CURRICULUM VITAE STEVEN MICHAEL ANDERSON, PhD PLACE AND DATE OF BIRTH: Fergus Falls, Minnesota, July 7, 1954 EDUCATION: Fergus Falls Community College St. Cloud State University Iowa State University A.A. 1974 B.A. 1976 Ph.D. 1981 EXPERIENCE: Graduate Research Assistant, Iowa State University 1977-81 Postdoctoral Fellow, Waksman Institute of Microbiology, Rutgers University 1981-84 Assistant Professor, Department of Biology, University of North Carolina at Greensboro 1984-89 Adjunct Assistant Professor, Department of Biology, University of North Carolina at Greensboro 1990-98 Associate Director, Department of Molecular Pathology, Roche Biomedical Laboratories, Inc. 1990-92 Director, Department of Molecular Pathology/Immunohistochemistry Roche Biomedical Laboratories, Inc. 1993-94 Technical Director, Oncology, Roche Biomedical Laboratories, Inc. 1995-96 Director, Oncology and Infectious Diseases, Laboratory Corporation of America 1996-97 Senior Technical Director, Center for Molecular Biology and Pathology 1997-2000 Associate Vice President, Laboratory Corporation of America 1998-2000 Vice President, Chief Scientific Officer, Molecular Diagnostics Laboratory Corporation of America 2000-02 Chief Scientific Officer and Director of Operations, ViroMed Laboratories; Vice PresidentChief Scientific Officer, Molecular Diagnostics Laboratory Corporation of America 2002-06 December 2009 1 National Director of Research and Development, Senior Vice President Laboratory Corporation of America 2006-2008 Chief Scientific Officer for Oncology and Genetics, Director of OperationsCenter for MolecularBiology and Pathology, Senior Vice President, Laboratory Corporation ofAmerica 2008Director of Operations, Monogram Biosciences 2009- JOB RESPONSIBILITIES FOR MOST RECENT POSITIONS Senior Vice President, Chief Scientific Officer for Oncology and Genetics, Director of Operations, Center for Molecular Biology and Pathology and Monogram Biosciences. Provide scientific leadership, including the evaluation and implementation of new diagnostic technologies and applications for the areas of Oncology, Genetics and Molecular Infectious Disease testing. Coordination of science and operations across all Oncology and Genetic testing laboratories. Responsible for all aspects of laboratory testing including evaluation of new technology, development of new diagnostic assays, quality assurance and laboratory operations at the Center for Molecular Biology (Research Triangle Park, NC) and Monogram Biosciencs (South San Franciso, CA). The Center for Molecular Biology and Pathology offers cutting edge technologies in the areas of Genetics, Infectous Disease and Oncology. Direct reports include clinical laboratory directors, laboratory general manager, and quality assurance department. Monogram Biosciences offers genotyping and phenotyping in Virology and molecular diagnostics in Oncology. Direct reports include Directors of Research and Development and Laboratory Operations. Senior Vice President, National Director of Research and Development, Laboratory Corporation of America Responsible for the coordination and implementation of Research and Development activities throughout the LabCorp system. This includes evaluation of technology opportunities and applications, prioritization of projects, standardization of assay validation and development studies, review of scientific data and coordination of implementation of new technologies. Director of Operations, Chief Scientific Officer, ViroMed Laboratories Responsible for all aspects of laboratory testing including evaluation of new technology, development of new diagnostic assays, quality assurance and laboratory operations. Direct reports include clinical laboratory director, laboratory general manager, and quality assurance department. December 2009 2 Vice President, Chief Scientific Officer for Molecular Diagnostics, Laboratory Corporation of America (LabCorp) Responsible for all aspects of laboratory testing in the areas of Genetics and Oncology. This included the evaluation of new technology, development of new diagnostic assays, principle investigator for specific clinical trials, quality assurance and laboratory operations. Direct reports included loaboratory directors for Cytogenetics, Molecular Genetics, and Oncology. Served as Discipline Director for LabCorp in the areas of Molecular Genetics and Oncology. MEMBERSHIP IN PROFESSIONAL SOCIETIES: American Association for the Advancement of Science American Association of Clinical Chemistry American Association of Tissue Banks American Society for Human Genetics Association for Molecular Pathology American Society for Microbiology Sigma Xi OTHER PROFESSIONAL ACTIVITIES: Instructor, "DNA Literacy for College Educators Workshop", sponsored by Carolina Biological Supply Co., July 1989. Instructor, "Biotechnology for High School Teachers Workshop", sponsored by the North Carolina Biotechnology Center Secondary Education Program, August 1988 and June 1989. Book Reviewer, Harper and Row, Inc. Contributor, Ohio Academy of Science Biotechnology Laboratory Workbook. Contributor, Childrens Science Magazine "Monkeyshines on Health and Science". Planning Committee, Greensboro Area Math and Science Education Center, 1984-1989. Research Coordinating Committee, North Carolina Zoological Park, 1987-1989. Faculty Advisor, Beta Beta Beta Biology Honor Society, 1986-1988. Education Enhancement Grants Advisory Board, North Carolina Biotechnology Center, 19912002 Biotechnology Advisory Committee, Alamance Community College, 1992-2002 Radiation Safety Officer, Center for Molecular Biology and Pathology, Roche Biomedical Laboratories, 1992 - 1996 Continuing Education Director, Center for Molecular Biology and Pathology, Roche Biomedical Laboratories, 1994 - 1996 Quality Process Management Steering Committee, Center for Molecular Biology and Pathology, Roche Biomedical Laboratories, 1995 Clinical Laboratory Information Council, 1995-1996 Center for Disease Control/DynCorp Panel on Quality Assurance Programs for Molecular Genetics Testing 1998-1999 Technical Working Group for Nucleic Acid Standards (TWGNAS), National Institute of Standards and Technology 1999-2000 Her-2/neu Laboratory Testing Advisory Group, Genentech 1999-2003 Coordinator, LabCorp/UNC Clinical Laboratory Sciences, Molecular Biology Program 19992002 December 2009 3 Her-2/neu Immunohistochemistry DAKO Workshop Moderator 2000-01 CAP Inspection Team Leader, 2000Oncology Advisory Group, Bayer Diagnostics, 2000-01 University of North Carolina at Greensboro Scientific Advisory Board 2002 LabCorp Continuing Medical Education Advisory Board 2003Herceptin Diagnostics Advisory Board 2004EDRN Working Group 2008NIH Biomarker Consortium-Circulating Tumor Cells Advisory Group 2008- PUBLICATIONS: Anderson, S., M. Santos and J. McDonald. 1980. Comparative study of the thermostability of crude and purified preparations of alcohol dehydrogenase (E.C.1.1.1.1.) from D.melanogaster. Drosophila Information Services 44: 13-14. McDonald, J.F., S.M. Anderson and M. Santos. 1980. Biochemical differences between the products of the Adh-locus in Drosophila. Genetics 95: 1013-1022. Anderson, S. and J. McDonald. 1980. Relative in vivo stabilities of products of the Adh locus in Drosophila. Genetics 94: 52. Anderson, S.M. and J.F. McDonald. 1981. A method of determining the in vivo stability of Drosophila alcohol dehydrogenase. Biochemical Genetics 19: 411-419. Anderson, S.M. and J.F. McDonald. 1981. Changes in levels of alcohol dehydrogenase during the development of Drosophila melanogaster. Canadian Journal of Genetics and Cytology 23: 305-313. Anderson, S.M., M. Santos and J.F. McDonald. 1981. Selection at the Adh-locus: Adult survivorship in response to ethanol. Experientia 37: 463-464. McDonald, J. and S. Anderson. 1981. Letter to the Editor - A Reply. Genetics 98: 673-675. Anderson, S. and J. McDonald. 1983. Biochemical and molecular analysis of naturally occurring Adh variants in Drosophila melanogaster. Proc. Nat. Acad. of Sci. 80: 47984802. Place, A.R., S.M. Anderson and W. Sofer. 1986. Introns and domains in dehydrogenase genes. in: "Multidomain Proteins - Structure and Evolution". Elsevier Science Publishers. pp. 175-194. Smith, L. and S. Anderson. 1987. Thermostability of Drosophila alcohol dehydrogenase before and after exposure to 2-propanol. Drosophila Information Services 66: 132-134. Anderson, S. 1987. Biotechnology: The renewable frontier. (Book Review). Bios: Quarterly Journal of Biology 58: 82-83. December 2009 4 Barnett, S. and S. Anderson. 1988. The biochemical basis of alcohol adaptation in Drosophila. Genome 33:30. Anderson, S., M. Brown and J. McDonald. 1989. Post-transcriptional regulation of Drosophila alcohol dehydrogenase. Genetics 122: S42. Forng, E., S. Anderson and R. Cannon. 1989. A synthetic medium for Acetobacter xylinum that can be used for isolation of auxotrophic mutants and the study of cellulose biosynthesis. Journal of Applied and Environmental Microbiology 55:1317-1319. Anderson, S. and S. Barnett. 1991. The involvement of alcohol dehydrogenase and aldehyde dehydrogenase in alcohol and aldehyde metabolism in Drosophila. Genetica 83:99-106. Chimera, J.A., S. Anderson, H. Noell and V. Rizk. 1991. Comparison of nucleic acid hybridization with cytologic examination for detection of human papillomavirus infection: An evaluation of ViraPap and ViraType. Clinical Chemistry 37:260-262. Cannon, R. and S. Anderson. 1991. Biogenesis of bacterial cellulose. Critical Reviews in Microbiology 17:435-447. Anderson, S., M. Brown and J. McDonald. 1991. Tissue specific expression of the Drosophila Adh gene: A comparison of in situ hybridization and immunocytochemistry. Genetica 84: 95-100. Body, B.A., S.M. Anderson and T.H. Callaway. 1991. Laboratory testing for sexually transmitted diseases. RBL Monograph on Infectious Disease. Hall, P., S. Anderson and R. Cannon. 1992. Transformation of Acetobacter xylinum with plasmid DNA by electroporation. Plasmid 28:194-200. Ibrahim, G.K., P.E. Gravitt, K.L. Dittrich, S.N. Ibrahim, O. Melhus, J.A. Chimera, S.M. Anderson and C.N. Robertson. 1992. Detection of human papillomavirus DNA in the prostate by polymerase chain reaction and in situ hybridization. The Journal of Urology 148:1822-1826. Troncone, G., S.M. Anderson, C.S. Herrington, M. de Angelis, H. Noell, J.A. Chimera and J. O'D McGee. 1992. Comparative analysis of human papillomavirus detection by dot-blot hybridization and non-isotopic in situ hybridization. Journal of Clinical Pathology 45:866 - 870. Herrington, C.S., S.M. Anderson, G. Troncone, M.L. deAngelis, H. Noell, J. Chimera and J. O'D McGee. 1993. Comparative analysis of human papillomavirus (HPV) detection by PCR and nonisotopic in situ hybridization. J. of Pathology 169:138A. Anderson, S. and T.H. Callaway. 1993. New technologies for the diagnosis of HPV infection. Primary Care and Cancer 13:9-14. December 2009 5 Herrington, C.S., S.M. Anderson, A.K. Graham and J. O'D McGee. 1993. Discrimination of high risk HPV types by in situ hybridization and the polymerase chain reaction. Histochemical Journal 25:191-198. Anderson, S.M., P.K. Brooke, S.L. Van Eyck, H. Noell and W.J. Frable. 1993. Distribution of human papillomavirus type in genital lesion from two temporarily distinct populations determined by in situ hybridization. Human Pathology 24:547-553. Waggoner, S.E., S.M. Anderson, J. Fuller, S. VanEyck, M.C. Luce and A.L. Herbst. 1994. Human papillomavirus detection and p53 expression in clear cell adenocarcinomas of the vagina and cervix. Amer. Jour. Obstet. and Gynecol. 84:404-408. Herrington, C.S., S.M. Anderson, G. Troncone, M.L. deAngelis, S.L. VanEyck, H. Noell, J.A. Chimera and J.O'D. McGee. 1995. Comparative analysis of human papillomavirus detection by polymerase chain reaction and nonisotopic in situ hybridization. Journal of Clinical Pathology. 48:415-419. Anderson S., Ayscue, A., Baker, K., Chatterjee, A. and Lai-Goldman, M. 1995. Detection of human papillomavirus in anogenital biopsies by an automated in situ hybridization assay. American Jounal of Clinical Pathology 104: 337. Day, J.D., DiGiuseppe, J.A., Yeo, C., Lai-Goldman, M., Anderson, S.M., Goodman, S.N., Kern, S.E. and R.H. Hruban. 1996. Immunhistochemical evaluation of HER-2/neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms. Human Pathology 27: 119-124. Waggoner, S.E., S.M. Anderson, M.C. Luce, H. Tahahaski, and J. Boyd. 1996. P53 protein expression and gene analysis in clear cell adenocarcinoma of the vagina and cervix. Gynecologic Oncology 60: 389-394. Wheeler, C.M., C.A. Parmenter, C.E. Greer, S.M. Anderson, C. Stidley, S. Hunble and M.M. Manos. 1997. Repeated measures of HPV and factors affecting DNA detection. Obstetrics and Gynecology 88: 261-268. Olshan, A.F., M.C. Weissler, H. Pei, K. Conay and S.M. Anderson. 1997. Alterations of the p16 gene head and neck cancer: Frequency and association with P53, PRAD-1 and HPV. Oncogene 14:811-818. Alcorn, T.M. and Anderson, S.M. 1998. Applications of Molecular Virology for Prognostic testing in HIV Infection. Advance/Laboratory Medicine 3:46-52. Dula,W. and Anderson, S.M. 1998 Diagnosis and Management of Hepatitis C infection. Advance/Laboratory Medicine 3:65-72. Waggoner S.E., Baurouch, D.A., Anderson, S.M, Leigh, F., and V.G. Zagaja. 1998. Bcl-2 protein expression is associated with resistance to apoptosis in clear cell adenocarcinomas of the vagina and cervix expressing wild type p53. Annals of Surgical Oncology 5:544547. December 2009 6 Anderson S. and Everett T. 1999. HER-2/neu Oncoprotein: A New Target in the Treatment of Breast Cancer. Advance/Laboratory Medicine 8:36-41. McDowell G., Brown T., Papenhausen P., and Anderson S. 2000. Enhanced second trimester maternal serum screening for Down syndrome: Addition of Dimeric Inhibin A. Advance/Laboratory Medicine 9: 2-8, 2000. Liaw K., Hildesheim A., Burk R., Gravitt P., Wacholder S., Manos M., Scott D., Sherman M., Kurman R., Glass A., Anderson S., and Schiffman M. 2001. A prospective study of HPV 16 DNA detection by PCR and its association with acquistion and persistence of other HPV types. Journal of Infectious Disease 183:8-15. Anderson S. and McCune B. 2001. Immunohistochemical Testing for the Determination of HER-2/neu Overexpression. DAKO Connection 3:6-8. Harris L., Liotcheva V., Broadwater G., Rameriz M., Anderson S., Everett T., Harpole D., Moore M., Berry D., Vrendenburgh J. and Bentley R. 2001. Comparison of methods and outcome of HER-2 positivity after high-dose chemotherapy in metastatic breast cancer patients. Journal of Clinical Oncology 19:1698-1706. Anderson S. 2001. Human Papillomavirus and Cervical Cancer. Advance/Laboratory Medicine 10: 90-96. Paik S., Bryant J., Tan-Chiu E., Romond E., Park K., Brown A., Yothers G., Anderson S., Smith R., Wickerman, D., and N. Wolmark. 2002. Real world performance of HER2 testingNational Surgical Adjuvant Breast and Bowel Program experience. Journal of the National Cancer Institute 94: 852-855. Anderson S. 2002 Human Papillomavirus Infections and Cervical Cancer. Microbiology Newsletter 24:113-118. Clinical Sardosy M.F., Schellhammer P, Bokinsky G., Kahn P, Chao P, Yore L, Zadra J, Osher G, Bridge J, Anderson S, Johannson S, Lieber M, Soloway M and K Flomm. 2002. Clinical evaluation of a multi-target fluorescent in-situ hybridzation assay for detection of bladder cancer. J of Urology 168:1950-1954. Bankowski M. and S. Anderson 2003. West Nile Virus Infection: A Review for Clinicians. Advance/Laboratory Medicine 12: 76-82. Alcorn T. and S. Anderson 2004. Automated DNA Sequencing. Molecular Microbiology: Diagnostic Principles and Practices (ASM Press, ed. Pershing DH, Tenover FC, Versalovic, J, Tang YW, Unger ER, Relman DA and TJ White) pp 153-160. Bankowski M. and S. Anderson 2004. Clinical Applications of Real-Time PCR Technology. Clinical Microbiology Newsletter 26:9-15. December 2009 7 Blackwell KL, Dewhirst MW, Liotcheva V, Snyder S, Broadwater G, Lai A, Riggins G, Anderson S, Vredenburgh J, Proia A, and LN Harris. 2004. HER-2 Gene Amplification Correlates with Higher Levels of Angiogenesis and Lower Levels of Hypoxia in Primary Breast Tumors. Clinical Cancer Research 10: 4083-4088. Anderson S. 2005. Human Papillomavirus Advance/Laboratory Medicine. 14: 92-99. and Cervical Cancer: An Update. Mass RD, Press MF, Anderson SM, Cobleigh MA, Vogel CL, Dybdahl N, Lebierman, G. and D. Slamon. 2005. Evaluation of Clinical Outcomes According to HER2 Detection by Fluorescence In Situ Hybridization in Women with Metastatic Breast Cancer Treated with Trastuzumab. Clinical Breast Cancer Research 6: 240-246. Dybdahl N., Lieberman G., Anderson S., McCune, B, Bajamonde A., Cohen R., Mass R., Sanders C. and M. Press. 2005. Determination of HER2 Gene Amplification by Fluorescence In Situ Hybridization and Concordance with the Clinical Trials Immunohistochemical Assay in Women with Metastatic Breast Cancer Evaluated for Treatment with Trastuzumab. Breast Cancer Research and Treatment 93:3-11. Reddy J.C., Barker C.M., Anderson S.M., and P.M. Klein. 2006. Concordance Between Central and Local Laboratory Testing from a Community-Based Clinical Trial. Breast Cancer Research 7:153-157. Anderson S. 2008. Considerations for HCV and HIV Viral Load Testing. Advance/Laboratory Medicine 17s:17. Tutt A., Wang A., Lau K., Gillett C,. Chew K., Rowland C., Dai H., Kwok S., Ryder K., Shu H., Springall R., McCallie B., Kam-Morgan L., Anderson S., Buerger H., Gray J., Bennington J., Esserman L., Hastie T., Broder S., Sninsky J., Brandt B., and F. Waldman. 2008. Risk Estimation of Distant Metastasis in Node-Negative, Estrogen ReceptorPositive Breast Cancer Patients Using an RT-PCR Based Prognostic Expression Signature. BMC Cancer 8:339-377. Iverson AA, Gillett C, Cane P, Santini CD, Vess TM, Kam-Morgan L, Wang A, Eisenberg M, Rowland CM, Hessling JJ, Border S, Sninsky JJ, Tutt, A, Anderson S, Chang SYP 2009. A Single-Tube Quantitative Assay for mRNA levels of Hormonal and Growth Factor Receptors in Breast Cancer Specimens. Journal of Molecular Diagnostics 11: 117-130. Anderson S., 2009. Applications of Microarray Technologies in Anatomic Pathology. Dako Connection 13: 76-79. EDUCATIONAL MATERIALS: Anderson, S.M. 1989. Genetic Engineering. Monkeyshines on Science and Health. 3:10-12. Body, B.A., S.M. Anderson and T.H. Callaway 1991. Laboratory testing for sexually transmitted diseases. RBL Monograph on Infectious Disease. December 2009 8 Cannon, R.E. and S.M. Anderson 1993. Cellulose production by Acetobacter xylinum. The Ohio Science Workbook: Biotechnology pp. 31-33. Anderson, S.M., and R.E. Cannon 1993. Plasmid DNA isolation and characterization. The Ohio Science Workbook: Biotechnology pp. 101-103. Lai-Goldman, M., L.E. Osborne, J. Fuller and S.M. Anderson 1994. New technologies for diagnosis and disease monitoring in patients with chronic myelogenous leukemia. ASCP Check Sample 18:51-65. ABSTRACTS (since 1987): Forng, E.R., S.M. Anderson and R.E. Cannon. 1987. Development of a synthetic medium for Acetobacter xylinum. Annual Meeting of the American Society for Microbiology. Anderson, S., G. Keesler, J. Warren and R. Cannon. 1988. RP4 conjugation between E. coli and A. xylinum. Annual Meeting of the American Society for Microbiology. Fry, D., F. Keegan and S. Anderson. 1988. ADH and ALDOX activity in Drosophila embryos. National Congress on Undergraduate Research. Barnett, S. and S. Anderson. 1988. The biochemical basis of alcohol adaptation in Drosophila. XVIth International Congress of Genetics. Anderson, S., M. Brown and J. McDonald. 1989. Post-transcriptional regulation of Drosophila alcohol dehydrogenase. Annual Meeting of Genetics Society of America. Smith, R., R. Cannon and S. Anderson. 1990. Characterization of a plasmid from Acetobacter xylinum ATCC 27369: Wild type and cellulose-negative mutants. Annual Meeting of the American Society for Microbiology. Chimera, J., Anderson, S., Noell, H. and V. Rizk. 1990. Comparison of nucleic acid hybridization and cytologic examination for the detection of human papillomavirus infection: An evaluation of ViraPap and ViraType. Fourth International Conference on Human Papillomaviruses and Genital Carcinoma. Hall, P., S. Anderson and R. Cannon. 1991. Transformation of Acetobacter xylinum with plasmid DNA by electroporation. Annual Meeting of the American Society for Microbiology. Gravitt, P., H. Noell, P. Brooke, J. Chimera, W.J. Frable and S. Anderson, 1991. A comparison of in situ hybridization and polymerase chain reaction for the detection of human papillomavirus in paraffin-embedded tissue. ASM Conference on Biotechnology. December 2009 9 Parmenter, C.A., H.M. Bauer, T.M. Becker, J. Miller, S. Anderson, M.M. Manos and C.M. Wheeler. 1991. Determinants of genital human papillomavirus infection in a female university population: The New Mexico Experience. International Papillomavirus Conference. Gravitt, P., G. Ibrahim, C. Robertson, S. Ibrahim, O. Melhus, J. Chimera and S. Anderson.1991. Detection of human papillomavirus DNA in prostate by polymerase chain reaction and in situ hybridization. International Papillomavirus Conference. Gravitt, P., H. Noell, P. Brooke, C. Ellington, J. Chimera, W. Frable and S. Anderson. 1991. A comparison of in situ hybridization and polymerase chain reaction for the detection of human papillomavirus DNA in paraffin-embedded tissue. International Papillomavirus Conference. Wheeler, C.M., C.A. Parmenter, C.E. Greer, S. Anderson, C. Stidley, S. Humble and M.M. Manos. 1991. Repeated measures of HPV and factors affecting DNA detection. International Papillomavirus Conference. Ibrahim, G., P. Gravitt, S. Anderson, S. Ibrahim, O. Melhus, J. Chimera and C. Robertson. 1991. Detection of human papillomavirus DNA in prostate by polymerase chain reaction and in situ hybridization. International Society of Urology. Anderson, S. 1992. The polymerase chain reaction overview and clinical applications. American Association for Clinical Chemistry. Anderson, S.M., P.K. Brooke, S.L. Van Eyck, H. Noell and W.J. Frable. 1992. Distribution of human papillomavirus type in archival tissue from 1964-65 and 1988-89. International Papillomavirus Conference. Somers, K.D., G.L. Schechter, M.A. Merrick, G. Carey, M.E. Lopez, S. Anderson, S. Van Eyck, J.S. Hill and T.C. Carey. 1992. p53 mutations in HPV DNA positive cell lines derived from squamous cell carcinoma of the head and neck. International Papillomavirus Conference. Anderson, S.M., P.K. Brooke, S. Van Eyck, H. Noell and W.J. Frable. 1992. Distribution of human papillomavirus types in archival tissues from 1964-65 and 1988-89. ASCP/CAP Fall Meeting. Herrington, C.S., S.M. Anderson, G. Troncone, M.L. de Angelis, H. Noell, J. Chimera and J. O'D McGee. 1993. Comparitive analysis of human papillomavirus (HPV) detection by PCR and nonisotopic in situ hybridization (NISH). Pathological Society of of Great Britain and Ireland Annual Meeting. Waggoner, S.E., S. Anderson, S. VanEyck, M. Luce and A. Herbst. 1993. Human papillomavirus detection and p53 expression in clear cell adenocarcinomas of the vagina and cervix. The American College of Obstetricians and Gynecologists Annual Meeting. December 2009 10 Anderson, S.M., J. Fuller, Y. Liu, H. Noell, K. Ellington and M. Lai-Goldman. 1993. Cellular proliferation in breast carcinomas as determined by MIB-1 immunostaining. ASCP/CAP Fall Meeting. Anderson, S.M., S. Waggoner, S. VanEyck, J. Fuller and M. Luce. 1993. Human papillomavirus detection and p53 expression in clear cell adenocarcinomas. International Papillomavirus Conference. Carey, T.E., S.E. Grenman, R. Grenman, M.J. Worsham, D.L. VanDyck, D.J.S. Hayashida, K.D. McClatchey, C.R. Bradford, J.A. Roberts, K.D. Somers and S.M. Anderson. 1993. UMGCC01, a new HPV-16 positive cell line from a cervical glassy cell carcinoma. International Papillomavirus Conference. Waggoner S., Xu, K. Micetech, Anderson S., DeGeest K., and M. Turyk. 1993. Interleukin-6 production by normal, dysplastic, malignant and HPV 16 tranformed human cervical cells. International Papillomavirus Conference. Anderson S.M., J.L. Becker and P.R. Papenhausen. 1994. Verification of an i(5p) marker chromosome in a mixed Mullerian tumor of the ovary by fluorescence in situ hybridization. FISH: Clinical Applications in Cancer and Genetics. Anderson S., S. Van Eyck, G. Farr and M. Johnson 1994. Detection of Cytomegalovirus in paraffin-embedded tissue by in situ hybridization. American Public Health Association Annual Meeting Anderson S.M., Y. Liu and P.R. Papenhausen 1994. Identification and characterization of marker chromosomes, de novo rearrangements and microdeletions in 100 cases with fluorescence in situ hybridization (FISH). American Society of Human Genetics Papenhausen P.R. and S. Anderson 1994. Diagnostic/prognostic molecular cytogenetic followup applied in satellited marker cases. American Society of Human Genetics. Waggoner, S., S. Anderson, M. Luce, H. Tahahosi, and J. Boyd 1995. P53 expression and gene analysis is clear all adenocarcinomas at the vagina and cervix. Twenty-sixth annual meeting of the Society of Gynecologic Oncologists. Anderson, S., T. Green, A. Ascyue, K. Baker and C.Cooke 1995. Detection of human papillomavirus in a duodenal metastasis by in situ hybridization and the polymerase chain reaction. International Papillomavirus Conference. Olshan, A., M. Weissler, H. Pei, K. Conway and S. Anderson 1995. HPV and alterations of p53, p16 and PRAD-1 in head and neck cancers. International Papillomavirus Conference. Anderson, S., A. Ayscue, K. Baker, A. Chatterjee and M. Lai-Goldman 1995. Detection of human papillomavirus in Anogenital biopsies by automated in situ hybridization. ASCP/CAP Fall Meeting. December 2009 11 Tepperberg, J.H., I.K. Gadi, S.M. Anderson, M.R. Rossi, A. DeJesus and P.R. Papenhausen 1995. Molecular analysis of a rare ring chromosome in a young girl with mild features of Down syndrome. American Society of Human Genetics. Papenhausen, P.R., M. Luce, I.R. Gadi, J.H. Tepperberg, and S.M. Anderson 1995. Molecular analysis of SRY/ZFY in cases of phenotype/genotype sex discordance. American Society of Human Genetics. Harris L.N., Liotcheva V., Broadwater G., Anderson S., Vrendenbergh J., Rameriz M., MooreJoshi M., and R. Bentley 1999. Method of measuring ERB2 gives different results in predicting response to high-dose chemotherapy (HDC) in breast cancer patients. American Society of Clinical Oncology. Pratt V., Brown, T., Kam-Morgan L., Eisenberg M. and Anderson S. 1999. Mutation detection and referral testing for cystic fibrosis. Association for Molecular Pathology Annual Meeting. Mass R., Sanders C., Kasian C., Everett T., Johnson L. and Anderson S. 2000. The concordance between the clinical trials assay (CTA) and fluorescence in situ hybridization (FISH) in the Herceptin pivotal trials. American Society of Clinical Oncology. Blackwell K., Liotcheva V., Haroon Z., Fung K., Broadwater G., Anderson S., Vredenburgh J., Proia A., Greenberg C., Dewhurst M., and Harris L. 2000. Her-2 Gene Amplification Correlates with Higher Levels of Angiogenesis in Primary Breast Tumors. American Society of Clinical Oncology. Pratt V., Brown, T., Kam-Morgan L., Eisenberg M. and Anderson S. 2000. Mutation detection and referral testing for cystic fibrosis. American Society of Human Genetics Annual Meeting. Mass R.D., Press M., Anderson S., Murphy M., and Slamon D. 2001. Improved Survival Benefit from Herceptin (Trastuzumab) in Patients Selected by Fluorescence In Situ Hybridization. American Society of Clinical Oncology Annual Meeting. Levine E.A., Inman J.L., White W., Pettanati M., Anderson S., and T. Kute. 2001. Absence of HER-2/neu Expression in Metastatic Melanoma. American Society of Clinical Oncology Annual Meeting. Sardosy M. , Schellhammer P., Kahn P., Zadra J., Bridge J., Johansson S., Anderson S., and K. Flom. 2001. Clinical Evaluation of a multi-target fluorescent in situ hybridization (FISH) assay for bladder cancer detection. American Urology Association Annual Meeting. Mass R., Press M., Anderson S., and D. Slamon. 2001 Improved survival benefit from Herceptin (trastuzumab) and chemotherapy in patients selected by fluorescence in situ hybridization. 24th Annual San Antonio Breast Cancer Symposium. December 2009 12 Press M., Slamon D, Cobleigh M, Vogel C, Zhou J-Y, Anderson S, Liberman G, and R. Mass. 2002. Improved clinical outcomes for Herceptin treated patients selected by fluorescence in situ hybridization. USCAP Annual Meeting. Press M, Anderson S, Dybdal N, Lieberman G, and R Mass. 2002. Fluorescence in situ hybridization (FISH) rior to immunohistochemistry (IHC) for determining HER-2 status: The Herceptin experience. USCAP Annual Meeting. Eberhard D A, Huntzicker E and S. Anderson 2002. Epidermal growth factor receptor immunohistochemistry (EGFR IHC): Assay selection and application to breast cancers. ASCO Annual Meeting. Klein P, and S. Anderson. 2002 FISH identifies HER-2+ patients missed with immunohistochemistry. ASCO Annual Meeting. Belzer S., Anderson S, and MJ Bankowski 2002. Parvovirus B-19 DNA PCR as an adjunct to serological testing. Association for Molecular Pathology Annual Meeting. Anderson S. and P Klein 2002. Concordance between local labs and a central lab using FISH and IHC for HER-2 testing. San Antonio Breast Cancer Symposium. Winer E, Cobleigh M., Dickler M, Miller K, Fehrenbacher L, Jones CM, Anderson S, Eberhard D, and R. Justice. 2002. Phase II multicenter study to evaluate the efficacy and safety of Tarceva (erlotinib HCL, OSI-774) in women with previously treated, locally advanced, or metastatic breast cancer. San Antonio Breast Cancer Meeting. Anderson S, Gilkerson E, and P Klein. 2003. Concordance between local labs and a central reference lab using FISH and IHC for HER2 testing. Annual Meeting of the United Stated and Canadian Academy of Pathology. Bankowski MJ, Belzer SW, Lembke BD, and SM Anderson. 2003. Standardization of nucleic acid amplification using the MagnaPure LC and the Light Cycler for real-time PCR detection of polyomaviruses. Clearwater Virology Symposium. Bankowski MJ, Belzer SW, Lembke BD and SM Anderson. 2003. . Standardization of nucleic acid amplification using the MagnaPure LC and the Light Cycler for real-time PCR detection of herpes viruses. Clearwater Virology Symposium. Bankowski MJ, Belzer S, Lembke B, Hodges-Savola C., Wold K, and S Anderson. 2003. Detection of human human IgM and IgG antibody to West Nile Virus (WNV) using indirect immunofluorescence antibody (IFA) testing during the 2002 WNV season. Annual Meeting for the American Society for Microbiology Bankowski MJ, Belzer S, Lembke B and S Anderson. 2003. Real-time PCR (Light-Cycler) detection of West Nile Virus (WNV) RNA in human serum and CSF during the 2002 WNV season. Annual Meeting for the American Society for Microbiology December 2009 13 Anderson SM, Gocke D, Belzer SW, Gamble A, Campanella C. and MJ Bankowski. 2003. Detection of Hepatitis C Virus RNA in cadaveric serum or plasma samples using nucleic acid amplification. Annual Meeting of the American Association of Tissue Banks. Romain C, Ybarra A, and S.M. Anderson 2003. Evaluation of an Oligonucleotide Ligation Assay for Cystic Fibrosis Testing. Annual Meeting of the Association for Molecular Pathology. Lembke B., Belzer S, Anderson S. and MJ Bankowski 2003. Standardization of Real-time nucleic acid amplification of Bordetella. Annual Meeting of the Association for Molecular Pathology. Bankowski MJ, Hodges-Savola C, Zeller J, White J, and S.M. Anderson. 2004. DirectigenTM Flu A/B, Shell Vial, and Influenza Strain Challenge for the 2003-2004 Respiratory Season. Clearwater Virology Symposium. Bankowski MJ, Hodges-Savola C., Belzer S.W., Lembke B. and S.M. Anderson 2004. ELVIS, Viral Culture, and Real-Time PCR for the Direct Detection of Herpes Simplex Virus in Clinical Specimens. Clearwater Virology Symposium. Bankowski MJ, Belzer S, Lembke B and SM Anderson. 2004 Prevalence of Norovirus RNA in Stool Cases of Human Gastroenteritis Where Rotavirus and other Stool Testing is Negative. Annual Meeting of the American Society for Microbiology Anderson SM, Belzer S, Lembke B, and MJ Bankowski. 2004 Real-time PCR (Light Cycler) Multiplex Detection of Polyomavirus (BK and JC) DNA in Human Blood, CSF and Urine Specimens. Annual Meeting of the American Society for Microbiology. Anderson S.M, Reddy J, Lieberman G, Rai S, and P. Klein. 2004. Concordance Between Central and Local Lab IHC and FISH HER2 Testing in a Community-Based Trial of First-Line Trastuzumab Plus a Taxane in HER2+ Metastatic Breast Cancer. American Society of Clinical Oncology Annual Meeting. Bankowski M.J., Belzer, S.W., Lembke B.D., Gocke D., Gamble A., and S.M. Anderson. 2004. Preclinical Validation of the COBAS AmpliscreenTM Test for the Amplification and Detection of HIV-1 and HCV in Tissue Donor Blood Specimens. American Association of Tissue Banks Annual Meeting. Anderson S.M., Reddy J., and P.M Klein. 2004 Concordance Between Central and Local Laboratory Immunohistochemistry and Fluorescence In Situ Hybridization HER2 Testing in a Community-Based Trial of First Line Trastuzumab plus Taxane in HER2 Positive Metastatic Breast Cancer. Genentech BioOncology Solid Tumor Investigator Meeting. Bankowski M, Anderson S, Belzer S. and B. Lembke. 2004. Amplification and Detection of HIV-1 and HCV in Tissue Donor Blood using NAT PCR Testing. American Association of Blood Banks Annual Meeting. December 2009 14 Bankowski, M, Belzer S, Lembke B, Abelson M, and S. Anderson. 2004. Amplification and Detection of Hepatitis C Virus (HCV) in Tissue Donor Specimens Using the COBAS HCV Amplicor and AmpliscreenTM Tests. Association for Molecular Pathology Annual Meeting. Bankowski, M., Hodges-Savola C., Belzer S., Lembke B. and S. Anderson. 2005. Evaluation of a Real-time PCR Test for the Direct Detection of Influenza Virus. Clearwater Virology Symposium. Bankowski M., Belzer S., Lembke B., Mix L, and S. Anderson. 2005. Direct Detection of Human Metapneumovirus in Clinical Specimens Using Real-Time PCR. Clearwater Virology Symposium. Bankowski M., Belzer S., Lembke B, and S. Anderson. 2005. The Extraction of Nucleic Acids from a Variety of Viruses and Clinical Specimens Using the MDx BioRobot and a Modification of the Viral Kit. Clearwater Virology Symposium. Bankowski M., Belzer S., Lembke B., Johnson S., and S. Anderson. 2005. Evaluation of the MultiCode-RTx Using Real-Time PCR for the Detection of Enterovirus in Clinical Specimens. Clearwater Virology Symposium. Bankowski M., Belzer S., Lembke B., Mix L., Gumz T., and S. Anderson. 2005. Detection of Trichomonas vaginalis in Clinical Specimens Using Real-Time PCR Compared to Culture Isolation. Annual Meeting of the American Society of Microbiology. Tran H. and S. Anderson. 2006 Carrier and Donor Screening for Gamete Donors: Test Utilization in Conjunction with Recommendations and Guidance. American College of Medical Genetics Annual Meeting Zeimis R., Belzer S., Mix L. and S. Anderson. 2006 Evaluation of Bacterial Identification Systems using the Vitek2 Compact and Biolog Systtems Compared to 16S Ribosomal RNA Sequencing. American Society of Microbiology Annual Meeting/ Bankowski M., Belzert S., Lembke B., Loeffelholz M, Hayden R. and S. Anderson. 2006. Evaluation of a Real-Time PCR Multiplex for the Direct Detection of Influemza Virus Type A, Influenza Virus Type B and RSV in Clinical Specimens. Clearwater Virology Symposium Annual Meeting Bankowski M,, Belzer S,, Lembke B., Loeffelholz M, and S. Anderson 2006 Validation of a Real-Time PCR Test for the Deteciton and Subtyping of Influenza A Virus in Clinical Specimens. Clearwater Virology Symposium Annual Meeting. Wang A., Chew K., Chang J, Lau K., Santini C. ,Vess T, Eisenberg M, Bennington T., Anderson S., Sninsky J., Waldman F., and J. Hessling 2006. Assessment of Hormone Receptor Status in Breast Cancer by Immunohistochemical and Gene Expression Assays. AACR Cancer Biomarker Conference. December 2009 15 Anderson SM, Belzer SW, Loeffelholz MJ, Lembke BD and MJ Bankowski. 2006 Validation of a Real-Time PCR Method for the Direct Detection of Enterotoxigenic E. coli (ETEC) in Stool Specimens. Association for Molecular Pathology Annual Meeting. Sninsky, J, Gillett, C, Lau K, Wang A, Santini C, Sigua C, Iverson A, Vess T, Kim W, Kwok S, Springhall R, Ryder K, Kam-Morgan L, Eisenberg M. Anderson S, Chang S-Y, Broder S and A Tutt. 2007 Performance of an RT-PCR multi-gene prognostic signature for distant metastasis from N-, ER+ breast cancer patients on N-, ER+ Tamoxifen-treated patients using FFPE sections. Miami Breast Cancer Symposium Iverson A., Santini C., Vess T., Kam-Morgan L., Wang A., Eisenberg M., Anderson S., Sninsky J., Chang S., and J. Hessling. 2007. Multiplex TaqMan assay for quantitative detection of hormone receptors in breast cancer fixed sections. American Association of Clinical Chemistry Annual Meeting. Nye M.B., Amos R.N., Christensen E., Anderson S., and B.A. Body. 2008 Performance of a Laboratory Developed Test Using Invader HPV ASR and GPR components on 1000 Consecutive ThinPrep Specimens with Hybrid Capture 2 and Cytology Results. Clearwater Virology Annual Symposium Nye M.B., Amos R.N., Christensen E., Anderson S., and B.A. Body. 2008 Evauation of Invader HPV ASR as an Alternative for ThinPrep Specimens Quantity Not Sufficient for Hybrid Capture 2 Testing. Clearwater Virology Annual Symposium Wang A., Rowland C. , Chew K., Chang S.-Y., Broder S., Bennington J., Gray J., Anderson S., Sninsky J., and F. Waldman. 2008. Comparing prognostic value of Ki-67 labeling index with a 14-gene expression signature in early-stage breast cancer. AACR EORTC Meeting. Anderson S., Kam-Morgan L., Chatterjee A. and M. Eisenberg. 2008. Gene Methylation Markers in Prostate Cancer. ASCO-NCI-EORTC Molecular Markers in Cancer Meeting Sninsky J., Wang A., Rowland C., Chow K., Anderson S., Gray J., Broder S., Bennington J., and F. Waldman. 2008. Comparing Prognostic Value of Ki-67 Labeling Index with 14 Gene Expression Signature in Early Stage Breast Cancers. ASCO-NCI-EORTC Molecular Markers in Cancer Meeting. Iwata H, Wang A, Gillett C, Higashimoto H, Lagier R, Rowland C, Anderson S, Broder S, Sninsky J, and A. Tutt. 2009 A 14-gene prognosis signature predicts metastasis risk in node-negative, estrogen receptor-positive, Tamoxifen-treated breast cancer in different ethnogeographic regions. Miami Breast Cancer Symposium Iwata H, Wang A, Gillett C, Higashimoto H, R. Lagier2, Rowland C, Anderson S, Broder S, Sninsky J, and A. Tutt 2009. Risk stratification of distant metastasis by progesterone receptor and a 14-gene expression signature for prognostic value in tamoxifen-treated breast cancer. San Francisco Breast Cancer Symposium. December 2009 16 Anderson S, Kam-Morgan L, Kallam E, Cai L, and M Eisenberg. 2009. Promoter Methylation of the MGMT Gene Determined by Quantitative Methylation Specific PCR. ASCOEORTC-NCI Annual Meeting. Cai L,Kam-Morgan L, Eisenberg M, and S Anderson. 2009. Detection of K-RAS Oncogene Mutations Using PCR and Pyrosequencing Methods. ASCO-EORTC-NCI Annual Meeting. Papenhausen P, Schwartz S, Tepperberg J, and S. Anderson. 2009. Homozygotic Blocks Reveal LD Associated with UPD in SNP Arrays. Association of Molecular Pathology Annual Meeting. Weck K, Irvin W, Friedman K, Anderson S, Olajide O, Dees E, Peppercorn J, Chiu M., Walko C, Evans J, McCleod H, and L. Carey. 2009. Use of the Roche Amplichip for CYP2D6 Genotyping to Determine Tamoxifen Dose in a Multiracial Breast Cancer Population. Association of Molecular Pathology Annual Meeting. Anderson S, Kam-Morgan L, Kallam E, Chatterjee A, and M. Eisenberg. 2009. Promoter Methylation of GST-P1 and APC in Prostate Cancer. Association of Molecular Pathology Annual Meeting. Kam-Morgan L, Kallam E, Cai L, Eisenberg M and S. Anderson. 2009. Promoter Methylation of the MGMT Gene Determined by Quantitative Methylation Specific PCR. Association of Molecular Pathology Annual Meeting. Irvin W, Walko C, Dees E, Chiu W, Lange L, Olajide O, Raab R, Corso S, Evans J, Weck K, Peppercorn J, Anderson S, Friedman K, Ogburn E, Desta Z, Flockhart D, McLeod H and L. Carey. 2009. San Antonio Breast Cancer Meeting. December 2009 17