INFORMATION FOR OOCYTE DONORS ISO certified 9001:2008 Information leaflet 1 CONTACT NUMBERS .................................................................... 2 2 OPENING HOURS ........................................................................ 2 3 BACKGROUND ............................................................................ 3 4 DONORS (THOSE WOMEN DONATING EGGS) ....................................... 3 5 DRUGS .................................................................................... 3 6 EGG RECOVERY........................................................................... 4 7 RISKS OF DRUGS/TREATMENT ........................................................ 4 8 COUNSELLING ........................................................................... 5 9 HFEA REGISTER ......................................................................... 6 10 CONSENT FORMS ....................................................................... 7 11 EXPENSES ................................................................................ 7 12 WHAT NEXT, IF YOU ARE INTERESTED? ........................................... 7 M Rajkhowa/E Lowe, August 2006 Revision: 09 Reviewed by A McConnell: February 2014 Due for review: February 2015 Authorised QM A McConnell D:\106744104.doc PL022 © 2006, ACU Dundee – all rights reserved Page 1 of 7 INFORMATION FOR OOCYTE DONORS Information leaflet 1 CONTACT NUMBERS Ward 35 01382 633835 (ansaphone outwith 8.00 am – 5 pm) Anne McConnell 01382 632111 (ansaphone outwith 8.00 am – 5.30 pm) Email anne.mcconnell@nhs.net Appointments secretary 01382 496475 (8.45 am – 4.45 pm) Emergency calls for medical staff outwith 8.00 am – 5 pm: Mobile ‘phone 07774 694765. If there is no reply from this number, you should contact the hospital switchboard (01382 660111) who will contact one of the consultant staff for you. 2 OPENING HOURS The Unit is open; 8 am to 5 pm Monday – Friday 8 am – 12 noon, Saturday and Sunday M Rajkhowa/E Lowe, August 2006 Revision: 09 Reviewed by A McConnell: February 2014 Due for review: February 2015 Authorised QM A McConnell D:\106744104.doc PL022 © 2006, ACU Dundee – all rights reserved Page 2 of 7 INFORMATION FOR OOCYTE DONORS Information leaflet DONOR OOCYTE IVF 3 BACKGROUND Primary or premature ovarian failure has been estimated to occur in approximately 1% of women. For such women their only hope of a pregnancy lies in the use of eggs donated by a healthy female volunteer. The same technique may also apply to women whose ovaries have been removed or where she is at risk of passing on some genetic disorder. 4 DONORS (THOSE WOMEN DONATING EGGS) Healthy female volunteers are carefully selected and counselled. Some of these volunteers approach the clinic directly wishing to donate eggs, while others after further discussion agree to take part in an egg share programme. All donors are screened for certain transmittable diseases such as HIV prior to being accepted on to the programme, but it is emphasised that this is not a guarantee that the patient is free of disease, which could in theory only become apparent after the screening process. The risk of this is very small indeed. The physical characteristics of the donors are recorded. 5 DRUGS The donors undertake to use certain drugs including a series of injections to ensure the development of more than one egg; The drugs most commonly used in treatment cycles are: 1. Suprecur - a nasal spray that suppresses the hormones controlling the ovary. This is referred to as downregulation and a scan will be carried out to confirm this has happened M Rajkhowa/E Lowe, August 2006 Revision: 09 Reviewed by A McConnell: February 2014 Due for review: February 2015 Authorised QM A McConnell D:\106744104.doc PL022 © 2006, ACU Dundee – all rights reserved Page 3 of 7 INFORMATION FOR OOCYTE DONORS Information leaflet before starting injections of Menopur/Gonal F to stimulate the ovaries. Suprecur is continued while you are having the injections. 2. Menopur/Gonal F - an injection that stimulates the ovaries. During stimulation, careful ultrasound monitoring is necessary to assess the response of the ovaries by measuring the number and size of the follicles. When the follicles, which should each contain an egg, are the correct size you will be given another drug; 3. HCG - an injection which brings about final maturation of the eggs. 6 EGG RECOVERY This is done using a vaginal ultrasound probe to guide a needle into each ovary. The fluid in each follicle is then aspirated until oocytes are obtained. This is all done under a light sedation and we have an anaesthetist present at all egg recoveries. You will be able to go home an hour or so after egg recovery. 7 RISKS OF DRUGS/TREATMENT It is important to understand that few forms of medical treatment are entirely without risk. The stimulation drugs can occasionally lead to over-stimulation and formation of cysts which are temporary. In about 5% of all cases, patients over-respond to the drugs with a condition called Ovarian Hyperstimulation Syndrome. This usually settles without any specific measures but can very occasionally become severe with very serious risks to your health. Should you at any time feel that you have abdominal distension, pain, nausea or shortage of breath, then this could indicate that you have developed this problem and you should be in contact with us directly or with your own general practitioner, and do let him/her know that you are aware of the risk. M Rajkhowa/E Lowe, August 2006 Revision: 09 Reviewed by A McConnell: February 2014 Due for review: February 2015 Authorised QM A McConnell D:\106744104.doc PL022 © 2006, ACU Dundee – all rights reserved Page 4 of 7 INFORMATION FOR OOCYTE DONORS Information leaflet You can contact the Unit by telephoning the following:/ During office hours: Out of hours: 01382 633835 Ward 35 01382 632111 Anne McConnell – Business Manager 01382 660111 Ninewells main switchboard 07774 694765 Mobile 01382 660111 Ninewells main switchboard - ask to speak to Dr Kay, Dr Kini, Dr Martins da Silva or Dr Patravali, failing that, to the Duty Gynae. Registrar The technique of egg recovery could inadvertently damage organs close to the ovaries, such as blood vessels, bowel or bladder. These complications are very rare but it is only right that you should be aware of them. Bleeding or infection can also occur but are usually easily managed. 8 COUNSELLING Patients who are interested in being oocyte donors should note that we have an infertility counsellor who is independent of the infertility unit, and who will be pleased to talk with you. Her name is Mrs Anne Chien and appointments can be made by contacting the appointments secretary on (01382) 496475. Implications counselling will be organised for patients who are considering treatment which involves either donating (including sharing) or using donated eggs, sperm or embryos and also for those considering surrogacy. Implications counselling enables you to consider your thoughts and feelings about the complex emotional, practical and ethical issues around such M Rajkhowa/E Lowe, August 2006 Revision: 09 Reviewed by A McConnell: February 2014 Due for review: February 2015 Authorised QM A McConnell D:\106744104.doc PL022 © 2006, ACU Dundee – all rights reserved Page 5 of 7 INFORMATION FOR OOCYTE DONORS Information leaflet treatment in a supportive way. You will be encouraged to consider how you might manage the information around donation or surrogacy and how that might impact on yourselves, any child born as a result and on others involved in your treatment. Each counselling session lasts around an hour and your counsellor can help you to decide about further appointments. This counselling is not an assessment, it is to help you make a fully informed decision about your treatment. 9 HFEA REGISTER The Human Fertilisation and Embryology Authority (HFEA) keeps a confidential register of information about donors, patients and treatments. This register was set up on 1st August 1991 and therefore contains information concerning children conceived from licensed treatments from that date onwards. As from the year 2008, people aged 16+ (if contemplating marriage) or 18, who ask the HFEA, will be told whether or not they were born as a result of licensed assisted conception treatment, and if so, whether they are related to the person they want to marry. Until 2005, donors could choose to remain anonymous and, although they had to give identifying details for the HFEA register, these remained confidential. However, on 1st April 2005, the law changed to allow people conceived through donation to find out who the donor was, once they reach the age of 18; these changes only apply automatically to donations made after 1st April 2005. Please refer to the enclosed information leaflet ‘What you need to know about donating sperm, eggs or embryos’, produced by the HFEA. 10 CONSENT FORMS M Rajkhowa/E Lowe, August 2006 Revision: 09 Reviewed by A McConnell: February 2014 Due for review: February 2015 Authorised QM A McConnell D:\106744104.doc PL022 © 2006, ACU Dundee – all rights reserved Page 6 of 7 INFORMATION FOR OOCYTE DONORS Information leaflet We will ask you to complete consent forms which are required under the Human Fertilisation and Embryology Act, 1990. These forms give your authorisation for the use of your eggs and storage of any embryos created by your eggs. You are entitled to withdraw consent at any time up to the time of transfer of any embryos. 11 EXPENSES Egg donors can be compensated £750 (this includes expenses) for a cycle of treatment. This will be paid at the end of your treatment cycle. 12 WHAT NEXT, IF YOU ARE INTERESTED? If you would be interested in being a donor, or hearing more about it, then the next step would be to have a talk with one of the medical staff of the Assisted Conception Unit. Anne McConnell is the business manager and her telephone number is 01382 632111. She would be pleased to set up an appointment for you. M Rajkhowa/E Lowe, August 2006 Revision: 09 Reviewed by A McConnell: February 2014 Due for review: February 2015 Authorised QM A McConnell D:\106744104.doc PL022 © 2006, ACU Dundee – all rights reserved Page 7 of 7