UNIVERSITY OF KENTUCKY
COLLEGE OF NURSING
A Web Course
Title: Advanced Pharmacologic Applications in Primary Care
Credit Hours: 3 Credit Hours
Pre- or Co Requisite: Graduate status and Graduate pathophysiology course.
Course Description: This course is designed to prepare clinical nurse specialists,
NPs, NS, and midwives to accurately describe, administer, and counsel patients
regarding appropriate and safe medication regimens. In addition nurse practitioners,
nurse midwives and clinical nurse specialist will be prepared medication
prescriptive authority within their scope of practice. Basic pharmacologic principles
and the pharmacologic actions of the major drug classes will be discussed in relation
to physiologic systems, with emphasis on the application of these agents.
Course Objectives: Upon completion of the course, the students will be able to:
1. Explain the basic principles of pharmacology and pharmacotherapeutics.
2. Describe the most commonly prescribed agents in the major drug classes.
3. Explain the mechanism of action of the major drug classes.
4. Analyze the adverse effect and drug interaction profiles of the major drug
classes and individual drugs within these classes.
5. Make appropriate therapeutic treatment decisions for individual patients
utilizing drugs from the major drug classes.
6. Apply the laws governing the prescribing of drugs when writing prescriptions.
FACULTY:
Mikael D. Jones, Pharm.D., BCPS
Assistant Professor
Colleges of Nursing and Pharmacy
Room 302
College of Pharmacy
University of Kentucky
Lexington, KY 40536-0082
Phone: 859-257-6265 Email: mjone5@email.uky.edu
All questions about course content should be directed to Dr. Jones. He will respond with
in 24-48 hours. If you have not received a response in that time frame please contact him
again as the message might not have reached him. For technical assistance during the
Web course contact Melissa Bolin at melissa.bolin@uky.edu or 859-323-3851.
1
TEACHING/LEARNING METHODS: This is a self-directed learning using core
PowerPoint presentations, Word documents, Web sites, and case solving activities.
Students must have access to computer facilities, the Internet, a web browser that is
equivalent to Internet 5 Explorer or higher, email address, and a printer.
EVALUATION:
Examinations and Evaluations: Each unit will have an examination consisting of 10
multiple choice questions. A comprehensive final must also be completed at the end
of the course. The questions will test both understanding and application of the unit
material.
GRADING SCALE:
Unit Examinations (14 units X 10 points each) 140 points
Final Assessments
70 points
________
TOTAL
210 points
The total score will be reported to your institution as a percentage. Your institution will
assign the final letter grade that you earned for the course.
Class Times: This course is a web course and will use a distance learning format. The
course will be taught via the Web-enhanced format utilizing the assigned websites, core
PowerPoint presentation, Word documents, textbook reading assignments and other selfdirected learning activities.
Suggested Texts:
Reading assignments made from the Katzung textbook Basic and Clinical
Pharmacology are intended to supplement student comprehension of assigned
Learning Units.
Finkel (2009). Lippincott's Illustrated Reviews: Pharmacology ,4th edition, Lippincott W&W ISBN
0781771552; Price $59.95
This textbook provides general overview of each drug class. The book uses many diagrams, graphs,
and pictures to help illustrate the pharmacology of each drug class.
11th Edition (2010) Drug Information Handbook for Advanced Practice Nursing. Lexi-Comp, Inc.
ISBN 978-1-59195-281-7 ; Price $49.95
This is a well-known drug information resource and the goal of this text is to help students
recognize and use appropriate resources for drug information. Students will not be assigned specific
readings from the handbook. However students are encouraged to use the handbook throughout
each unit to appreciate how the pharmacology relates to the use of a medication in clinical practice.
Students may use this book during module quizzes.
2
OPTIONAL TEXTS
Chisholm-Burns (2010). Pharmacotherapy Principles and Practice, 2 Edition, McGraw-Hill. ISBN
0071621806; Price $149
This textbook provides detailed chapters on the pharmacotherapeutics of various disease states. This
book will provide excellent examples of how pharmacology knowledge is applied to the care of a
patient for rational drug treatment. Optional reading assignments from the Chisholm-Burns
textbook Pharmacotherapy Principles and Practice will be provided for each unit.
Katzung (2009). Basic and Clinical Pharmacology, 11th Edition. Lange Medical Books,
McGraw-Hill. ISBN 0071604057; Price $64.95
This textbook provides detailed chapters of the pharmacology of various drug classes. The
book is very detailed and is would be helpful to a student that requires more depth into
pharmacology or does not have much familiarity with the subject.
Core Learning Unit Materials: Units will be available online with continued
availability. Assigned readings in the Katzung text are intended to supplement
student comprehension of assigned Learning Units.
3
TENTATIVE COURSE SCHEDULE
Unit 1
Unit 2
Unit 3
Unit 4
Assignments
Web-based material
Required Textbook Reading Chapters 1
and 2 in Lippincott’s Illustrated Review:
Pharmacology
Optional Textbook readings: Chapter 1
in Pharmacotherapy Principles and
Practice
Chapters 1-4 in Katzung
Topics
Basic Principles of Pharmacology and
Therapeutics
Web-based materials
Required Textbook Reading Chapters
30,31,32, and 33 in Lippincott’s
Illustrated Review: Pharmacology
Optional Textbook readings Chapters 69,
71, 72, and 79 in Pharmacotherapy
Principles and Practice
Chapters 43-46, 50 and 51in Katzung
Anti-Infectives I
1. Antibiotics
Web-based materials
Required Textbook Reading Chapters 35
and 38 in Lippincott’s Illustrated Review:
Pharmacology
Optional Textbook readings Chapters 83,
84, and 87 in Pharmacotherapy
Principles and Practice
Chapters 48-49 in Katzung
Web-based materials
Required Textbook Reading Chapters 19
and 22 in Lippincott’s Illustrated Review:
Pharmacology
Anti-Infectives II
1. Antifungals
2. Antivirals
Cardiovascular and Renal Systems I
1. Antihypertensive agents
Optional Textbook readings Chapters 5
and 6 in Pharmacotherapy Principles
and Practice
Chapters 11, 17 (pgs 293-293), and 15 in
Katzung
4
Web-based materials
Required Textbook Reading Chapters 16
and 18 in Lippincott’s Illustrated
Review: Pharmacology
Unit 5
Unit 6
Unit 7
Unit 8
Cardiovascular and Renal Systems II
1. Drug used in Congestive heart failure
2. Agents used in Angina and
Myocardial Infarction
Optional Textbook readings Chapters 7
and 8 in Pharmacotherapy Principles and
Practice
Chapters 12,and 13, and 17 (pgs 301-303)
in Katzung
Web-based materials
Required Textbook Reading Chapters 20
(pp 245-247) and 21 in Lippincott’s
Illustrated Review: Pharmacology
Optional Textbook readings Chapters 12
and 66 in Pharmacotherapy Principles
and Practice
Chapters 33 and 35 in Katzung
Hematologic system I
1. Agents used Anemias
2. Agents used in Dyslipidemias
Web-based materials
Required Textbook Reading Chapter 20
(pp 229-245) in Lippincott’s Illustrated
Review: Pharmacology
Optional Textbook readings Chapters 10
and 11 Pharmacotherapy Principles and
Practice
Chapter 34 in Katzung
Hematologic System II
1. Thromboembolic disorders
2. Miscellaneous hematologic disorders
Web-based materials
Required Textbook Reading Chapters 27
and 42 (pp 521-524) in Lippincott’s
Illustrated Review: Pharmacology
Optional Textbook readings Chapters 14,
15, and 62 Pharmacotherapy Principles
and Practice
Chapters 9 (pgs 127-128, 130-131, 137),
16 (pgs 275-279), and 20 in Katzung
Respiratory System
1. Asthma/COPD
2. Allergic rhinitis
3. Cough/Cold
5
Unit 9
Unit 10
Web-based materials
Required Textbook Reading Chapters 23
(pp280-284) and 24 in Lippincott’s
Illustrated Review: Pharmacology
Optional Textbook readings Chapters
43and 44 in Pharmacotherapy
Principles and Practice
Chapters 38 and 41 in Katzung
Web-based materials
Required Textbook Reading Chapters 25
and 29 (pp. 343-344) in Lippincott’s
Illustrated Review: Pharmacology
Optional Textbook readings Chapters
48, 49, 50, and 56in Pharmacotherapy
Principles and Practice
Endocrine System
1. Thyroid disorders
3. Diabetes
Reproductive System
1. Hormone Replacement Therapy
2. Hormonal Contraceptives
3. Menstrual Disorders
4.Osteoporosis
Chapter 40 and 42 in Katzung
Unit 11
Unit 12
Unit 13
Web-based materials
Required Textbook Reading Chapter 28
in Lippincott’s Illustrated Review:
Pharmacology
Optional Textbook readings Chapters
17, 18, 20, 21 in Pharmacotherapy
Principles and Practice
Chapter 62 in Katzung
Gastrointestinal System
1. Nausea /Vomiting
2. Diarrhea/Constipation
3. Peptic Ulcer
4. GERD
Web-based materials
Required Textbook Reading Chapters 8
(pp. 93-102) and 15 in Lippincott’s
Illustrated Review: Pharmacology
Optional Textbook readings Chapters
30, 31, and 32 in Pharmacotherapy
Principles and Practice
Chapters 21, 24, and 28 in Katzung
Nervous System I
1. Seizure Disorders
2. Parkinsonism and other movement
disorders
Web-based materials
Required Textbook Reading Chapters 23
and 24 in Lippincott’s Illustrated
Review: Pharmacology
Optional Textbook readings Chapters
37, 38, 40, 41 and 42 in
Pharmacotherapy Principles and
Practice
Chapters 22, 29, and 30 in Katzung
Nervous System II
1. Antipsychotic agents and Lithium
2. Antidepressant Agents
3. Sedative-hypnotic Agents
6
Unit 14
Web-based materials
Required Textbook Reading Chapters
14, 41 (pp.499-510), and 42 (524-527) in
Lippincott’s Illustrated Review:
Pharmacology
Optional Textbook readings Chapters
33, 34, 58 in Pharmacotherapy
Principles and Practice
Chapters 31 and 36 in Katzung
Nervous System III
1. Opioid analgesics and antagonists
2. NSAIDS
UNITS: Each unit will consist of objectives, study questions, a core PowerPoint
presentation (or Word document), textbook reading assignments and web-based material.
7