Job Description Job title: Technical Laboratory Coordinator Department/School: Biology and Biochemistry Grade: 6 Location: Claverton Down Campus, 4 South Job purpose The principal role of the lab technician will be to map the Hsp90 kinase interactome using state-of-the art proteomic and genomic tools now available in the leading fungal pathogen of humans Candida albicans. Additionally, the lab technician will provide technical and experimental support to other lab members. Hence, the lab technician will be asked to grow and maintain mutant libraries as well as prepare cells or DNA for quantitative analyses, such as microarrays, next gen sequencing, and mass spectrometry. The technician will also be expected to assist in the ordering of lab supplies and equipment and will have the opportunity to contribute to the supervision of project and Masters students. They will also oversee compliance with Good Laboratory Practise and Good Microbiology Practise activities throughout the lab. Reports to: Principal Investigator (PI): Dr Stephanie Diezmann Staff management responsibility None, although may be required to assist with supervision of other staff e.g. technical staff or supervision of visiting scientists /doctoral students. Main duties and responsibilities 1 Assisting with genomic and proteomic screens of yeast mutant libraries The lab technician will conduct a chemical genomic and proteomic screen of yeast mutant libraries as instructed by the PI. This will include culturing of mutant libraries, preparation of cells or DNA for quantitative analyses, and sample preparation for mass spectrometry. 2 Procurement of equipment and consumables The technician will provide a weekly check on resources and consumables of the lab and re-order as required. The technician will furthermore keep copies of requisition forms in date order and available for consultation and pursue delayed or overdue orders. 3 Contribute to the production of research reports and publications The laboratory technician will be asked to provide data generated in chemical Human Resources Page 1 17/02/2016 4 5 6 7 8 9 10 genomic screens in a way so that they can be analysed by the PI and collaborators. The technician will furthermore be included in the paper revision and editing process. Cryo culture maintenance The technician will be required to maintain and manage the lab’s cryo collection, which includes deep frozen mutant libraries as well as culture collections of yeast, bacteria and nematode strains. Assist with supervising student projects The technician will be asked to provide basic microbiological and molecular biological training to project and Masters students. Provide technical support This includes the preparation of media and solutions for microbiology and yeast molecular biology. Additional duties Any other duties as is required for the project as for example participate in site visit by funder Health and Safety The technician will ensure compliance with Good Laboratory Practise (GLP) and Good Microbiological Practise (GMP) activities in the molecular research laboratory and that they all are carried out safely. Keep records of maintenance and safety checks on items of equipment. Provide and collate risk assessments forms and ensure records are kept up to date in molecular research laboratories. Be expected to enforce protocol adherence for waste disposal. Liaise with relevant Department and University Safety personnel as and when necessary. Co-ordination of specialist waste-disposal activities and removals The technician will help identify segregate and record any special hazardous items of waste for inclusion in the twice-yearly “specials” disposal. They will instruct new PGR students and other laboratory workers on correct safe waste storage and disposal procedures in relevant laboratories. Records and recording information The technician will make, and keep safely, adequate and suitable records of all monitoring activities. The records will be updated in a timely manner and kept in an orderly fashion. The technician will be expected to make and collate Risk assessment forms related to teaching procedures and ensure researchers do the same. Special conditions Comply with the University of Bath Quality Assurance Codes of Practice 9 & 29 where applicable. Human Resources Page 2 17/02/2016 Person Specification Criteria Essential Desirable Assessed by A/F Qualifications Degree in Molecular Biology or Microbiology or Biochemistry or a relevant equivalent √ √ √ Postgraduate level qualification I/T R √ √ Experience/Knowledge Relevant work experience as a laboratory technician. √ √ Demonstrates depth and breadth of specialist knowledge of microbiology/molecular biology to effectively contribute to the research programme Demonstrates awareness of latest developments in the field of research Extensive knowledge of technical issues in laboratory-based science Knowledge of health and safety practises in laboratories Skills √ Ability to organise own workload, with guidance from senior colleagues if required Ability to handle and manipulate yeast mutant libraries √ √ √ √ Excellent verbal, interpersonal and written communication skills √ Ability to manage others √ √ Competent IT skills √ √ √ √ √ √ √ √ √ √ √ √ √ √ √ Attributes Innovation and developing creative solutions Enthusiasm and self-motivation √ √ √ √ Tenacity – working to achieve own objectives and overcoming obstacles An effective team worker √ √ √ √ Code: A/F – Application form, I/T – Interview/Test, R - References Human Resources Page 3 √ 17/02/2016