XXVII Annual Conference of Society of Toxicology, India (STOX) & International Workshop on Toxicology Towards Diplomat of American Board of Toxicology (DABT) STOX Conference : 6th & 7th October 2007 Toxicology Course : 8th to 12th October 2007 Jointly Organized By: Department of Pharmacology & Toxicology, Veterinary College, Bangalore and Advinus Therapeutics Pvt. Ltd., Bangalore. Venue: Veterinary College, Hebbal, Bangalore-560 024. Karnataka Veterinary, Animal and Fisheries Sciences University (KVAFSU). ORGANIZING COMMITTEE PATRONS PROF.R. N. SREENIVAS GOWDA Hon. Vice-Chancellor, Karnataka Veterinary, Animal and Fisheries Sciences University, Bidar – 585 401 e-mail: rns_gowda@yahoo.com DR. RASHMI BARBHAIYA CEO and Managing Director Advinus Therapeutics Private Limited 21 & 22, Phase II Peenya Industrial Area, Bangalore-560 058 e-mail: rashmi.barbhaiya@advinus.com CHAIRMAN DR.K.S.RAO Senior Director Advinus Therapeutics Pvt. LTd., Bangalore Mobile : 09880799455 e-mail: ksrao@advinus.com CO-CHAIRMAN DR.B.S.V.REDDY Dean Veterinary College KVAFSU, Bangalore e-mail: mansricha@rediffmail.com ORGANIZATION SECRETARY DR. K. JAYAKUMAR Professor & Head, Department of Veterinary Pharmacology & Toxicology 2 Veterinary College, KVAFSU, Bangalore 560024 e-maill: stox2007@rediffmail.com mail4jk@rediffmail.com Phone : 080-23415352, 080-2311483 Extn : 210 TREASURER DR. H. KRISHNAPPA, Associate Director, Advinus Therapeutics Pvt Ltd., Bangalore e-mail: krishnappa.h@advinus.com Mobile : 09880733118 CO-TREASURER DR. G. B. PRADEEP KUMAR, Advinus Therapeutics Pvt Ltd., e-mail: pradeep.kumar@advinus.com SCIENTIFIC COMMITTEE DR. A. H. SHUAIB, Associate Professor Department of Pharmacology & Toxicology, KVAFSU, Bangalore 560024 e-mail: ahshuaib@rediffmail.com Tel. : 080-23415352 CO-CHAIRPERSONS DR. T.P. SURESH Expert consultant, Toxicology & GLP DR. JAGADISH KUMAR Retd. Professor, KVAFSU, Bangalore DR. S. YATHIRAJ, Professor, KVAFSU, Bangalore. MEMBERS DR. PRAKASH NADOOR, Associate Professor, KVAFSU, Bidar. pnadoor@yahoo.com DR.N.B.SRIDHAR, Assistant Professor, KVAFSU, Bangalore-560024 e-mail: sridhar_vet@rediffmail.com DR. VENUGOPALA RAO, Advinus Therapeutics Pvt Ltd., e-mail: venugopala.rao@advinus.com DR. SYED MANZOOR SULAIMAN, Advinus Therapeutics Pvt Ltd., e-mail : syed.sulaiman@advinus.com DR. P. ANIL KUMAR, Advinus Therapeutics Pvt Ltd., e-mail: anilkumar.p@advinus.com Distinguished Colleagues: It is our immense pleasure to announce that the 27 th Annual meeting of the Society of Toxicology, India (STOX) for 2007 will be jointly organized by the Department of Pharmacology and Toxicology, Veterinary College, Bangalore and Advinus Therapeutics Private Limited, Bangalore. The theme of the meeting is “Regulatory Toxicology Current Perspectives and Future Challenges”. The meeting will be held in two parts. The 27th Annual Conference of Society of Toxicology, India (STOX) will be organized on 6th and 7th October 2007. The International Workshop on Toxicology towards the Diplomate of the American Board of Toxicology (DABT) will be held from 8 th to 12th October 2007. Both the meetings will be held under the auspices of the Veterinary College, KVAFSU, Bangalore560 024, Karnataka State. The objective of this year’s conference is to provide a forum for deliberation on regulations concerning drugs, new chemical entities and biotech products. In addition to the platform and poster presentation in the two day STOX conference, there will be a workshop on the afternoon of 7th October 2007 wherein 10 toxicology professors from USA will provide their 3 toxicological expertise to attendees of STOX conference. The US speakers will emphasize the scientific and strategic approach to management of safety/risk assessment, and also provide an insight into new emerging challenges to the pharmaceutical and biotech research. Immediately following the formal STOX meeting, there will be an intensive Toxicology course from 8th to 12th October 2007 at the same venue. The course is designed to cover the entire field of toxicology for those who want to advance their career in industrial toxicology and also to provide guidance for those who plan to take the DABT examination. This course will be conducted by 12 eminent US professors who offer the Mid-America Toxicology course in US as a preparatory course towards the American Board of Toxicology (ABT) examination. The STOX organizers are also working with the ABT Board in US to conduct the ABT examination in INDIA in 2008. Who Should Attend? Toxicologists, Pharmacologists and Pathologists who are working in Industry, Academia and Government Institutions. Health and safety professionals from Industry and Academia and Government. Laboratory animal researchers, Veterinary, Forensic medicine and Pharmaceutical scientists. Attendees for this years’ conference can choose any combination of the following: Any participant can attend only the STOX meeting on 6th and 7th October 2007 Any participant can attend only the Toxicology course from 8th to 12th October 2007 Any participant can attend both the STOX meeting (6th and 7th October) and the Toxicology course (8th to 12th October). REGISTRATION XXVII Annual Conference of Society of Toxicology, India (STOX) And International Workshop on Toxicology Towards Diplomate of American Board of Toxicology (DABT) Registration Form (Please Type Or Print) Name:………………………………………………………………………………………………………………... Address:……………………………………………………………………………………………………………... …………………………………………(City)……………………………….(Pin)………………………………… (State)……………………………............... Gender: Male Female Telephone: [Off.]…..…………………….[Res.] …..……………………. [Cell] …..……………………………. Fax: …..…………………….E-mail:…..…………………….…..………………………………………………… 4 Food Preference: Vegetarian Non-Vegetarian Registration: STOX Conference Toxicology Course D.D. / Cheque: Rs………………. Rs………………. Total Rs………………. Enclosed please find a Crossed Cheque / D.D. for Rs……….…………(Rs………………………….. …………………………………………………………………………………...Only) Bearing No………………. Dated……..……………..Drawn on…………..…………………………………..………………………..(Bank) payable at Bangalore in favor of “TREASURER, STOX-2007” and send to: DR.K.JAYAKUMAR, Organizing Secretary, Department of Pharmacology & Toxicology Veterinary College, Hebbal, Bangalore-560024, Karnataka State, INDIA. Registration fee for STOX Conference: Members of STOX / ASAW* Rs.1000/Non members : Rs.1200/Students: Rs.0800/Associate delegate: Rs.0500/* Registration fee for Toxicology Course University Staff: Rs.15,000/Govt. Institutions: Rs.20,000/Corporate sectors: Rs.50,000/- ASAW: Academy of Sciences for Animal Welfare Any participant can attend only the STOX meeting on 6th and 7th October 2007 Any participant can attend only the Toxicology course from 8th to 12th October 2007 Any participant can attend both the STOX meeting (6th and 7th October) and the Toxicology course (8th to 12th October) Note: Eligibility for attending DABT course: Any post graduate in the related field with 3 years experience in the area of Toxicology. Registration for Toxicology Course is limited to 100 Nos. Preference will be given on first come first serve basis. Due to preparation of large volume of handouts and text books, for the Toxicology course only pre-registration will be accepted. Last date for pre-registration for the Toxicology course is 15th August, 2007. ACCOMMODATION Guest house facilities are limited and would be provided on advance intimation on first come first serve basis. The rest of the delegates will be assisted in getting accommodation in hotels on request with prior payment for the same. Type of accommodation required: Guest house Rs.250/day Hostel Rs.60/day (Dormitory): Hotel Single A/c rooms ………………………………………………………... Double A/c rooms ………………………………………………………... From:………………………………..to……………………………….. Total No. of Days:………………. Each registrant will be informed of their accommodation details following receipt of the registration application. Those wishing to stay in the hotel, please provide your choice of the hotel from the below list: - 5 TARIFF OVER RS.6000/ ITC Windsor Sheraton Sankey Road, Bangalore Le Meridien Sankey Road, Bangalore The Grand Ashok Kumara Krupa High Grounds, Bangalore Taj Westend Race Course Road, Bangalore TARIFF RS 4000 TO 6000/ The Atria No.1, Palace Road, Bangalore. The Capitol Raj Bhavan Road, Bangalore. TARIFF RS 1500 TO 3000/ Ashraya International Hotel 149, Infantry Road, Bangalore Chancery Hotel Lavelle Road, Bangalore Harsha Hotel & Convention Center 11, Park Road, Bangalore. Hotel Empire International 36, Church Street, Bangalore - 560 001 Hotel Maurya 22/4, Race Course Road, Gandhi Nagar, Bangalore. The Basil 8th Cross, Sampige Road, Malleshwaram, Bangalore. Submission of Abstracts: The abstract of about 250 words including title, authors and address should be typed in MS Word in Times New Roman (size 12) in single spacing. The abstract should briefly include the purpose of study, methods, results and conclusions. The name of the presenting author should be underlined. Abstract with email address should be submitted preferably on CD or 1.44" floppy disk (virus free) or through E-mail. Two hard copies of abstract must accompany the registration form. The submission through CD/ floppy disk is a must if not sent by E-mail. Only registered delegates can submit abstracts for oral/poster presentation. The materials for fixing the posters (thumb tacks and display board) will be provided by the Organizers. The E-mail version of abstracts, the hard copies of papers or abstracts/floppies along with registration form & fee should reach the Organizing Secretary by 15th August 2007 The Abstracts may be submitted under the following categories: - 6 1. Acute, Subacute, Subchronic and Chronic toxicity 2. Reproductive Toxicity and Teratology 3. Mutagenicity and Carcinogenicity 4. Safety Pharmacology 5. Immunotoxicology 6. Environmental / Ecotoxicology 7. Plant and Mycotoxicology 8. Occupational toxicology 9. Toxicology of food adulterants AWARDS Research scholars who are below 35 years of age (as on 1.7.2007) are eligible for the following awards. The applicant must be a member of STOX and submit the proof of age. Seth Roop Lal Aggarwal Memorial Award: Oral presentation. STOX Best Poster Presentation Award Prof P.K.Gupta Young Scientists Travel Award (request for travel grant for oral presentation along with full paper should be submitted to the executive secretary of STOX. STOX/ASAW "Surajben Jetha Lal Thakur Prakruti Gold Medals" for Animal Welfare. Applications should be mailed to the President ASAW by 30th June, 2007 (for details please see website: www.stoxindia.org.in). Bangalore is the capital of Karnataka, located on the southern Deccan Plateau. Bangalore has had many nick-names over the years from the 'pensioner's paradise' to the 'IT capital of India', As a thriving business center, focusing on information technology (IT), Bangalore is considered the IT capital of India, often called the "Silicon Valley of India", Bangalore has come a long way. Today, the city is the nerve-center for many Indian as well as multinational Biotechnology, Information Technology, Pharmaceutical Research and Development Companies. The following tours / sight seeing trips are organized through Karnataka State Tourism Development Corporation (KSTDC) http://kstdc.nic.in Bangalore Sight-Seeing Tour Belur, Halebid and Shravanabelagola Mysore, Srirangapattana, Ooty & Nanjanagud Nandi Hills, Muddenahalli Mysore Sight - Seeing Tour Tirupati and Mangapura Bannerughatta and Muthyalamaduvu Goa, Gokarna 7 Hogenakal Falls, Krishnagiri Dam Nagarahole, Mercara, Nisargadhama Shivanasamudra, Somnathpur, Ranganathittu Jog Falls, Dharmashala MID-AMERICA TOXICOLOGY COURSE Course Director Curtis D. Klaassen, Ph.D., DABT Location Veterinary College, KVAFSU Hebbal, Bangalore, India Dates 8 – 12 October 2007 TOXICOLOGY COURSE SCHEDULE 8:00-9:30am 9:30-9:45am 9:45-11:30am Mon. 11:30-12:30pm Oct. 8 12:30-2:00pm 2:00-3:55pm 3:55-4:10pm 4:10-5:30pm General Principles of Toxicology Coffee Break Mechanisms of Toxicity Chemical Disposition (Absorption, Metabolism, Excretion, Kinetics, and Factors Affecting These) Lunch Break Chemical Disposition (continued) Break Developmental Toxicology 8:00-9:50am 9:50-10:05am 10:05-12:00 noon Tue. 12:00-2:00pm Oct. 9 2:00-3:55pm 3:55-4:10pm 4:10-5:00pm 5:00-6:00pm Chemical Carcinogenicity Coffee Break Genetic Toxicology-Mutagenesis Lunch Break Toxic Responses of the Nervous System and Behavioral Toxicology Break Toxic Responses of Eyes Toxic Responses of Skin 8:00-9:50am 9:50-10:05am 10:05-12:00 noon Wed. 12:00-2:00pm Oct. 10 2:00-3:55pm 3:55-4:10pm 4:10-5:30pm Toxic Responses of Blood Coffee Break Immunotoxicology Lunch Break Toxic Responses of Liver and Kidney Break Clinical Toxicology 8:00-10:20am 10:20-10:35am 10:35-12:30pm Thu. 12:30-2:00pm Oct. 11 2:00-3:50pm 3:50-4:10pm 4:10-6:00pm Inhalation & Toxic Responses of Lung Coffee Break Toxic Effects of Pesticides Lunch Break Toxic Effects of Metals Break Toxic Effects of Solvents Klaassen Klaassen Distribution, Klaassen Klaassen K.S.Rao Cohen Brusick Fox Fox Belsito Bloom Pazdernik Klaassen Cantilena Alarie K.S.Rao Clarkson Klaassen 8 Fri. 8:00-10:30am Oct. 12 Toxins Occurring in Nature: Animals, Plants and Fungi Oehme SPEAKER BIOS Curtis D. Klaassen Dr. Klaassen is University Distinguished Professor and Chairman of the Department of Pharmacology and Therapeutics at the University of Kansas Medical Center in Kansas City, KS. Dr. Klaassen is founder (1980) and Course Director of the Mid-America Toxicology Course, an annual postgraduate course in toxicology. He is the editor of Cassrett and Doull’s Toxicology: The Basic Science of Poisons since 1980. Samuel Cohen Dr. Cohen is professor and Chair of the Department of Pathology and Microbiology at the University of Nebraska Medical Center, Omaha, NE. He has been active in several scientific organizations, including the Society of Toxicology and Society of Toxicologic Pathologists, and has been on the scientific advisory boards for the NIH, and EPA. His research interests are in the mechanisms of chemical carcinogenesis and risk assessment. Donald A. Fox Dr. Fox is a Professor of Vision Sciences and Biochemical and Biophysical Sciences at the University of Houston. He has served on the NIEHS Superfund, NIH Vision Sciences Study Section and others. He is on Editorial Boards of numerous journals. John C. Bloom Dr. Bloom is a Clinical Research Fellow and Director of Experimental Medicine at Lilly. He is the past president of American Society of Veterinary Clinical Pathology. Yves Alarie Dr. Alarie is a Professor in the Department of Environmental and Occupational Health, University of Pittsburgh. His research interests are focused on respiratory toxicology and published extensively on the use of animal models to estimate safe levels of exposure for airborne chemicals and their mixtures. Thomas Clarkson Dr. Clarkson is a Professor and Chairman of the Department of Environmental Medicine. His research interests are in toxicology of heavy metals. Dr. Clarkson has authored over 200 research articles and has co-authored 4 books. Frederick W. Oehme 9 Dr. Oehme is Professor of Toxicology and Pathobiology and Director of Comparative Toxicology Laboratories in the College of Veterinary Medicine at Kansas Stare University. He is past president of the Society of Toxicology, the American Academy of Clinical Toxicology and the World Federation of Clinical Toxicology and Poison Control Centers. Thomas L. Pazdernik Dr. Pazdernik is Professor of Pharmacology, Toxicology and Therapeutics at the University of Kansas Medical Center. His research interest is focused on biochemical basis of brain injury associated with chemicals, free radical mechanisms in brain injury. David J. Brusick Dr. Brusick is Vice-President for Global Toxicology for Covance. His research interests include mutagenic and carcinogenic mechanisms with chemicals and the application of biotechnology to safety testing method development. K.S. Rao Dr. Rao is Senior Director of Safety Assessment at Advinus Therapeutics, Bangalore. Prior to joining Advinus, Dr. Rao served as Director of Toxicology at Micagenix in Indianapolis and Executive Director of Toxicology at Quintiles and Aptuit in Kansas City, MO. He has over 35 years of Pharmaceutical (G.D. Searle), Pesticide and chemical industry (Dow Chemical Company) experience in the conduct of studies for safety/risk assessment of products Donald V. Belsito Dr. Belsito is a Professor of Medicine (Dermatology) and Director of the Division of Dermatology at the University of Kansas Medical Center. He is a founding member and current Vice President of the American Contact Dermatitis Society. His research interests include delayed-type hypersensitivity of the skin and occupational dermatoses.