BACTERIA REPRODUCTION NOTES Name______________________________ Blk ___ Date___________ Binary Fission – 1 bacterium splits into 2 identical bacteria; similar to mitosis. Binary means 2, fission means split. Use the graph below to chart the growth of bacteria after 8 HOURS. The x-axis should be numbered with the time. The y-axis will be the bacteria growth – you will need to number the x-axis by 6,000 for the growth. 1. Why do you need to use such large Time # of (hrs) bacteria numbers on the y-axis? 0 1 __________________________ 0.5 2 __________________________ 1 4 __________________________ 1.5 8 2. What would the number be after 10 2 16 hours? 2.5 32 __________________________ 3 64 3. Why would it be important to begin 3.5 128 antibiotics sooner, than later? 4 256 __________________________ 4.5 512 __________________________ __________________________ 5 1024 __________________________ 5.5 2048 4. How would changing the speed of 6 4096 the binary splitting affect the 6.5 8192 disease? 7 16384 __________________________ 7.5 32768 __________________________ 8 65536 __________________________ Above is Unlimited Growth: After every 30 minutes the population doubles. There is nothing stopping or slowing the reproduction of the bacteria. Growth starts slowly then explodes. This is called exponential growth and all bacteria exhibit this. Tuberculosis Bacteria Population with Immune Response over Time 20000 18000 16000 14000 Time (days) TB Bacteria with Immune Response: The TB bacteria show exponential growth until the 8th day when the body’s immune response kicks in and fights back. The response gradually decreases the bacteria’s population. 5. If patient fails to give the body enough rest, fluids, and food what would happen to the graph? ___________________________________ ___________________________________ 6. Would your immune system always begin fighting an infection at the same time? Why/Why not? ___________________________________ 12000 10000 IMMUNE RESPONSE 8000 6000 4000 2000 0 0.0 2.0 4.0 6.0 8.0 10.0 # of bacteria 12.0 14.0 16.0 Tuberculosis Bacteria Population with Immune Response & Antibiotics over Time 20000 18000 IMMUNE RESPONSE & ANTIBIOTICS 16000 Time (days) 14000 12000 10000 8000 6000 4000 2000 0 0.0 2.0 4.0 6.0 8.0 10.0 # of bacteria 12.0 14.0 16.0 TB Bacteria with Immune Response & Antibiotics: Antibiotics are medicines that kill bacteria only. At first the TB bacteria show exponential growth. On the 8th day antibiotics are started and the immune response also kicks in. This results in a sharp decrease in the TB bacteria population until they are finally wiped out on the 15th day. 7. When in this series do you hypothesis the patient would begin to “feel well”? _________________________________ 8. How would taking more medicine impact this process? _________________________________ # of bacteria Tuberculosis Bacteria Population with Immune Response & TB Bacteria with Immune Response & Misuse of Antibiotics over Time Misuse of Antibiotics: At first the TB bacteria show exponential 20000 IMMUNE RESPONSE & growth. On the 8th day antibiotics are 18000 ANTIBIOTICS started, joining the immune system’s 16000 response in the fight against the bacteria. 14000 This results in a sharp decrease in the 12000 bacteria population. One the 11th day 10000 antibiotics are stopped by the patient 8000 because they were feeling better – this is 6000 premature – the prescription was not IMMUNE RESPONSE 4000 finished. This results in a gradual 2000 decrease in the bacteria population because only the immune response is 0 0.0 2.0 4.0 6.0 8.0 10.0 12.0 14.0 16.0 killing the bacteria. This can also result in Tim e (days) the bacteria that lived through the antibiotics adapting to those antibiotics and evolving into being immune from the antibiotics. The bacteria could also regain strength and further impact the patient’s health. 9. What are bacteria called that learn and evolve tactics for surviving antibacterial prescriptions? ____________________________________________________________________________________________