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"Sleeping Beauty" named Molecule of the Year
The transposon was chosen by the International Society for Molecular and Cell Biology and Biotechnology Protocols and Research for enabling stable gene transfer in vertebrates.
Click chemistry gets a makeover for living organisms
Researchers used click chemistry to create biomolecular probes for in vivo studies of live mice for the first time by eliminating the toxic copper catalyst reaction step from the technique.
Genome-wide association studies face challenges
Researchers identify statistical and computational challenges to genetic-based disease research. advertisement
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Method extends applications for short-read sequencing
Researchers have developed a method that enhances the capabilities of current sequencing systems with tag-directed assembly of short reads.
Japanese iPS research pioneer Yamanaka speaks at the NIH
The famous stem cell researcher spoke at the NIH about his work creating iPS cells and what needs to happen before stem cell-based therapies become viable.
Novel method increases efficiency of hESC to vascular endothelial cells
A team of researchers has pinpointed the precise time at which human embryonic stem cells become committed to differentiate into endothelial cells using GFP and a
HiSeq 2000 sequencing system
Illumina’s HiSeq 2000 sequencing system generates two billion paired-end reads and 200 gigabases in a single

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New electron cryotomography technique captures neural communication
Researchers at the Max Planck Institute of Biochemistry have obtained 3-D images of vesicles involved in neurotransmission.
NIH approves two more hESC lines
The addition to the NIH Human Embryonic Stem Cell Registry raises the total number of lines eligible for federal funding to 42.
Tekmira improves its RNAi technologies
The RNAi technologies company has deciphered a cationic lipid that improves the potency of its stable nucleic acid –lipid particle delivery platform by ten-fold. advertisement run.
Genome Analyzer IIe sequencing system
Illumina’s Genome Analyzer IIe sequencing system for nextgeneration sequencing generates approximately 200 million paired-end reads and 20 gigabases of data per run at launch.
StemArray 44K Array
Ambry Genetics’ StemArray is a high resolution approach to characterizing human stem cells that has a comparable cost to standard karyotyping. advertisement
Nobel laureate receives Australia Day distinction
Elizabeth Blackburn, Australia’s first female Nobel Prize winner, has been awarded
Australia’s highest honor.
NAS to honor top life scientists
The National Academy of Sciences will honor Gerald F. Joyce and Jeannie T. Lee during its annual meeting.
Maryland Stem Cell Research Commission receives 141 applications for research funding
Though $45 million in research grants was requested, the Maryland Stem Cell Research
Commission only has $12 million available. advertisement
AFLP
In this Troubleshooting Forum column a user has a question about using AFLP.
You aren't what you eat!
GMO Compass collects objective information on genetic engineering in the agri-food
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Informa Life Sciences’ 8th Annual
Congress:
G Protein-Coupled Receptors in
Drug Discovery
Wed 17 Mar 2010 - Thu 18 Mar
2010
MARITIM proArte Hotel, Berlin,
Germany
The largest GPCRs meeting in
Europe returns in its 8th year .
The latest and most exciting

industry. advertisement
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Images should be of high scientific quality and aesthetic appeal, accompanied by a caption of up to 50 words. Covers do not have to be associated with a manuscript, although some preference will be given to those that are. Image submissions should be original source, high-resolution files.
Candidate images can be submitted together with
2008's $1000 prize went to Thomas
Deerinck of the National Center for
Microscopy and Imaging Research
(University of California, San Diego,
CA, USA) for the July 2008 cover. a manuscript at bt.edmgr.com
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BioTalk Podcast: Emerging technologies in stem cell biology
In this episode of BioTalk, Kent Vrana, Ph.D., chair of the department of Pharmacology at
Penn State University College of Medicine, and Ken Aldrich, CEO of International Stem
Cell Corporation, discuss the current state of stem cell research.
Video: Kary Mullis outmaneuvers drug resistant bacteria
Nobel Laureate Kary Mullis has developed a new technique for combating deadly drugresistant bacteria. developments in biased agonism , in silico modelling , allosterism , signalling & trafficking , structure
& mechanism , dimerisation , deorphanisation , screening methodologies and medicinal chemistry will be presented.
Download the brochure now - and find out more about our expert keynote speaker from http://www.iir-events.com/IIR-
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Immunogenicity of Biologics
2010
February 08, 2010
Mövenpick Hotel, Prague,
Czech Republic
Nano Tech 2010
February 17, 2010
Tokyo, Japan
Biophysical Society’s 54th
Annual Meeting
February 20, 2010
The Moscone Center, San
Francisco, CA
For more upcoming events in the life sciences, visit
BioTechniques' Life Science
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BioTalk Podcast: The Tet system and gene therapy
In this episode of BioTalk from BioTechniques, Gal Almogy, a post-doc at ETH Zurich explains how increasing the accuracy of the Tet system might lead to effective gene therapy. advertisement
Diffinty Genomics receives $717K from NCRR for novel PCR product
The Rochester, NY –based company plans to market their PCR cleanup filtered pipet tips this year. advertisement
Advance Online Publication: BioTechniques recently published our some peer-reviewed research articles from our February 2010 issue online before print. Here are some of the featured advanced articles.
Enhanced fluorescence imaging in chlorophyll-suppressed tobacco tissues using virusinduced gene silencing of the phytoene desaturase gene
Fluorescence imaging in plants is difficult because chlorophyll and other photosynthetic pigments can block light or autofluoresce, interfering with fluorescence imaging. Zhang et al. successfully detected fluorescence in GFP-expressing tobacco plants by employing virus-induced gene silencing to transiently silence the phytoene desaturase gene, which bleached chlorophyll-containing tissues and allowed for successful imaging.
Linear measurement of cell contraction in a capillary collagen gel system
Typically, cell contractility assays are performed in three-dimensional collagen gel systems, often making exact measurements of contraction difficult to obtain. In this
Benchmark, Ludlow and his colleagues presents a new approach to measuring cell contraction in collagen gels where the cell/collagen gel suspensions are cast in capillary tubes, which enables the linear measurement of cell contraction while at the same time uses significantly less starting material.
A proximity ligation assay using transiently transfected, epitope-tagged proteins: application for in situ detection of dimerized receptor tyrosine kinases
Guha and colleagues describe a new proximal ligation assay for the in situ visualization and quantification of receptor interactions. In their Report, the authors detail their new assay and demonstrate that the method can detect ligand-dependent dimerization of the
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epidermal growth factor receptor in a protein interaction –based manner.
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