Health Protection: Infectious Diseases Executive Summary Control of infectious diseases is particularly important, as they have the possibility of affecting large numbers of people and can make then very ill. In England, infectious diseases account for £1 in every £10 spent in the NHS. Infectious diseases are also a major cause of days lost to the workforce. In the three year period 2007-2009, there were 90 deaths from infectious or parasitic diseases in North Somerset. The North Somerset mortality rate is lower than the England average but not significantly different. The mortality rate has fluctuated over the last 17 years. The number of deaths peaked in 2006 but has since fallen. 26% of these deaths occur in those aged under 75. With the exception of food poisoning, the number of notifiable diseases is low, although there were peaks of infection in 2009 for measles and in 2005 for mumps. Groups at high risk of infection include pregnant women; young children; over 65’s; those with pre-existing medical conditions; homeless; and substance misusers. Those in nurseries, residential and nursing homes are at increased risk of gastro-intestinal and other infectious diseases. Food Poisoning The most common notifiable disease in North Somerset is food poisoning, with 423 reported cases in 2009. Many cases of food poisoning are unreported. In 2009, the rate of food poisoning in North Somerset (202.2) was substantially higher than the national (134.2). This may reflect a higher level of reporting and demography. North Somerset Council’s Food and Safety Team investigates complaints of food and water borne infection and provides guidance to caterers. In 2010, 93% of establishments were broadly compliant with food hygiene standards locally compared to 92% nationally. Tuberculosis Although the rate of new cases of tuberculosis (TB) in North Somerset is low (5 per 100,000 compared to 15.4 nationally), it has been increasing broadly in line with the South West rates over the last 9 years. The PCT, Weston Area Health Trust and the local Health Protection Unit work jointly to ensure monitoring, control and treatment of TB in North Somerset. There is also provision to provide the BCG vaccination to babies at increased risk. Health Care Associated Infections Health Care Associated Infections (HCAI) are infections resulting from medical care or treatment in hospital (in- or out-patient), nursing homes, or even the patient's own home. Increased focus and vigilance have resulted in rates of Methicillin-resistant Staphylococcus aureus (MRSA) decreasing nationally and locally. Weston Areas Health Trust has seen a steady decline of cases since 2004. Between April 09 and March 10, there were 9 cases of MRSA and 95 of Clostridium Difficile in North Somerset patients attending any hospital. Local rates for PCT patients attending any hospital were similar to national rates. Blood Bourne Viruses. There has been a year on year increase in the number of Hepatitis C cases, but this may be due to improved laboratory reporting. The North Somerset Locally Enhanced Service for drug misusers specifies testing for blood borne viruses including HIV, Hepatitis A, B and C. Flu Immunisation is highly effective in preventing illness and hospital admissions from flu. Vaccination is available to the over 65’s and other high risk groups. In 2010/11 vaccination uptake in the over 65’s was 75.4% and 49.6% in the under 65’s at risk. In 2009/10, uptake locally was higher (75.5%) than the national average (72.4%) for the over 65’s and slightly lower (50.2%) for the under 65’s at risk (51.6% nationally). In 2009/10 50.2% of carers had the vaccine, above the national average of 42.3%. In the at risk disease groups, uptake was highest in those with diabetes and lowest in those with degenerative/neurological disease. There was a particularly low rate for those with chronic liver disease (37.7%). Uptake in pregnant women in 2010/11 was 48.3% compared with 37.7% nationally. There was a wide range of uptake by practice. Recommendations for consideration 1. Food Safety: Focus on businesses that are non-compliant with food hygiene; continue provision of level 2 food handling training; and provide targeted events in response to new legislation. 2. Tuberculosis: Ensure local service specification for treatment and management of TB conforms to recent NICE guidance. 3. Health Care Associated Infections: Maintain vigilance in infection control in health care establishments; increase control awareness and training in the community. 4. Blood Bourne Viruses: Improve surveillance of hepatitis B and C, particularly screening of pregnant women and monitoring of vaccination programmes for infants; CSDAT to look at surveillance of hepatitis with the drug and alcohol service. 5. Flu: Working with primary care to understand how vaccines are being delivered to different groups and reduce variations in uptake; improve communication with the public about flu vaccination. 6. Surveillance: Improve the timeliness and accuracy of infectious disease surveillance information Authors: Rosanne Sodzi, Public Health Specialist, North Somerset PCT (secondment) and Chris Gwenlan, Food Safety, North Somerset Council: Date: September 2011 Why is it important? Health protection covers a wide range of “threats” to our health. These include many diverse areas such as infectious diseases, “superbugs”, flooding, radiation, poisons and food safety. It is important that the health, safety and protection of the population from all external threats to health is rigorously maintained. Control of infectious diseases are particularly important, as they not only have the possibility of affecting large numbers of people, but often make people who contract them, very ill. In England, for example, infectious diseases account for £1 of every £10 spent on the NHS and are a major cause of days lost to the workforce.(source : HPA). Despite improvement in the general standards of living, broadened scope of vaccination programmes and refined used of antibiotics and other therapeutics, infectious diseases remain a major health threat. Mortality from infectious and parasitic disease Infectious diseases account for significant numbers of deaths, and rates vary over time. The data in table 1 shows mortality rates in North Somerset, and compares them with the surrounding areas and regional and national averages. Table 1: Mortality from infectious disease and parasitic disease in all ages: 2007-09 (pooled) Area No North Somerset Bristol South Gloucestershire BANES South West Region ENGLAND 90 202 88 71 1947 18,863 Directly Standardise Rate per 100,000 7.03 11.56 6.96 7.00 6.34 7.61 95% CI Lower 95% CI Upper 5.40 9.84 5.45 5.18 6.02 7.49 8.66 13.28 8.47 8.82 6.65 7.72 Source : The NHS Information Centre for health and social care There were 90 deaths due to infections or parasitic disease in North Somerset between 2007-09. It is likely that some of these could have been prevented with appropriate control of infection measures. This data shows that the rate of deaths due to infections in North Somerset does not differ significantly from the rates in the surrounding area, with the exception of Bristol where the rate is significantly higher. The rate is not significantly different from the national or regional rate. Graph 1: Mortality from infections and parasitic diseases (1993-2009) North Somerst : Mortality from Infections & Parasitic diseases 1993-2009 trend Rates per 100,000 Pop 14 12 10 8 Males Females 6 4 2 0 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Source : The NHS Information Centre for health and social care This trend data on rates of death from infections over the last 17 years, demonstrates that rates do fluctuate, with generally rates being higher in men than women. As can be seen from the chart below, the numbers of people dying in North Somerset varies substantially in different years. There was a significant increase in deaths in 2003-2008, which has only recently reduced again. Graph 2: Number of deaths from infectious and parasitic diseases (1993 – 2009) North Somerset : Number of deaths from infections and parasitic diseases (1993 -2009) 50 45 40 35 30 25 20 15 10 5 0 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Source : The NHS Information Centre for health and social care. Deaths from infectious disease affect those in younger age groups as well as the elderly. Nationally about 30% of deaths from infectious disease occur in the under 75s (see table 2 below). In North Somerset only 26% of deaths are in the under 75s, suggesting that locally, infectious diseases in the elderly are a significant concern. Table 2: Numbers of deaths from infectious diseases: Under 75s (2007-09) (Pooled) Area North Somerset Bristol South Glos BANES SW Region England Total No deaths 90 202 88 71 1947 18,863 of Deaths in under % of deaths in 75s under 75s 23 26% 61 30.2% 24 27.3% 17 23.9% 512 26.3% 5930 31.4% Source : The NHS Information Centre for health and social care There is therefore no room for complacency in the continued fight against infection. The challenge is that there are so many different areas which require constant attention. They range from ever-present threats such as gastrointestinal infections, through to bloodborne viruses such as hepatitis, sexually transmitted infections including chlamydia, syphilis and HIV/AIDS, and emerging infections such as meticillin-resistant Staphylococcus aureus (MRSA) to re-emerging infections such as tuberculosis. For many infections resistance to antibiotics continues to evolve. Nationally, the Health Protection Agency provide a specialist services to diagnose, monitor and evaluate the impact of infections. Locally, both within the NHS, and via the council, prompt action needs to be taken to limit the impact of outbreaks on the public. The needs of the population In a local area, the population face risks of many diverse threats each day, however, due partly to the work of those involved in health protection, these risks remain minimal most of the time. Health protection is carried out via the NHS and by specific directorates within the local council. Although the “threats” are diverse, the common theme of this type of work is to reduce the “threat” and address the “treat” if it arises. The work of health protection is about preparation, active prevention and rapid response when incidents arise. There is an important role in surveillance of disease and ensuring the spread of infection is minimised. High risk groups/inequalities All the above threats can affect the whole population at different times, however, there are particular vulnerable groups who are more prone to be affected by both infections and hazards, and any control systems need to take particular care to ensure their needs are met. These particular groups have particularly high needs: Pregnant women Infants and young children People over 65 People with pre-existing medical conditions Homeless people Drug and Alcohol misusers. Table 3: Notifications of Infectious Diseases (NOIDS) (2004-2009) Disease Whooping cough Viral hepatitis Disease Type 2004 3 2005 1 2006 3 2007 0 2008 4 2009 0 Hep A 0 1 0 0 0 0 4 20 1 4 119 0 13 9 4 10 7 2 1 6 5 417 7 41 0 1 10 0 7 4 3 7 7 0 0 0 7 473 3 76 0 0 4 0 6 4 2 2 1 1 0 2 10 449 0 2 0 0 3 5 0 0 0 0 0 0 0 0 1 10 9 1 1 1 1 0 0 0 0 1 403 423 0 1 1 0 7 1 0 4 Hep B Hep C Hep E 2 7 0 Measles 1 Mumps 40 Rubella 1 Tuberculosis 5 Pulmonary 4 Other forms 1 Meningitis 5 Meningoccal 1 Pneumococcal 2 Viral 2 Septicaemia 0 Shigella 6 Food 431 Poisoning Malaria 0 Dysentery Scarlet Fever Source : NOIDS Table 3 above show the notifiable diseases reported in North Somerset in the years 2004-9. The recording of diseases on this system is entirely reliant on doctors reporting cases to the HPA. This may account for some of the variation in rates of diseases recorded. Doctors in England and Wales have a statutory duty to notify a 'Proper Officer' of the Local Authority of suspected cases of certain infectious diseases. There are currently 31 notifiable diseases in the UK. For a full list see http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/NotificationsOfInfe ctiousDiseases/ListOfNotifiableDiseases/. The HPA publish weekly reports of all notifiable diseases. Most have very low incidence both locally or nationally, although there are some noted variations in some years e.g. measles and mumps. . The most common notifiable disease in food poisoning, and how this is addressed in North Somerset is described in the next section. Current Service Provision Health protection is managed nationally, regionally and locally. This section looks specifically at local level health protection issues for North Somerset. It includes sections on the following infections: Food Safety and Food Poisoning Tuberculosis Seasonal flu vaccination Healthcare associated infections Blood bourne viruses Food Safety and Food Poisoning Food Safety and Food Poisoning In North Somerset, in 2009, no cases of proven food borne outbreaks were reported to the Health Protection Agency, there were however, 432 notifications of food poisoning. It is considered that not all those suffering from food poisoning will contact their GP and therefore the number of official notifications is likely to be an underestimate of the total number of food poisoning cases within the district. Food poisoning impacts not only on the health of the individual but also on local health services and local economies due to lost working days. Through increasing the awareness of the potential sources of food poisoning and the hygiene standards within food businesses the public can make better choices about where to eat and how to prepare food hygienically thus and reduce their risk of food poisoning. Reporting suspected food poisoning is important even if the symptoms are not serious, as vulnerable groups ,ie the elderly, young or immuno-compromised , could become seriously ill if they eat contaminated food. Current service provision North Somerset Council‘s Food and Safety Team investigate complaints of food and water borne infectious diseases in North Somerset. This particularly applies to any infectious disease where the illness is caused by eating contaminated food or drink. They act on reports passed to them by GPs, members of the public, businesses, hospitals and other local authorities. Health practitioners are required to notify the Proper Officer for North Somerset Council via the Food and Safety Team of any suspected cases of food poisoning, which are then reported to the Health Protection Agency. Dependant on risk and provision of positive laboratory results individual cases and outbreaks are then subject to investigation. Table 4: No of food poisoning per 100,000 population for 2008 and 2009 for North Somerset, and surrounding areas & England. N Somerset England Bristol S Glos BANES 2008 195.7 125.7 150.2 113.2 153.6 2009 202.4 135.2 193.1 186.6 171.6 Source : HPA Local Profiles using NOIDS data North Somerset has the highest rate of food poisoning in the area, and the rate is substantially higher than the English average in both 2008 and 2009. This value does not mean that food safety standards are any poorer in North Somerset than elsewhere, it may just reflect a higher level of reporting and the make up of the population. Certain people are more likely to present to their GP with food poisoning than others such as mothers with small children and older people. Also those with confirmed food poisoning may have acquired the illness in another part of the country or abroad and not necessary from businesses in North Somerset. Food Safety In addition to the consumption of food at home, the public can be exposed to foodstuffs from a variety of sources such as restaurants, takeaways, school and work canteens, supermarkets, delicatessens, butchers and bakers. There is an increased risk of acquiring a food borne illness from food businesses that exhibit lower standards of food hygiene. In order to reduce the risk of food poisoning, North Somerset Council Food and Safety Officers take measures to ensure that food businesses operators who manufacture, prepare, cook and serve food to the public do so safely. Food safety officers carry out interventions to ensure that food is prepared in a safe and hygienic environment, and that those involved are suitably trained and have systems in place to support food safety. The food and safety team are able to provide advice and guidance on crosscontamination, temperature control, cleaning and disinfection, pest control, and food poisoning. They work in partnership with the Trading Standards team whose role is to ensure that food is labeled correctly, properly described and meets quality standards. Each food inspection will generate a rating for the quality of food hygiene witnessed by the officer, which is put onto a national database. Through increased awareness of the hygiene standards the public are empowered to make informed choices about which establishments they use and therefore reduce their risk of food poisoning. Table 5: Establishments broadly compliant with food hygiene standards N Somerset England Bristol S Glos BANES 2009 87.3% 92.1% 97% 99.3 97% 2010 93% 92.1% 97% 99.5 96.7% HPA Health Protection Profiles Current and Future Initiatives Future initiatives will primarily focus on those businesses that are deemed to be non compliant with food hygiene standards and a range of enforcement interventions will be used to drive up their compliance. Alternative enforcement initiatives include a comprehensive programme of food hygiene training for food handlers as well as sector specific events designed to support businesses in achieving compliance with their statutory duties. For example recent seminars have provided bespoke guidance for diverse groups as butchers and over 50% of North Somerset’s registered child minders. The intention is to extend this supportive approach to other client groups in future. Areas of Inequity in service provision Service provision is focused on achieving compliance with non-compliant businesses and our evidence is that non-compliance is not area specific. In North Somerset the gastro-enteritis outbreaks which were investigated in 2009 were due to viral infection such as, the noro-like virus. These tend to be more prevalent in semi-closed environments such as residential and nursing homes and amongst children who attend nurseries. This is because these establishments where people are in close proximity to one another provide ideal conditions for person-to-person spread. Noro-like viruses are highly contagious and as few as 10 viral particles may be sufficient to contaminate an individual. Information about food safety, North Somerset Council training courses, food poisoning and business compliance with food hygiene standards is available to the community via the North Somerset website: http://www.n-somerset.gov.uk/ Contact with the community and business is also achieved via our occassional magazine Food Safety News which is issued in response to matters of food concern. The preference is to provide this information portal via email and webbased contact in future. Established internal structures, such as exist in CYPS, will now be developed to disseminate information to client groups such as childminders. Food hygiene training is available via routine monthly courses or bespoke client group courses by request. Improvements in food hygiene have been noted following previous projects to facilitate food hygiene training for a number of ethnic minority food businesses including for Bengali, Turkish and Cantonese speakers. The outcome of these projects was to enable these groups to understand and comply with the legal requirements for documented procedures, which is a vital part of legal compliance. Achieving legal compliance vastly improves the food hygiene rating of the premises for which the outcomes are improved food hygiene and public choice. Recommendations 1. That food hygiene interventions focus on those businesses that are noncompliant with food hygiene requirements with the express intention of ensuring that a minimum of 50%` of these premises become broadly compliant within any 12 month period. 2. That the North Somerset Council officers continue to provide Level 2 food hygiene training for food businesses to ensure that food handlers are competent to handle, prepare and cook food hygienically. 3. That North Somerset Council officers provide targeted events for food businesses in response to emerging problems/new legislative requirements. References/data Food Safety Act: http://www.opsi.gov.uk/acts/acts1990/ukpga_19900016_en_1.htm European Communities Act: http://www.opsi.gov.uk/Acts/acts1972/ukpga_19720068_en_1 Food Standards Agency Code of Practice and Guidance: http://www.food.gov.uk/enforcement/enforcework/foodlawcop/copengland/copen gland North Somerset Council Food Safety Service Plan Food Standards Agency – Food Hygiene Rating Scheme http://ratings.food.gov.uk/ http://ratings.food.gov.uk/ Tuberculosis Tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis. It can cause disease in the lungs as well as other sites such as the lymph nodes and bones. Why is it important? TB, although curable with antibiotics, has re-emerged as a major Public Health problem and is the leading cause of death worldwide among curable infectious diseases. In England cases fell progressively until the mid-1980s but started to rise again in the early 1990s. What are the needs of the population? Case numbers in the UK are at their highest for nearly thirty years and now exceed 9,000 per year. Much of this rise affects disadvantaged communities including certain ethnic minority groups and those with social risk factors such as homelessness and drug/alcohol misuse. This concentration in particular sections of the community provides unequivocal evidence for a need to strengthen efforts to control the disease through a range of measures targeted at key risk groups and in particular urban areas. NICE are currently working on guidance on the management of TB in hard to reach groups. TB is a disease associated with poverty, specific groups of the population are at heightened risk: • • • • • • Close contacts of infectious cases Those that have lived in, travel to, or receive visitors from places where TB is still very common Those that live in ethnic minority communities originating from places where TB is very common Those with immune systems weakened by HIV infection or other medical problems The very young and the elderly as their immune systems are less robust Those with chronic poor health and malnutrition because of lifestyle problems such as homelessness, drug abuse or alcoholism. Tuberculosis in North Somerset Table 6: Average no of new cases (3 year rolling average) North Somerset 2001 – 03 5 2004 – 6 7 2007-9 10 Source : HPA Health Protection Profiles Table 7: Average incidence rate per 100,000 population North Somerset South West England 2001-3 3 4.4 13.1 2004-6 4 5.3 14.7 2007-9 5 5.6 15.4 Source : HPA Health Protection Profiles Table 8: Average incidence rates per 100,000 population in surrounding areas 2007/09 North Somerset Bristol S Glos BANES 2007-09 5 19 6 4 Source : HPA Health Protection Profiles Although rates in North Somerset are low, they are also increasing, and the rate is broadly in line with the South West rates over the last 9 years. A low indicator value should not mean that action is not needed as TB is preventable and any case of tuberculosis needs to be treated. Current Service Provision The PCT, Weston Area Health Trust and the local Health Protection Unit are working together to ensure that nationally approved systems for monitoring, control and treatment of tuberculosis are in place across North Somerset. There is a GP Referral pathway developed for suspected TB which is available at http://www.northsomersetpathways.co.uk/documents/other/clinical_policies_and_ guidelines/infection_control/tuberculosispolicy.pdf There is provision to provide BCGs to infants at risk of infection. Future Developments TB is curable if detected and treated early but the longterm nature and associated side effects of the antibiotic therapy can sometimes result in failure to complete treatment, leading to possible relapse and emergence of drug-resistant strains. The current six-month treatment regime was developed nearly half a century ago, and there is now an impetus (e.g. by the Global Alliance for TB DrugDevelopment) to modernise TB treatment. Antibiotics and inhibitors that are more effective and which could reduce treatment times are in phase II and phase III clinical trials. Other drugs are at the discovery phase or are in preclinical development. What works : the evidence base NICE has recently updated its guidance on the management and control of TB and this contains the most up to date guidance on treatment. NICE guidance : Clinical diagnosis and management of TB, and measures for its prevention and control. (March 2011) http://www.nice.org.uk/CG117 Recommendations To ensure that local service specification for treatment and management of TB conform to the recent updated NICE guidance. Health Care Associated Infections Why is it important? Health Care Associated Infections (HCAI) are infections resulting from medical care or treatment in hospital (in- or out-patient), nursing homes, or even the patient's own home. Previously known as 'hospital acquired infection' , the current term reflects the fact that a great deal of healthcare is now performed outside the hospital setting. Healthcare associated infection (HCAI) can affect any part of the body, including the urinary system (urinary tract infection), the lungs (puenmonia or respiratory tract infection), the skin, surgical wounds (surgical site infection), the digestive (gastrointestinal) system and even the bloodstream (bacteraemia). What type of infections are associated with healthcare? This chart shows a breakdown of healthcare associated infections by body system for the United Kingdom: Graph 3: Site of HCAI Source: Summary of Preliminary Results of the Third Prevalence Survey of Healthcare Associated Infections in Acute Hospitals 2006, England, Hospital Infection Society and Infection Control Nurses Association, 27 February 2007. There are a number of factors that can increase the risk of acquiring an infection, but high standards of infection control practice minimise the risk of occurrence. Often infections which occur in hospital are however contracted outside the hospital in the community. The HPA make the distinction of hospital and community acquired infection. An infection is not classed as hospital acquired unless it is evident after 48 hours in hospital. The Health Protection Agency assists infection control and the control of antibioctic resistance in the healthcare setting by monitoring infections with mandatory and voluntary surveillance schemes covering: methicillin-resistant Staphylococcus aureus (MRSA), Clostridium difficile infection (C. diff/CDI), glycopeptide-resistant enterococci (GRE), bacteraemia (blood stream infection), surgical site infections (of which some orthopaedic categories are mandatory) via the surgical site infection surveillance scheme (SSISS). Information on two of these conditions is presented here: MRSA and C Difficile which have presented particular challenges locally in recent years. MRSA Why is it important? Staphylococcus aureus is a bacterium that commonly colonises human skin and mucosa (e.g. inside the nose) without causing any problems. It can also cause disease, particularly if there is an opportunity for the bacteria to enter the body, for example through broken skin or a medical procedure. If the bacteria enter the body, illnesses which range from mild to life-threatening may then develop. These include skin and wound infections, infected escema, abcesses or joint infections, infections of the heart valves (endocarditis), pneumonia and bacteraemia (blood stream infection). Most strains of S. aureus are sensitive to the more commonly used antibiotics, and infections can be effectively treated. Some S. aureus bacteria are more resistant. Those resistant to the antibiotic meticillin are termed meticillin-resistant Staphylococcus aureus (MRSA) and often require different types of antibiotic to treat them. Both locally and nationally rates of MRSA have been decreasing, mainly due to increased vigilance within hospitals around infection control. This follows a period when rates of infection where very high. The renewed vigilence against these infections, meant that infection control became a top priority for Trust Boards, and Trusts had to mandatorily report rates. Below are the cases by quarter in Weston Area Health Trust as an example, showing a steady decline in numbers of cases since 2004. Graph 4: Number of cases of MRSA in Weston Hospital (2004 – 2010) Weston Area Health Trust : MRSA Cases by Quarter (Jan 2004 - Dec 2010) October to December 2010 July to September 2010 April to June 2010 January to March 2010 October to December 2009 July to September 2009 April to June 2009 January to March 2009 October to December 2008 July to September 2008 April to June 2008 January to March 2008 October to December 2007 July to September 2007 April to June 2007 January 2007 - March 2007 October 2006 - December 2006 July 2006 - September 2006 April 2006 - June 2006 January 2006 - March 2006 October 2005 - December 2005 July 2005 - September 2005 April 2005 - June 2005 January 2005 - March 2005 October 2004 - December 2004 July 2004 - September 2004 April 2004 - June 2004 January 2004 - March 2004 0 2 4 6 8 Source : HPA : HCAI mandatory surveillance Rates for North Somerset PCT are shown below, and these include cases not only from Weston Hospital, but any cases from other hospitals used by North Somerset residents. Table 9: Number of MRSA infections at Weston Area Health Trust (2007 – March 2011). PCT North Somerset – Rate per 100,000 population Totals cases 15 7.3 April 08 March 09 April 09 – Rate per March 2010 100,00 population Total cases 9 4.4 10 12 South Glos Bristol BANES 8 39 10 3.1 9.3 5.5 National rate 11 25 10 4.3 5.9 5.5 5.7 3.7 Source : HPA mandatory surveillance Although numbers of cases during the last three years has been decreasing, and this is seen in the reducing rates above, not only in North Somerset, but in the surrounding areas, rates are still above the national average. This may be due to the demographics of the local population, who are older than the national average. The rates are not adjusted to give a standardised rate which considers factors such as demographics or case mix. C. Difficile Like MRSA, rates of C Difficile have declined both locally and nationally. This is mainly due to increased vigilance within hospitals around infection control. Below are the cases by quarter in Weston Area Health Trust as an example, showing a steady decline in numbers of cases since 2007. Graph 5: Number of C. Difficile infections at Weston Area Health Trust (2007 – March 2011). Nos of C.Diff infections at Weston Area Health Trust in patients aged 2 and over by quarterApril 2007 to March 2011 January - March 2011 October - December 2010 July - September 2010 April - June 2010 January - March 2010 October - December 2009 July - September 2009 April - June 2009 January - March 2009 October - December 2008 July - September 2008 April - June 2008 January - March 2008 October - December 2007 July - September 2007 April - June 2007 0 10 20 30 40 50 60 70 80 90 Source : HPA HCAI Mandatory Surveillance Rates for North Somerset PCT are shown below, and these include cases not only from Weston Hospital, but any cases from other hospitals used by North Somerset residents. Again this shows much progress in reducing rates, with the overall rate in North Somerset in 09/10 the lowest in the area, and well below the national average, having been much higher, the previous year. Table 10: C. Difficile hospital acquired infections in North Somerset PCT patients (2008/09 – 2009/10). PCT North Somerset South Glos Bristol BANES – Rate per 100,000 population Totals cases 215 106.4 April 09 – Rate per March 2010 100,00 population Total cases 95 47.0 137 473 213 145 265 138 April 08 March 09 National rate 54.5 115.4 120.6 72.0 57.6 64.6 78.1 51.1 Source : HPA Mandatory Surveillance Recommendations To maintain the current vigilance in infection control within healthcare establishments to ensure rates of HCAI remain low. To increase infection control awareness and training in the community, including across primary care and social care services in North Somerset. Blood Bourne Viruses The most common serious viruses carried in people's bloodstreams are hepatitis B, hepatitis C and HIV. HIV is not covered here, see section on sexual health for information. Hepatitis B Hepatitis B is not very common in the UK: approximately one in 1,000 people are thought to have the virus. However, in some inner-city areas with a high percentage of people from parts of the world where the virus is common, as many as one in 50 pregnant women may be infected. Worldwide, the occurrence of hepatitis B is highest in sub-Saharan Africa, south-east Asia and the Pacific islands. Early symptoms of the hepatitis B virus are flu-like, and infection can lead to liver disease and liver cancer. The virus circulates in the blood and body fluids of infected people, and spreads by sexual contact, other close contact and the sharing of needles and razors. Babies with infected mothers can also become infected during birth. However, a vaccination is available. The vast majority of people who are infected with hepatitis B are able to fight off the virus and fully recover from the infection within a couple of months. However, most babies infected with hepatitis B have a poorer outlook, as their infection usually becomes chronic. It is important therefore locally that pregnant women are screened for Hepatitis B, and those with positive results are followed up, so that their babies can be vaccinated at birth, and complete a full course of vaccinations over the first year. 90% of infected babies will develop resistent Hepatitis B infections and be at risk of serious liver disease in later life. Hepatitis C People infected with hepatitis C virus often show no symptoms initially, but long term effects can include liver damage and cancer. The virus is transmitted by infected body fluids, and needle sharers are at particular risk. It is estimated that about 92% of cases are as a result of drug users sharing dirty needles. Babies can also be infected by their mothers during birth, though this is rare. No vaccine exists to prevent hepatitis C infection, but treatments are available that are effective in over 50% of cases. There has been a year on year increase in the number for Hepatitis C cases, but closer scrutiny of the data suggests that this may be due to improved reporting from the laboratory. The data does not necessarily represent newly acquired disease, it may be that the infection was acquired many years ago and has only now been diagnosed. The North Somerset Locally Enhanced Service for drug misusers includes ensuring that all problem drug users being treated under this service are tested and vaccinated for blood borne viruses, including HIV, Hepatitis A, B and C. Recommendations Improve the surveillance of Hepatitis B & C locally, particularly the screening of pregnant women, and the monitoring of vaccination programmes for infants. CSDAT to look at surveillance of Hepatitis within the drug and alcohol service. There is a specific problem obtaining hepatitis data as it is received from the HPA from laboratories, with often the PCT field not completed. It is therefore not possible to ascertain precise local figures. Taking laboratory figures (for example from Weston Hospital), as a proxi for PCT, is not accurate. There is also an issue about the laboratories releasing their data, as it is owned by them, not the HPA. Seasonal Flu Vaccination Programme Seasonal flu occurs every year, usually in the winter. It’s a highly infectious disease caused by a virus. Illnesses resembling influenza that occur in the summer are usually due to other viruses. Rates of seasonal flu vary each year, and within the year. Levels for 2010, for example, were generally lower than 2009. For example in the last week of November in 2009, the rate of primary care consultations for flu like illness in Avon was 38 per 100,000 population, a year later it was 6 per 100,000. The annual flu immunisation is the best protection against flu for people with underlying health problems that put them at risk of complications from influenza (flu), and for all those aged 65 and over. Why is it important? For most people under 65, who do not have underlying medical conditions, having flu, is unpleasant, but is not life-threatening. Most people need to stay in bed for a few days, and then recover. It is, however, much worse than a bad cold. Some people however are more susceptible to the effects of seasonal flu. For them it can increase the risk of developing more serious illnesses such as bronchitis and pneumonia, or can make existing conditions worse. In the worst cases, seasonal flu can result in a stay in hospital, or even death. For these groups, an annual vaccine against seasonal flu is recommended and available via GP practices. Immunisation is one of the most effective healthcare interventions available and flu vaccines are highly effective in preventing illness and hospital admissions among these groups of people. Increasing the uptake of flu vaccine among high risk groups should also contribute to easing winter pressure on primary care services and hospital admissions. High risk groups/inequalities Government policy is to recommend immunisation for people aged 65 years and over. The vaccination is recommended also for those who live in a residential or nursing homes, carers of an older or disabled person, or for women who are pregnant. Even if healthy, a free seasonal flu vaccination is available from GP practices if you are under 65 and have: • a heart problem • a chest complaint or breathing difficulties, including bronchitis or emphysema • a kidney disease • lowered immunity due to disease or treatment (such as steroid medication or cancer treatment) • a liver disease • had a stroke or a transient ischaemic attack (TIA) • diabetes • a neurological condition, for example multiple sclerosis (MS) or cerebral palsy • a problem with your spleen, for example sickle cell disease, or you have had your spleen removed. Current Service Provision The seasonal flu vaccination programme for the population of North Somerset is delivered through GP practices, and managed by NHS North Somerset. North Somerset Community Services carry out the vaccination programme to frontline health care workers and housebound patients. Information on uptake rates are given below. Table 11: Uptake rates for the seasonal flu vaccine in North Somerset: (2006/07 to 2010/11) Group 2006/07 People 76% aged 65 and over Under 65s 42% at risk 2007/08 75.6% 2008/09 77.2% 2009/10 75.5% 2010/11 75.4% 42.4% 46.2% 50.2% 49.6% Source : ImmForm web based reporting : DH/HPA Uptake rates are good for those 65 or over, the most recent figures for neighbouring areas and England are shown below. These are for 2009/10. North Somerset have uptake rates which are higher than both the regional and national average. For the under 65s at risk, rates are much lower, in all areas with only around 50% of those eligible, receiving the vaccination. The rate in North Somerset is slightly under the regional and national average. Table 12: Flu Vaccination Uptake (2009/10) PCT Uptake in over 65s North Somerset South Glos Bristol BANES South West SHA National rate 75.5% 78.2% 74.8% 74.0% 72.9% 72.4% Source : ImmForm web based reporting : DH/HPA Uptake in Under 65s at risk 50.2% 53.7% 50.5% 49.4% 51.8% 51.6% For the first time, in 2009/10 uptake rates for carers were available. In North Somerset, 50.2% of eligible carers had the vaccine. These are carers who look after an elderly or disabled person and are under 65 and not in an at risk group, and hence would not be covered by the main programme. This is well above the national average of 42.3%. The most recent figures available for carers show that there was a slight decrease in the carers rate of 48.8% in 2010/11. There are some differences in the uptake rates in the “at risk” groups. See rates for North Somerset and national rates below: Table 13: Seasonal Influenza vaccine uptake in those aged 6 months to under 65 years, at risk, by disease : NHS North Somerset and England (2009/10) At risk group Chronic heart disease Chronic respiratory disease Chronic kidney disease Chronic liver disease Diabetes Diabetes on medication Immuno-suppression Stroke/TIA Chronic degenerative/neurological disease (include MS) North Somerset 51.8% 50.2% England 56.5% 51.8% 49.7% 37.7% 66.5% 68.4% 55.7% 54.8% 41.2% 53.4% 42.1% 68.8% 71.9% 50.1% 59.0% 38.7% Source : ImmForm web based reporting : DH/HPA The pattern of uptake by disease is broadly similar to the England average, with the greatest uptake in people with Diabetes and the lowest rates in those with degenerative/neurological disease. Uptake rates by disease are mostly slightly lower in North Somerset than nationally. There is a particularly low rate for those with chronic liver disease. (37.7%). Another important at risk group is pregnant women. In 2010/11, there was an average uptake rate of 48.3%. Pregnant women at risk, had a slightly higher uptake rate of 56.1%. The overall national rate in 2010/11 for pregnant women was 37.7%, and hence North Somerset, have achieved a higher rate. Variation in uptake rates A concern is that when looking across North Somerset, there is a wide range in uptake rates by GP practice. The table below shows the range of uptake rates for each key group, showing the lowest uptake and the highest uptake rates. There is a particular issue with variation in rates for pregnant women and carers. Table 14: Uptake rates of the flu vaccination in 2010/11 Group Over 65s Clinical at risk Pregnant women Pregnant women at risk Carers North Somerset delivery range 67.1% – 82.3% 39.7% - 59.8% 7.1% - 74.1% 0 – 100% 9.1% - 100% % North Average 75.4% 49.6% 48.3% 56.1% 48.8% Somerset Source : NHS North Somerset Future planning The Chief Medical Officer sent a letter out in March 2011 detailing the seasonal flu vaccination uptake requirements for 2011/12. A suggested uptake delivery improvement trajectory, which will affect all General Practices within North Somerset over the coming years is as follows: 1. 2. 3. Reach or exceed 75% uptake for people aged 65 years or over. Reach or exceed 75% uptake for people under age 65 with clinical conditions. Reach or exceed 75% uptake for pregnant women. Given that North Somerset is already achieving the 75% uptake for the over 65s, the challenge here will be maintaining it, and improving rates in practices which are currently not achieving 75%. A suggested trajectory for uptake increases in clinical risk groups and pregnant women might be: Table 15: Suggested trajectory for increased uptake in clinical risk groups and pregnant women (2010/11 – 2013/14). Actual 2010/11 Under 65s at 49.6% risk Pregnant 48.3% woman Source : NHS North Somerset 2011/12 2012/13 2013/14 60% 70% 75% 60% 70% 75% These are very challenging targets, given current uptake rates in the under 65s and pregnant woman. Recommendations To have strong engagement with practice managers and understand on a monthly basis how GP practices are delivering the vaccinations to various groups and reduce variation in uptake between practices. To improve communications locally with the public over the availability and importance of the seasonal flu vaccination, particularly to high risk groups.