MUTATIONS TAKS QUESTIONS SPRING 2003 – 10: (22) The diagram represents the chromosomes of a person with a genetic disorder caused by nondisjunction, in which the chromosomes fail to separate properly. Which chromosome set displays nondisjunction? F2 G8 H* 21 J 23 SPRING 2003 – 10: (26) The chain above represents three codons. Which of the following changes would be expected in the amino acid chain if the mutation shown above occurred? F The amino acid sequence would be shorter than expected. G* The identity of one amino acid would change. H The amino acid sequence would remain unchanged. J The identities of more than one amino acid would change. APRIL 2004 – 10: (26) Ultraviolet radiation can cause mutations in the DNA of skin cells that have been overexposed to the sun. This mutated DNA has no effect on future offspring because — F changes in skin cell DNA are homozygous recessive G mutations must occur within the RNA codons H offspring reject parental skin cells J* only changes to gamete DNA can be inherited APRIL 2004 – 11: (22) Mutations in DNA molecules can occur when — F replication of DNA is exact G a DNA enzyme attaches to an RNA codon H RNA codons are replaced by DNA nucleotides J* a change occurs in DNA nucleotide bases JULY 2004 – 11: 27 The assembly of a messenger RNA strand that normally begins with UAC has been changed so that the newly assembled messenger RNA strand begins with UAG. Which of the following will most likely occur? A The protein will be missing the first amino acid. B The amino acids that make up the protein will all be different. C The mRNA will become attached to a ribosome. D* The production of the protein will be stopped. OCTOBER 2005 – 11: 15 Which of the following is best supported by the information above? A Mutations located on chromosome 17 will result in cancer. B Cancerous growth will cause a mutation in some BRCA1 alleles. C* Mutated BRCA1 alleles are only one factor involved in cancer. D Women with a mutant allele of BRCA1will develop cancer. OCTOBER 2005 – 11: 27 A change within a single base pair in DNA is least likely to be observable if the change affects — A the production of a stop codon B* an unexpressed recessive trait C actions of a codominant allele D the expression of a sex-linked trait FALL 2005 – 11: 48 A change within a single base pair in DNA is least likely to be observable if the change affects — F the production of a stop codon G* an unexpressed recessive trait H actions of a codominant allele J the expression of a sex-linked trait FEBRUARY 2006 – 11: 5 The diagram above shows chromosomes in a cell undergoing cell division. If one of the chromosomes breaks during this process, which of the following will most likely happen? A* Mutation B Selection C Duplication D Segregation FEBRUARY 2006 – 11: 48 Which of the following is a change that could be passed on to an organism’s offspring? F* Damage to the DNA of gamete cells G Damage to skin cells from exposure to sunlight H Damage to DNA in the cytoplasm of cheek cells J Damage to hair pigment cells with permanent dyes APRIL 2006 – 10: 20 The diagram shows three generations of cells produced by a single cell through mitosis. In the process, a single mutation occurred at the point indicated. The mutation caused changes within a dominant allele. How many of the 15 cells contain the mutation? Record and bubble in your answer on the answer document. Answer: 7 APRIL 2006 – 10: 39 This illustration is an example of a normal DNA sequence. Which of the following represents a single base change in the sequence? Answer D APRIL 2006 – 11: 7 Which of these best explains how mutation can be beneficial to an organism? A* Phenotypic change may create an advantage over other organisms. B Recombined genetic material improves genotype stability. C Mitosis becomes a favored means of reproduction. D Deoxyribose sugars develop into additional nucleotides. APRIL 2006 – 11: 31 Sickle-cell anemia is a disorder resulting from a mutation that leads to the production of an abnormal protein. Which component of the DNA molecule provides instructions for the production of the protein? A The phosphate groups B The sugar molecules C* The sequence of nitrogen bases D The bonds that hold the sugars to the bases JULY 2006 – 11: 10 If one nucleotide is omitted or accidentally repeated in the process of DNA duplication, which of the following is most likely to occur? F Gene deletion G* Gene mutation H Gene insertion J Gene segregation JULY 2006 – 11: 32 A deletion of a DNA base from a gene affects an organism by — F causing future gametes to have additional chromosomes G* changing the sequence of amino acids in a protein H causing chromosome fragments to form long chains J changing the structure of ribose sugar in nucleic acids JULY 2006 – 11: 52 Which of the following is a change that could be passed on to an organism’s offspring? F* Damage to the DNA of gamete cells G Damage to skin cells from exposure to sunlight H Damage to DNA in the cytoplasm of cheek cells J Damage to hair pigment cells with permanent dyes