Philadelphia University
Faculty of -Pharmacy
Department of Clinical Sciences
First Semester, 2010/2011
Course Syllabus
Course Title: Pharmacology
Laboratory
Course Level: Third year
Lecture Time: 2pm
Course code:0511325
Course prerequisite (s) and/or corequisite
(s):Pharmacology 1 (0511310)
Credit hours: 1 hours
Academic Staff Specifics
Name
Prof. Husni
Twaij
Rank
Office Number and
Office
Location
Hours
Daily
Professor
522
E-mail Address
htwaij@hotmail.com
from1011
htwaij@philadelphia.edu.jo
Course module description:
-This course is complementary part to the theoretical lectures provided by the corequisite course Pharmacology I,II & III . This course is designed to allow students to
learn how to behave with animals by knowing the mechanism of handling and learn
the different routes of administration of drugs and the onset of action by each route;
Course module objectives:
At the end of this module, student will be able to:
1. Learn the mechanism of handling of animal as (Rabbit, Mice, and Rat).
2. Learn how to make calculation of the dose of each drug depending on different
variable.
3. Know the mechanism of action of many drugs.
4. Learn the different routes of administration and the onset of action of each route.
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Course/ module components

Books (title , author (s), publisher, year of publication)
1. Pharmacological Experiments on Isolated Preparations. By the staff of the
Department of Pharmacology, University of Edinburgh.
In addition to the above, the lecturer will provide the students with handout



Support material (s) (VCs, aces, etc).
Study guide (s) (if applicable)
Homework and laboratory guide (s) if (applicable).
Teaching methods:
Lectures, discussion groups, tutorials, problem solving, debates, etc.
Learning outcomes:
 Knowledge and understanding: They will know the mechanism of action of different
drugs and there uses for example the drugs of hypertension.
 Cognitive skills (thinking and analysis).
Possess self learning skills, problem solving & critical thinking abilities.
Interpret, analyze & evaluate information in the literature
 Communication skills (personal and academic).
Write clear concise & organized communication. Give oral presentation to small &
large groups.

Practical and subject specific skills (Transferable Skills).
Student will apply most of the acquired knowledge from the theoretical lectures in
this co requisite practical laboratory.
Assessment instruments




Short reports and/ or presentations, and/ or Short research projects
Quizzes.
Home works
Final examination: 50 marks
Allocation of Marks
Assessment Instruments
Mark
Mid –Term Exam
30%
Assignment /Quizzes /Tutorial
20%
Final
examination:
verbal,hand ins …etc..
(Comprehensive,
Total
written, 50%
100%
2
Documentation and academic honesty
 Documentation style (with illustrative examples)
 Protection by copyright
 Avoiding plagiarism.
Course/module academic calendar
week
(1)
(2)
(3)
Basic and support
material to be
covered
Handling
Experimental
Animals and Routes
of drug
administration.
Absorption
and
Excretion of Drugs;
Absorption
of
Pentylene Tetrazole
The
effect
of
Ionisation on the
absorption of drugs.
Drug metabolism.
(4)
Drug
Antagonism;
The response of
human
skin
to
Histamine
and
Adrenaline.
(5)
Pharmacological
experiments
on
isolated preparation.
Dose
response
relationship.
(6)
First examination
(7)
(8)
(9)
(10)
Testing of Analgesics
The
effect
of
parasympathetics on
the
glandular
secretion
Insulin hypoglycemic
shock
Preparation
of
3
Homework/reports and
their due dates
(11)
Second examination
(12)
(13)
(14)
(15)
Specimen examination
(Optional)
animals for recording
blood pressure.
Drugs & human eyes
Screening
of
antidiabetic agents on
rabbit and mice by
using alloxan diabetic
animals
Screening of antiulcer agents.
General anesthesia (
Ether
&
/or
chloroform on test
and control mice
Antihypertensive
agents; Study the
effects of sympathetic
drugs
&
their
antagonists on rats,
using a physiographe.
(16)
Final Examination
Expected workload:
On average students need to spend 2 hours of study and preparation for each 50-minute
lecture/tutorial.
Attendance policy:
Absence from lectures and/or tutorials shall not exceed 15%. Students who exceed the 15% limit
without a medical or emergency excuse acceptable to and approved by the Dean of the relevant
college/faculty shall not be allowed to take the final examination and shall receive a mark of
zero for the course. If the excuse is approved by the Dean, the student shall be considered to have
withdrawn from the course.
Module references
Books
Students will be expected to give the same attention to these references as given to the
Module textbook(s)
1. The Pharmacological basis of therapeutics. By Joel G. Hardman, Lee E. Limbird,
Perry B.Molinoff, Raymond W. Ruddon and Alfred Goodman Gillman. 9th edition
(1996). McGraw –Hill. ISBN0-07-113348-8.
2. Textbook of pharmacology by W. C Bowman and M.J. Rand Publisher: Blackwell
Science; 2nd edition (June 1, 1980) ASIN: 0632099909
Website(s):
http://www.philadelphia.edu.jo/pharmacy/resources.html
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