Biology 2112: Introduction to Biology - Fall 2013 Policies and Syllabus Instructors: Lab Coordinator: Dr. Richard Waring and Dr. Rhonda Nicholson Dr. Daniel Spaeth Office Hours: For Rhonda Nicholson: (Biology, Rm 402B, 204-9547; email: rnichol@temple.edu): WF 10:0011:30 or by appointment. For Dr. Richard Waring: (Biology, Rm 307, 204-8877; email: waring@temple.edu): WF 10:0011:30 or by appointment. Dr. Waring's web page can be found at http://unix.temple.edu/~waring/. Please direct all questions about the lab to your lab instructor or see Dr. Dan Spaeth (Biology, Rm 248Q (inner hall across from the Biology Office), 204-6722; email: daniel.spaeth@temple.edu). Further contact information for laboratory instructors will be provided on Blackboard (Bb). Any student who has a need for accommodation based on the impact of a disability should contact either instructor privately to discuss the specific situation as soon as possible. Contact Disability Resources and Services at 215-204-1280. New rules at the DRS require advanced notice by several days for exam accommodations. It is the responsibility of the student (with the lecture instructor’s assistance) to adhere to the DRS schedule for registration and paperwork when requesting an exam accommodation. All requests for accommodations must be communicated to lab coordinator as well. IMPORTANT: It is necessary for this course that you obtain AccessNet and Temple email accounts (Obtain these by going to http://www.temple.edu/cs. You can also visit the Computer Services Help Desk, Rm 106, TECH Center, 12th St. & Montgomery Ave. Call 204-8000 for more information). Without an AccessNet account you will not be able to access the Blackboard site for this course. Access to this site will be explained to you at the start of the course. Exam scores are posted through the Blackboard site. Blackboard will also be used to post all the announcements pertinent to the course and the Lab. Text Excerpts from Campbell Biology by Reece, Jane B et al., 2011, Ninth Edition. Benjamin / Cummings Publishing Co., Inc., California. Available in the Bookstore as 3 options (A) the textbook with a Mastering Biology Access Code; (B) as a package which includes (1) Campbell Biology in three-hole punched, unbound format (2) Mastering Biology Code); (3) Morgan/Carter Customized Lab Manual. Item (3) is only required for the partner Introduction to Biology course, 1111. (C) Mastering Biology Access Code (comes with e-version of the textbook which is accessible for 2 years); Mastering Biology provides access to web based support material including test exercises. Course Design: The first seven weeks of this course will be taught by Dr. Nicholson. The second seven weeks will be taught by Dr. Waring. Dr. Nicholson will provide an introduction to the basic chemical and biochemical principles underlying biology. Topics include energy, solubility, macromolecules, enzymes, cells, the functions and properties of membranes, metabolism and photosynthesis. Dr. Waring will concentrate on cell communication and division, viruses, genes, DNA replication, transcription, and translation. He will also discuss basic genetic concepts and introduce topics concerning gene expression. You should read all the chapters listed. However certain subtopics (usually 1 to 2 page sections, especially in chps. 11, 13, 17, 18 & 19) will not be covered in the exams: these will be pointed out to you during lectures. Problems suggested in Dr. Nicholson’s study guides will be used in modified form on exams. Dr. Nicholson’s study guides will be posted with the associated lectures on Blackboard. You should complete each study guide within a few days of the associated lecture. Solutions to quantitative study guide questions will be posted with the study guide on Blackboard. During the second half of the semester, Dr. Waring will give two assignments relating to chapter 17 – these will count towards your lab grade. You will have one full week to do them and you should hand them in to your lab instructor in your lab session the following week. Assignment Details are available in lab. You are advised, ideally to read ahead, preferably to review current material between lectures, and minimally to keep up with the course. Previous students have stated that it is very difficult to catch up on missed materials especially because current lectures (and a Biology major in general) build on previous topics. There is too much material to cover in the week before an exam. It is your responsibility to acquire copies of assignments or "electronic" handouts on the Blackboard site. It is also your responsibility to acquire copies of lecture notes from someone in the class if you cannot attend class. We strongly discourage incompletes. However, if you must take an incomplete you need to have taken the first four lecture exams, be passing the course, have attended all the labs and submitted most of your lab assignments and reports. To receive an incomplete you need to fill out a form that is available in the Biology Department Office and have it signed by Dr. Waring or Dr. Nicholson. It is very important that you also inform Dr. Spaeth if you are taking an incomplete. Your incomplete must be made up by the end of the following Fall semester; however if you failed to complete only the final exam, you must take the make-up exam in the following Spring semester as described below with grade calculations. Failure to make up an incomplete within the designated time limit will result in your being given a zero for the work that you did not complete. The prerequisites for this course are successful completion of Chem 1031(C or better) and Chem1032 (C or better) or equivalent. You must also, either be enrolled in, or have passed Chem 2201, Organic Chemistry (C- or better). You should be able to use logarithms, exponentials and do simple algebra (Note that Math 1041 and 1042 are required for the Biology and Biochemistry majors (see undergraduate bulletin). You do not need Bio 1111 to take Bio 2112. These two courses can be taken in any order. However, you must receive a C or better in both Bio 1111 and Bio 2112 before you will be allowed to take Bio 2203 (Genetics) and Bio 3096 (Cell Structure and Function). Last day to drop (tuition refund available): Monday, September 9th. Last day to withdraw (no refund): Tuesday, October 22nd. Students who have previously withdrawn from the same course may not withdraw. Those who have already withdrawn from several other courses should check their eligibility to withdraw. With regard to repeating courses, a W grade counts as one attempt at a course. The same course may not be repeated more than once without permission of a CST and a departmental advisor. No course may be repeated more than twice. See the undergraduate bulletin for further information. Dates for Exams: Exams given by Dr. Nicholson : Exam I: Friday September 20 Exam II: Friday October 4 Exam III: Friday, October 18 Exams given by Dr. Waring: Exam VI: Monday November 4 Final Exam given by Dr. Waring will be according to Temple’s exam schedule Calculation of grade Exam I Exam II Exam III Exam IV Final Labs 13% 13% 13% 10% 26% 25% All the grades will be posted on the blackboard site. Using your blackboard account you will be able to access them as soon as they are entered into the system. Exams are closed book. Giving or receiving information during an exam is a violation of the Temple University Student Code and will result, at a minimum, in a Failing grade. No programmable calculators will be permitted. Translators are not permitted. The use of cell phones will not be permitted in exams (or during lectures). In both Dr. Nicholson’s and Dr. Waring’s parts of the course, you will be examined primarily on material covered in both the textbook and the lectures and on topics which were discussed in depth in lectures but not in the textbook. Questions may include material you were specifically directed to read in order to cover sections only summarized in the lecture. Dr. Nicholson will administer examinations 1-3. The format of examinations 1-3 will be multiple choice, short answer, and computation. Dr. Waring will administer examination 4 (multiple choice) and the final examination. The final exam will contain a variety of styles of questions including problems, short paragraph and multiple choice questions. Examinations will not be returned to you. Examination scores will be posted on Blackboard. You are welcome to review your test during office hours or by appointment. All queries concerning the grading of midterm exams must be presented no later than two weeks after scores are posted on Blackboard. All queries concerning the grading of the final exam must be directed to Dr. Waring in writing no later than two weeks after the start of the following spring semester. Dr. Nicholson is the final arbiter for the first three midterms and Dr. Waring for the last midterm and final exam. Tests must be taken during their scheduled time. If you are absent from an examination due to a medical emergency, a letter explaining the circumstances, signed and dated by a physician (unrelated to the student), must be submitted to Dr. Nicholson/ Dr. Waring as soon as it is reasonably possible. If you miss an examination and the appropriate instructor is not notified within 72 hours, you will receive a zero for that examination. A make-up examination will only be administered in the event that proper documentation is provided to Dr. Nicholson/ Dr. Waring. If you miss exam 4 for an acceptable reason, you will receive a weighted average of all the other exams. If you miss the final, you must take a make-up exam by the end of the third week of the following semester. All make-ups are at the discretion of the lecture instructor. Academic Code of Conduct Although you will conduct lab experiments with a group of people, and discuss your results with them, the interpretation and conclusion with supporting argument should be your work, your thoughts, in your own words. All individual assignments in lab are checked for plagiarism using the on- line Safe Assign service available through Blackboard. Review the Temple University Policy on Plagiarism and Academic Cheating: http://www.temple.edu/bulletin/Responsibilities_rights/responsibilities/responsibilities.shtm You are responsible for following this policy for all assignments, tests and exams; students who do not will be penalized. The penalty will vary with the nature of the offense, and will involve, as necessary, the lab coordinator and lecture instructors, the department, and the college. Fall 2013, Biology 2112 Lab Syllabus Overview of schedule of labs and lab manual chapters. For details of lab exercises and assignments see lab syllabus Lab Date Protocol Lab Subject and Chapter No labs week of 8/26 (first week of the Fall semester) No labs Labor Day Monday (9/2) 1 2 9/2 Y Introduction, Safety & Measurement (Intro to graphing and data presentation on the computer) Note canceled Monday labs must be made up during the first week in another lab section. 9/9 Y Dilutions & Spectrophotometer Techniques Last day to drop class Monday September 9th 3 9/16 Y pH and Buffers 4 9/23 Y Organic Molecules (Enzyme Protocol write-up) 5 9/30 N Computer lab part 1 with RasMol (part 2 done outside of lab) 6 10/7 Y Enzyme Action 7 10/14 Y Photosynthesis 8 10/21 Y Cells (microscope and measurement) Tuesday October 22nd is last day to withdraw 9 10/28 Y DNA (I) Purification 10 11/4 Y DNA (II) Analysis 11 11/11 Y DNA (III) – Mitosis, Meiosis & Mendel 12 11/18 No labs 11/25 Final Lab Exam / Administration THANKSGIVING WEEK NOTE: Students in labs that meet Monday (9/2) are required to attend a lab later in the week. The letter Y in the Protocol column indicates that that a written protocol is required. INTRODUCTION TO BIOLOGY 2112 FALL 2013 MWF 9:00 – 9:50 Anderson 17 Instructors: Richard Waring & Rhonda Nicholson Lab Coordinator: Daniel Spaeth Class Lecture 1 2 3 1 2 3 4 4 5 5 6 6 7 7 8 8 9 9 10 11 12 10 13 14 15 11 12 13 16 14 17 18 19 15 16 20 17 21 18 22 23 19 Date Topic First Part by Dr. Nicholson Aug. 26 W 28 F 30 6 M Sep. 2 W4 Introduction , Chemical Bonds Properties of Water I Properties of Water II Labor day - No Class Carbon Chemistry (Functional Groups) F 6 Macromolecules I (Carbohydrates and Lipids) M Sep. 9 Macromolecules II (Proteins) W 11 Macromolecules III (Nucleic Acids) F 13 Thermodynamics I (Laws of Thermodynamics) M Sep. 16 Thermodynamics II (Energy and Enzymes) W 18 Neida Perez Guest Lecture F 20 Exam I (Lectures 1-9) M Sep. 23 Enzyme Kinetics I W 25 Enzyme Kinetics II F 27 pH and Buffers M 30 Cells I (Endomembrane System) Oct. W 2 Cells II (Cytoskeleton and Extracellular Matrix) F 4 Exam II (Lectures 10-14) M Oct. 7 Membranes W 9 Cellular Respiration I Glycolysis and the Citric Acid Cycle) F 11 Cellular Respiration II (Oxidative phosphorylation) M Oct. 14 Photosynthesis I W 16 Photosynthesis II F 18 Exam III (Lectures 15-19) Chapter Lab Schedule 2 3 3 No labs No labs No labs 4 Lab 1: Safety & Measurement Lab 1 5 5 5* Lab 2: Spectrophotometer Lab 2 8* Lab 2 8* Lab 3: pH & buffers 6 Lab 3 Lab 3 Lab 4: Organic molecules Lab 4 Lab 4 Lab 5: Computer labs Macromolecules Lab 5 7 9 Lab 5 Lab 6: Enzyme action Lab 6 9 Lab 6 10 Lab 7: Photosynthesis 10 Lab 7 Lab 7 * * * 6 Second Part by Dr. Waring Cell communication (pp 206217; 219-220; 223-225) Cell cycle & cell division (pp 228-237; 242-243) DNA replication (pp 305-312) DNA replication (misc. pp 312318; 320-322) 24 20 M Oct. 21 25 21 W 23 26 27 22 23 F 25 M 28 28 29 30 24 25 31 26 32 33 27 28 F 8 Gene organization; Mutations M Nov. 11 Sexual life cycle; Meiosis 17 13 34 35 36 29 30 31 W 13 Meiosis F 15 Mendelian genetics M Nov. 18 Mendelian genetics 13 14 14 37 32 15 38 39 40 33 34 35 W 20 Chromosomes; Sex linkage (286-91; 297-300) F 22 Viruses M Nov. 25 Viruses W 27 Prokaryote gene expression (pp 351-355) F Nov. 29 Thanksgiving Break-No class M Dec. 2 Eukaryotic gene expression (pp 356-59; 360-69 misc.) W 4 Cancer (pp 373-377) & Review F 6 Study Day – Tentative Review Session W Dec. 11 Final Exam 8.00 – 10.00am (Chp. 17, 13, 14, 15, 18, 19) Lab 10 Lab 11: Mitosis & Meiosis Lab 11 Lab 11 Lab 12: Final Review Lab 12 19 19 18 Lab 12 No Labs No Labs 18 No Labs No Labs 18 No Labs 41 36 42 37 W Oct. 30 Genes F Nov. 1 Transcription M Nov. 4 Exam IV (Chp. 11, 12 & 16) W 6 Protein synthesis 11 12 16 16 17 17 17 * Supplementary notes for lectures 7 -12 will be provided on Blackboard. Lab 8: Cells Lab 8 Lab 8 Lab 9: DNA Part I Extraction Lab 9 Lab 9 Lab 10: DNA Part II Analysis Lab 10