SUBSTANCE MISUSE SYNAPSE TOLERANCE PHYSICAL DEPENDENCE PSYCHOLOGICAL DEPENDENCE WITHDRAWAL CRAVING The intake of drugs in quantities that are potentially damaging to physical or mental health. The junction between two neurons. Neurotransmitters are released by the neuron on one side of the gap and then taken up by the neuron on the other side. Refers to the way the body continues to adapt to a substance. To have the same affect more and more of the substance is needed. Body becomes used to the drug and needs it for normal functioning. When people feel compelled to take a substance - they rely on it to help them feel good. The term for miserable symptoms that are experienced when someone stops using a substance on which they have become physically or psychologically dependent. A strong desire to consume a substance. REWARD PATHWAY The part of the brain which becomes inhibited with continued heroin use DOPAMINE The key neurotransmitter involved in rewards and feelings of pleasure STIMULANT HALLUCINOGEN Drugs which increase the frequency of nerve impulses and make you feel more alert and energised These drugs change a person’s perception of the world, distorting what is heard or seen, or leading to a person experiencing things that do not really exist SEDATIVE NEUROTRANSMITTER DENTRITE HEROIN OPIATES ITCHY BLOOD A drug that induces calmness or sleep chemicals that transmit signals from a neuron to a target cell across a synapse A short branched extension of a nerve cell, along which impulses received from other cells at synapses are transmitted to the cell body A drug which is a natural substance extracted from the opium poppy, acts as a strong painkiller. The name for types of drugs which are made from the opium poppy A symptom which results in heroin addicts continuously scratching their skin causing cuts and bruises. PRO-SPECIESISM The idea that we must do all that we can to protect our own kind Anthropomorphism The attribution of human characteristics or qualities or behaviour to animals REDUCTIONISM NICOTINE SMACK In animal testing, this means reducing animals to inconsequential beings as parts that are tested on rather than whole animals A highly addictive drug that is the main component of tobacco. A street name for heroin SELF-ADMINISTRATION BREEDING STRESS PETA METHADONE MONOZYGOTIC MAINTENANCE The method used in Olde and Milner’s study linking rats behaviour to addiction in humans High rates of this is a key reason why rodents are most commonly used in animal research The independent variable used in Najaraja’s research on ethanol intake. The most well-known organisation who campaign against the use of animals in research Synthetic drug used to treat heroin addiction The name for identical twins, which are often used in evidence for/against genetics as a theory The opposite of abstinence and a common treatment for drug addiction to prevent negative withdrawal