BIO 141: Anatomy & Physiology I Faculty Information Siabhon M. Harris, Ph.D. 120 Campus Drive Portsmouth, VA 23701 Office: Building B, Rm B119-O Phone: (757) 822-2316, (757) 504-4246 Fax: (757) 447-3488 Email: smharris@tcc.edu Required Course Material Textbook: Human Anatomy and Physiology, Eighth Ed., Elaine N. Marieb and Katja Hoehn. Bundled package (ISBN 9780321732187) includes: Textbook, Lab Manual (9th edition), a Brief Atlas, and the Course Compass/My A&P Access. Mastering A&P Access: Access to Mastering A&P is required for BIO141. If you purchased your bundled package from the TCC Portsmouth Bookstore, an access kit will be included with the purchase of your new textbook. If you do not have an access code, you will need to purchase access online at http://www.masteringaandp.com/site/register/new-students.html (Priced at approximately $50.60 USD) BIO141 Course Description Biology 141 is an instructional and investigative program designed to provide students with a basic foundation in the structure and function of the human body. BIO141 integrates anatomy and physiology of cells, tissues, organs and organ systems in the human body. This course also integrates topics in chemistry, physics and pathology. The overall objectives of this course extend beyond the specific content of the text and laboratory. Lecture 3 hours. Laboratory 3 hours. Totals 6 hours per week. Please be aware that this course is both demanding and rigorous. College level reading and writing skills are absolutely necessary for students taking this course. Students must be self-motivated and self-disciplined, possess good time management skills, and have the necessary computer skills and equipment to successfully complete the required work in the course. Course Syllabus Spring 2011 Inside this Syllabus: TOPIC PG Faculty Info Course Material Course Description Course Topics Course Approach Blackboard Email Course Feedback Grading Criteria Makeup Exam Course Policies Classroom Policy Student Success Additional Institutional Policy Attendance Policy Handbook Policy Course Schedule Learning Outcomes 1 1 1 2 2 2 3 5 7 9 Required Prerequisites or Corequisites No prerequisite or corequisite is required for BIO141.However, a strong background in high school biology and/or introductory level biology course (such as BIO100 or BIO101) is recommended. BIO141 COURSE TOPICS Students will cover the following topics in this course 1. Major themes of Anatomy and Physiology: Orientation to the Human Body 2. General and Organic Chemistry 3. Cellular Anatomy and Physiology 4. Histology 5. Integumentary System 6. Skeletal System 7. Muscular System 8. Nervous System 9. Endocrine System Click each topic above to see the course learning outcomes for each topic COURSE APPROACH Blackboard TCC Main Menu Login Click on the Course Shell. Use this to download lecture outlines, take quizzes and obtain other course materials. Download materials before the class that it is needed. Email Each student MUST have an active VCCS e-mail account. This will be your login for Blackboard, as well as the e-mail address that is used for any communication from your instructor. E-mail may be sent from student-to-student, or studentto-instructor using the e-mail feature in Blackboard’s Communication area. You may also send e-mail to the entire class in this section – but these messages should contain information that the entire class would benefit from reading, and follow proper netiquette guidelines (no flaming, no commercial use, etc.). Course Feedback Students who e-mail me Monday – Thursday will ordinarily receive a response within 48 hours. Students who e-mail me Friday – Sunday may expect a response by 5 pm on Monday. All projects that are completed and received by the due date will be graded and returned to the student in 7 to 14 days. NOTE: Students are expected to retain an electronic copy of all work submitted. If transmission of the work fails, students are expected to “resend” the document under directions of the instructor. Projects will be submitted in Blackboard either through a discussion thread or via the assignment feature. Students are expected to verify their own Blackboard responses by returning to the appropriate place in Blackboard after the work has been posted. GRADING CRITERIA Grading Criteria Each student must be registered for BOTH the lecture and the lab at the Portsmouth campus. A single letter grade is given for Biology 141. However, the grade has two weighted components. The grading scale is as such: A 100 – 90 B 89 - 80 C 79 - 70 D 69 - 60 F Below 60 Grade Calculations The final grade will be calculated using the following percentages: Percent of Final Grade Graded Task Lecture Examinations (5) Comment: You will be given 50 minutes to take each lecture exam. Exams will include all information given in a specific unit. The first exam is worth 5%, whereas exams 2-5 are worth 10%. On occasion, a percentage (25%) of an individual lecture exam grade will require completion of a case study, small paper or similar task. Final Examination (1) 45% 10% Comment: The final exam will be CUMULATIVE and include ALL information covered in the course. Quizzes (Varied) Comment: You will have at least one online quiz a chapter, as well as the possibility of pop-quizzes throughout the semester. There are NO MAKE UP quizzes regardless of the reason; however the lowest ONE quiz grades will be dropped to allow for absences and other circumstances 5% Laboratory Section (1) Comment: Your lab grade will come from your lab instructor. You are required to pass the laboratory portion in order to pass the 141 course. A failing grade in lab (less than 60%) will automatically result in a failing grade (F ) for the entire course – no exceptions! 40% Mastering A&P Study Sessions – Extra Credit Comment: For each chapter, you will have Mastering A&P study sessions available to complete online. These assignments typically require anywhere from 50-90 minutes to complete. The final grade average of these assignments are considered extra credit and can add up to 2% to your final 141 grade. While 2% may not seem like a lot, it can make a difference between a letter grade. All study sessions must be completed by the start of the final exam for credit. Total 2% 100% Final grades are made available to each student within the Student Information System (SIS) now web delivered via MyTCC or SIS. Based on the progression of the course, the grade distribution for each assignment may change. However, if changes are made, students will be notified ahead of time and in writing. Make-Up Exam Policy: You may make up only ONE lecture exam during the semester, if the following conditions are satisfied: 1. The reason for your absence must be SERIOUS (personal illness, illness of a child, death in the family, etc.) with documentation 2. The instructor must be contacted by e-mail (smharris@tcc.edu) BEFORE OR THE DAY OF THE ABSENCE. Failure to contact your instructor will result in you not being able to make up the exam. 3. The exam missed must be made up within one week of the missed exam in the testing center. More than one absence on any other exam day will result in you receiving a zero for that exam. Failure to take one or more lecture tests or laboratory practicals at the scheduled time will be considered unsatisfactory attendance unless prior arrangements have been made with the instructor COURSE POLICIES Classroom Policies 1) This course is highly dependent on blackboard and online supplementation. Students must complete required course work on time and in the appropriate sequence of learning. 2) Students must login in to blackboard at least every other day to check the course updates and announcements, take quizzes, submit written assignments, obtain lecture material, etc. It is the students responsible to keep up with and adhere to due dates posts on Blackboards 3) Students must maintain a working TCC email address and check it every routinely. 4) Ask questions about the course in Blackboard A&P Café Corner Discussion board, rather than email. This board is designed for questions, which others may also have, that may be answered for all class members to see. This saves the instructor from having to answer the same question over and over again. This board is checked every Friday. 5) Email the instructor about any PRIVATE conflicts or questions you may have. Please expect a reply email within 48 hours. If you have not heard from the instructor in 48hrs, please re-send the email. 6) Grades are typically submitted within 7-14 days and posted on the Blackboard gradebook. Submission of Late Assignments In general, late work is NOT accepted regardless of the situation. You are given ample time to complete and submit assignments; therefore, you are expected to submit these assignments prior to the due date – do not wait until the last minute. All assignments should be submitted in person, via email or, if available, through blackboard by the appropriate due date. Students who are unable to submit assignments by the due date, due to technical difficulties or an acceptable excuse (i.e., must be SERIOUS reason (personal illness, illness of a child, death in the family, etc.) with documentation), you must contact the instructor within 24 hours of the due date. Student Success Resources The best strategy for success in BIO 141 is to: A) Design your study time based on the weekly learning units. Studying is a requirement in this course. B) Read the textbook, especially for topics that are unclear in the powerpoint lectures C) Check in on Blackboard Updates and News at least every other day to stay up-to-date on posted announcements and lecture material D) Ensure you pay close attention to and meet all deadlines for quizzes, tests, and assignments E) Form study groups and meet at least once a week The following resources are available to TCC students. See the Student Handbook or visit http://www.tcc.edu/forms/handbook/ for more information about student services and locations. Learning Resource Centers Each campus houses a library and media resources in a Learning Resources Center (LRC). A separate slide and print library is located at the Visual Arts Center. The Learning Resources Centers contain research materials in both print and electronic format to support the courses, curricula, and mission of the college. Library materials include books, newspapers, magazines, journals and an extensive collection of indexes, abstracts and full text databases. Media resources include videotapes, audiotapes, films, CD-ROM/DVD, computer files, and other audiovisual materials. Visit this site for more information: www.tcc.edu/lrc/ Tutorial Services Tutors are available at no charge to the registered TCC students in the Learning Lab. Please contact the Tutoring Center at the Portsmouth Campus for more information. The Learning Assistance Center provides students with the opportunity to receive assistance in biology. This not only includes tutoring services, but the studying techniques as well. The center is located in Building A, Room 110. Please visit their website for additional information and hours: http://www.tcc.edu/academics/ divisions/lms/lac.htm. Supplemental Instructor: Check blackboard for information of the A&P supplemental instructor Academic Support Services Each campus provides various kinds of academic assistance. One-on-one tutoring, math and computer labs, and other forms of individual and group assistance may be available. Students can also find free help for writing, from short questions about commas and comma splices to a comprehensive review of research papers in progress, in the Writing Centers. Online Help Desk Visit the following Distance Learning Resources for Students website for information about computer skills, technical support, library services for online students, and much more: http://www.tcc.edu/students/dtls/ Important Websites College Website: www.tcc.edu Blackboard and Student E-mail: https://tcc.my.vccs.edu/jsp/home.jsp Student Handbook: http://www.tcc.edu/forms/handbook/ TCC Catalog: http://www.tcc.edu/forms/catalog/ Class Schedule: http://www.tcc.edu/schedule/ (or log-in to SIS for current course offerings) Academic Calendar: http://www.tcc.edu/students/calendar/academic/index.htm Distance Learning Resources: http://www.tcc.edu/students/dtls/ Additional Course Policies 1. Statement on Classroom Behavior: TCC is committed to maintaining a social and physical environment conducive to carrying out its education mission. Therefore, all students are expected to demonstrate standards for civility. Be moderate in speaking. Loud, obscene, argumentative, or threatening speech is disruptive to teaching and learning and is offensive to others. It has no place in an academic setting. Resolve any disagreements in a positive, non-combative manner. Request the assistance of college authorities if needed. Show respect for the comfort of others in an educational setting by observing acceptable standards for personal cleanliness and dress.” 2. Electronic Devices Policy: Cell phones, pagers, and other communication devices are prohibited from use in classrooms, laboratories, and libraries, unless authorized by the appropriate faculty or staff. Although soundless communication devices such as cell phones and pagers are permissible in classrooms, college offices, and/or meeting rooms, they must not be answered during class. 3. Disposition of Classes for Emergency Shutdown of the College: In the event of an emergency shutdown of the college, the president and her executive staff may elect to conclude the term in session if eighty-five percent or more of that term has been completed. If the term in session is concluded, faculty shall compute final grades of students based on coursework completed at that point. INSTITUTIONAL POLICIES Attendance Policy All students are expected to be present and on time to all scheduled class meetings. Instructors are not required to admit a student who arrives late to the classroom. A student who adds a class or registers after the first day of classes is counted absent from all class meetings missed. If a student is absent more than 20 percent of scheduled instructional time, attendance may be defined as unsatisfactory. This calculation includes absences occurring during the add/drop period. See also the Withdrawal Policy in this syllabus for more information. Per the college’s attendance policy, faculty has the right to develop a more stringent policy as well. In the event of your absence from class, the student is responsible for determining and making up all work missed when and if missed work is allowed to be made up. When your absences in a course equal the number of weekly class meetings, your permanence in the course may be in jeopardy. Unsatisfactory attendance in the course may be defined as absences in excess of twenty percent of scheduled instructional time in either lecture or laboratory or failure to take one or more major exams or laboratory practicals. Please remember that only registered students are allowed in the classroom. This means that family, friends, or children are not be taken to lecture. Student Handbook Policies Students are responsible for being aware of the policies, procedures, and student responsibilities contained within the current edition of the TCC Catalog and Student Handbook. Students should familiarize themselves with the college's policies regarding misconduct and inclement weather found in the Student Handbook. Withdrawal Policy Students who wish to withdraw without academic penalty should contact a counselor to determine the appropriate procedure. Withdrawals through completion of 60 percent of a session will result in a W grade. After 60 percent of a session is completed, a withdrawal will result in a grade of F in a credit course or a grade of U in a developmental course, except under mitigating circumstances that must be documented by the instructor and approved by the academic dean. Dynamic session classes have unique refund and withdrawal dates. Contact a campus Enrollment Services Office for more information, or visit http://www.tcc.edu/students/calendar/academic/Dynamic.htm. A student who drops after the last day to withdraw does not receive a "W." He/she receives an "F," in which case there is both an academic and financial penalty. A student who withdraws by the deadline faces a financial penalty, but not an academic penalty. January 25 March 23 Deadline to drop for tuition refund Deadline to withdraw without academic penalty and to receive a grade of W for the course It is the responsibility of the STUDENT, not the instructor, to withdraw themselves from the class by the withdrawal date. A student may be withdrawn from the course by the instructor “when the instructor determines the absences constitute unsatisfactory attendance.” Unsatisfactory attendance is defined as absences more than 15 % of lecture and lab sessions. Instructors cannot withdraw a student after the withdraw date except where there are mitigating circumstances AND if the student is making satisfactory progress in the course. Please see your student handbook for a complete explanation. Academic Integrity TCC will expect students to demonstrate personal and academic integrity, to be open to new ideas, and to share in a community where individuals from diverse backgrounds and cultures help one another grow intellectually, socially, and personally. TCC expects students to achieve, not just to get by. And while many caring and talented faculty and staff are here to help, students must take responsibility for their own learning. Students should strive for a high level of academic performance and to be responsible, contributing citizens within the college and in outside communities. Above all, TCC wants students to develop a love of learning that will last a lifetime, along with a life-long interest in maintaining emotional and physical wellness. Statement on Plagiarism and Academic Misconduct The paragraphs below come from the Student Handbook and are TCC’s policy on plagiarism and academic misconduct. Including the following statement verbatim: Academic misconduct includes, but is not limited to, the following actions: cheating on an examination or quiz—either giving or receiving information; copying information from another person for graded assignments; using unauthorized materials during tests; collaboration during examinations; buying, selling or stealing examinations; arranging a substitute for oneself during examinations; substituting for another person, or arranging such a substitution; plagiarism—the intentional or accidental presentation of another’s words or ideas; collusion with another person or persons in submitting work for credit in class or lab, unless such collaboration is approved in advance by the instructor. Faculty members who have reliable evidence of academic misconduct will (1) investigate the matter, and (2) review the facts of the matter and the proposed penalty with the appropriate academic dean. They may then take one or more of the following actions: Require the work to be accomplished again Give no credit for the test, paper, or exercise Assign a grade of F, U, or W for the course Refer the matter to the campus Dean for Student Services or designee for possible disciplinary sanction through the college’s disciplinary procedure If the faculty member chooses to refer the matter to the campus Dean for Student Services or designee for disposition, the Plenary Disciplinary Procedure shall be followed, and the student’s dismissal from the college is a possibility. Plagiarism is a serious offense (cheating), whether it is intentional or unintentional. It is your responsibility to be aware of what plagiarism is and how to avoid plagiarism. It is considered academic misconduct (defined in the Student Handbook) and can result in failure of the course or dismissal from the school. You will have an assignment on Plagiarism this semester. Please refer to the syllabus schedule and Blackboard assignment section. Disability Services Students who have documented, diagnosed disabilities, and who need special accommodations for tests, etc., are advised to see the Disabilities Services staff in Student Services so that the instructor may be notified of what accommodations are appropriate in each case. Requests for accommodations should be made to the designated campus disability services counselor at least 45 days before classes begin. Documentation must be provided to support the need for accommodations. For assistance with disabilities, contact the campus Disabilities Counselor/Provider or the Coordinator of Learning Disabilities Services: call 822-1213, visit Student Services/Development, or visit the Disability Services webpage at http://www.tcc.edu/students/specialized/disabilityservices/index.htm Policies and Procedures All students should refer to the 2010-2011 TCC Catalog and 2010/2011 Student Handbook (or most current edition) for college polices, regulations, student conduct, and other student affairs. Emergency Procedures In the event of a bomb threat, tornado, or fire, students and staff may be asked to evacuate the building or move to a secure location within the building. Evacuation routes for movement to an external location or to a shelter within the building are posted at the front of the room. Students should review the maps and make sure that the exit route and assembly location for the building are clearly understood. If assistance is required during an evacuation, please let the instructor know at the end of the first class. Tidewater Community College uses TCC Alerts to immediately contact and inform faculty, staff and students of a major crisis or emergency. TCC Alerts delivers important emergency alerts, notifications, and updates via: Email account (work, home, other) Cell phone Pager Smartphone/PDA (BlackBerry, Treo & other handhelds) When an incident or emergency occurs, authorized senders will be instantly notified via TCC Alerts. TCC Alerts is a personal connection to real-time updates, instructions on where to go, what to do, or what not to do, who to contact, and other important information. New users may also register by sending a text message to 411911, keyword: TIDEWATER. In the event of an emergency that requires the college to shut down, if 85 percent of a 16-, 10-, or 8-week term has been completed, students will receive the grade earned during that period of instruction. If an emergency shutdown of the college occurs, students should contact their instructors using Blackboard for directions. This is in accordance with TCC’s Academic Continuity of Operations Plan. However, sciences will require that 100% of labs be finished before acquiring a grade for the course. Lab instructors will advise a new schedule for students if needed. COURSE SCHEDULE Students will complete the following assignments by the specified due date. Specific requirements for each assignment are spelled out in the assignment section of Blackboard. Note: The following schedule is intended to provide a relative framework for course topics and assignments. Additionally, course adjustments may be based upon on-going class progress assessments. Additions and deletions will occur at the instructor's discretion. LECTURE SCHEDULE Week Dates 1 1/09 – 1/15 2 1/16 – 1/22 Lecture Topics - Chapter Class and Syllabus Review Introduction – 1 Basic Chemistry – 2 Biochemistry – 2 MLK, Jr. Day – 1/16 – No Class 3 1/23 – 1/29 Exam 1 (Chpts 1-2) Cell Membranes/ Transport – 3 4 1/30 – 2/5 Organelles and Central Dogma – 3 Epithelial – 4 5 2/6 – 2/12 Connective tissue – 4 Integumentary System – 5 6 2/13 – 2/19 Exam 2 (Chpts 3-4) Integumentary System – 5 Bone structure and physiology – 6 7 2/20 – 2/26 Bone growth and repair - 6 8 2/27 – 3/4 Muscular Structure – 9 SPRING BREAK 9 3/12 – 3/18 Muscular Metabolism– 9 REVIEW 10 3/19 – 3/25 Exam 3 (Chpts 5, 6, 9) Neurophysiology I – 11 11 3/26 – 4/1 Neurophysiology I – 11 CNS: Brain – 12 12 4/2 – 4/8 CNS: Brain – 12 13 4/9 – 4/15 Exam 4 (Chpts 11 - 12) Peripheral Nervous System – 13 14 4/16 – 4/22 Peripheral Nervous System – 13 Autonomic Nervous System - 14 15 4/23 – 4/29 Autonomic Nervous System - 14 16 4/30 Exam Week 5/1 – 5/7 Senses – 15 (if time available)/ Review Exam 5 (Chpts 13-15) COMPREHENISIVE FINAL EXAM http://www.tcc.edu/students/schedules/exams/spring.ht m The above course schedule may change due to the progression of the course at the discretion of the instructor. Learning Outcomes for Each Course Topic After the completion of this course, students will be able to: 1. Major Themes of Anatomy and Physiology: Orientation to the Human Body 1.1 Define anatomy and physiology and their subdivisions 1.2 Explain the concept of complementarity of structure and function and give examples 1.3 List and describe, in order from the simplest to most complex, the levels of organization in the human body and give an example of each 1.4 List the 11 organ systems of the human body, identify their principal organs, and describe the functions of each 1.5 List and describe the requirements for life, and give examples of each that are relevant to human survival 1.6 Define homeostasis and provide specific examples of how the human body maintains homeostasis in spite of changes in the internal and external environment 1.7 Compare positive and negative feedback mechanisms and identify examples of each 1.8 Describe the relationship between homeostatic imbalance and disease 1.9 Describe an individual in the correct anatomical position 1.10 Define the major body directions, regions, and planes or section. 1.11 Describe the position of one bodily structure relative to another using the proper terms 1.12 Name and locate the major body cavities and their subdivisions, and identify the major organs of each 1.13 Name the serous membranes and describe their common structure and function 1.14 Name the four quadrants and nine regions of the abdominopelvic cavity and identify the major organs of each 2. General and Organic Chemistry 2.1 Define energy, matter, and mass. 2.2 List the major forms of energy, and discuss potential and kinetic energy. 2.3 Define element and list the common elements of the human body, using atomic symbols. 2.4 Define atom and describe the structure of an atom by explaining the relative position, mass, and charge of protons, neutrons, and electrons. 2.5. Define atomic number, atomic mass, atomic weight, isotope, electron cloud, orbital, valence electron, octet rule, and ion. 2.6. Discuss the role of electrons in atomic bonding and be able to predict what kinds of chemical bonds individual atoms will make with each other. 2.7. Compare and contrast ionic, covalent (nonpolar and polar), and hydrogen bonds. 2.8. Define molecule, and distinguish between compounds and mixtures. 2.9. Compare and contrast the properties of nonpolar and polar compounds. 2.10. Identify the reactants and products in a chemical reaction. 2.11. Define the three major types of chemical reactions synthesis, decompensation, and exchange - and give examples of each. 2.12. Describe oxidation-reduction reactions and give examples. 2.13. List factors that affect the rate of chemical reactions, and discuss the role of enzymes, cofactors, and coenzymes. 2.14. List and discuss chemical properties of water, including heat capacity, heat of vaporization, solvent properties, and reactivity. 2.15. Explain the importance of water and salts to homeostasis. 2.16. Differentiate between solute, solvent, solution, colloid, suspension and emulsion. 2.17. Define acids, bases, salts, buffers, and pH and give significant examples. 2.18. Describe the pH scale. 2.19. Describe the role that weak acids and weak bases play in maintaining normal pH balance. 2.20. Distinguish between organic and inorganic molecules. 2.21. List the four major types of organic compounds carbohydrates, lipids, proteins, and nucleic acids - and describe the monomers, polymers, and functions of each. 2.22. Explain the role of dehydration synthesis and hydrolysis reactions in the formation and breakdown of organic molecules, and give examples for each category of organic molecule. 2.23. Describe the four levels of protein structure and explain the importance of structure and function. 2.24. Compare and contrast the structure and function of DNA and RNA. 2.25. Describe ATP and ADP and discuss their roles in cell metabolism. 3. Cellular Anatomy and Physiology 3.1. Define cell and list the tenets of the cell theory. 3.2. Describe the Fluid Mosaic Model of the plasma membrane, and be able to draw and label the major parts. 3.3. Compare the structure and function of tight junctions, desmosomes, and gap junctions. 3.4. Describe the role of the glycocalyx and extracellular matrix in a cell's interaction with its environment and other cells. 3.5. List several roles of membrane receptors and membrane channels. 3.6. List the major types of membrane transport. 3.7. Relate the structure of the plasma membrane to transport mechanisms. 3.8. Compare active and passive transport mechanisms with respect to energy source, substances transported, and direction of transport. 3.9. Define membrane potential and explain how the resting membrane potential is maintained. 3.10. Describe the composition of cytosol and list types of inclusions. 3.11. Identify all cell organelles and describe the location, structure, and function of each. 3.12. Name and describe the structural elements of the cytoskeleton. 3.13. Describe the cell cycle and the major events occurring during each stage of interphase and mitosis. 3.14. Identify the stages of mitosis on a model and by microscopy. 3.15. Describe the process of DNA replication. 3.16. Describe the structure and function of genes and define genetic code. 3.17. Define transcription and translation. 3.18. Discuss the process of protein synthesis, starting with a DNA template and describing the specific roles of DNA, mRNA, rRNA, and tRNA, triplets, codons, and anticodons. 3.19. Explain the relationship of cancer to the cell cycle and describe how cancer may arise. 3.20. Define metabolism, including anabolism and catabolism. 3.21. Compare and contrast aerobic and anaerobic metabolism. 3.22. Describe the metabolic pathway for carbohydrates, including glycolysis, formation of acetyl CoA, Kreb's cycle (citric acid cycle), and electron transport chain; include specific intracellular locations and ATP yield for each process. 3.23. Describe the metabolic pathway for lipids. 3.24. Describe the metabolic pathway for proteins. 3.25. Discuss the role of adipose tissue, the liver, and skeletal muscle in metabolism. 4. Histology 4.1. List the steps involved in preparing tissue for viewing with a microscope. 4.2. Identify the parts of, and demonstrate the proper use and care of a microscope. 4.3. List the four primary types of tissue and compare and contrast the general features and functions of each category. 4.4. Classify the different types of epithelial tissue, identify each by microscopy, including any special features, and name a location and function of each specific type. 4.5. Define gland. Differentiate between unicellular and multicellular glands and endocrine and exocrine glands. 4.6. Describe how multicellular glands are classified structurally and functionally. 4.7. Classify the different types of connective tissues, identify each by microscopy, including any special features, and name a location and function for each specific type. 4.8 List common characteristics of connective tissues and identify the specific types of fibers, cells, and distinguishing features within each specific subtype. 4.9. Classify the different types of muscle tissue, identify each by microscopy, including any special features, and name a location and function for each type. 4.10. Identify nerve tissue by microscopy, and describe the characteristics of nerve tissue, including general functions of neurons and neuroglia. 4.11. Describe the structure, function and location of mucous, serous, cutaneous, and synovial membranes. 4.12. Describe the major steps of tissue repair. 4.13. List the embryonic origin of each of the major types of tissue. 5. Integumentary System 5.1. List and describe at least five functions of the skin and hypodermis. 5.2. Identify (on diagrams, models and by microscopy) and describe the epidermis, its tissue type, specific cells, layers, and functions of each. 5.3. Identify (on diagrams, models, and by microscopy) and describe the dermis, its tissue type, specific cells, layers, and functions of each. 5.4. Identify (on diagrams, models, and by microscopy) the hypodermis, its tissue type, cells, and functions. 5.5. List and describe the major pigments responsible for skin color and discuss how changes in skin color may be indicative of certain diseases. 5.6. Define and identify melanocytes, keratinocytes, Langerhans cells, Pacinian corpuscles, Meissner’s corpuscle, Merkel’s discs, Ruffinian corpuscles, and hair follicle receptors. 5.7. Identify and describe the location, structure, and function of eccrine and apocrine sweat glands, sebaceous glands, hair, and nails. 5.8. List the three major types of skin cancer, the major causes, and their characteristics. Describe the ABCDE rule for detection of melanoma. 5.9. Describe how to classify burns and why serious burns can be life threatening. Describe the rule of nines for approximation of fluids and classification of critical burns in adults. 6. Skeletal System 6.1. List and describe at least five functions of the skeletal system. 6.2. Identify the types and locations of skeletal cartilage. 6.3. List and describe the cellular and extracellular organic and inorganic components of bone tissue. 6.4. List the major structural classifications of bones and give examples of each. 6.5. Describe the structural features of long bones and flat bones and explain the functions of red marrow, yellow marrow, articular cartilage, periosteum, and endosteum. 6.6. Compare and contrast the locations and functions of osteoblasts, osteocytes, and osteoclasts. 6.7. Compare and contrast the processes of intramembranous and endochondral bone formation. 6.8. Describe the growth process of long bones at the epiphyseal plate. 6.9. Explain the roles of hormones, vitamins, and mechanical stress in regulating bone growth and remodeling. 6.10. Describe the steps in repair of a bone fracture. 6.11. Describe the homeostatic imbalances in osteoporosis, osteomalacia (Rickets), and Paget's disease. 6.12. Name the two major divisions of the skeletal system (axial and appendicular) and list the bones within each. 6.13. Identify all individual bones and their general markings. 6.14. Describe the structure and function of intervertebral discs. 6.15. Compare and contrast the skull of a fetus with that of an adult. 6.16. Describe the structural and functional classification of joints and give examples of each. 6.17. Describe the structure of synovial joints. 6.18. Describe and demonstrate types of movements of synovial joints. 6.19. Identify and name the different types of joints on models. 6.20. Identify and name the major ligaments on models. 7. Muscular System 7.1. List and describe at least four major functions of muscles. 7.2. Compare and contrast skeletal, smooth, and cardiac muscle. 7.3. Describe the gross structure of a muscle. 7.4. Describe the microscopic structure of a skeletal muscle fiber and the functions of myofibils, sarcoplasmic reticulum, and T tubules. 7.5. Draw and label a sarcomere, including the Z lines, I band, A band, H zone, M line, and thick and thin filaments. List the proteins making up the thick and thin filaments. 7.6. Explain the sliding filament mechanism of contraction. 7.7. List and describe the sequence of events in a muscle contraction-relaxation cycle. 7.8. Define motor unit, and explain how individual muscle fibers are stimulated to contract. 7.9. Describe the anatomy and physiology of the neuromuscular junction. 7.10. Discuss excitation contraction coupling. 7.11. Define muscle twitch, treppe, wave summation, and tetany. 7.12 Define contraction, and differentiate between isometric and isotonic (concentric and eccentric) contraction. 7.13. List the sources of energy for muscle contraction and describe three ways in which ATP is regenerated. 7.14. Define oxygen debt, and explain muscle fatigue and refractory period. 7.15. Compare and contrast slow oxidative muscle fibers and fast glycolytic fibers. 7.16. Describe the factors that influence force, velocity, and duration of contraction. 7.17. Compare and contrast the gross anatomy, the microscopic anatomy, and the contractile functions of skeletal and smooth muscles. 7.18. Describe the functions of prime movers, antagonists, synergists, and fixators. 7.19. List the criteria by which muscles are named, and give examples. 7.20. Identify the major skeletal muscles, using models and cadavers, and name the origin, insertion, and action(s) of each. 7.21. Define lever, name the three types, and describe the advantages of each. 8. Nervous System 8.1. List and describe the major functions of the nervous system. 8.2. Describe the structural and functional organization of the nervous system. 8.3. List and describe the structure and functions of glial cells in the CNS and PNS. 8.4. Describe the structural features of a neuron and the functional role of each part. 8.5. Identify neurons, glial cells, and their parts on models and by microscopy. 8.6. Compare and contrast the myelination of neurons in the CNS with those in the PNS. 8.7. Describe the classification of neurons based on structure and function. 8.8. Define and differentiate nuclei, ganglia, tracts, and nerves. 8.9. Describe how and when regeneration of nerve fibers may occur. 8.10. Define membrane potential, and describe how changes in the electrochemical gradient at the membrane may act as signals. 8.11. Discuss the mechanisms and ions involved in maintaining the resting membrane potential. 8.12. Compare and contrast graded potentials and action potentials. 8.13. Draw an action potential with appropriate voltages; label resting membrane potential, depolarization, repolarization, and hyperpolarization; and explain which ions are moving, and in which direction across the membrane, during each of these periods. 8.14. Explain how action potentials are propagated along axons. 8.15. Define saltatory conduction and compare it with conduction in an unmyelinated neuron. 8.16. Define refractory period and explain the difference between absolute and relative refractory periods. 8.17. Describe a synapse and all associated structures. 8.18. Describe excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs). 8.19. Describe how synaptic signals are integrated and modified, with specific attention to temporal summation, spatial summation, and synaptic potentiation. 8.20. Define neurotransmitter, and list several classes with specific examples. 8.21. Describe the embryonic development of the nervous system. 8.22. Identify the components of the central nervous system (CNS) and peripheral nervous system (PNS). 8.23. Name and identify the major regions of the brain using models and sheep brains. 8.24. Name and locate the ventricles of the brain. 8.25. Identify the major fissures, lobes, gyri, sulci, and functional areas of the cerebral cortex. 8.26. Explain cerebral dominance and lateralization of function. 8.27. Identify and describe commissure fibers, association fibers, and projection fibers, and give examples. 8.28. Identify major basal ganglia (basal nuclei) and describe their general functions. 8.29. Identify the three major subdivisions of the diencephalon, specific structures in each, and state the major function of each. 8.30. Identify the three major subdivisions of the brain stem, specific structures in each, and state the major function of each. 8.31. Identify the major structural features of the cerebellum and describe its functions. 8.32. Locate the limbic system, identify the major structures, and describe its function. 8.33. Describe the structure, function, and location of the reticular formation. 8.34. Describe the gross anatomy of the spinal cord. 8.35. Draw and label a cross section of the spinal cord and state the function of each region. 8.36. Identify and name specific regions of the spinal cord on models, wet tissue, and by microscopy. 8.37. List the major spinal cord tracts, and classify each as sensory or motor. 8.38. Identify the meninges and associated structures, and compare and contrast their structure and function around the brain and spinal cord. 8.39. Describe cerebrospinal fluid, including its formation, circulation, and function. 8.40. Compare and contrast the structural and functional basis of an epidural with a spinal tap. 8.41. Describe the structure and function of the blood-brain barrier. 8.42. Discuss how the absence of a blood-brain barrier in the hypothalamus allows that part of the brain to monitor and control both nervous and endocrine functions. 8.43. List and define the major stages of consciousness. 8.44. Define EKG, list the major wave patterns, and correlate each with brain activity. 8.45. List and describe the stages of sleep, correlate each stage with EKG and physiologic activity, and discuss the importance of sleep. 8.46. List and describe the categories of memory, the stages and formation of memory, and the brain structures involved. 8.47. Discuss the causes, symptoms, and effects of cerebrovascular accidents, Alzheimer's disease, Huntington's disease, Parkinson's disease, and the different forms of epilepsy. 8.48. Describe the structural and functional organization of the peripheral nervous system (PNS). 8.49. List the general receptors and describe the structure, location, and response to specific stimuli of each. 8.50. Describe receptor potentials, generator potentials, and sensory adaptation. 8.51. Define sensation and perception, and describe the processes involved. 8.52. Define nerve and ganglion. 8.53. Describe the structure of a nerve and how nerves are classified. 8.54. List the 12 pairs of cranial nerves; classify each as to sensory, motor, or mixed; indicate the origin, distribution, and major functions of each; and identify each on models and wet tissue. 8.55. Name the 31 pairs of spinal nerves; describe the structural formation of a spinal nerve and the distribution of its rami; and identify the structures on a model . 8.56. Define plexus; identify the major plexuses (cervical, brachial, lumbar, and sacral) and the major nerves arising from each on models and wet tissue. 8.57. List the components of a reflex arc and describe the sequence of events from stimulus to response. 8.58. Describe stretch, Golgi tendon, flexor (withdrawal), and crossed extensor reflexes and give an example of each. 8.59. Describe the plantar reflex and discuss the significance of Babinski's sign. 8.60. Define autonomic nervous system (ANS) and describe the anatomical subdivisions and their general functions. 8.61. Compare and contrast the structure, functions, and neurotransmitters of the somatic, sympathethic, and parasympathetic nervous systems. 8.62. Describe the structure and function of the sympathetic nervous system, including CNS origin, location of ganglia, and major nerve pathways. 8.63. Describe the structure and function of the parasympathetic nervous system, including CNS origin, location of ganglia, and major nerve pathways. 8.64. Explain how dual innervation of most organs by the ANS maintains homeostasis; give specific examples. 8.65. Define cholinergic and adrenergic receptors; list the different subtypes and typical responses of each. 9. Special Senses 9.1. Define special senses and list the special sensory receptors. 9.2. Identify anatomical features of the eye (using models and microscopy), including accessory structures, layers of the eye and their specialized regions, humors, and lens. 9.3. Trace the pathway of light through the eye to the retina, and explain how light is focused for vision. 9.4. Describe the events involved in stimulation of photorececeptors. 9.5. Compare and contrast the structure, function, location, and roles of rods and cones. 9.6. Trace the visual pathway from photoreceptors to the primary visual cortex. 9.7. Identify anatomical features of the ear (using models and microscopy), including structures and fluids in the outer, middle, and inner ear. 9.8. Trace the pathway of sound through the ear to the Organ of Corti. 9.9. Describe the events involved in stimulation of hair cells in the cochlea. 9.10. Trace the auditory pathway from the Organ of Corti to the primary auditory cortex. 9.11. Explain how pitch and loudness are determined and the source of sounds is located. 9.12. Identify the structures for balance in the vestibule and semicircular canals. 9.13. Explain how the structures for balance maintain dynamic and static equilibrium. 9.14. Identify the structure and location of gustatory receptors (using models and microscopy), explain how these receptors are activated, and trace the pathway for taste from receptors to the gustatory cortex. 9.15. Identify the structure and location of olfactory receptors (using models and microscopy), explain how these receptors are activated, and trace the pathway for smell from receptors to the olfactory cortex. 10. Endocrine System 10.1. Compare and contrast the general structure and function of the endocrine and nervous systems. 10.2 List and identify the major endocrine organs. 10.3. Define hormone and describe how hormones are classified chemically. 10.4. Describe the two major mechanisms by which hormones interact with cells, and discuss how each mechanism is dictated by hormone chemistry and the plasma membrane. 10.5. Describe the steps in direct gene activation. 10.6. Describe the steps in the cAMP and PIP second messenger pathways. 10.7. Describe the structural and functional relationship between the hypothalamus and the pituitary gland. 10.8. List the hormones produced by each endocrine organ. 10.9. Describe the production, regulation of release, and effects for each major hormone, including stimulus, target, response, and feedback as well as any homeostatic imbalances (hyper- or hyposecretion) 10.10. Compare and contrast the symptoms, causes, treatment, and pathology of Type I and Type II diabetes mellitus Please note that learning outcome shown in gray will be discussed as time permits. Acknowledgement form It is your responsibility to complete and submit the Biology 141 Syllabus Acknowledgement Form on blackboard. This form will be available at the start of classes within the BIO141 Ready Quiz. Failure to submit in this form will result in withdrawal from the course.