What I need to know about Mendelian Genetics Differentiate between heterozygous and homozygous genotypes by using letter symbols. 1. Indicate which is heterozygous by writing He and which is homozygous by writing Ho. Aa ____ LL ____ Nn ____ CC ____ MM ____ ee ____ ff ____ Gg ____ Pp ____ Ss ____ WW ____ ww ____ Tt ____ tt ____ aa ____ Zz ____ 2. Use the following terms to fill in the blanks: Homozygous Dominant, Homozygous Recessive, Heterozygous a. The genotype RR indicates a trait that is _______________. b. The genotype Tt indicates a trait that is ________________. c. The genotype ee indicates a trait that is _______________. 3. A student was describing the height, color, and type of plants that Mendel used in his experiment regarding genetics. Was the student describing the phenotypes or the genotypes of the plants? _________________________ 4. A tall is dominant to short plant. Write the phenotype for the following genotypes. a. TT__________ b. Tt ___________ c. tt___________ Explain the law of dominance. 5. If a trait is expressed, it is said to be dominant/recessive. (circle one) 6. If a trait is hidden or unexpressed it is said to be dominant/recessive. (circle one) Predict how genes sort and recombine to produce variations in offspring using Punnett squares. 7. In aliens, green in dominant over orange. Cross a homozygous dominant green alien with a heterozygous green alien. Phenotypic ratio: ________________ Genotypic ratio: ____________________ What percentage of the aliens born will be orange? ____________ 1 8. Pink polka dots are dominant to blue polka dots. Cross a recessive polka-dotted elephant with a heterozygous polka-dotted elephant. Phenotypic ratio: _______________ Genotypic ratio: ________________ What percentage of the elephant born will be heterozygous?__________ 9. A group of students wanted to determine how mouse fur color is passed from one generation to the next. The students mated mice for one year and recorded their results in the table. Parent Group Children of Each Parent Group Percent Black Percent White Both Black Mice 85 15 One Black Parent, One White Mouse 62 38 Both White Mice 0 100 Based on the data, is black or white fur color dominant? _____________________ Why? ________________________________________________________________________________ ________________________________________________________________________________ How can two black mice create a white mouse? ________________________________________________________________________________ Show the punnett square for proof: 10. Multiple Choice: A litter of puppies is 12 dogs. Six puppies are white and six puppies are brown. In puppies the allele for brown in dominant to the allele for white. What would the parent’s genotype be for this litter? (show the punnett square) A. rr x Rr B. Rr x Rr 2 Explain why recessive traits are more often expressed in the male. 11. The allele for muscular dystrophy is recessive. A female with the genotype, XdXd marries a man with the genotype XDY. What is the likelihood that their children will have muscular dystrophy? 12. Hemophilia is a sex linked trait. A female carrier marries a man that is does not have hemophilia. What percentage of their offspring will inherit the trait for hemophilia? ____________ What percentage of their offspring will NOT inherit the gene for hemophilia? __________ What percentage of the males will inherit the trait for hemophilia? _____________ What percentage of the females will be carriers?_____________ 13. Fill in the blanks with the following terms: Allele, recessive, X, males, hemophilia, carrier, female, affected, X chromosome, X AXa, XaY Sex-linked traits are found on the _____________________________________. Typically they are most often expressed in ________ because they have only one ___ chromosome. A ________ can be affected; however, it is rare. Some of the time, a female can be a __________, which means that she has one ________ for the trait, but does not show it. A male cannot be a carrier and can only be normal or __________. Two conditions that are sex linked are _______________ and colorblindness. The genotype of a female carrier would be _______. The genotype of a male who is affected would look like this _____. Illustrate and explain how expressed traits are passed from parent to offspring by analyzing pedigree charts. 14. What does a pedigree chart show? ______________________________________________ ____________________________________________ 15. The pedigree to the right shows a (sex linked trait/normal trait). (circle one) Explain how you know. ____________________________________________ ____________________________________________ 3 16. Shade in all the heterozygous individuals in this pedigree. 17. Using the pedigrees, draw symbols for the meanings listed: Symbol Meaning Affected Female Normal Male Carrier Female Affected Male Explain what the roman numerals represent. ________________________________________________________________________________ _______________________________________________________________________________ Explain how the marriage of two people is shown. ________________________________________________________________________________ ________________________________________________________________________________ Explain how offspring are shown. ________________________________________________________________________________ _______________________________________________________________________________ The pedigree below shows the occurrence of red-green colorblindness in four generations of a family. Use the information in the pedigree to answer the following questions: 18. How many individuals have red-green colorblindness in the four generations shown in the pedigree? a. 3 b. 4 c. 7 d. 12 19. In generation IV, individual 5 married someone who is not a carrier of redgreen colorblindness. If they have a female child, what is the chance that she will be born with red-green colorblindness? a. 0% b. 25% c. 50% d. 100% 20. How many females are carriers for red-green colorblindness? ________ 21. How do you know that this pedigree is a sex-linked trait? ______________________________________________________________________________ ______________________________________________________________________________ 4