The clinical observation of treatment effects of Traditional Chinese Medicine on 320 cases of Betch’s disease By: Wangrong, Shi Huaili, etc. AnBoNa (Beijing) Sci.&Tech. Co., LTD. BaiCaoJiSheng Traditional Chinese Medicine Clinic Objective: To observe the curative effects of Chinese medicine treatment on Betch’s disease. Methods: Using "special prescription for Betch’s disease treatment" to treat 320 patients with Betch’s disease, the course of treatment was 1 to 2 months. Results: Of 320 cases, 231 cases of clinical cure, 64 cases were markedly improved(symptoms disappeared), 97.8%. improved in 18 cases, and 7 cases were ineffective, the total effective rate was The clinical observation showed that the curative effect was remarkable. Conclusion: The "special prescription for Betch’s disease treatment" is effective formulas to treat the Betch’s disease, and be worth promoting widely in clinical practice. Key words: traditional Chinese medicine (TCM); Betch’s disease; traditional Chinese medicine therapy. Chinese library catalogue number: R73r7. Document ID code: B 1007-599-11-031 (2206) Article number: Betch 's disease (BD), is a common disease occurs mostly in young adults, which mainly leading to oral ulcers, genital ulcers, eye inflammation and skin lesions, involved a verities of system in the body. The disease is characterized by chronic, progressive, recurrent features. The cause of the disease may be associated with infections, immune disorders, genetic factors, trace elements and other related [1]. Currently, there were no specific methods for the treatment of the disease, corticosteroids and immunosuppressant were used in the routine therapy, but with greater long-term side effects and easy to relapse after drug withdrawal. The "special prescription for Betch’s disease treatment" was invented by several doctors including Wangrong, Shi Huaili, etc, who worked in BaiCaoJiSheng traditional Chinese medicine clinic, according to many years’ clinical experience. The "special prescription for Betch’s disease treatment" is based on 12 plant components. Since January 2009, 320 cases of Betch’s disease has been chosen and treated by "special prescription for Betch’s disease treatment", a remarkable clinical curative effect was obtained. 1.1 General information Totally, 320 cases in this group, 26 to 65 years of age, the average age is 38 years. All the selected patients were clinic patients and with the symptoms of recurrent oral ulcers, multiple- genital ulcers and eye inflammation. Of these cases, 289 patients with different degree of eye inflammation, 316 cases with skin lesions, 242 cases of pin-prick test positive result, 195 cases had symptoms of other systems. All 320 cases had a history of glucocorticoid medication. 1.2 The diagnostic criteria of Betch’s disease All the cases were diagnosed according to the diagnostic criteria created by the world organization of Betch’s disease, that is: (1): recurrent oral ulcers occurred more than 3 times/year; (2) recurrent genital ulcer; (3) eye lesion: eye pigment membrane inflammation, vitreous opacity, retinal vasculitis; (4) skin lesions: skin nodular erythema, pseudo-folliculitis, purulent pimples, acne-like rash (without using glucocorticoid); (5) the pin-prick test positive. All the cases can be confirmed with the symptom of (1) combined with 2 of the remaining 4 items above. 1.3 Treatment With ingested "special prescription for Betch’s disease treatment": Glabrous Greenbrier Rhizome, Lily, Fructus Mume, Liquorice, Tripterygium, Angelica Root, Honeysuckle, etc., 1 does every day, making decoction and given in divided doses, 2 times a day, 15 days was a course of treatment, After 3-5 courses of treatment, curative effect can be judged according to the patients’ conditions. The externally applied agent for Ulcer: Herba Epimedii, Catechu, Shawl, Borneol and so on, 3 to 4 times daily. For eye lesions,using amikacin eyedrops to treat, 3 times a day. 2 Clinical observation of effects 2.1 To judge comprehensively according to the results of examination and clinical symptoms improved. Clinically cured: clinical symptoms and signs disappeared completely, follow-up 2 years without recurrence. Valid: clinical symptoms and signs disappeared. Improved : clinical symptoms relieved. Uneffective: without any clinical improvement. 2.2 The treatment results Results: of the 320 patients, 231 cases were clinically cured, follow-up 2 years without recurrence; 64 cases were valid while 18 cases were improved, 7 cases were ineffective, the total effective rate was 97.8%. Curative effect is remarkable. Conclusion: "special prescription for Betch’s disease treatment" is a effective formulas to treat the Betch’s disease, and be worth promoting widely in clinical practice. Discussion: the Betch’s disease is a chronic, progressive, recurrent, multi-system damaging disease, with a pathological basis of vasculitis in small vessels, often occurred in oral cavity, skin, genital, digestive tract, joint with diverse clinical manifestations. The cause of disease may be associated with heredity, infection, immune disorders, trace elements and other factors. Corticosteroids and immunosuppressant were used in the routine therapy, but with greater long-term side effects and easy to relapse after drug withdrawal. The "special prescription for Betch’s disease treatment" is consisted of 12 traditional Chinese medicine herbs.It has been used in china with a history of more than 3000 years, with a very safe performance. The ingredients of the "special prescription for Betch’s disease treatment" is more complex, the mechanism of action remains to be further investigated. After long-term, large samples of clinical observation, we can make a conclude that the "special prescription for Betch’s disease treatment" is a traditional Chinese medicine does form and it is safe and reliable with confirmed curative effect, the disease was not easy to relapse, and be worth promoting in clinical practice. References: [1] Yang Guoliang, Wang Xiasheng. Modern dermatology [M]. Shanghai: Shanghai medical university press, 2000.701. [2] Du Caisu Xu Shuhua. Using Tripterygium Glycosides to cure 5 cases of Betch’s disease [J]. Changsha: magazine of contemporary physician, 1998.3 (10) :