Medical University of Warsaw 2nd Faculty of Medicine - English Division 61 Żwirki i Wigury Street 02-091 Warsaw Phone: + 48 (22) 5720 502 Fax:+48 (22) 5720 562 e-mail: english@wum.edu.pl http: www.wum.edu.pl 2nd YEAR CURRICULUM 4-year program Warsaw, 2010/2011 1 PHARMACOLOGY Department of Clinical and Experimental Pharmacology Address: 26/28 Krakowskie Przedmiescie St., 00-957 Warsaw Phone/fax: 022 826 21 16; mirdag@poczta.onet.pl Head: Prof. Andrzej Członkowski, MD, PhD Curricular affairs: Dagmara Mirowska, MD, phone : 4822 501 322171 Adam Kobayashi, MD, phone: 4822 602 266 498 Number of teaching hours: seminars – 80 hours lectures – 40 hours Assessment of student performance: On completion of the course students are expected to take test with 100 multiple choice questions. The aim of the course: During two semesters of pharmacology students are expected to gain the basic knowledge of pharmacokinetics: drugs absorption, distribution, elimination and biotransformation, pharmacodynamics: drugs action and interaction, relationship between drug concentration and effect on human body by altering biological functions in health and disease, therapeutic usfulness, indications and contraindications, dosage, route of administration, side effects, toxicity and principles of prescribing. The next aim of the program is to update students with main drug groups used in common diseases. Topics of lectures: 1. Introduction to pharmacology. Basic pronciples 2. Pharmacokinetics: drug absorption, distribution and elimination 3. Drug biotransformation 4. Pharmacodynamics: drug action, the relationship between drug concentration and effect 5. Special aspects of pharmacotherapy during pregnancy and lactation. Drugs used during pregnancy and lactation 6. Principles of chemotherapeutic drug action 7. Antifungal, antiviral drugs 8. Malaria – treatment and prophylaxis 9. Drug used in chemotherapy of tuberculosis and leprosy 10. Cancer chemiotherapy 11. Pharmacology of vitamins 12. The hypothalamic and pituitary hormones. Thyroid and antithyroid drugs 13. The gonadal hormones and inhibitors 14. Antiallergic drugs 15. Immunopharmacology 16. Agents acting at the neuromuscular junction and autonomic ganglia 17. Local anaesthesia 18. Mechanism of drug interactions 2 19. Drug treatment of angina pectoris 20. Drugs used in hiperlipidemias 21. Drug therapy of hypertension 22. Therapeutic management of shock 23. Occupational and enviromental toxicology 24. Harmful effects of drugs. Principles of toxicology 25. Introduction to psychopharmacology 26. Pharmacology of Parkinson’s disease and movement disorders 27. Pharmacology of alcohol consumption 28. Drug of abuse (part one) 29. Drug of abuse (part two) 30. Therapy of cognitive disorders 31. Management of patient with vascular diseases of the central nervous system 32. Multiple sclerosis treatment 33. Special aspects of geriatric pharmacology 34. Drugs affecting the haematopoetic system Topics of seminars: 1. Drug used in gastrointestinal diseases. Control of gastric acidity and treatment of peptic ulcers 2. Drugs used in gastrointestinal diseases. Emetic and antiemetic drugs. Drugs increasing gastro-intestinal motility. Antidiarrhoeal drugs 3. Antihelmintic drugs 4. Antiprotozoal drugs 5. Assesment test on gastrointestinal drugs 6. Prescription writing 7. Chemotherapeutic agents. Sulfonamides. Quinolones. Urinary antiseptics 8. Chemotherapeutic agents. Penicilins. Cephalosporins and other beta-lactam antibiotics. Macrolide antibiotics 9. Chemotherapeutic agents. Chloramphenicol. Tetracyclines. Aminoglycosides 10. Assessment test on chemiotherapy 11. Adrenocorticosteroids and adrenocortical antagonists 12. Vitamin D, calcium homeostasis, parathyroid hormone and calcitonin 13. Pancreatic hormones and antidiabetic drugs 14. Assesment test on hormonal agents 15. Dermatologic pharmacology 16. Drugs used to influence smooth muscle organs 17. Cholinergic agonists. Cholinoreceptor-blocking drugs 18. Catecholamines and sympathomimetics drugs 19. Adrenergic receptor antagonists 20. Diuretic agents 21. Anticoagulant and antiplatelet drugs 22. Agents used in cardiac arythmias 23. Antihypertensive drugs 24. Agents used in congestive heart failure 25. Assessment test on drugs used in cardiovascular diseases 26. Bronchodilatators and other agents used in asthma and COPD 27. Management of poisoned patient 28. Non-steroid anti-inflammatory drugs 3 29. Opioid analgesics and antagonists 30. General anaesthetics. Inhalational anaesthetics. Injectable anaesthetics 31. Antiepileptic drugs 32. Drugs used in mood disorders 33. Antipsychotic drugs 34. Anxiolytics. Psychostimulants 35. Prescribing and prescription writing 36. Assesment test on CNS and analgesic drugs Practical classes: No practical training Basic textbooks: 1. Katzung B.G.: Basic and Clinical Pharmacology, Lange Medical Books/McGraw – Hill, New York, 2001 Complementary textbooks: 1. Hardman J.G et all.: Goodman and Gilman’s pharmacological basis of therapeutics, Pergamon Press, New York, 1996 2. Rang H.P. et all.: Pharmacology, Elsevier, London, 2003 3. Neal M.J.: Medical Pharmacology at a Glance, Blackwell Science, Oxford, 2002 LECTURES – on Mondays 2008-10-27 nr 1 Responsible person Marek Postuła, MD 6 Topic Introduction to pharmacology. Basic principles Pharmacokinetics: drug absorption, distribution, elimination. Drug biotransformation Antifungal, antiviral and antihelmintic drugs Drugs used in chemiotherapy of tuberculosis and leprosy. Antiprotozoal drugs The gonadal hormones and inhibitors. The hypothalamic and pituitary hormones Malaria – treatment and prophylaxis 7 Thyroid and antithyroid drugs Aleksandra Wasłowska, MD 8 Pharmacology of vitamins Aleksandra Wasłowska, MD 9 Aleksandra Wasłowska, MD 11 Agents acting at the neuromuscular junction and autonomic ganglia Harmful effects of drugs. Principles of toxicology Occupational and enviromental toxicology 12 Local anaesthesia Prof. Ewa WidyTyszkiewicz Prof. Ewa WidyTyszkiewicz Aleksandra Wasłowska, MD 13 Principles of pain treatment Jan Bębenek, MD 2 3 4 5 10 Marek Postuła, MD Marek Postuła, MD Marek Postuła, MD Jan Bembenek, MD Jan Bębenek, MD Date 2010-09-27 14.00-14.45 2010-10-04 14.00-15.30 1h 2h 2010-10-11 14.00-15.30 2010-10-18 14.00-15.30 2h 2010-10-25 14.00-15.30 2010-11-08 14.00-14.45 2010-11-15 14.00-14.45 2010-11-22 14.00-14.45 2010-11-29 14.00-15.30 2010-12-06 14.00-14.45 2010-12-13 14.00-14.45 2011-01-03 14.00-14.45 2011-01-10 14.00-14.45 2h 2h 1h 1h 1h 2h 1h 1h 1h 1h 4 14 Jan Bębenek, MD Inhalational and injectable anaesthestics General anaesthesia. 2011-01-17 14.00-15.30 Total hours 2h 20 SEMINARS – on Thuesdays from 2010-09-28 nr 1 Topic Resposible person Principles of chemiotherapeutic drug Marek Postuła, MD action. Mechanisms of antibiotic resistancy 2 Chemiotherapeutic agents (part I) Marek Postuła, MD 3 Chemiotherapeutic agents (part II) Marek Postuła, MD 4 Pancreatic hormones and antidiabetic drugs Marek Postuła, MD 5 Opioid analgetics Marek Postuła, MD 6 Vitamin D. Calcium homeostasis. Parathyroid hormone and calcitonin Jan Bembenek, MD 7 Adrenocorticosteroids and adrenocortical antagonists Jan Bębenek, MD 8 Cholinergic drugs. Cholinergic antagonists. Catecholamines and sympathomimetics. Adrenergic receptors antagonists Assessment test on hormones and chemiotherapy Jan Bembenek, MD 10 Drugs used to influence smooth muscle organs Aleksandra Wasłowska, MD 11 Non-steroid antiinflammatory drugs Aleksandra Wasłowska, MD 12 Management of poisoned patients Prof. Ewa WidyTyszkiewicz 13 Drugs used in gastrointestinal diseases. Control of gastric acidity and treatment of peptic ulcer Drugs used in gastrointestinal diseases. Emetic and antiemetic drugs. Drugs increasing gastrointestinal motility. Antidiarrhoeal drugs Jan Bębenek, MD 9 14 Jan Bembenek, MD Jan Bębenek, MD Date 2010-09-28 16.00-18.30 gr. 1 18.30-21.00 gr. 2 2010-10-05 16.00-18.30 18.30-21.00 2010-10-12 16.00-18.30 18.30-21.00 2010-10-19 16.00-18.30 18.30-21.00 2010-10-26 16.00-17.45 17.45.-19.30 2009-11-02 16.00-18.30 18.30-21.00 2010-11-09 16.00-18.30 18.30-21.00 2010-11-16 16.00-18.30 18.30-21.00 3h 3h 3h 3h 2h 3h 3h 3h 2010-11-23 16.00-18.30 18.30-21.00 2010-11-30 16.00-18.30 18.30-21.00 2010-12-07 16.00-18.30 18.30-21.00 2010-12-14 16.00-17.45 17.45.-19.30 2011-01-04 16.00-18.30 18.30-21.00 2011-01-11 16.00-18.30 18.30-21.00 3h Total hours 40 3h 3h 2h 3h 3h 5 PATHOPHYSIOLOGY Department of General & Experimental Pathology Address: 26/28 Krakowskie Przedmieście Street, 00-927 Warsaw Phone: 022 826 81 41 fax: 022 826 45 85 www.pathophysiology.amwaw.edu.pl Head Prof. Sławomir Maśliński, MD, PhD Curricular affairs: Grzegorz Szewczyk, MD Number of teaching hours: seminars: 90 hours divided in 2 two-weeks sections Assessment of student performance: Students are expected to take a credit after each section and on completion of the course students are expected to take final test examination. The aim of the course Pathophysiology emphasizes the relationship between abnormal function and clinical manifestations of disease. It explains pathogenesis of diseases and gives the ground for possible treatment. Topics of seminars 1. Pathophysiology of the nervous system 2. Disorders of endocrine system 3. Diabetes 4. Immunopathology 5. Pathophysiology of reproductive system 6. Circulatory system – heart insufficiency, myocardial infarction, arterial hypertension 7. Oedemas, shock 8. Pathophysiology of kidneys 9. Pathophysiology of liver 10. Pathophysiology of respiratory system 11. Electrolytes 12. Blood – anemias and neoplasmatic diseases 13. Blood – hemostasis disorders 14. Disordes of acid – base balance 15. Pathophysiology of gastrointestinal system 16. Metabolic diseases 17. Pathophysiology of rheumatic diseases. Basic textbook SJ McPhee, VR Lingappa, WF Ganong. - Pathophysiology of disease. Lange, 6th edition, 2005 Complementary textbook CE Kaufman, PA McKee – Essentials of pathophysiology. Lippincott Williams & Wilkins, 1997. 6 PATHOMORPHOLOGY Chair and Department of Pathology Address: 7, Pawińskiego Street., 02-106 Warsaw, phone/fax 0 22 822-70-53 Head: Prof. Aleksander Wasiutyński, MD, PhD. Curricular affairs: Magdalena Bogdańska, MD, phone 0 22 599-16-72 Number of teaching hours: - Lectures 60 hrs - Seminars 50 hrs - practical training 90 hrs Assessment of student performance: Colloquia according to the schedule within the academic year. On completion of the course students are expected to take final assessment test. The aim of the course: The course program offers to the students the basic information of the essential terms and problems of pathomorphology: definition of lesion, its morphology, pathogenesis, pathological and clinical consequences, correlations between the lesion and systems of body. Topics of lectures: General pathomorphology 1. Disorders of circulation. 2.Regressive lesions (cell injury and adaptations). 3. Neoplasia. 4. Inflammation Organ pathomorphology 1. Heart and vessel. 2 Respiratory system. 3. Gastrointestinal tract, liver and pancreas. 4. Urinary tract. 5. Male and female genital tract Topics of seminars: 1. Pathology of haematopoetic system. 2. Neuropathology. 3. Musculo-skeletal system. 4. The demonstration of current autopsies Topics of practical classes: The review of about 200 selected histopathological slides, considered as the illustration and extension of the material presented during the lectures. Basic textbook: 1. Cotran RS, Kumar V, Collins T: Robbins Pathologic Basis of Disease. W.B.Saunders Company, the latest available edition Complementary textbooks: 1. Kruś S: Launching pad into the life-long study of Pathologic Anatomy. Script edited by the Medical University of Warsaw, 2000 2. Kruś S: Guide through pathomorphology for students who have enough time think it over. Script edited by the Medical University of Warsaw 3. Kruś S: Guide and comments to histopathological classes. Script edited by the Medical University of Warsaw, 2004 7 MEDICAL MICROBIOLOGY Chair and Department of Medical Microbiology Address: 5 Chalubinskiego Street, 02-004 Warsaw, Poland Tel./fax: 022 628 27 39 http://mikrobiologia.wum.edu.pl/node/95 Head: Prof. Grażyna Młynarczyk, MD, PhD Curricular affairs: Marta Wroblewska, MD, PhD, DTM&H, M. Med (Microbiology) Phone: 022 622 00 28 Number of teaching hours: – lectures: 15 hours – seminars: 5 hours – laboratory classes: 70 hours Assessment of student performance: On completion of the course students are expected to take a final examination (written) at the end of the IVth semester (MCQ test). Aim of the course: The students learn basic properties of viruses, bacteria and fungi of medical importance. They gain the knowledge of the virulence factors of the microorganisms, pathogenesis and epidemiology of infections caused by these pathogens, as well as host defence mechanisms. The subject of medical microbiology comprises also the clinical symptoms of viral, bacterial and fungal diseases. One of the main objectives of the course is to teach the students laboratory diagnosis of these infectious diseases. The students must also know the principles of the available antimicrobial treatment and prophylactic measures to prevent the infections. Topics of lectures: 1. Pathogenesis of viral infections in humans. Disease patterns of viral infections. Epidemiology of viral infections in humans. 2. Respiratory RNA viruses. 3. Rabies. Viral haemorrhagic fevers. 4. Viral hepatitis. HIV infection / AIDS. 5. Antiviral chemotherapy. Prophylaxis of viral infections. 6. Structure and physiology of bacteria. Bacterial genetics. 7. Pathogenesis of infections caused by Gram (+) cocci and Gram (-) bacilli. 8. Pathogenesis and epidemiology of bacterial infections. 9. Antibacterial agents and chemotherapy. 10. Spore-forming and non-sporing anaerobes. 11. Tuberculosis and mycobacterioses. 12. Zoonoses. 13. Hospital-acquired infections. 14. Prophylaxis and vaccination against bacterial infections. 15. Prion diseases. Topics of seminars: 1. Relevance of microbiology laboratory diagnostic tests to the general practitioners. Molecular techniques in laboratory diagnosis of infections. 8 2. Physiological microbial flora. Infections in the immunocompromised host. 3. Etiology and prophylaxis of infectious diseases in travelers. 4. New and re-emerging infectious diseases. 5. Bioterrorism. Topics of laboratory classes: 1. General properties of viruses. Methods of culture. Laboratory diagnosis of viral infections. 2. DNA viruses. 3. RNA viruses. 4. Viral hepatitis. HIV infection / AIDS. 5. Colloquium. Assessment / credit for virology practical classes. Principles of bacteriological examination. Methods of isolation and identification of bacteria. 6. Sterilisation and disinfection. Gram-positive cocci and Gram-negative cocci. 7. Gram-negative aerobic bacilli. Microaerophilic and capnophilic bacteria. Spirochaetes. 8. Chemotherapy of bacterial infections. Anaerobic bacteria. 9. Fungi, rickettsiae, mycoplasmas, chlamydiae. Bacteria: Mycobacterium, Corynebacterium, Bordetella. 10. Colloquium. Respiratory tract infections. Infections of the blood. Hospital-acquired infections. 11. Gastro-intestinal tract infections and intoxications. Infections of the central nervous system. 12. Genito-urinary tract infections. Sexually transmitted diseases. Congenital and perinatal infections. 13. Infections of the skin and soft tissues. Infections of the eye. Dental infections. 14. Colloquium. Credit for bacteriology practical classes. 15. Re-take colloquium and credit for bacteriology practical classes. Basic textbooks: 1. Medical Microbiology. P. R. Murray, K. S. Rosenthal and M. A. Pfaller. Mosby Co. Sixth ed., 2009. 2. Jawetz, Melnick & Adelberg’s Medical Microbiology. G. F. Brooks, K. C. Carroll, J. S. Butel, S. A. Morse. Lange, 24th ed., 2007. 3. Review of Medical Microbiology and Immunology. W. Levinson. Lange. Ninth ed., 2006. Complementary textbooks: 1. Lippincott’s Illustrated Reviews: Microbiology. W. A. Strohl, H. Rouse, P. C. Champe, R. A. Harvey. Lippincott Williams &Wilkins. Second ed., 2007. 2. Medical Microbiology. F. H. Kayser, K. A. Bienz, J. Eckert, R. M. Zinkernagel. Thieme Medical Publishers, 2005. 3. Mims’ Medical Microbiology. R. Goering, H. Dockrell, M. Zuckerman, D. Wakelin, I. Roitt, C. Mims, P. Chiodini. Mosby Co. Fourth ed. 2007. 9 NEUROBIOLOGY Coordinator of teaching and curricular affairs: Ewa Koźniewska, MSc, PhD. Chair and Department of Experimental and Clinical Physiology Address: 3C Pawinskiego Street Phone: 022 608 64 89, through the Dean`s Office or e-mail: ewak@cmdik.pan.pl Number of teaching hours: 46 hours of lectures 4 hours of clinical classes (patients demonstration) Aim of the course: Neurobiology aims to prepare students for the neurology course basing on the knowledge of neurophysiology acquainted during the 1st semester of the study. The teaching is carried out in the 4th semester by the Departments of Physiology, Anatomy, Neuropharmacology, Nuclear Medicine and Neurology. On completion of the course students are expected to take final MCQ examination . Topics of lectures: 1. The somatosensory cortical areas. Physiological basis of cognition: reception, sensation and perception. Sensory deficits. Organization of visual perception. Organization of auditory perception. Disturbances of perception: agnosias – 5 hours 2. Physiology of higher psychic functions. Plasticity of the brain. Physiology of drives and emotions. Conditioned reflexes – 6 hours 3. Supraspinal control of motor activity. Cortical control of motor activity. Motor disturbances caused by cortical lesions: cerebral palsy, apraxias. Physiology and pathology of basal ganglia and cerebellar control of motor activity – 4 hours 4. Main neurotransmitter pathways of the brain. Reward system. Mood regulation. Action of drugs in the central nervous system. The classification of psychotropic drugs. Mechanism of drug addiction – 6 hours 5. Cerebral blood flow and metabolism. Mechanisms of neurovascular coupling. Homeostatic mechanisms in the central nervous system – 5 hours 6. Genetic, autoimmune and transcriptional channelopathies – 1 hour 7. Anatomy and neurological examination – 2 hours 8. Anatomy of the traumatic brain injury – 2 hours 9. Brain ischemia and hemorrhage – 2 hours 10. Tumors of the CNS- basic concepts – 2 hours 11. Physical basis of brain imaging modalities – 2 hours 12. Application of imaging techniques for clinical diagnosis – 4 hours 13. Stem cells, genetic engineering, trophic factors – future treatment in neurology - 2 hours 14. Mechanisms of neurodegeneration -1 hour 15. Spasticity as a neurological problem - 2 hours Topics of clinical practical : 1. Diagnostics tests in neurology - 2 hours 2. Main neurological signs and symptoms - 2 hours Detailed program is available at www.wum.edu.pl/physiology Recommended textbooks: Kandel E, Schwartz JH, Jessell TM. Principles of Neural Science. 4th edition, 2000, Elsevier, New York. 10 DIAGNOSTIC IMAGING Diagnostic Imaging Department Address : Wojewódzki Szpital Bródnowski, 8 Kondratowicza Street, 03-242 Warsaw Phone: 022 674 00 38 from 8.00am to 1.00pm; zdo@usgptu.waw.pl Head of the Department: Professor Wiesław Jakubowski Responsible for teaching: Professor Wiesław Jakubowski, MD, PhD, Bartosz Migda, MD Curricular affairs : Bartosz Migda, MD Number of teaching hours: Lectures 10 hours Practical training 65 hours ( including 18 hours of Pediatric Radiology) Seminars 15 hours Credit: Oral examination. Students are obliged to be present at all lectures, seminars and practical training, this includes Pediatric Radiology. The credit in Pediatric Radiology enables students to take exam in Diagnostic Imaging. Course description: Students have their practical training in Ultrasound Department, Magnetic Resonance Department and Nuclear Medicine Department. Lectures and seminars are held in lecture hall located in Magnetic Resonance Department. The topics of lectures and seminars include : physics and instrumentation, clinical applications, diagnostic algorithms, therapeutic procedures and many more. Students are divided into small groups for their practical training. They have the opportunity of performing ultrasound examinations themselves and take part in Magnetic Resonance Examinations, CT and Nuclear Medicine Examinations. Textbooks: MRI of Brain and Spine, Scott W. Atlas, 2002, Lippincott Williams&Wilkins MRI of the Hand and Wrist, Thomas H. Berquist,2003, Lippincott Williams&Wilkins Differential Diagnosis in Magnetic Resonance Imaaging, F.A. Burgener, S.P. Mayers,R. K. Tan, 2002, Thieme Emergency Pediatric Radiology, Carty. H.,2002 , Springer Verlag Neuropathology and Neuroradiology J. S. Citow, R. L. Macdonald, R. M. Kraig, R. L. Wollmann, 2002, Thierme Fundamentals Gastrointestinal Radiology, Michael Davis, Jeffrey D. Houston, 2001, Saunders Koehler/Zimmer’s Borderlands of Normal and Early Pathological Findings in Skeletal Radiography, Jurgen Freyschmidt, Joachim Brossmann, Andreas Stenberg, Juergen Wiens, 2003, Thieme CT of the Head and Spine, Norbert Hosten, Thomas Liebig, 2002 11 PEDIATRIC RADIOLOGY Department of Pediatric Radiology Address: 24 Marszałkowska Street; 00-576 Warsaw Phone/Fax: 022 628 52 19; e-mail: amarcinski@litewska.edu.pl Head: Prof. Andrzej Marciński, MD, PhD Curricular affairs: Anna Jakubowska, MD Number of teaching hours: Classes, seminars – 18 Duration of the course: 8.15 a.m. – 1.00 p.m. Assessment of student performance: On completion of the course students are expected to take final assessment test (oral ) The course program offers to students the basic information connected with: - practical algorithms in diagnostic imaging in pediatrics, - assessment of the effectiveness of several diagnostic imaging modalities applied to the most common clinical conditions in pediatrics Topics of seminars: 1. Diagnostic imaging in respiratory tract diseases in children – Agnieszka Biejat, MD., 2. Diagnostic imaging and interventional procedures in children with congenital heart diseases - Agnieszka Biejat, MD., 3. Diagnostic imaging in urinary tract diseases in children - Anna Jakubowska, MD, 4. Iatrogenic complications due to the diagnostic imaging procedures in pediatrics – Andrzej Marciński MD, PhD, 5. Diagnostic imaging in gastrointestinal tract diseases in children – Michał Brzewski, MD. Topics of practical classes: 1. Radiological imaging procedures (workshop) – Anna Jakubowska, M.D., 2. Ultrasound examinations (workshop) – Michał Brzewski, M.D., Basic textbooks: J.O. Haller, T.L. Slovis: Pediatric Radiology. Springer, II nd ed. 12 LABORATORY DIAGNOSTICS Department of Laboratory Diagnostics Medical University Warsaw Address: 1a Banacha Street, 02 -009 Warsaw Phone: 022 599 24 05, fax: 022 599 21 04 e-mail dagna@amwaw.edu.pl Head: Prof. Dagna Bobilewicz MD, PhD Curricular affair: Prof. Dagna Bobilewicz, MD, PhD, Marta Faryna, MD, Justyna Kotlicka, MD, Marzena Iwanowska, MA Number of teaching hours: Lectures: 10 h Seminars 25 h Practical classes 15h Assessment of student performance; On completion of the course students are expected to take a final assessment test. The aim of the course The course program offers to students the basic information regarding: understanding the influence of different factors on the final laboratory results and assessing their utility including the cost/benefit ratio describing the application of laboratory tests for different clinical conditions and purposes performing some POCT (point of care tests) procedures understanding approach to “quality” in medical laboratory in the view of “ normal values” using this knowledge to adjust the laboratories’ operations to respond to changing demands of health care Topics of lectures 1. Clinical values of laboratory results as a function of preanalytical, analytical and postanalytical factors. 2. Interpretation of laboratory results. Reference values versus clinical decision limits. Evidence based laboratory medicine. 3. Role of the laboratory in blood transfusion. 4. Emergency laboratory. 5. Organisation of laboratory services. Lights and shadows of centralisation and POCT (point of care tests). Emergency laboratory. Topics of seminars 1. Disorders of water and electrolyte metabolism. 2. Coagulation and fibrinolysis disorders. 3. Haematology. Factors required for erythropoesis. White cells responses. Malignancies. 4. Blood group antigens. The compatibility between blood recipient and blood donor. 5. Clinical chemistry and enzymology tests in routine medical laboratory. 6. Total quality management systems in medical laboratories, choice or necessity? 7. Quality assurance. 8. Plasma proteins. Protein markers of diseases including tumour markers 9. Basic laboratory endocrinology. 10. Atherosclerosis. Laboratory coronary risk profile. Cardiac markers. 11. Bilirubin formation. Laboratory assessment of liver function. 12. Influence of acute phase and other proteins on interpretation of laboratory results. 13. Discrepancy of results obtained by different methods with emphasis on immunochemicaly determined parameters. 13 Topics of practical training 1. Blood gas and electrolyte status in different clinical conditions. Critical care tests - interpretation of results. 2. Automation in coagulation and haematology – interpretation of results. 3. Laboratory evaluation of erythrocytes and anaemia. Laboratory evaluation of leukocytes. (automatic and microscopic picture). 4. Blood groups and cross-match tests. 5. Laboratory tests in diagnosis and monitoring of diabetes. Role of patient self assessment in different clinical conditions. 6. Assessment of renal function. 7. Practical assessment of precision and accuracy, protocols from analysers and EQA (external quality assurance) providers. 8. Urinalysis, laboratory evaluation of body fluids components. Pregnancy tests. Basic text books Seminars in Clinical Biochemistry edited by Marek Dominiczak ,University of Glasgow (available on request) Clinical Laboratory Diagnostic L. Thomas T/M Books any other books available on Clinical Chemistry, edited after 1997 Tietz Fundamentals of Clinical Chemistry edited by CA. Burtis , ER Ashwood WB Saunders Company 2001 14 HYGIENE & EPIDEMIOLOGY Institute of Social Medicine Address: 3 Oczki Street, 02-007 Warsaw Phone: 022 621 51 97, Phone/fax: 022 621 52 56 Department of Epidemiology Head: Maria Mularczyk-Bal, MD, PhD Curricular affairs: Prof. Jan Kopczyński, MD, PhD, Maria Mularczyk MD, PhD, Anna Ziółkowska MD Classes will be held every Tuesday & Thursday 9.00-12.30 from 20.11 to 08.12.06 and from 02.01 to 19.01.07 Number of teaching hours: Lectures 15 hrs Seminars 15 hrs Practical classes 10 hrs Assessment of students’ performance: A test closing seminars & practical classes; a final oral exam. The aim of the course: To pass the knowledge regarding the means of enhancing health, identifying avoidable risks, detecting and curing early-stage diseases, reverting and delaying their debilitating and/or fatal outcomes. Topics of lectures: 1. Introduction – definition of health and determinants of health and disease 2. Public health, preventive medicine, national and world-wide health programmes. 3. The role of nutrition in the disease prevention. 4. Nutrition and Diet in the Diabetes Mellitus, Cardiovascular Disease, Hypertension, Osteoporosis, Obesity and Cancer (part one). 5. Nutrition and Diet in the Diabetes Mellitus, Cardiovascular Disease, Hypertension, Osteoporosis, Obesity and Cancer (part two). 6. Environmental health issues: air (part one) 7. Enivironmental health issues: water and soil (part two) 8. Occupational medicine. 9. Health promotion vs. prevention of illness. 10. Evaluation of community health; descriptive ways. 11. Natural history of diseases as a tool of prevention. 12. Disclosing the causes of illness; main avoidable risks. 13. World-wide health programmes; the local contribution. 14. Evaluating efficiency of intervention; controlled studies. 15. The future of health status based on recent evidence. Topics of seminars of Epidemiology 1. Health risks: their environmental, behavioural and intrinsic basis. 2. The levels of prevention: their influence on the risk of contracting a disease, its development and outcome. Behavioural roots of ill health: free choice vs. the pressure of 15 social attitudes & conditions.Tobacco smoking as a health problem. Other social scourges: the fight with alcohol & drug dependence. 3. Epidemiological approach towards medical problems; epidemioolofgical methods of heath monitoring: descriptive vs. analytical. 4. The population methods of elucidating etiology of diseases & health-related problems. 5. The sources of information regarding commumnity health. The mortality data: the number and causes of death; the rules of stating post-mortem diagnosis. The classification of diseases, injuries, poisoning & other health problems (ICD). The characteristics of the current revision of ICD: coding practices. 6. Application of mortality data to the assessment of community health: crude death rates, life expectancy, infant mortality, premature deaths. European & world patterns and trends in mortality. 7. The role of demographic events: cohort vs. age-related mortality. Overcoming of demographic events: age-sex-specific presentation, life tables, standardization of the rates. 8. The incidence of illness. 9. The role of reporting health events in the evaluation of the levels of illness. 10. The incidence trends in major infectious diseases: the major tenets of their control. The newer developments: the AIDS pandemic, Ebola outbreaks, returning of tubercle baccillus etc. 11. The prevalence of chronic illness: tuberculosis, cardiovascular diseases, cancer, nonspecific respiratory conditions, diabetes etc. 12. The hospital mortality statistics: their role in the assessment of health needs & demands. 13. Screening for disease: principles & practice. The disease-oriented approach towards early detection & treatment of major chronic diseases. Available diagnostic tools; their acceptability, validity and repeatability. Effectiveness of screening: examples of successful search for early-stage disease; pitfalls and limitations. 14. Searching for disease etiology. The potential of descriptive data, as the source of hypotheses. Principal methods of analytical epidemiology: case-control & cohort investigations. Analytical outcomes as the estimates of risk: absolute risk of a disease, relative risk, relative odds, etiological proportion. 15. Essentials of clinical epidemiology: preventive & clinical trials. The admissibility of human experimentation: the limits. Topics of practical classes of Preventive Medicine: 1. Energy requirements and classification of food products and their characteristics including recommended dietary allowances (RDA). 2. Selecting food products according to content of energy and other nutrients (using reference tables of nutritive values). 3. Calculating resting energy expenditure, total daily energy requirements and total daily energy expenditure. 4. Assessment of nutritional status: clinical examinations, laboratory investigations, anthropometric data: calculating BMI, waist/hip ratio, evaluation of fat tissue by skinfold measurements and body composition analyzer, evaluation of muscle tissue development with Frisancho index. 5. Planning proper diets in relation to age, sex, weight and physical activity and assessment of students’ diets (using a food composition computer program). 6. Basic physical properties of air and their physiological effects: pressure, temperature, humidity, motion and ionization. 7. Air contamination: gases, dust, acid rains, smog, ozone hole, greenhouse effect and sanitary examination of indoor and outdoor air 16 8. Hygienic conditions in closed rooms (dewelling house, operation theatre, school): microclimate, chemical contamination, microflora) 9. Water - Effect of human activities, general characteristic of drinking water 10. Sanitary examination of air and water Basic textbooks: 1. Friedman G.D. Primer of epidemiology (the latest edition). McGraw-Hill, New York, (available in the Institute). 2. Burton B.T., Foster W.R. Human nutrition (Formely The Heinz Handbok of Nutrition). Fourth Edition. McGraw-Hill 3. Eschelman M.M. Introductory nutrition and nutrition therapy. Third edition. Lippincot, Philadelphia, 1996. Complementary texbooks: 1. Ahrens W, Pigeot I. Handbook of Epidemiology. Springer-Verlag Berlin Heidelberg 2005 (selected chapters). 2. Jekel J.F., Elmore J.G., Katz D.L. Epidemiology, biostatistics and preventive medicine. WB Sounders Company., Philadelphia, 1996. 3. Jędrychowski W., Maugeri U. Epidemiologic methods in studying chronic diseases. International Center for Studies & Research in Biomedicine, Luxembourg, 2000. 4. www.bmj.com Search criteria: Title/Abstract:nutrition 17 INTERNAL MEDICINE Department of Family, Internal and Metabolic Medicine Address: 19/25 Stępińska Street, 00-739 Warsaw phone/fax: 022 318 63 25/022-318-63-25 Head: Prof. Kazimierz Wardyn, MD, PhD Curricular affairs: M. Olędzka-Oręziak, MD. Number of teaching hours: Lectures 20 Seminars 35 Practical Classes 35 Assessment of student performance: Attendance and activity during clinical classes, written case history (Grades 1-5 and “outstanding level”), final oral exam If the test is failed, the next step is a second oral exam. To check the date of this exam contact Dr.Olędzka-Oręziak within two weeks of the first exam. If the student does not contact Dr.Olędzka-Oręziak within the two weeks, the second exam will automatically be a failure. The two failures will then be reported to the Dean of the 2nd Faculty of Medicine. The aim of course: During the 4 weeks of the course, students are expected to learn history taking, physical examination, interpretation of laboratory results and the principles of the most common clinical procedures. Topics of lectures: 1. Overview of physical examination and history taking. Essentials of writing a case history 2. The comprehensive adult physical examination 3. The comprehensive adult health history - Review of Systems (ROS). 4. Digestive tract-symptoms. 5. Interpretation of basic laboratory values. 6. Basics of ECG part I. 7. Basics of ECG part II. 8. BMI and assessment of nutritional status. 9. Approach to the hepatic disorders. 10. Endocrinological diseases- hormones – mechanism of action 11. Neoplasms of the gastrointestinal tract. 12. Endocrinological diseases, symptoms and examination. 13. Examination in kidney disease. Part I 14. Examination in kidney disease. Part II 15. Fever – approach to the problem, pathophysiology, classification, differential diagnosis. 16. Nutrition in internal disease. 17. How to use information technology to access online medical information, manage information and assimilate evidence from scientific studies. 18. Arterial hypertension. 19. Problems with electrolyte balance. 20. Adapting your interview to specific situations. 18 Topics of seminars: 1. The comprehensive adult health history. Case records. 2. Examination of the head and neck. 3. Cardiovascular system - symptoms. 4. Cardiovascular system - physical examination part I 5. Cardiovascular system - physical examination part II 6. Respiratory system - symptoms. 7. Respiratory system - physical examination 8. Clinical symptomatology of emergency cardiac situations. Chest pain – approach to differential diagnosis based on different cases from our clinical ward. 9. Abdomen - physical examination. 10. Urinary tract - symptoms and physical examination. 11. Important elements of neurological examination 12. Examination in rheumatological diseases. 13. Unconscious patient – how to evaluate efficiently. 14. Abdominal pain – main steps in differential diagnosis - panel discussion with case presentation. 15. ABC's of practical procedures in internal medicine part I. 16. ABC's of practical procedures in internal medicine part II. 17. Patient with diabetes and its acute complications. 18. Examination in hematological diseases. 19. Spirometry - the most common use of the pulmonary function tests. 20. Adapting your interview to specific situations – case reports. Topics of classes: 1. Obtain a pertinent, relevant and problem-specific health history utilizing interviewing skills that are appropriate to the developmental, educational and cultural characteristics of the patient. 2. Present the findings of the history and physical examination in a clear, concise and organized manner using the problem oriented (SOAP) recording method In addition, students will also: * learn how to independently perform an EKG (including how to attach all leads, functioning of the EKG and subsequent analysis of the rhythm strip) * learn how to draw blood (utilizing each other as patients) * learn how to obtain a blood sugar * learn how to perform basic internal medicine procedures * present a case history of an actual patient from the clinical ward to the entire group of students and instructors (students will be divided into small groups by the instructors; student groups will be assigned one actual ward patient per group; students will take a complete history and physical; analyse all laboratory, EKG and other clinical data; students will then formulate a complete presentation that will involve a thorough assessment of the disease process and plan of treatment for this patient - SOAP format should be followed) This case presentation will be graded. Basic textbooks: 1. Harrison’s Principles of Internal Medicine by Dennis L. Kasper, Eugene Braunwald, Anthony Fauci, Stephen Hauser, Dan Longo, J. Jameson; Mc Graw-Hill Professional; 7th edition. 2008 2. Bates’ Guide to Physical Examination and History Taking, by Lynn S. Bickley,Peter G. Szilagyi, Lippincott Williams & Wilkins Publishers; 10th edition, 2008; 19 SURGERY 2nd Chair and Department of General, Vascular and Oncological Surgery. Address: 19/25 Stępińska Street, 00-739 Warsaw Phone/fax: 022 841 15 92, 022 31 86 391; deptsurg@polbox.pl Head: Prof. Jerzy A. Polański, MD, Ph.D. Curricular affairs: Paweł Białek MD, Ph.D. Number of teaching hours: The course covers 60 hours of instructions, divided as below: Seminars- 20 hr Practical classes- 40 hr Teaching time: 8.00 am- 1.00 pm. Assessment of student performance: On completion of the course student are expected to take a final test. The aim of the course: The program is based on teaching students general surgery knowledge including perioperative diagnosis, surgical treatment and postoperative care. Students have a oportunity to participate in outpatient unit work. Topics of seminars: 1. Preoperative and postoperative problems in surgical patient care. 2. Surgical wound care and surgical technique. 3. Hernias of the groin. 4. Head, thoracic and abdominal trauma. 5. Acute upper gastrointestinal bleeding. 6. Acute pancreatitis. 7. Gallstones and chronic cholecystitis. 8. Colonic cancer. 9. Surgical anatomy of the low extremity veins. Thrombophlebitis. DVT.ST. Topics of practical classes: 1. Bed-side teaching 2. Assisting at the operations 3. General surgery out-patient therapy participation Basic textbooks: 1. „Current Surgical Diagnosis and Treatment” Lawrence W. Way, 10th edition or older one. 20 MEDICAL PSYCHOLOGY Department of Medical Psychology Address: 2 Księcia. Trojdena Street, 02-091 Warsaw Phone: 022 57 20 533; fax: 022 57 20 542; e-mail: zpm@wum.edu.pl Head: Professor Krzysztof Owczarek Curricular affairs: Joanna Chylińska, e-mail: joanna.chylinska@wum.edu.pl Magdalena Lazarewicz, e-mali: magdalena.lazarewicz@wum.edu.pl Number of teaching hours: The course covers 30 hours of instruction, divided as below: - seminars 10 hrs - practical classes - 20 hrs Assessment of student performance: Students’ performance is continually assessed throughout the course. Regular class attendance is mandatory. However, if students are absent from a seminar, they are required to answer additional test questions, covering a particular topic, during the test. Passing grades are granted to students who have successfully passed the assessment test. The aim of the course: Students are acquainted with selected psychological concepts to broaden their appreciation of psychological mechanisms underlying patients’ behaviour. They are encouraged to become sensitive to the emotional needs of the patient, to improve their skills with respect to relating to the patient both verbally and emotionally, to be aware of dangers of iatrogenic errors and to learn how to avoid them. Students become skilled in detecting psychological problems contributing to the onset and development of the patient’s illness as well as problems impeding treatment. Students are also taught appropriate techniques of conducting a psychosomatic interview and establishing a psychosomatic diagnosis. The aim of the course is also to sensitize students to the psychological problems of incurably and terminally ill patients and their families. Topics of seminars: 1. Psychology: the study of humans (introduction). 2. The contribution of psycho-social factors to somatic disease, Part I: stress: basic concepts and approaches, salutory and pathological consequences of stress, disease and treatment as stressors: psychological analysis of the patient situation. 3. The contribution of psycho-social factors to somatic disease, Part II: situational and personality risk factors in somatic disease, type A behaviour, selected interpretations of the contributions of psycho-social factors to the onset of somatic disease. Topics of practical classes: 1. Psychological Consequences of Somatic Disease: effects of disease and hospitalization on human functioning, Attitudes Towards Illness (ATI). 2. Psychological Aspects of Treatment of the Somatic Patient – Part I: 21 3. 4. 5. 6. 7. the essence of doctor – patient relationship, models of Doctor - Patient relationship, principles underlying development of good doctor-patient relationship. Psychological Aspects of Treatment of the Somatic Patient 2 – Part II: iatrogenic errors barriers of interpersonal communication, appropriate information, selected aspects of psychosomatic diagnosis. Death and Dieing: discussion based on the presented documentary programme. Test. Role-playing exercises, Part I: the opportunity to practice doctor-patient relationship techniques. Role-playing exercises, Part II: the opportunity to practice doctor-patient relationship techniques; Closing remarks. Basic textbook: Wrześniewski K., Skuza, B. (eds. ). Psychosomatic Medicine and Psychology of Somatically Ill: Selected Issues. Warsaw: Warsaw Medical Academy Edition, 2000. Complementary textbooks: Additional reading materials are provided by lecturers during the course. 22 POLISH LANGUAGE Foreign Language Center Department of the Medical University of Warsaw Address: The Didactic Center, 2a, Trojdena Street, 02-109 Warsaw Phone: 022 5720863, fax: 022 5720864 ; e-mail: sjosekretariat@wum.edu.pl Head: Joanna Ciecierska MA Curricular affairs: Maria Janowska MA, Świetlana Sikorska MA, Małgorzata Kierepka MA Number of teaching hours: The course covers 80 hours of classes:45 hours in autumn semester and 35 hours in spring semester. Assessment of student performance: To obtain a credit after each term a student has to attend classes regularly and pass all the assigned written tests successfully (minimum score is 55% correct answers). Please be informed, that according to the academic rules students are obliged to take part in all the classes. Classes start punctually according to the timetable. Students coming late (more than 10 minutes after the time) will not be allowed into the classroom and this will be treated as unexplained absence. No absence will be accepted except the one for which a student has a valid medical note. The note must be submitted to the teacher within three days from the visit to the doctor. A student’s absence on the assigned day of the test will result in not obtaining a credit. Students who fail the test can be given a chance to sit a retake test twice, provided they took part in classes regularly. The days of the retake tests are set by the teacher in agreement with the Dean’s Office. The first retake can be not earlier than a week from the day of the test. The second retake can be not earlier than two weeks from the day of the first retake and not later than the last day before the retake examination session. The result of the second retake is the final mark the student receives. There are no more possibilities of any other retakes. The student who fails the second retake must repeat the part of the programme he/she has failed. The aim of the course Second year students are expected to their skills in Polish Language, master basic medical terminology and be able to communicate with the patient at the bedside(ask simple questions and give instructions). Topics of classes: 1. Review of the basic language structures and vocabulary introduced during the first year of studies. 2. Hospital vocabulary. Dative Case. 3. Medical specialities and specialists. 4. At the doctor’s surgery.(Giving information about health. Asking for assistance). 5. The human body: parts of the human body cavities and organs they contain systems and organs and the most common diseases of the systems(signs, symptoms and diagnostic tests). 6. Examining an adult patient- doctor’s instructions. 23 Proszę + Perfect and Imperfect Infinitives. 7. Examining a paediatric patient- doctor’s instructions to a child. Imperative Mood. 8. Basic bedside conversations: -greeting a patient - introducing oneself to a patient -asking some general questions -taking the patient’s history( short version) - examining the patient: giving instructions and making comments. Basic textbook: Maria Janowska, Świetlana Sikorska “Proszę oddychać. Part I” Complementary materials: Handouts prepared by the teachers. 24 SUMMER CLINICAL CLERKSHIPS The summer clinical clerkships are mandatory for students to be assigned a pass for the whole year’s academic performance since they are an inherent part of the medical instruction provided throughout the year of study. Upon completion of the second year students are required to have one-month clinical clerkships at a teaching hospital in Poland or selected foreign countries. The curriculum of clinical clerkship comprises: a) a two-week training in the internal medicine ward, b) a two-week training in the pediatric ward. The head of the ward or an appointed assistant is responsible for providing a detailed program of the training and scheduled duties as well as supervision of students’ clinical performance. Students carry out the work which is that of a regular physician and are supervised by a physician in charge. During the training students are obliged to have four twenty-four-hour shifts (two in each ward) when they accompany the doctor on duty while he/she performs all the necessary clinical activities and procedures. The goal of the clinical instruction is to make a practical use of the knowledge acquired in the course of the study e.g., bacteriology, virology, pathomorphology, pathophysiology, pharmacology, and particularly of the clinical subjects i.e. introduction, to medicine and pediatrics. The clinical instruction should include the following aspects: 1. information about the organization of medical and pediatric ward and their cooperation with the outpatients’ department, 2. further improvement in taking histories and performing physical examination, particularly concerned with assessment of patients’ general condition and their psychology, 3. planning and collecting specimens for accessory investigations and interpretation of the results, 4. improving the skills in differentiating and diagnostic basic clinical entities, particularly acute cases, and principles of treatment, 5. providing first aid, 6. performing everyday clinical procedures (injections and intravenous infusions, catheterization, lumbar puncture, bone marrow puncture and paracentesis of the body cavities), 7. participation in ward rounds and consultations by other specialists. In the pediatric ward there are additional requirements: 1. treatment of pediatric patients with regard to their age and natural or artificial feeding, 2. calculation of nutritional requirements, fluid supply, drug dosage, 3. taking a history, performing physical examination with regard to the developmental age, 4. knowledge of the vaccination and immunization schedule, 5. knowledge of sanitary and epidemiological rules in the neonatal and pediatric wards and ways of preventing hospital infections. Throughout the course of the training students are expected to make records of their activities and procedures performed. They are also assessed by the instructor in charge and are finally granted their passing mark by the head of the department. Certificates written in English or translated should be submitted to the Dean’s Office of the Medical University of Warsaw by October 5th of the subsequent academic year. 25