Genentech, Inc. Ticker: Sector: Industry: Employees: DNA Healthcare Biotechnology 9,500 Analyst Recommendation I. Screening Moderate Buy Results of Screener Stock screener provided by Yahoo Finance was used to identify potential investment opportunities for the Mizzou Investment Fund. The screener returned 2 results Genentech and Gilead Sciences. After a brief overview of the two companies, Genentech was selected for further research primarily for its higher earnings growth estimate for the next year, lower debt to equity ratio and a lower beta. Quantity: 20 shares Stop-Loss: $61.00 Take Profits: $100.00 Pricing Closing Price: 52-Week High: 52-Week Low: $ 81.59 (11/10/06) $ 100.20 (12/06/05) $ 75.58 (05/02/06) Market Data & Valuation Market Cap: 86 billion Diluted EPS: $1.73 P/E: 47 Dividends: Div. Yield: Payout Ratio: na na na Profitability & Effectiveness ROA: 16.85% ROE: 26.54% Gross Margin: 84.70% Net Profit Margin: 23.83% Financial Condition Debt/Equity: 0.24 Current Ratio: 2.72 Quick Ratio: 2.13 Screener Parameters A complete list of parameters used in the screener is provided in the Exhibit A. The screener parameters were applied to the biotechnology industry to increase the Fund’s exposure to healthcare industry. Products developed by biotechnology companies have gradually emerged as an important (and sometimes the only) alternative for treatment of severe illnesses. Large cap criterion was used to identify companies with a demonstrated ability to develop commercially feasible products. II. The Firm and its Market Company Profile Genentech, Inc. is a biotechnology company that discovers, develops, manufactures and commercializes biotherapeutics A company criteria willGenentech be a valuable for significantmeeting unmet these medical needs. addition to the Mizzou Investment Fund and it will be manufactures and commercializes multiple biotechnology consistentand with the fund’s overall objectives. products, receives royalties from companies that are licensed to market products based on its technology. Considered the founder of the biotechnology industry, Genentech has been delivering on the promise of biotechnology for almost 30 years, using human genetic Zaza Tugushi information. Today, Genentech is among the world's leading ztgw3@mizzou.edu biotech companies, with multiple products on the market for serious or life-threatening medical conditions and over 40 projects in the pipeline. The company is the leading provider of anti-tumor therapeutics in the United States. AVASTIN is its best known product used to treat various types of cancer including colon and some forms of lung cancer. LUCENTIS is designated for the treatment of 1 neovascular age-related macular degeneration, the leading cause of blindness in people over the age of 55. Market Position and Competition Genentech has a strong market position and is a leader in a biotechnology industry. Genentech already introduced several successful products. These are Avastin, Herceptin, Rituxan, Tarceva, and Xolair. The Company has 40 new drugs in the pipeline in the various stages of development and the FDA approval. The Company aggressively pursues the FDA approval to use some of its existing drugs for treatment of broader range of certain deceases. For example, Avastin is used primarily to treat colon cancer and Genentech asked the FDA to use the same drug for treating certain types of breast cancer. Such approvals would boost the current sales of Avastin and other drugs significantly. The FDA approval for an extended use of Avastin is expected by the middle of 2007. Competitors of Genentech include number of companies in the healthcare industry. Yahoo competitor comparison table falls short of comparing relative companies and therefore is not included in this section. Major competitors of Genentech are biotechnology companies such Amgen (the 2nd largest biotechnology company after Genentech), Gilead Sciences, Biogen Idec and others. However, traditional pharmaceutical companies such as Pfizer, Bristol-Myers Squibb, Novo Nordisk, GlaxoSmithKline, Novartis and others are also competing with Genentech. But the business model of latter and the nature of their products are significantly different and do not compete directly with the products of Genentech. III. Economic and Industry Environment Biotechnology stocks had a strong start in 2006 but by mid-May gave back the gains achieved in the previous six months. However, earnings prospects provide reasons for optimism. The Value Line survey suggests that new products and regulatory approvals should keep sales on a steep incline resulting in improved margins. The Value Line predicts slightly lower margins for 2006 as a result of booking stock option expenses for the first time and larger R&D investments by biotech companies. This is cited as a major reason for avoiding heavy investments in the biotechnology sector at this time. Still, the biotechnology industry offers lucrative long-term returns. The industry operating and profits margins are outstanding and more importantly are expected to increase in the next several years. According to the Value Line estimates, sales in the industry will increase 42% from 2005 to 2007. Revenues of Genentech are expected to increase by 67% over the same period of time. While these estimates should be treated cautiously Genentech is expected to outperform the industry on every attribute listed in the table. As with the most industries, performance of Biotechnology industry is tied to the performance of the overall economy. Genentech performance, fueled by the regulatory approvals of its major drugs, from the mid-2003 has been phenomenal. In recent months the Company stock price has 2 been lagging behind the performance of the Biotechnology industry and overall stock market but its long-term return is still well above the industry and market returns. It seems that the biotechnology industry is gaining an upward momentum following a year of sluggish performance. 3-month and 6-month returns are once again above those of total U.S. market index. IV. Valuation First step in valuation of Genentech was to calculate appropriate discount rate. The discount rate was calculating using CAPM formula. Discount Rate = Risk-free Rate + Beta (Market Return – Risk-free Rate) Beta = 0.4515 (source: Asset Detail File) Beta = 0.3100 (source: Yahoo Finance) Beta = 0.9900 (source: MSN Money, Zack’s and Reuters) Market Return = 8.74% (obtained from the Investment Fund Management Asset Detail file as of 11/ 7/ 2006) Market Risk Premium = 8.74% - 4.586% = 4.154% 10-Year T-Bond Rate = 4.586% (11/07/06) Discount Rate = 4.586% + 0.31 x 4.154% = 5.87% (using Beta from Yahoo Finance) Discount Rate = 4.586% + 0.4515 x 4.154% = 6.46% (using Beta from Asset Detail File) Discount Rate = 4.586% + 0.99 x 4.154% = 8.70% (using Beta from MSN Money) The discount rate seems somewhat unrealistic considering inherited risks of biotechnology sector. The main reason for the low discount rate is the low beta. The discount rate used in the valuation models will be calculated using the higher beta of 0.99 to produce conservative estimates. Genentech does not pay dividends, thus rendering all dividend discount models useless. a) Owners’ Earning Valuation Model Net Income, Depreciation and Capital Expenditures were calculated using the financial data from the last four quarters. Since the fiscal year is approaching its end, annual data from previous year would be outdated to produce accurate estimates. The 1st stage growth rate is 23%, revenue growth rate in the next 5 years estimated by Value Line. The 2nd stage growth was assumed to be 5%, which is 20% of the high growth stage, producing an intrinsic value of 150.79 per share. The current price of Genentech is $81.59 which is 45% below the estimate intrinsic value. The details of the model are provided in the Exhibit B. 3 The table displays the sensitivity of the intrinsic value of the stock to change in the 2nd stage growth rate. b) Discounted Cash Flow (DCF) Valuation Model (Damodaran) The second valuation model was used to evaluate the accuracy of the Owner Earnings model taking into considerations additional factors. First, various growth rates were assigned weights. The 1st and 2nd stage growth rates are the same ones used in the previous valuation model to produce comparable results. 63.08% (Earnings per Share growth – 5 years) 23.00% (Earnings growth – Value Line) 10.76% (Net Income, Equity, Tax Rate) Historical Growth Rate: 20% Outside Prediction of Growth: 30% Fundamental Prediction of Growth: 50% The result of the valuation is $89.19 per share, which is about 10% above the current stock price. The complete output of the model is provided in the Exhibit C. V. Financial Analysis Exhibit D: Income Statement. Income Statement looks very good. Net Profit margin has improved over the past 5 years and reached 23% in 2006. The improvement in the Net Profit margins derives from an improvement in operating margins. The Company does an outstanding job of keeping its costs down while increasing the revenues. Cost of Goods sold has decreased from 17% in 2001 to 13% in 2006. Exhibit E: Balance Sheet. Balance Sheet of Genentech looks solid. Most of the items on the statement are increasing slowly without major irregularities. Change in Cash in 2005 has increased to 10% of total assets from usual 3% to 6%. It is a result of long-term debt issued by Genentech in 2005 for capital expenditures. In 2006, cash has decreased to its usual proportion of total assets. As a result of increase in long-term debt, the capital structure changed producing higher total debt to equity ratio. Accumulated deficit account has been decreasing and is at its lowest levels in the last 6 years. Exhibit F: Cash Flows. Analysis of cash flows produces mixed signals. On one hand, cash flows from operating activities have been increasing and are already higher (in just three quarters of 2006) than the total operating cash flows in 2005. Cash flows from financing activities increased primarily as a result of heavy capital expenditures. Cash flows from financing activities alternate between negative and positive figures. The biggest concern is the lack of consistency in the Net Change in cash. The total change in cash has been negative in three out of last 5 years. Year-to-date change in Net Cash is also negative. VI. Other Considerations Corporate Culture In October 2006, Genentech was named by Science magazine as the “top employer and most admired company” in the biotechnology and pharmaceutical industries. The company has placed first in each of the five years that Science has carried out this survey. The survey identifies the companies with the best reputations as employers based on whether they treat their employees 4 with “respect and whether their work-culture values align with employees' personal values.” The importance of content workforce cannot be exaggerated. Although, employee satisfaction is not directly reflected on financial statements, ultimately it improves the bottom line by retaining talented scientists in the organization as well as by attracting new ones. Risks Many risk factors associated with performance of Genentech are similar to those facing drug manufacturers in general. One of the major issues is the delay and negative ruling on patents by the Food and Drug Administration. Other risks involved are: Disappointing product sales (Avastin in particular) New competition Pipeline setbacks Potential manufacturing constraints Genentech is determined to reduce these risks. In particular, the Company increased its capital expenditures to avoid the possibility of manufacturing constraints. If some of its products are approved for treatment of broader range of cancer (Avastin, Herceptin), the boost in demand for these products will result in manufacturing constraints. Analyst Ratings The number of analysts following Genentech has recently increased from 30 to 35. BUY and HOLD recommendations have not changed in the last three months. However, STRONG BUY recommendation has increased from 7 to 13. This increase is a result of opinion of analysts who initiated the coverage of Genentech. The 1-year target price for Genentech varies from $95.31 to $105 per share. The Value Line estimate for 2009-11 ranges between $150 (high end) and $100 (low end) per share by 2009-11. S&P 500 Stock Report rates Genentech as Strong Buy. VI. Analyst Recommendation Based on the research, Genentech is a good buy and the recommendation is MODERATE BUY. Despite the excellent earnings potential in the coming years, there are still some factors that prevent recommending STRONG BUY. The Company has a high P/E ratio indicating the possibility of overvalued stock price. Valuation models do not support this notion but the stock price has been on a steep rise. In addition, very high P/E ratio may not be appropriate for the portfolio of Mizzou Investment Fund. Availability of free cash is final issue in recommending STRONG BUY. 5 As a final thought, the Fund lacks the exposure to the healthcare industry. The long-term outlook of this industry is strong and the sooner the Fund positions itself in the sector the higher the possibility of above-the-average returns. Considering the factors discussed above, I recommend buying 20 shares of Genentech, 2% of total portfolio value, for limited exposure to the healthcare industry. Recommended stop-loss is $69 or 15% below the current market price to limit downside risk. Recommended target price for taking profits is $100.00, a 52-week high, for a 22.50% gain. Setting a determined profit objective will resolve a hesitation to take the profits off the table. Sources MSN Money Reuters S&P 500 Stock Report Value Line Wall Street Journal Yahoo Finance Zack’s Disclaimer: This analysis does not necessarily reflect the beliefs of the University of MissouriColumbia or the College of Business. The insights and opinions are of the students of Investment Funds Management and should not be used in personal investment decisions. The University of Missouri and the author of this analysis take no responsibility for the validity of the valuation and analysis. 6 Exhibit A: Screener Criteria 7 Exhibit B: Owners’ Earning Valuation Model 8 Exhibit C: Discounted Cash Flow Valuation Model 9 Exhibit D: Income Statement 10 Exhibit E: Balance Sheet 11 Exhibit F: Statement of Cash Flows 12