Genentech Publications on SPDI Genes
Updated 9/29/03 Hilary Clark
(Aliprantis 2000), (Chen 2000), (Gewirtz 2001), (Ghilardi 2002), (Gurney 1999),
(Holcomb 2000), (Humke 2000), (LeBlanc 2003), (LeCouter 2001), (Lee 2001), (Li
2000), (Lu 1999), (Mao 1999), (Marsters 1997), (Marsters 1997) (Marsters 1998),
(Pennica 1998), (Pitti 1998), (Sheridan 1997), (Stone 1999), (Szeto 2001), (Xie 1999),
(Xie 2000), (Yan 2000), (Yang 1998), (Yu 2000)
Aliprantis, A. O., Yang, R.B., Weiss, D.S., Godowski, P., and Zychlinsky, A. (2000).
"The apoptotic signaling pathway activated by Toll-like receptor-2." EMBO Journal
19(13): 3325-3336.
Chen, Q., Ghilardi, N., Wang, H., Baker, T., Xie, M.H., Gurney, A., Grewal, I.S., and de
Sauvage, F.J. (2000). "Development of Th1-type immune responses requires the type I
cytokine receptor TCCR." Nature 407(6806): 916-920.
Gewirtz, A. T., Navas, T.A., Lyons, S., Godowski, P.J., and Madara, J.L. (2001).
"Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce
epithelial proinflammatory gene expression." Journal of Immunology 167(4): 1882-1885.
Ghilardi, N., Li, J., Hongo, J.A., Yi, S., Gurney, A., and de Sauvage, F.J. (2002). "A
novel type I cytokine receptor is expressed on monocytes, signals proliferation, and
activates STAT-3 and STAT-5." J. Biol. Chem. 277(19): 16831-16836.
Gurney, A. L., Marsters, S.A., Huang, A., Pitti, R.M., Mark, M., Baldwin, D.T., Gray,
A.M., Dowd, P., Brush, J., Heldens, S., Schow, P., Goddard, A.D., Wood, W.I., Baker,
K.P., Godowski, P.J., and Ashkenazi, A. (1999). "Identification of a new member of the
tumor necrosis factor family and its receptor, a human ortholog of mouse GITR." Curr.
Biol. 9(4): 215-218.
Holcomb, I. N., Kabakoff, R.C., Chan, B., Baker, T.W., Gurney, A., Henzel, W., Nelson,
C., Lowman, H.B., Wright, B.D., Skelton, N.J., Frantz, G.D., Tumas, D.B., Peale, F.V.,
Shelton, D.L., and Hebert, C.C. (2000). "FIZZ1, a novel cysteine-rich secreted protein
associated with pulmonary inflammation, defines a new gene family." EMBO J. 19(15):
4046-4055.
Humke, E. W., Shriver, S.K., Starovasnik, M.A., Fairbrother, W.J., and Dixit,V.M.
(2000). "ICEBERG: a novel inhibitor of interleukin-1beta generation." Cell 103(1): 99111.
LeBlanc, H. N. a. A., A. (2003). "Apo2L/TRAIL and its death and decoy receptors." Cell
Death and Differentiation 10: 66 - 75.
LeCouter, J., Kowalski, J., Foster, J., Hass, P., Zhang, Z., Dillard-Telm, L., Frantz, G.,
Rangell, L., DeGuzman, L., Keller, G.A., Peale, F., Gurney, A., Hillan, K.J., and Ferrara,
N. (2001). "Identification of an angiogenic mitogen selective for endocrine gland
endothelium." Nature 412(6850): 877-884.
Lee, J., Ho, W.H., Maruoka, M., Corpuz, R.T., Baldwin, D.T.,Foster, J.S., Goddard,
A.D., Yansura, D.G., Vandlen, R.L., Wood, W.I., and Gurney, A.L. (2001). "IL-17E, a
Novel Proinflammatory Ligand for the IL-17 Receptor Homolog IL-17Rh1." J. Biol.
Chem. 276(2): 1660-1664.
Li, H., Chen, J., Huang, A., Stinson, J., Heldens, S., Foster, J., Dowd, P., Gurney, A.L.,
and Wood,W.I. (2000). "Cloning and characterization of IL-17B and IL-17C, two new
members of the IL-17 cytokine family." Proc. Natl. Acad. Sci. U.S.A. 97(2): 773-778.
Lu, Y., Brush, J., and Stewart,T.A. (1999). "NSP1 defines a novel family of adaptor
proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal
kinase/stress-activated protein kinase signaling pathway." J. Biol. Chem. 274(15): 1004710052.
Mao, W., Yu, X.X., Zhong, A., Li, W., Brush, J., Sherwood, S.W., Adams, S.H., and Pan,
G. (1999). "UCP4, a novel brain-specific mitochondrial protein that reduces membrane
potential in mammalian cells." FEBS Lett. 443(3): 326-330.
Marsters, S. A., Ayres, T. M., Skubatch, M., Gray, C. L., Rothe, M., and Ashkenazi, A.
(1997). "Herpesvirus entry mediator, a member of the tumor necrosis factor receptor
(TNFR) family, interacts with members of the TNFR-associated factor family and
activates the transcription factors NF-kappaB and AP- 1." J Biol Chem 272: 14029-32.
Marsters, S. A., Sheridan, J.P., Pitti, R.M., Brush, J., Goddard, A., and Ashkenazi, A.
(1998). "Identification of a ligand for the death-domain-containing receptor apo3." Curr.
Biol. 8(9): 525-528.
Marsters, S. A., Sheridan, J.P., Pitti, R.M., Huang, A., Skubatch ,M., Baldwin, D., Yuan,
J., Gurney, A., Goddard, A.D., Godowski, P., and Ashkenazi, A. (1997). "A novel
receptor for Apo2L/TRAIL contains a truncated death domain." Curr. Biol. 7(12): 10031006.
Pennica, D., Swanson, T.A., Welsh, J.W., Roy, M.A., Lawrence, D.A., Lee, J., Brush, J.,
Taneyhill, L.A., Deuel, B., Lew, M., Watanabe, C.,Cohen, R.L., Melhem, M.F., Finley,
G.G., Quirke, P., Goddard, A.D.,Hillan, K.J., Gurney, A.L., Botstein, D., and Levine,
A.J. (1998). "WISP genes are members of the connective tissue growth factor family that
are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon
tumors." Proc. Natl. Acad. Sci. U.S.A. 95(25): 14717-14722.
Pitti, R. M., Marsters, S.A., Lawrence, D.A., Roy, M., Kischkel, F.C., Dowd, P., Huang,
A., Donahue, C.J., Sherwood, S.W., Baldwin, D.T., Godowski, P.J., Wood, W.I., Gurney,
A.L., Hillan, K.J., Cohen, R.L., Goddard, A.D., Botstein, D., and Ashkenazi, A. (1998).
"Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer."
Nature 396(6712): 699-703.
Sheridan, J. P., Marsters, S.A., Pitti, R.M., Gurney, A., Skubatch, M.,Baldwin, D.,
Ramakrishnan, L., Gray, C.L., Baker, K., Wood, W.I., Goddard, A.D., Godowski, P., and
Ashkenazi, A. (1997). "Control of TRAIL-induced apoptosis by a family of signaling and
decoy receptors." Science 277(5327): 818-821.
Stone, D. M., Murone, M., Luoh, S., Ye, W., Armanini, M.P., Gurney, A., Phillips, H.,
Brush, J., Goddard, A., de Sauvage, F.J., and Rosenthal, A. (1999). "Characterization of
the human suppressor of fused, a negative regulator of the zinc-finger transcription factor
Gli." J. Cell. Sci. 112(Pt 23): 4437-4448.
Szeto, W., Jiang, W., Tice, D.A., Rubinfeld, B., Hollingshead, P.G.,Fong, S.E., Dugger,
D.L., Pham, T., Yansura, D.G., Wong, T.A., Grimaldi, J.C., Corpuz, R.T., Singh, J.S.,
Frantz, G.D., Devaux, B., Crowley, C.W., Schwall, R.H., Eberhard, D.A., Rastelli, L.,
Polakis, P., and Pennica, D. (2001). "Overexpression of the retinoic acid-responsive gene
Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid." Cancer
Res. 61(10): 4197-4205.
Xie, M. H., Aggarwal, S., Ho, W.H., Foster, J., Zhang, Z., Stinson, J., Wood, W.I.,
Goddard, A.D., and Gurney,A.L. (2000). "Interleukin (IL)-22, a Novel Human Cytokine
That Signals through the Interferon Receptor-related Proteins CRF2-4 and IL-22R." J.
Biol. Chem. 275(40): 31335-31339.
Xie, M. H., Holcomb, I., Deuel, B., Dowd, P., Huang, A., Vagts, A.,Foster, J., Liang, J.,
Brush, J., Gu, Q., Hillan, K., Goddard, A., and Gurney,A.L. (1999). "FGF-19, a novel
fibroblast growth factor with unique specificity for FGFR4." Cytokine 11(10): 729-735.
Yan, M., Wang, L.C., Hymowitz, S.G., Schilbach, S., Lee, J., Goddard, A., de Vos, A.M.,
Gao, W.Q., and Dixit, V.M. (2000). "Two-amino acid molecular switch in an epithelial
morphogen that regulates binding to two distinct receptors." Science 290(5491): 523-527.
Yang, R. B., Mark, M.R., Gray, A., Huang, A., Xie, M.H., Zhang, M., Goddard, A.,
Wood, W.I., Gurney, A.L., and Godowski, P.J. (1998). "Toll-like receptor-2 mediates
lipopolysaccharide-induced cellular signalling." Nature 395(6699): 284-288.
Yu, X. X., Mao, W., Zhong, A., Schow, P., Brush, J., Sherwood, S.W., Adams, S.H., and
Pan, G. (2000). "Characterization of novel UCP5/BMCP1 isoforms and differential
regulation of UCP4 and UCP5 expression through dietary or temperature manipulation."
FASEB Journal 14(11): 1611-1618.