M. Suckow, K. Stevens, and R. Wilson, editors, 2012. The Laboratory Rabbit, Guinea Pig,
Hamster, and Other Rodents, 1st edition. Elsevier, Oxford, UK.
Chapter 14 Viral Diseases, pp. 365-413
QUESTIONS
1.
Which of the following viruses was intentionally introduced into Australia, and later
France, in an attempt to control the increasing rabbit pest problem?
a.
Myxoma virus
b.
Rabbit Hemorrhagic Disease Virus
c.
Leporid herpesvirus 1
d.
Bunyavirus
2.
Myxoma virus in rabbits results in a severe, systemic disease in which species:
a.
Lepus tinidus
b.
Sylvilagus braziliensis
c.
Oryctolagus cuniculus
d.
Sylvilagus floridanus
3.
Which of the following contains only intracytoplasmic inclusions?
a.
Myxoma virus
b.
Rabbit Hemorrhagic Disease Virus
c.
Rabbit Oral Papillomavirus
d.
Herpesvirus cuniculi
e.
Rabbit Kidney Vacuolating Virus
4.
Which of the following closely resembles Shope fibromatosis in Sylvilagus species, but
causes a rapid, fatal infection in Oryctalagus species?
a.
Rabbit calicivirus
b.
Myxoma virus
c.
European Brown Hare Syndrome Virus
d.
Shope papillomatosis
5.
Which of the following is a diagnostic distinction between Shope fibromatosis and
papillomatosis in rabbits?
a.
Presence of intranuclear inclusions
b.
Presence of skin tumors
c.
Age of rabbits affected
6.
Which of the following viruses of rabbits in the family Poxviridae is an Orthopoxvirus?
a.
Hare Fibroma Virus
b.
Rabbit (Shope) Fibroma Virus
c.
Myxoma Virus
d.
Rabbit Poxvirus
7.
Indicate whether the following viruses are DNA or RNA viruses:
a.
Rabbit Hemorrhagic Disease Virus
b.
Rabbit Fibroma Virus
c.
Leporid Herpesvirus 1
d.
Rotavirus
e.
Lapine parvovirus
f.
Shope Papillomavirus
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
Which of the following viruses is anthropozoonotic in humans and rabbits?
a.
Poxvirus
b.
Herpesvirus
c.
Papillomavirus
d.
Calicivirus
To what genus does Cottontail Rabbit Papillomavirus belong?
a.
Papillomavirus
b.
Polyomavirus
c.
Kappapapillomavirus
d.
Betapapillomavirus
True or False: Rabbit Oral Papillomavirus is immunologically identical to Cottontail
Rabbit Papilomovirus.
Which of the following in nonpathogenic for all rabbit species?
a.
Rabbit Kidney Vacuolating Virus
b.
European Brown Hare Syndrome Virus
c.
Leporid parvovirus 4
d.
Rabbit Hemorrhagic Disease Virus
True or False: Rabbit Kidney Vacuolating Virus may be a contaminant in rabbit
papillomas, but appear to have no role in the pathogenesis of papillomatosis.
Which of the following is not typically a cause of diarrhea in young rabbits?
a.
Rabbit Hemorrhagic Disease Virus
b.
Rotavirus
c.
Coronaviral enteritis
d.
Colibacillosis
Which of the following is most effective at eliminating rotavirus?
a.
Chlorine
b.
Formalin
c.
95% Ethanol
d.
Betapropriolactone
Which of the following is not a pathologic lesion associated with rotavirus?
a.
Intestines markedly congested and distended
b.
Villous blunting
c.
Mucosal hemorrhages
d.
Proliferative ileitis
True or False: It is possible to rederive rabbits free of rotaviral infection through early
weaning.
Which of the following types of viruses may be a useful model for virus-induced
cardiomyopathy?
a.
Coronavirus
b.
Calicivirus
c.
Parvovirus
d.
Bunyavirus
The “etiologic agents of necrotic hepatitis of leporids” are classified as what type of
viruses?
a.
Calicivirus
b.
Coronavirus
19.
20.
21.
22.
c.
Flavivirus
d.
Herpesvirus
What is the most consistent finding in Rabbit Hemorrhagic Disease Virus?
a.
Pale liver with periportal necrosis
b.
Splenomegaly
c.
Diarrhea
d.
Pulmonary congestion
Which of the following viruses does not result in clinical disease in rabbits?
a.
European Brown Hare Syndrome Virus
b.
Rabbit Calicivirus
c.
Michigan Rabbit Calicivirus
d.
Rabbit Hemorrhagic Disease Virus
Which of the following rat viruses do rabbits develop antibodies to?
a.
Sendai virus
b.
Rat Respiratory virus
c.
Sialodacryoadenitis Virus
d.
PVM
Which of the following species is not involved in perpetuation of the flavivirus,
Powassan virus?
a.
Peromyscus leucopus
b.
Lepus americanus
c.
Marmota monax
d.
Octodon degus (answer)
ANSWERS
1.
A
2.
C
3.
A
4.
B
5.
A
6.
D
7.
(a) RNA, (b) DNA, (c) DNA, (d) RNA, (e) DNA, (f) DNA
8.
B
9.
C
10.
False
11.
A
12.
True
13.
A
14.
C
15.
D
16.
True
17.
A
18.
A
19.
A
20.
B
21.
A