Advanced Pharmacology (Med 752)
The Scope of this Course
Pharmacology in its broadest sense is the study of chemicals on biologic
systems substances.
This course is designed to provide the graduate student in basic medical
sciences with basic and applied knowledge in pharmacology. In this course
emphesis is placed on drug groups and prototypes rather than repetitive
detail about individual drugs. Pathophysiologic states which justify the use
of various classes of drugs will be discussed. In addition, mechanism of
action, pharmacokinetics, indications, contraindications, adverse reactions
and toxicities will be emphasized.
A journal club session will be organized in this course. In this session, the
student will be required to review selected articles in pharmacology
published in various pharmacology journals. Each student will present the
article material to the staff members and the graduate students enrolled in
this course.
A critical discussion will be conducted and directed towards the
experimental design, the statistical method, the validity of the results and
conclusions.
The students are expected to participate activity in group discussion on
various topics of pharmacology designed to be in this course.
We will also strive to encourage active learning patterns which will enable
the student in the future to cope with the continually expanding number of
therapeutic approaches to human disease.
The general topics covered in this course include:
1. Basic principles of pharmacology.
2. Drugs affecting the autonomic nervous system.
3. Cardiovascular pharmacology.
4. Drugs affecting the central nervous system.
5. Antimicrobial drugs.
6. Endocrine drugs.
7. Cancer chemotherapy.
8. Drugs used in gastrointestinal diseases.
9. Nonsteroidal anti-inflammatory drugs.
10.Drugs affecting the respiratory system.
Text and Reading Material:
The recommended text for the course is Goodman and Gilman’s.
The pharmacological Basis of Therapeutics 10th. Edition
(Mc Grow Hill, 2001). Older editions are on reserve at the library. This is a
large comprehensive text which can best be used in conjunction with:
1. Katzung’s Basic and Clinical Pharmacology, 7 th edition (Appleton and
Lange, 1998), a useful text which is particularly clear in the area of
cardiovascular pharmacology and drug metabolism.
2. Lippincott’s illustrated Reviews: pharmacology 2 nd, edition (Lippincot
Williams and Wilkins, 2000), a useful introduction to pharmacology.
Pharmacology is a rapidly changing and dynamic desipline, Several
periodicals and professional journals may be helpful to you when you
need more or current information about drugs or therapeutic principles.
Therefore you could refer to:
 The Medical letter-4 page pamphlet dealing with several drugs or
therapeutic issues.
 Pharmacology and Experimental Therapeutics
British Journal of Pharmacology
 Biochemical Pharmacology
 Drug Metabolism and Disposition
 Molecular Pharmacology
 Clinical Pharmacology and Therapeutics
 Eurepean Journal of Pharmacology
 Pharmacological Reviews