RESPT 1213 Pharmacology page 1
1.
Unit 2 Bronchodilators Part II Corrected 2/26/08
Name:
Date:
2007
Cholinergic antagonists work on the bronchial smooth muscle by:
a. Stimulation of the Beta II receptor
b. Blocking the Beta II receptor
c. Blocking the cholinergic receptor
2.
A cholinergic antagonist will raise the HR by:
a. Stimulation of the beta I receptor on the myocardium
b. Stimulation of the Beta II receptor on the myocardium
c. Blocking the cholinergic receptor on the myocardium that should decrease the
HR
3.
A cholinergic antagonist will reduce mucus production by:
a. Stimulation of the alpha receptor on the submucosal gland
b. blocking the Beta II receptor on the submucosal gland
c. Blocking the cholinergic receptor on the submucosal gland
4.
Organophosphate poisoning is caused by:
a. Increasing the action of the acetylcholinesterase
b. Inhibition of the acetylcholinesterase
c. Causing the acetylcholine to rise because it is not being broken down
d. b and c
5.
A patient can die from organophosphate poisoning or from an overdose of
parasympathetic neurotransmitter due to:
a. Rapid HR
b. Slowed HR
c. Skeletal muscle paralysis
6.
A person who is getting intubated might get systemic atropine:
a. to raise the HR to minimize the effect of vagal reflex bradycardia
b. drop the HR to minimize the effect of vagal reflex bradycardia
7.
During CPR, a patient might get systemic atropine to:
a. Treat asystole
b. Treat pulseless electrical activity
c. Both of these
8.
Inhaled cholinergic antagonists are indicated for maintenance bronchodilation, to treat
wheezing associated with:
a. COPD
b. chronic bronchitis
c. emphysema
d. Croup
e. All of these
f. All but d
9.
Would an acutely wheezing patient do better with Albuterol MDI for rescue
bronchodilation or with inhalation of Atrovent MDI?
a. Albuterol MDI
b. Atrovent MDI
c. Doesn’t matter both are excellent rescue bronchodilators
RESPT 1213 Pharmacology page 2
10.
[Correction] A person who is going to have surgery might get systemic atropine to:
a. Minimize reflex bradycardia during intubation
b. Minimize glandular secretions during surgery
c. Both
11.
Side effects of systemic atropine include:
a. dry mouth
b. blurred vision
c. tachycardia at moderate doses
d. all of these
12.
Side effects of systemic atropine include:
a. Increased urination
b. Urinary retention
c. Complication of glaucoma by changing the shape of the iris
d. Both b and c
13.
Persons with sensitivities to soya lecithin should:
a. Get a lot of systemic atropine
b. Should avoid systemic atropine
14.
Persons with prostatic hypertrophy can suffer – with systemic atropine.
a. Increased urination
b. Urinary retention
c. Increased ocular blood pressure
15.
The brand name for ipratropium bromide is:
a. Atrovent®
b. Breathaire®
c. Spiriva®
16.
The brand name for Tiotropium Bromide is:
a. Atrovent®
b. Breathaire®
c. Spiriva®
17.
The indication for Tiotropium Bromide is:
a. prevent bedwetting
b. maintenance for COPD, chronic bronchitis and emphysema
c. rescue drug for COPD, chronic bronchitis & emphysema
d. both a and c
18.
Why is ipratropium bromide considered to be a safer inhaled drug than inhaled
atropine?
a. It has less effect on the Beta I receptor on the myocardium
b. It has poor absorption at the tissue level so less gets into the blood stream
c. Both of these
19.
The usual dose of ipratropium bromide is:
a. 500 micrograms in 2.5 ml sterile saline
b. 2.5 mg in 2.5 ml sterile saline
c. One inhalation by DPI Q day
20.
The usual dose of Tiotropium Bromide is:
a. 500 micrograms in 2.5 ml sterile saline
b. 2.5 mg in 2.5 ml sterile saline
RESPT 1213 Pharmacology page 3
c.
One inhalation by DPI Q day
21.
Combivent MDI contains these two drugs:
a. Albuterol & ipratropium bromide
b. Albuterol & racemic epinephrine
c. ipratropium bromide & salmeterol
d. the same drugs that are found in Duoneb SVN unit dose
e. a and d
f. c and d
22.
Combivent MDI is contraindicated in those persons with:
a. Peanut allergy
b. Soy food allergies
c. Both a and b
23.
The usual dose of Combivent MDI is:
a. 2 puffs BID
b. 2 puffs TID
c. 2 puff QID
24.
T/F The xanthine family of bronchodilators are oral and IV drugs.
25.
T/F Theophylline is the only bronchodilator that increases the effectiveness of the
diaphragm.
26.
T/F The xanthine family of bronchodilators work by blocking the cholinergic receptors
on the bronchial smooth muscle.
27.
The aminophyline/theophylline works by:
a. Inhibits phosphodiesterase that breaks down C-AMP
b. Blocks adenosine receptors that cause bronchospasm
c. Releases endogenous catecholamines
d. inhibition of Ca uptake
e. antagonist toward prostaglandin E2 & prostaglandin F2α
f. all of these
28.
T/F The xanthine family of bronchodilators are in the same family as caffeine and
chocolate.
29.
T/F Aminophyline and theophylline will raise the ventilatory drive.
30.
T/F Aminophyline and theophylline differ mainly by differences in route of
administration.
31.
The therapeutic serum level of theophylline for bronchodilation associated with
asthma is:
a. 5 microns
b. 5-15 micrograms
c. 10 to 12 micrograms
d. +20 micrograms
32.
The therapeutic serum level of theophylline for bronchodilation associated with COPD
is:
a. 5 microns
RESPT 1213 Pharmacology page 4
b. 5-15 micrograms
c. 10 to 12 micrograms
d. +20 micrograms
33.
The therapeutic serum level of theophylline for treatment of apnea of prematurity is:
a. 5 microns
b. 5-15 micrograms
c. 10 to 12 micrograms
d. +20 micrograms
34.
Side effects of aminophylline include:
a. Tachycardia, hypotension & cardiac arrhythmias
b. convulsions and seizures
c. nausea, vomiting, cramps, diarrhea
d. all of these
35.
Drug interactions with aminophylline that result in decreasing the available amount of
the drug include:
a. Nicotine
b. Marijuana
c. Eating charcoal-grilled foods
d. TB antibiotics
e. All of these
36.
Phenobarbital is an excellent drug to give to a patient with an aminophylline overdose
because:
a. Phenobarbital treats the seizures & convulsions associated with this drug
b. Phenobarbital decreases the amount of aminophylline in the body
c. Both
37.
Taking activated charcoal:
a. Can act as an antidote to aminophylline
b. Decreases the serum level of aminophylline
c. Increases the serum level of aminophylline
d. A and b
e. A and c
38.
Magnesium Sulfate:
a. Is given by inhalation
b. Is given by IV
c. Relaxes smooth muscles in both labor contractions and asthma
d. A and c
e. B and c