Review sheet – Chapter 3 Understand that organic compounds are, by definition, carbon-based Understand why carbon with its 4 outermost electrons is unparalleled in its ability to form large, diverse molecules Understand that carbon completes its outermost shell by sharing electrons in covalent bonds Understand (and be able to identify) that methane, CH4 is one of the simplest organic compounds Know the definition of a hydrocarbon; be able to recognize an example of a hydrocarbon Understand that carbon skeletons vary in length, can be branched or unbranched, have double or single bonds, and form rings or not Be able to recognize the six functional groups vital to organic compounds: hydroxyl, carbonyl, carboxyl, amino, phosphate, and methyl Understand that subtle changes in one or more functional groups results in significant changes in the chemical properties and thus, actions of these molecules (example: testosterone and estrogen) Understand that there are 4 important organic molecules: carbohydrates, lipids, proteins and nucleic acids Understand what a polymer is, and that it consists of monomers Understand that carbohydrates, proteins and nucleic acids (and to a lesser extent lipids) are polymers Understand dehydration and hydrolysis reactions – which one builds up polymers and which one breaks them down; how? Know that a polymer and an unlinked monomer have a hydroxyl group (OH) on one end and an H atom on the other end; how does this facilitate water removal or addition? Understand that hydrolysis and dehydration reactions proceed with the help of enzymes; understand that enzymes speed up and facilitate the chemical reactions in cells Understand that carbohydrates are made up of hydrogen, oxygen, and carbon Understand that carbohydrates are made up of monosaccharides monomers Understand that monosaccharides can be linked together to form polysaccharides Know that polysaccharides contain many monosaccharides and that disaccharides contain 2 monosaccharides Understand that glucose is a monosaccharide and is produced by plants during photosynthesis and serves as the fuel for cellular work Understand that monosaccharides generally have the molecular formula that is some multiple of CH2O (ex. C6H12O6) Understand that glucose is water-soluble (hydrophilic) Be able to recognize the three disaccharides: maltose, sucrose, and lactose Understand that a dehydration reaction is required to combine monosaccharides into di- or poly-saccharides Understand that the most common types of polysaccharides are starch, glycogen, cellulose and chitin Know the fundamental differences and characteristic of starch, glycogen, cellulose and chitin Know that starch and glycogen are storage polysaccharides composed of many glucose molecules Know that cellulose and chitin are structural polysaccharides Understand the process of storing and breaking down glucose molecules in the human body (the roles of glucose, glycogen, insulin, glucagon) Understand the limitations of cellulose in the animal diet Understand that lipids include oils, fats, waxes, phospholipids and steroids; know that they contain carbon, hydrogen and nitrogen linked by nonpolar bonds Know that lipids contain twice as much energy as carbohydrates Understand what a fat is (what it is composed of) and why it is called a triglyceride Understand how dehydration reactions create a fat molecule Understand the difference between saturated and unsaturated fats; why do unsaturated fats not contain the maximum amount of hydrogen atoms?, which are solid/liquid at room temperature? What roles do triglycerides play? (storage of energy, insulation, etc) Understand what a phospholipid is; understand the nonpolar and polar components of a phospholipid Understand how a phospholipid bilayer provides a cell with a structure (membrane) that separates the outside of the cell from the inside; be able to draw a phospholipid bilayer Understand that steroids are lipids that do not contain fatty acids, but are composed of 4 carbon rings fused together Understand that cholesterol is a common steroid found in animals (not plants) Be able to recognize estrogen, cortisol, progesterone and cholesterol as steroids Understand that proteins are built up from 20 different amino acids Know that amino acids are molecules that have a carboxyl and amino group Be able to identify an example of a protein or a substance made up of proteins given in class Know why 8 of the amino acids are considered essential Understand what a peptide bond is, and that it is a covalent bond Understand that the shape of a protein determines its function Know the definition of denaturation Know and be able to describe the 4 levels of structure of a protein Know what a prion is and why it is so lethal Know what a nucleic acid is and what 2 molecules are nucleic acids (DNA and RNA) Know how RNA and DNA differ in the types of bases (DNA: A,T,C,G; RNA: A, U, C, G) Know which sugars make up RNA (ribose) and DNA (deoxyribose) Know the monomers that make up nucleic acids (nucleotides) Know that nucleotides consists of a phosphate group, a 5-Carbon sugar, and a nitrogenous base Know which nitrogenous bases pair up with each other (e.g., A and T in DNA, etc) Understand how the phosphate group of one nucleotide binds to the sugar of another during dehydration synthesis Understand the sugar-phosphate backbone and how nitrogenous bases protrude from this Understand that DNA is a double helix resulting from 2 polynucleotides wrapping around each other and held together by hydrogen bonds between their base pairs