1. Course
2-4032210-1 Clinical Biochemistry (‫)ביוכימיה קלינית‬, Faculty of Health
Sciences, Department of Nutrition, B.Sc. in Nutrition, 3rd year.
2. Schedule
2 hours /week
3. Lecturer
Dr. Ruth Birk, Blg.6, room 6.2.21 Tel: 03-9076594
E-mail: 972-3-9076594
4. Teaching assistant/tutor
None
5. Course goal
a. teach students the physiological and pathological principles
regarding biochemical investigations
b. Understand different biochemical parameters and interpretate of results
and the clinical applications and diagnosis.
6. Prerequisites
Biochemistry
Molecular biology
Pathophysiology
7. Method of instruction
Frontal lectures
8. Course plan
Subjects covered in course:

Introduction, roles of biochemical laboratory. Mechanization and
automation in clinical biochemistry

Biochemical analyses in urine

Clinical biochemical analyses of proteins, plasma protein spectrum.
Analytical methods

Clinical biochemistry of hematology, including: RBC,WBC and platelets.

Laboratory diagnostics of hematology clinical laboratory results

Blood gases, acid-base balance in clinical biochemistry

Electrolytes and their determination in clinical laboratory

Cytokines and their clinical importance

Bone metabolism - clinical and laboratory approaches

Quality control in clinical laboratories. Total laboratory uncertainty.
Accuracy and precision. Selection and optimalisation of laboratory methods.
Clinical evaluation of laboratory methods.
Requirements: Lectures attendance.
9. Course requirements:
Attendance
Final exam
10. Course grading:
100%- final exam
11. Main textbook and additional text books
-Gaw A, Murphy M, Cowan R, O'Reilly DSt. J., Stewart M, Shepherd J.
Clinical Biochemistry - An Illustrated Colour Test", 4th Edition. Churchill
Livingstone, 2004
-Bishop ML., Fody EP., Schoeff LE.. Clinical Chemistry: Principles,
Procedures. Lippincott Williams & Wilkins; 5th edition
-Bettelheim, F., Brown, W., Campbell, M. & Farrell, S. (2009).
Introduction to General, Organic and Biochemistry. (9th ed.) Brooks Cole.
- Selected reprints of current literature.
12. Reading list
See section 11
13. Required material for the examination
Class notes
Text book
Student's presentations