DOWNRIVER CARDIOLOGY CONSULTANTS PATIENT EDUCATION INFORMATION: RE: ENDOCARDITIS Endocarditis is a bacterial infection involving the valves or components of the heart. Generally this can occur whenever bacteria enter the bloodstream and lodge on injured areas of the heart. Usually the body’s normal defense mechanisms are adequate to destroy these bacteria. In some instances, injured areas of the heart allow greater numbers of bacteria to accumulate and the body is less successful in warding off an infection. Although endocarditis may occur in patients with normal hearts, it is unusual in comparison to those with some type of heart disease. All individuals are exposed to transient mild increases in bacteria in the blood. However, this increase in bacteria is higher following procedures that cause some type of bleeding in areas that cannot be adequately cleansed or sterilized. For instance, there may be an increase in bacteria from procedures as simple as teeth cleaning. In 2007, the American Heart Association issued new recommendations for the prevention of endocarditis. In general, these recommendations markedly reduce the number of individuals that require the use of antibiotics prior to most procedures. The prior philosophy was that antibiotics were indicated because it was “the right thing to do.” On the other hand, there had not been extensive studies that documented either the need for these antibiotics nor the fact that they were beneficial. As an example, bacteria frequently enters the bloodstream following routine daily activities such as chewing food, flossing, the use of toothpicks, brushing your teeth, and the use of water irrigation devices. Since these activities occur on almost a daily basis, there may be a higher risk during a lifetime than there is in frequent professional dental cleaning or dental work. For most patients, recommendations for antibiotics prior to routine dental work are not recommended. These new guidelines also have common sense recommendations. Maintaining good dental care to reduce gum infections and other dental problems would seem much more effective in reducing the release of bacteria into the blood than the use of infrequent antibiotics during teeth cleaning. The other concern that has arisen with the use of antibiotics prior to dental care is the development of strains of bacteria that are resistant to antibiotics. In this instance, when you truly need an antibiotic for a major infection, it may no longer have the desired benefit. In patients with infections of their bowel or urinary and bladder systems, it would be appropriate to treat the underlying infection prior to any surgical procedures that might increase the entrance of bacteria into the bloodstream. In treatment of these infections, your physician should use an antibiotic to treat the infection but also include a method that is active against the bacteria that can cause endocarditis. Usually Amoxicillin or Ampicillin is the preferred antibiotic. In the past, many cardiac conditions were felt to be susceptible to endocarditis. The new guidelines changed this to only those conditions which are higher risk of major adverse outcome from endocarditis might benefit from antibiotics prior to the procedures. 1. 2. 3. DCC, December 2007 Prosthetic cardiac valve History of prior or previous infective endocarditis Congenital heart disease (CHD) Unrepaired cyanotic CHD including shunts and conduits. Completely repaired congenital heart disease with prosthetic material or device, either placed by surgery or catheter intervention during the first six months after the procedure. (After six months, it is felt that the body has coated the material with a thin layer of protective cells) Repaired CHD with an underlying residual defect at the site or adjacent to the site of the artificial patch or device. Cardiac transplantation patients who develop cardiac valve abnormalities. 4. An antibiotic used for the prevention of endocarditis should be administered in a single dose before the procedure. If it has been forgotten it may be administered up to 2 hours after the procedure but this is not the ideal situation. Antibiotics are RECOMMENDED for patients: o Prior to all dental procedures involving cutting or manipulation of gum tissue or the tip region of the teeth or cutting or perforation of the lining of the mouth. o Surgical procedures of the lining of the lungs or throat including tonsillectomy and adenoidectomy. o Bronchoscopy only if biopsy or cutting is involved. o Any surgery on the throat, lungs, infected skin structures, or muscles that are also infected. Antibiotics that are useful for endocarditis should be part of the program for treatment when surgery is performed on infections of the bladder, urinary tract, bowel, respiratory tract or lung. Common conditions for which antibiotic prophylaxis is NOT NECESSARY: o Routine anesthetic injections through non-infected tissue o Taking dental x-rays o Placement of removable prosthodontic or orthodontic appliances o Adjustment of orthodontic appliances o Placement of orthodontic brackets o Shedding of baby teeth o Bleeding for trauma to the lips or mouth o Normal vaginal deliveries o Colonoscopy or endoscopy o Cystoscopy o TEE (transesophageal echocardiography) o Cardiac catheterization DCC, December 2007 o Intracoronary stent o Coronary artery bypass surgery SUMMARY: It is your responsibility to notify surgeons and dentists if you have any cardiac problems that would require the use of antibiotics. In general, these new recommendations limit the number of conditions that require antibiotics and also limits the number of procedures for which antibiotic protection is required. DCC, December 2007