Programme Translational Imaging Workshop by AMIE
‘From mouse to man’
Final vs 130920’
Tuesday 24, Wednesday 25, Thursday 26 and Friday 27 September,
2013
(Friday 27 long practicals)
The programme Applied Molecular Imaging at Erasmus MC (AMIE) provides a platform for
scientists interested in imaging technology and molecular imaging in general.
The aim of this 4-day workshop is to give a broad introduction into preclinical and translational
Molecular Imaging techniques and their applications in biology and medicine. This workshop is
designed for PhD students and researchers in one of the Erasmus Postgraduate Schools; PhD
students and researchers from other universities are also welcome. This workshop is being
organized for the seventh time, following upon six very successful workshops in 2008 - 2012.
The speakers from the Erasmus MC, the Leiden University Medical Centre (LUMC) and the
Technical University Delft (TU Delft) have great expertise in animal and molecular imaging.
The workshop will cover a wide array of imaging technologies, including:
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Optical imaging
X-Ray Computed Tomography (CT)
Magnetic resonance imaging (MRI)
(Multimodality) Radionuclide imaging: PET and SPECT
Ultrasound imaging
Photo dynamic diagnostics and therapy (PDT)
Raman spectroscopy
Image Analysis
Several applications in translational research will be discussed, such as multi-modality detection,
imaging of cancer, and imaging of vascular diseases. In addition to the lectures presented in
the programme, practical demonstrations on the different imaging devices will be given in the
newly realized Animal Imaging Facility, the AMIE Facility, designed to facilitate multi-modal
animal imaging. SPECT/CT (U-SPECT/CT, NanoSPECT/CT), PET (Inveon), CT (Skyscan), optical
(ICIS), and MRI (7T GE/Varian) imaging equipment are housed in a single complex.
On Friday, we offer the opportunity to the participants to do a long practical session
during a full day. Limited admittance: first come, first serve.
The total number of participants in the course is limited to 70; the total number of participants
in the demonstrations, lab visits and practical sessions on Friday is limited to 40. The latter are
based on ‘first come, first serve’. Tuition is €550 (including lunches and one dinner); however,
most participants are expected to qualify for a (partial) scholarship. See the last page for
details.
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The workshop counts for 1,25 ECTS credit points, including all lab visits, practical sessions and
self study; 1,00 ECTS without the practical session on Friday.
The location of the workshop is room Ae 4.06 (Erasmus MC). All lunches and one
dinner are included.
Registration via the Website of MolMed: www.molmed.nl.
We offer a dinner for all participants on Tuesday evening and a closing drink for all
participants on Friday afternoon. If you have any questions, please contact Frank van Vliet:
+31 (0)10 704 3518 or + 31 (0)6 5474 6408 or Joris Lenstra: +31 (0)10 703 8053 /
molmed@erasmusmc.nl.
The organizing committee,
Marion de Jong
Monique Bernsen
Hans Bosch
Jeroen Essers
Joost Haeck
Frank van Vliet
The organizers wish to thank the following for their invaluable contributions to this
workshop:
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Tuesday September 24th; room Ae 4.06
Time
09:00-09:30
09:30-09:45
09:45-10:30
10:30-10:45
10:45-11:30
11:30-12:15
12:15-13:15
12:30-13:15
13:15-14:00
14:00-14:45
14:45-15:00
15:00-15:45
15:45-16:30
16:30-17:15
17:30-…
Speaker
Title
Key words
Registration
Moderator: Marion de Jong, Dept. of Nuclear Medicine, Erasmus MC
Marion de Jong,
Welcome and short
Applied Molecular Imaging at the
Dept. of Nuclear
introduction to the
Erasmus MC (AMIE)
Medicine&Radiology, Translational Imaging
Erasmus MC
Workshop
Wout Breeman,
Radiochemistry
Tutorial: Tracer, labeling,
Dept. of Nuclear
cyclotron, generator
Medicine, Erasmus
MC
Coffee break
Mathieu Sommers,
Animal facilities and animal Applications
Dept. Animal
imaging; animal models
Facility
Marlies Goorden, TU SPECT imaging
Tutorial: Physics, instrumentation,
Delft & MILabs
and some applications
Lunch
Sponsoring session: Chu Sun Wong, Bruker; The Cryoprobe. How cool is that?
Moderator: Monique Bernsen, Dept. of Dept. of Radiology, Erasmus MC
Marleen Melis,Dept.
Radionuclide imaging
Applications: SPECT and PET,
of Nuclear Medicine
radionuclide therapy
Louise van der
Introduction to MRI
Physics & instrumentation; UltraWeerd, LUMC
high field MRI, high resolution,
phenotyping, contrast at high
field, anatomy & functionality,
molecular imaging
Coffee break
Piotr Wielopolski,
MRI
Applications: neurological (AD),
Dept. of Radiology,
cardiac (MI, atherosclerosis)
Erasmus MC
Hans Bosch &
Ultrasound imaging
Tutorial: Physics, instrumentation,
Klazina Kooiman,
and applications
Biomedical Engineering,Cardiology,
Erasmus MC
Joost Haeck, Dept.
(Multimodal) PET imaging,
Tutorial: Physics and
of Nuclear Medi(combined with MRI and
instrumentation, PET,
cine&Radiology,
CT)
radionuclides, tracer
Erasmus MC
Participants and speakers dinner offered by the Postgraduate School
MolMedRestaurant Indonesia, Rodezand 34, Rotterdam, 010-414 85 88 (10
ps.)
Wednesday September 25th; room Ae 4.06 <> room 11-12.30?
Time
09:15-10:00
10:00-10:45
Speaker
Moderator: Jeroen
Erasmus MC
Fred Verzijlbergen,
Dept. of Numclear
Medicine, Erasmus
MC
Fijs van Leeuwen
(NKI & LUMC)
Title
Key words
Essers, Depts. of Cell Biology & Genetics and Radiotherapy,
Probes for molecular
imaging
Tutorial: Basics in MI, physics and
applications
Probes: Hybrid imaging
agents for interventional
molecular imaging, a
clinical story
Applications: surgical guidance,
sentinel node, SPECT,
fluorescence, targeted peptides,
multimodal
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10:45-11:00
11:00-11:45
Coffee break
Monique Bernsen,
Multi-modality imaging
Applications: equipment, probes
Dept. of Radiology
and applications, pittfalls and
& Nuclear Medicine,
future outlook
Erasmus MC
11:45-12:30
Erik Meijering,
Image Analysis
Applications: Quantitative image
Biomedical Imaging
analysis; Multimodal image
group Rotterdam,
analysis; Image registration,
Depts. of Radiology
fusion, and visualization
& Med. Informatics,
Erasmus MC
12:30-13:30
Lunch break
12:45-13:30
Sponsoring session: PerkinElmer, Sasha Belenkov
Moderator: Monique Bernsen, Dept. of Dept. of Radiology, Erasmus MC
13:30-14:15
Erwin Waarsing,
X-Ray CT: Computed
Tutorial: physics, instrumentation,
Dept. of OrthopeTomography
and applications
dics, Erasmus MC
14:15-14:45
Kjell Laperre,
High resolution micro-CT in Applications: x-ray micro CT,
Application
biomedical applications
small animal imaging, in-vivo,
scientist, Bruker
synchronization
microCT
14:45-15:00
Coffee break
15:00-16:00
Key note speaker: Pretargeting with bispecific
Radioimmunotargeting, radioimOtto Boerman,
antibodies: from mice to
munotherapy, pretargeting,
Dept. of Nuclear
men
monoclonal antibodies, bispecific
medicine, UMCN,
antibodies, colorectal cancer,
Nijmegen
tumor-associated antigens
16:00-17:40
Coordination:
Demonstrations; lab visit
6 topics, 4 groups, each group
Jeroen Essers,
(sessions 1 & 2 of 50’
about 6 participants (name, room
Depts. of Cell
each); schedule see
nr.):
Biology & Genetics
below
 MRI (M. Bernsen, J. Haeck;
and Radiotherapy
AMIE Facility, CE building)
 CT (Erwin Waarsing, AMIE
Facility, CE building)
 SPECT/PET (M. de Jong, J. de
Swart, AMIE Facility, CE
building)
 Ultrasound (Hans Bosch, Klazina Kooiman; room Ee
23.29)
 Optical Imaging/Ivis 200
(cfd., Jeroen Essers, Yanto
Ridwan, room Ce050)
 CAVE (3-D) (A. Koning, via
corridor Ee 15.28-15.42)
Session 1 16:00 – 16:50
Group1
SPECT-PET
Group2
Optical Imaging
Group3
Ultrasound
Group4
CAVE
Session 2 16:50 – 17:40
Group1
Group2
Group3
Group4
MRI
CT
CAVE
Ultrasound
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Thursday, September 26th; room Ae 4.06
Moderator: Klazina Kooiman, Dept. of Biomedical Engineering/ Cardiology,
Erasmus MC
Time
Speaker
Title
Introduction or application;
Key words
09:15-09.45
Dominic Robinson,
Optical Diagnostics and
Applications: Physics, Optical
CODT/Dept. of
Photodynamic Therapy
Spectroscopy, Imaging, Light
Radiotherapy,
Therapy, Instrumentation and
Erasmus MC
Applications
09:45-10:30
Gerben Koning,
Intravital Imaging
Applications: intravital microscopy,
Surgical Oncology,
cancer, confocal, intratumoral, in
Erasmus MC
vivo intracellular
10:30-10:45
Coffee break
10:45-11:30
Gerben Koning,
Targeted nanocarriers for
Applications: Multifunctional lipidDept. of Surgical
imaging and therapy
nanocarriers, intravital microscoOncology, Erasmus
py, targeted nanomedicine,
MC
multimodal imaging, cancer,
inflammation
11:30-12:00
Tom Bakker Schut, Raman spectroscopy
Applications: In vivo/ex vivo tissue
CODT/Dept. of
characterization & diagnostics;
Dermatology,
physics, instrumentation and
Erasmus MC
applications
12:00-13:00
Lunch break
12:15-13:00
Sponsoring session: MILabs
Moderator: Klazina Kooiman, Erasmus MC
13.00-13:45
Eric Kaijzel, Dept.
Optical imaging
Applications: Physics of
of Genetics, LUMC
fluorescence and bioluminescence,
gene reporter constructs on cells;
instrumentation; fluorescent and
bioluminescent probes on cancer
13.45-14.35
Coordination:
Demonstrations; lab visit
6 topics, each group max. 7
Jeroen Essers,
(session 3 of 50’)
participants (see Wednesday 25
Depts. of Cell
September)
Biology & Genetics
and Radiotherapy
14:35-15:00
Coffee break
15:00-17:30
Coordination:
Demonstrations; lab visit
6 topics (see above)
Jeroen Essers
(sessions 4, 5 & 6 of 50’)
Session 3; 13:45 – 14:35
Group1
Optical Imaging
Group2
Ultrasound
Group3
SPECT-PET
Group4
MRI
Session 4; 15:00 – 15:50
Group1
Group2
Group3
Group4
Ultrasound
MRI
CT
Optical Imaging
Session 5; 15:50 – 16:40
Group1
Group2
Group3
Group4
CAVE
SPECT-PET
Optical Imaging
CT
Session 6; 16:40 – 17:30
Groep1
Groep2
Groep3
Groep4
CT
CAVE
MRI
SPECT-PET
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Friday, September 27th
Time
09:00-12:00
13:00-16:00
16:00-….
Moderator: Marion de Jong, Dept. of Nuclear Medicine, Erasmus MC
Speaker
Title
Introduction or application;
Key words
Coordination:
Demonstration with
SPECT – MRI
All day
Jeroen Essers
experiments for admitted
CT–Optical imaging All day
applicants. First come, first
Ultrasound
½ day
serve-basis. Please
subscribe during the
workshop.
Lunch break
Coordination:
Cont’d: Demonstration with SPECT – MRI
All day
Jeroen Essers
experiments for admitted
CT–Optical imaging All day
applicants. First come, first
CT – bone imaging ½ day
serve-basis. Please
subscribe during the
workshop.
Drinks offered by Postgraduate School MolMed; Ae 4.06
Attendance fees
Course tuition for non-commercial participants is € 550. Discounts are handled as followed:
 Participants from the postgraduate school MolMed get a discount of 100% (tuition =
€0).
 PhD students and Master’s students, regardless of institution, get a discount of 50%
(tuition = €275).
 Master’s students who are paying the fee from their personal budget get a discount of
75% (tuition = €137,50).
participant category
discount
full-tuition, non-commercial
tuition
0%
€
550
100%
€
0
PhD students, Master’s students (regardless of
institute)
50%
€
275
Master’s students paying the tuition from their
personal budget
75%
€
137,50
members of MolMed
The course is considered an entirety, and participants are encouraged to attend all parts of the
course. No discounts are given for participants who chose not to participate in a portion of the
course. If these financial requirements pose a problem, please contact Frank van Vliet,
managing director of the Erasmus Postgraduate School Mol Med, at: f.vanvliet@erasmusmc.nl.
Invoices
Fees should only be paid after receipt of an INVOICE. Shortly after your registration you will
receive the INVOICE by mail. Payment should be transferred to account: 43.47.01.408 /
Erasmus MC, (IBAN code bank: NL86ANBA0434701408; SWIFT code bank: ABNANL2A), with
the invoice number noted. Late registrations may also pay in cash upon arrival.
Cancellations
Cancellation is possible up to one week before the start of the Course. Later
cancellation will not be accepted, but you are allowed to send a substitute.
Commercial participants & sponsors
Companies are invited to inquire about commercial participant tuition fees and about
sponsoring.
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