Supplementary information 1 Study centers, site investigators, and coordinators for the International EECP Patient Registries 1 and 2 IEPR-1: United States: Alabama: Southeastern Cardiology Consultants P.C., Montgomery, Kenneth Wool, MD, Donna Deason, RN; The Heart Center, Huntsville, J. Michael Campbell, MD, Jewell Owens, LPN; The Heart Center, P.C., Decatur, James D. Murphy, MD, Tanya Rea, LPN; Arkansas: Baptist Medical Center, Little Rock, Kimber Stout, MD, Diana Emfrey, RN; Central Arkansas Cardiology, N. Little Rock, Charles Caldwell, MD, Carrie Limberg, LPN; Heartcare Clinic of Arkansas, Little Rock, Charles P. Fitzgerald, MD, Barbara Wall, RN; Arizona: Advanced Cardiac Specialists, Gilbert, Robert Siegel, MD, Mike Wolver; Cardiac Solutions, Peoria, Joseph Caplan, MD, Brian Kilpatrick; Heart Institute of Northern Arizona, Kingman, A. Paul Kalanithi, MD, Jason Mastin; HeartGen-Arizona, Scottsdale, Michael Eads, MD, Caroline Thomas, RN; Southwest Heart, Tucson, Brenda Peart, MD, Janet Browne, CMA; California: Cardiac Renewal Centers - Oceanside, Oceanside, Franklin Murphy, MD, Jennifer Deyo; Cardiac Renewal Centers Palm Desert, Palm Desert, Franklin Murphy, MD, Keith Gibson; Ocean View Medical Group, Inc., Santa Monica, Monroe Rosenthal, MD, Martin Turner, BS; UCSD Medical Center, San Diego, Ori Ben-Yehuda, MD, Lisa Stocks, RN; UCSF-Mount Zion Medical Center, San Francisco, Gordon Fung, MD, Dorothy Ruggles-Stern, RN; Whitaker Wellness Institute, Newport Beach, Allan Sosin, MD, April Gregg, LVN; Colorado: Kaiser Permanente, Denver, David Flitter, MD, Ami Hennen, RN; Florida: Cardiology and Medicine Associates, Inc., Vero Beach, Nancy R. Cho, MD, Joanne Giordano, LPN; Dimitri C. Pyrros, MD, PA, Margate, Dimitri C. Pyrros, MD, Scott Elrod, EMT; JFK Medical Center, Atlantis, Norman Erenrich, MD, Angelica Patten, RN; Miami Heart Institute, Miami Beach, Kevin Coy, MD, Dania Tabares, RCVT; Neurology & Cardiology, Associates, Hollywood, Jonathan Jaffe, MD, Laurie Sanders; Shands Hospital, Gainesville, C. Richard Conti, MD, Karen Owens, LPN; South Florida Cardiology Associates, Pembroke Pines, Perry Krichmar, M.D., Lizzett Perez; Georgia: Cardiac Disease Specialists, Atlanta, Harvey Sacks, MD, Clarice Stevenson; Perennia Heart Centers, Norcross, Matthew Britton, MD, Pauline Cooke, RN; Iowa: Mason City Clinic, Mercy Heart Center, Mason City, Samuel J. Congello, DO, Heather Miller, RN; St. Luke's Regional Medical Center, Sioux City, Kenneth Tjeerdsma, MD, Emily Hammett, CBT; Illinois: Christ Hospital and Medical Ctr., Oak Lawn, Marc Silver, M.D., Carol Pisano, RN, BSN; North Suburban Cardiology Group, Ltd., Arlington Heights, Edward Pinsel, MD, Laura Clemens, RN; Indiana: HeartGen-Midtown, Indianapolis, Georgiann Linnemeier, MD; HeartGen-North, Indianapolis, Georgiann Linnemeier, MD; Helix Health Centers, Carmel, Georgiann Linnemeier, MD; Indiana Cardiac and Vascular Consultants, Indianapolis, Georgiann Linnemeier, MD, Leandra Newton, MA; The Angina Center at Ohio Valley Heart Care, Evansville, Ralph Millsaps, MD, Joseph Winterman, RN; Kansas: Cotton O'Neil Heart Center, Topeka, Thomas Doyle, MD, Amy L. Baker, RN; Louisana: Ochsner Foundation Hospital, New Orleans, Mandeep Mehra, MD, Greta Alaimo, LPN; Uptown Heart Center, New Orleans, John R. Cook, MD, Gina Caronna, RN; Massachusetts: The Cardiovascular Specialists, LLC, Falmouth, Bruce F. Levy, MD, Tracy Leitao, RN; Maryland: Howard County General EECP Lab, Columbia, Harry A. Oken, MD, Gladys M. Curley, BS, CPT; Shady Grove Adventist Hospital Cardiac Rehab, Rockville, Dennis Friedman, MD, Gail Driskill, RN; Maine: Central Maine Medical Center, Lewiston, Mark Lanzieri, MD, Carol Domingue, RN; Michigan: Borgess Health and Fitness Center, Kalamazoo, Alicia Williams, DO, Julie Johnson, MA, CES; Minnesota: Hennepin County Medical Center, Minneapolis, Brad Bart, MD, Kim LaNasa, MA, EP; Mayo Clinic, Rochester, Gregory Barsness, MD, Linda Tesmer, RN; Missouri: Cardiovascular Specialists, Springfield, Paul Freiman, MD, Suzan Johnson, RN; Independence Cardiology Associates, Independence, Paul R. Chu, MD, Susan Sorensen; Missouri Heart Center, Columbia, James Elliott, MD, Jeanette Quick, CMA; Nebraska: Nebraska Heart Institute, Lincoln, Steve K. Krueger, MD, Pat VerMaas, RN, MSN; New Jersey: Cardiology Associates, West Paterson, Anthony Losardo, MD, Danielle Doyle, RN; EECP Heart Center of NJ, Old Bridge, Gerald Weisfogel, MD, Jewel Shanahan, CMA; Monmouth Cardiology Associates, Freehold, Mark Rosenbloom, MD, Michael Perez, RN; Our Lady of Lourdes Medical Center, Camden, Jan R. Weber, MD, Cheryl Marks, RN, CCRN; The Heart & Vascular Institute, Morristown, Morey Klein, MD, Debbie Milkosky, RN; The Heart-Lung Center, Hawthorne, John Strobeck, MD, Robin Reade, RN; Total Cardiology Care, Jersey City, Mitchell Baruchin, MD, Barbara Skokowski, RN; University of Medicine & Dentistry of New Jersey, Newark, Rohit Arora, MD, Tim Smith; Nevada: EECP Center of Nevada, Las Vegas, Matthew J. McMahon, DO, Kathleen Sponseller, RN; New York: Albany Associates in Cardiology, Albany, Michael Marmulstein, MD, Anne Marie Carey, RN; Ash Heart Center, New York, John Strobeck, MD; Cardiology Associates, Johnson City, Richard Ryder, MD, Deborah Norris, RN; Cardiology Associates of Brooklyn, Brooklyn, Norbert Moskovits, MD, Ginger Mars, RN, NP; Columbia Presbyterian Medical Ctr, New York, Rohit R. Arora, MD, Nicole Baron, BS; EECP of Nassau, Valley Stream, Edward T. Davison, MD, Diane Bonagura, RN; Heart Associates of the Finger Lakes, Newark, Frederick Zugibe, MD, Anna R. Zugibe; Integrated Cardiovascular Therapeutics, Woodbury, Ronnie A Hershman, MD, Debra A. Chalmers, NP; New York Heart Center, Syracuse, Eugene C. Lozner, MD, Norma Phuntek, LPN; New York United Hospital, Port Chester, Joseph Tartaglia, MD, Barbara DiLeo, RN; Staten Island Heart, Staten Island, James Lafferty, MD, Laura Ferrara, RN, CRN; SUNY Stony Brook, Stony Brook, William E. Lawson, MD, Denise F.O. D'Ambrosia, RN; The Atkins Center of Complimentary Medicine, New York, Patrick Fratellone, MD, Gail Walls, CVT; The Cardio-Pulmonary Continuum, Manhasset, Perry A. Frankel, MD, Leah Cervantes, RN; Ohio: Associates in Cardiovascular Medicine, Westerville, Jack Stanko, MD, Brett Elliott, BS; Cardiovascular Research Institute, Columbus, Bruce Fleishman, MD, Karen Manzo, RN; Cleveland Clinic Foundation, Cleveland, Stephen Ellis, MD, Rosemary Kidd, RN; EECP Center of Northwest Ohio, Toledo, James C. Roberts, MD, Jean French, MA; Ohio Heart Health Center, Cincinnati, Charles Abbottsmith, MD, Sandy Metze, EMT-P; Oklahoma: Cardiovascular Clinic, Div. of Plaza Medical Group, Oklahoma City, Jerry L. Rhodes, MD, Sheryl Sallee, CRT, RCP; Oregon: Heart Centers of America, Portland, Ronald Schutz, MD, Brenda Rantala, RN; Pennsylvania: Brookville Hospital, Brookville, Jivan Patel, MD, Dana Smith, LPN; Consultants in Cardiovascular Disease, Erie, William L. Mecca, MD, Sue Simon, RN; EECP Center of Pittsburgh, Pittsburgh, Thomas Pinto, MD, Louanne Tempich, LPN; University of Pittsburgh Medical Center, Pittsburgh, Ozlem Soran, MD, Renee Litrun, CVT; UPMC - Century Cardiac Care, White Oak, Daniel Jovanovich, MD, Dawn Streussnig; Vital Heart, Philadelphia, Debra L. Braverman, MD, Jenifer Arroyo, RN; York Hospital Cardiac Rehab, York, Kevin McCullum, MD, Maureen Izer, RN; Rhode Island: South County Cardiology Assoc, Wakefield, Neil Brandon, MD, Elizabeth Laffey, RN; South Carolina: South Carolina Heart Center, Columbia, Michael Foster, MD, Tracy Canter; South Dakota: Chandra Cardiovascular Consultants, Dakota Dunes, Yunus Moosa, MD, Deanna Bennett, RN; Tennessee: Knoxville Cardiovascular Group, Knoxville, Stuart Bresee, MD, Teresa Boling, CMA, CRT; Texas: Advanced Heart Care, Paris, Jeffrey R. Gladden, MD, Diane James, CVT; BCS Heart, College Station, W. Richard Cashion, Jr, MD, Mallisa Karonka, LVN; Virginia: EECP Center of Northern Virginia, Reston, Kenneth Brooks, MD, Elizabeth J. La Rose, RN; EECP of Northern Virginia, Fairfax, Kenneth M. Brooks, MD, Trudy Waldron, LPN; Riverside Regional Medical Center, Newport News, Allan Murphy, MD, Theresa Daoud, RN; University of Virginia, Charlottesville, George Beller, MD, Ellen Longmoore, CNMT; Vermont: Integrative Cardiology, Rutland, Bart Bonazinga, MD, Judy Long, RN, BSN; Wisconsin: Cardiovascular Assoc. of Northern Wisconsin, Wausau, Paul Luetmer, MD, Arlyne Frane, RN; ARUBA: Aruba Heart Institute & Medical Center, Oranjestad, C.F.Lacle, Julienne Garcia; BAHAMAS: Lyford Cay Hospital, Nassau, C. Dean Tseretopoulos, MD, Indera Stubbs, RN; COLOMBIA: Fundacion Clinica Shaio, Bogota, Daniel Isaza-Restrepo, MD, Susana Reyes; IRELAND: Beaumont Hospital, Dublin, Angie Brown, MD, Fa'in'sia Mee; ISRAEL: Cardiomore, Tel-Aviv, Ilan Or, MD, Yosefi Haim, MD; SAUDI ARABIA: Al-Mostaqbal Hospital, Dr. Gentang Cui, Dr. Gentang Cui; TURKEY: Medkar Heart Center, Ankara, Ozlem Soran, MD, Ferruh Yavuz, MD; UK: Hammersmith Hospital, London, Peder Bagger, MD, Kostas Kiryakis; Hull Royal Infirmary, Hull, John Cleland MD, Huan Loh MD. IEPR-2: Arkansas: Central Arkansas Cardiology, N. Little Rock, Charles Caldwell, MD, Carrie Limberg, LPN; Arizona: Advance Cardiac Specialists - Ironwood, Apache Junction, Robert Siegel, MD, Gina Villa; Cardiac Solutions, Peoria, Joseph Caplan, MD, Brian Kilpatrick, EMT; Heart Institute of Northern Arizona, Kingman, A. Paul Kalanithi, MD, Jason Mastin; HeartGen Centers, Inc., Scottsdale, Michael Eads, MD, Caroline Thomas, RN; Southwest Heart, Tucson, Brenda Peart, MD, Janet Browne; California: Cardiology Associates Medical Group, Inc., Ventura, Siegfried O. Storz, MD, Kim Aquino; Scripps Center for Integrative Medicine, La Jolla, Erminia Guarneri, MD, Eva Stuart, RN; UCSF-Mt Zion Medical Center, San Francisco, Gordon L. Fung, MD, Dorothy Ruggles Stern RN; Connecticut: Griffin Hospital, Derby, Kenneth V. Schwartz, MD, Judy Grenon, RN; Florida: Boca Delray Cardiology, PA, Delray Beach, Bruce Martin, MD, Heather Saunders, MA; Cardiology & Medicine Associates, Vero Beach, Nancy Cho, MD, Joanne Giordano, LPN; JFK Medical Center, Atlantis, Norman Erenrich, MD, Angelica Patten, RN; Stanley Williams, MD, Inverness, Stanley Williams, MD, Melissa Lyons; Tarpon Center for Angina Therapy, Tarpon Springs, Norman Abbott, MD, Dominick Fratello, RN; Georgia: Cardiology Associates, Albany, Steven C. Wolinsky, DO, Kimberly Bryan, LPN; Cardiology Consultants, Thomasville, James Karas, MD, Linda McMath, LPN; HeartGen, Atlanta, Ramona Minnis, MD, Patrick Martin; Iowa: Mercy Hospital Medical Center, Des Moines, William J. Wickemeyer, MD, Donna Gideon; St. Luke's Hospital, Cedar Rapids, Michael Chandra, MD, Deb O'Neil, RN; Illinois: Cardiology Consultants, Ltd., Belleville, Atul S. Shah, MD, FACC, Donna Mann, RN; Christ Hospital and Medical Center, Oak Lawn, Marc Silver, MD, Carol Pisano, RN; HeartGen Center, Des Plaines, Olga Lansky, MD, Ena Jordan; North Suburban Cardiology Group, Ltd., Arlington Heights, Edward Pinsel, MD, Laura Clemens, RN; Indiana: Advanced Angina Center, Jeffersonville, M. Saleem Seyal, MD, Dana Wagner, RN; HeartGen - North, Indianapolis, Georgiann Linnemeier, MD; Indiana Heart Associates, Indianapolis, Don Zipperman, MD, Shawna Toombs, EMT; The Angina Center of Evansville, Evansville, Ralph Millsaps, MD, Joseph Winterman, RN; The Heart Group, Evansville, Jerry Becker, MD, Lori Hunt, RN; Kansas: Wichita EECP Heart Center, Wichita, Roger Evans, MD, Linda Rae Hillier, RN; Kentucky: Central Baptist Hospital, Lexington, Pam Gage, RN, Nanette Abrams, RN; Jackson Purchase Medical Center, Mayfield, Tyrone Daniels, MD, Regina Williams, RRT; Massachusetts: Cardiovascular Specialists, Sandwich, Bruce Levy, MD, Mary Cassidy; Granite Medical Group, Quincy, Alan Berrick, MD, Barbara Brangiforte, LPN; Maryland: Shady Grove Adventist Hospital Cardiac Rehab, Rockville, Dennis Friedman, MD, Gail Driskill, RN; Michigan: Borgess Health and Fitness Center, Kalamazoo, Alicia Williams, DO, Julie Johnson; William Beaumont Hospital, Royal Oak, Peter McCullough, MD, Liberty Van Eik; Minnesota: Hennepin County Medical Center, Minneapolis, Brad Bart, MD, Kim LaNasa, MA, EP; Mayo Clinic, St. Mary's Hospital, Rochester, Gregory Barsness, MD, Linda Tesmer, RN; Minneapolis Heart Institute Foundation, Minneapolis, Timothy Henry, MD, Terri Streufert, RN; Missouri: HeartGen - Des Peres, St. Louis, James Nahlik, MD, Melissa Scheer; HeartGen - St. Louis, St. Louis, James Nahlik, MD, Kim Herbert, RN; Missouri Heart Center, Columbia, James Elliott, MD, Jeanette Quick, RN; North Carolina: Wake Heart Associates, Raleigh, R. Lee Jobe, MD, Sharon Knight, RRT; Nebraska: Creighton University Cardiac Center, Omaha, Paul Biddle, MD, Megan McCarthy; New Hampshire: Elliot Hospital, Manchester, Robert Lavery, MD, FACC, Diane Carrier, RN; New Jersey: Bergen Cardiology Associates, Teaneck, David Landers, MD, Debra Roditski, RN; Cardiology Associates, West Paterson, Anthony Losardo, MD, Danielle Doyle, RN; ECP Heart Center of NJ, Old Bridge, Gerald Weisfogel, MD, Jewel Shanahan, CMA; Heart-Lung Center, Hawthorne, John E. Strobeck, MD, Robin Reade, RN; Medical Institute of New Jersey, Cedar Knolls, Leonard Moss, MD, Ellen Pateman, RN; Medicor Cardiology, Bridgewater, Kenneth Sternberg, MD, Luz Vanegas, LPN; Our Lady of Lourdes Medical Center, Camden, Jan R. Weber, MD, Cheryl Marks, RN; Nevada: ECP Heart Centre, Las Vegas, Blaine Purcell, MD, Ambar Faridi; New York: EECP of Nassau, Valley Stream, Edward T. Davison, MD, Diane Bonagura, RN; L.I. Cardiology & Internal Medicine, Massapequa, Michael Sacher, DO, Maureen Matos, RN; Long Island Heart Associates, Mineola, Steven Zeldis, MD, Robert J. Mullan; Staten Island Heart, Staten Island, James Lafferty, MD, Laura Ferrara, RN, CRN; Stony Brook University Hospital, Stony Brook, William E. Lawson, MD, Denise D'Ambrosia, FNPC; Ohio: Associates in Cardiovascular Medicine, Westerville, Andrew P. Klaus, MD, Brett Elliott, BS; Cardiovascular Research Institute, Inc., Columbus, Bruce Fleishman, MD, Karen Manzo, RN; Cleveland Clinic Foundation, Cleveland, Stephen Ellis, MD, Jeanette Mitchell, RN; Northwest Ohio Cardiology Consultants, Toledo, Todd L. Monroe, MD, Diane Philip, RN; Oregon: Heart Centers of America, Portland, Ronald Schutz, MD, Ardys Hawkins, RN; Oregon Cardiology, Eugene, Jay Chappell, MD, Christi Flood; Pennsylvania: Consultants in Cardiovascular Disease, Erie, William L. Mecca, MD, Monica Chase; EECP Center of Pittsburgh, Pittsburgh, Thomas Pinto, MD, Louanne Tempich, LPN; Moffitt Heart & Vascular Group, Wormleysburg, Jeffrey Mandak, MD, Anita Todd, RN; Susquehanna Cardiology Associates, Williamsport, Donald Nardone, MD, Gwen Hill, RN; The Heart Care Group, Allentown, James A. Pantano, MD, Ruth Ann Gerchufsky; University of Pittsburgh Medical Center, Pittsburgh, Ozlem Soran, MD, Renee Litrun, CVT; York Hospital Cardiac Rehab, York, Kevin McCullum, MD, Cindy Yingling, RN; Puerto Rico: Edgardo Bermudez, MD, Ponce, Edgardo Bermudez, MD, Arlene Rivera; South Dakota: Avera McKennan Hospital Cardiovascular/Stress, Sioux Falls, Kevin Vaska, MD, Carol Scholten, RN; Tennessee: Knoxville Cardiovascular Group, Knoxville, Stuart Bresee, MD, Teresa Boling; Virginia: University of Virginia, Charlottesville, George Beller, MD, Ellen Longmoore, CNMT; Washington: The Poly Clinic, Seattle, Timothy Dewhurst, MD, Matt Berger; Wisconsin: Wisconsin Heart, Madison, John Moses, MD, Ramona Van.