in the capacity column of each project indicates the maximum number of students that will be taken in as the admissions may only be for one specific project and not for any other projects. In instances where there are admissions for different projects the number of applications will be considered and the number in brackets in the capacity column will be accepted. 29 Research Projects in the Research Group 1 Master’s or Doctoral level capacity Master’s Possible supervisor Project name: Expression and characterization of rotavirus capsid protein VP6 Project name:Analysis of Analysis Babesiarossitransciptome for evaluating potential disease outcomes Project name: Project name: Development of recombinant vaccine for the control of both the tick vector and Babesia parasite Project name: The occurrence of tick-borne pathogens in canines in the Western Cape rescue organizations and townships Project name:Development of a Rapid Diagnostic Kit (RDK) for the detection of Babesiarossi in dogs Masters Master’s/PhD Dr S Gildenhuys Dr N Parbhoo Prof Matjila Master’s/PhD Prof Matjila Master’s Prof Matjila Master’s Prof Matila Project name: Genotyping analysis of rotavirus in South Africa Expression and characterization of rotavirus capsid proteins Master’s Prof J Dewar Dr S Gildenhuys Ms L Theron Project name: Molecular characterization of Rotavirus Prof J Dewar Dr S Gildenhuys Research group 2 Name of Research Group 2 Team leader of Research Group Team members of Research Group Phytochemistry and Medically Active Plant Compounds Prof J Dewar Team members Dr MA Nyila Specialization of Team member Phytochemistry 30 Ms I Setshedi Prof SR Magano Prof Matjila Dr S Lebelo Dr T Van Eeden Mrs E Symington Prof R Hendrick Goal and Purpose of the Research Group Key focuses of the Research Group Motivation for the number of students accommodated in this Research Group for 2015 Phytochemistry Phytochemistry Animal parasites Physiology Dietetics Dietetics Water analysis Ms K De Bruyn Water analysis Mr G Prinsloo Animal health Our Department is currently involved in research with the CSIR involving the isolation, identification and bio-assaying of anti-malarial and anti-cancer compounds from plants such as SutherlandiafrutescensandSceletiumtortuosum, respectively. Potential MIT expansion together with researchers from the Department of Environmental Sciences involves the phytoremediative development of wetlands to reduce pollution levels in surface water and with researchers from the Department of Agriculture and Animal Health where plant extracts may be used to treat parasitic infestations of domestic animals. Dietitians, including the Department’s Dr van Eeden and Mrs Symington, may provide valuable insights into essential plant compounds necessary in one’s diet, the role these play in preventing debilitating chronic diseases of lifestyle and the negative impact of dietary deficiencies on the growth and development of our children. Phytomedicine, antimalarial compounds, anti-cancer compounds, antiparasitic compounds Following the prescription of the enrolment plan for 2015 only 16 new students will be admitted to research projects in this research group. The number of students will also be determined by the availability of additional spaces within the capacity of a supervisor depending on changing circumstances. This may mean that a supervisor will be able to take more students than the enrolment numbers allocated to the group. The enrolment number may also be determined by the number of applications received which may be fewer than required. The selection committee will determine the circumstances for selecting more or fewer students depending on unplanned changes to the profile of the available supervisors. Therefore the number of students indicated in the capacity column of each project indicates the maximum number of students that will be taken in as the admissions may only be for one specific project and not for any other projects. In instances where there are admissions 31 Research Projects in the Research Group 2 Project name: Screening of plants or plantbased products for medicinal properties Project name: Mycobacterium tuberculosis kinases: The development of a novel phytochemistry screen for Pelargonium sidoides plan Project name: Determining the effect of processing on the microflora of leaves of Cowpea, a naturalised, edible South African plant Project name: Screening of plants or plant-based products for anti-arthropod properties Project name: Water analysis for different projects the number of applications will be considered and the number in brackets in the capacity column will be accepted. Currently there exists a wide range of projects that fall within extraction of compounds from plant species such as SutherlandiifrutescensandSceletiumtortuosumfor different applications for anti-malaria, anti-cancer and anti-ecto parasites. For specifics on these projects kindly contact the group leader Prof J Dewar (email: dewarj@unisa.ac.za) Master’s or Doctoral Possible supervisor level capacity Master’s/Doctoral Dr MN Nyila Dr M Myer Dr SL Lebelo Ms I Setshedi Mr AR Mudau Mrs EA Symington Dr van Eeden Master’s Prof Dewar Master’s Prof Dewar Master’s/Doctoral Prof SR Magano Master’s/Doctoral Prof R Hendrick Ms K De Bruyn Research group 3 32 Name of Research Group 3 Team leader of Research Group Translational Genomics and Drug Discovery Group Prof Zodwa Dlamini (Molecular Medicine and Functional Genomics) Team members of Research Group Team members Specialization of Team member Dr Zukile Mbita Molecular Genetics Prof Fhatuwani Mudawu Horticultural Management practices Dr Monde Nyila Microbiologist Dr Rodney Hull Molecular and Cell Biology MrSydwel Mukhadi Molecular Genetics Ms Nonkululeko Mthembu Molecular and Cell Biology Mr Sydwell Mukhadi Biochemistry In collaboration with Universities of Bristol and Nottingham-UK, FreieUniversität BerlinGermany, theLudwig Boltzmann Institute for Cancer-Austria, Federal University of Rio de Janeiro-Brazil, Regina Elena Cancer Institute-Rome, ARC Biotechnology Platform-SA, Wits University-SA, University of Vienna Medical School-Austria, the group uses “Translational Medicine and Functional Genomics” technologies including the use of bioinformatics to provide unprecedented possibilities to identify the underlying molecular basis of many common diseases including cancer, and HIV/AIDS. The group aims at contributing new information on how the unique genetics signatures of an individual influence the risk and prognosis of disease. This will be the basis for future individualized medicine in the years to come. Identifying natural products that target and regulate the splicing and the angiogenesis machinery, molecular pathways will be pivotal for new drug discovery. This will be the basis for future individualized medicine in the many years to come because such novel chemical structure can serve as lead compounds for the design and development of new drugs. This group will soon embark on preclinical work involving molecular imaging backed by the Ludwig Boltzmann Institute of Cancer in Vienna-Austria and the Universities of Nottingham and Bristol in the UK and will develop expertise locally using the DST Preclinical Drug Development Platform hosted by the MRC and the Northwest University. Goal and Purpose of the Research Group Key focuses of the Research Group Motivation for the number of students accommodated in this Research Group for 2015 Translational medicine, Bioinformatics, angiogenesis and anti-cancer angiostatic activities, anti-cancer spliceogenomics, HIVAN, Phytomedicine, functional genomics Following the prescription of the enrolment plan for 2015 only 10 new students will be admitted to research projects in this research group. The number of students will also be 33 Research Projects in the Research Group 3 determined by the availability of additional spaces within the capacity of a supervisor depending on changing circumstances. This may mean that a supervisor will be able to take more students than the enrolment numbers allocated to the group. The enrolment number may also be determined by the number of applications received which may be fewer than required. The selection committee will determine the circumstances for selecting more or fewer students depending on unplanned changes to the profile of the available supervisors. Therefore the number of students indicated in the capacity column of each project indicates the maximum number of students that will be taken in as the admissions may only be for one specific project and not for any other projects. In instances where there are admissions for different projects the number of applications will be considered and the number in brackets in the capacity column will be accepted. Currently the following projects are available within this group: 1] Targeting the abnormal MicroRNA and Splicing Signatures in HIVAN and Cancer. 2] Exploiting disease-specific molecular “signatures” with natural products that may serve as novel drugs or lead compounds in the treatment of Cancer, HIVAN and secondary Fungal and bacterial infections. 3] Targeting the aberrant splice variants in cancer. 4] Exploiting the angiostatic activities of natural products for drug discovery. 5] Exploiting natural products in influencing anti-angiogenesis by manipulating the RNA splicing machinery. For specifics on these projects kindly contact the group leader Prof Zodwa Dlamini (email: dlamizl@unisa.ac.za) Project name: MicroRNAs (miRNAs) profiling in Human Immunodeficiency Virus-1 Associated Nephropathy (HIVAN) Master’s/PhD Prof Z Dlamini Dr R Hull Project name: Exploiting of South African Medicinal plants for anti-cancer/angiostatic activities Project name: Regulation and function of RBBP6 isoform 3 in cell cycle and carcinogenesis Master’s Prof Z Dlamini Dr R Hull Master’s/PhD Dr. Z Mbita 34 Research Proposal module details All research projects listed above feed directly into the development of the research proposal MPLCS90 for which students will register if they have been successfully admitted to the Master of Life Sciences. Assessment mode for MPLCS90 The research proposal will be assessed through the use of an assessment template consisting of key assessment categories that pertain to a research proposal Assessment criteria for Research proposal The assessment of the research proposal will be conducted as follows: A vetting committee consisting of the Research Committee in the Department of Life and Consumer Sciences consisting of the following profiles (senior staff members and/or may have NRF rating and/or are supervisors or co-supervisors of students and/or have examined research proposals before and/or have been requested to do act as an external examiner for other universities) will veteach research proposal The proposal will also be vetted by two appropriate internal departmental experts of which one should at least be familiar with the field of research. The supervisor is required to be present at the vetting committee meeting The vetted proposal will then be considered at a Departmental Vetting committee meeting Verbal feedback will be given to the supervisor and the template on which the comments were documented will be returned to the supervisor in order to amend the proposal where necessary If the proposal is approved, the student and supervisor will receive a letter of approval from the COD Assessment criteria for Research Proposal for Master in Life Sciences Mode of delivery of MPLCS90 Online delivery will be followed through means of study units on myUnisa, discussion forums and the submission of two assignments on myUnisa related to the research proposal. Video conferencing sessions may be organised by the post graduate programme coordinator for all Master students in the department of Life and Consumer Sciences 35 Mode of supervision for MPLCS90 External supervision Collaboration A seminar may also be organised for the presentation of completed research proposals which may be delivered through video conferencing or on the Florida campus Supervision may be delivered in different modes depending on the requirement of the supervisor and study design: One-on-one contact sessions may be required which can be delivered through video conferencing for students in remote areas or through personal visits to the supervisor if the student is able to visit the Florida Campus Email contact on a personal basis to assist in addressing student queries will be the main mode of delivery Track changed documents or pdf scanned documents in which the supervisor has made corrections or provided suggestions will be used. Should the need arise to include an external supervisor the decision will be made based on the expertise or assistance required from an external supervisor on a particular part of the project. This will only be implemented if the internal capacity of supervision cannot support the requirement of the research project. Students undertaking research outside the borders of South Africa must be allocated an external supervisor/co-supervisor that is knowledgeable, or resides in the area in which the research is undertaken. Students are welcome to identify possible external supervisors, however, the selection and appointment of these external supervisors remains the responsibility of the Department of Life and Consumer Sciences. The Department of Life and Consumer Sciences has collaborative agreements with the following institutions: i. Council for Scientific and Industrial Research (CSIR) ii. Agricultural Research Council iii. Medical Research Council iv. The University of the Witwatersrand (Wits) Where relevant, a student may be placed in collaborative research with any of the above institutions. 36