Enrich Your Memory With Vitamins, Minerals, Herbs & Supplements by Ron White Forward As a memory expert I am always on the lookout for ways to help people improve their memory. Our memory function is based on the condition of our brain. Although we often take it for granted, our brain is vital to everything we do - from walking, talking and breathing, to making decisions and performing complex math. If our brains are not in the best condition our memory will not be either, so it is important to nourish both our bodies and our minds at the same time. Many people are concerned that as they age their memories are not what they once were. They seem to forget that, even when they were younger they had moments where they forgot things, and their memories were not so great. A bad memory is not just a matter of aging, but a combination of a number of conditions that are vital to keep the brain muscle working properly - such as proper exercise, nutrition, environmental factors, hydration, medical condition and usage. Young people are just as prone to memory problems as older people due to poor habits in learning, studying, listening and concentrating. We are able to improve our memories through different techniques and lifestyle changes, and these adaptations can also have an effect on how their brains are able to react to the chemical changes that come with age. Many studies show that early intervention in the way we take care of our bodies can have a positive effect on how our brain ages, and can even stall or stop the onset of dementia and memory problems later in life. Currently, approximately 10 million Americans develop Alzheimer’s disease - the most common form of dementia. Experts believe this number will increase in the next few years. By taking early control of what we do with our bodies, and how we nourish our brains, we may be able to turn these figures around. As a matter of fact, if we are able to take advantage of new discoveries in brain foods, exercise and brain techniques that would delay the onset of dementia by just one year there would be approximately 210,000 fewer people with Alzheimer’s disease 10 years from now. This book is devoted to vitamins, herbs and supplements that are natural substances the body uses to enhance brain function and improve memory. By adding a combination of these natural enhancers to your regular diet, in addition to implementing brain exercise, memory techniques, and physical activity, you are in a great position to fight off most of any problems you will have with your memory. This list is not all-inclusive and there could be a number of other factors (environment, diet, disease) that could be the root cause of your inability to remember something. However, starting with a few supplements may help you remember where you left your car keys! 2 The information contained in this article is for educational purposes only and is not intended to medically diagnose, treat or cure any disease. Consult a health care practitioner before beginning any health care program. *All rights reserved worldwide. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without the written permission of the publisher, except where permitted by law. All photos inserted in this ebook have been researched as being available for public domain. 3 Table of Contents Chapter 1: Natural Memory Enhancers Work For All Ages ……..….……. pg. 5 Chapter 2: The Importance of Vitamins……………………….…………….. pg. 9 Chapter 3: Be Good To Your Brain - B Vitamins………..…………………. pg. 14 Chapter 4: Other Memory Essential Vitamins………………………………. pg. 25 Chapter 5: Minerals That Advance Brain Activity…………….…………….. pg. 35 Chapter 6: Spice Up Your Memory……………..………….…………………. pg. 49 Chapter 7: Supplement Your Diet For Brain Health…..….…………………. pg. 83 Chapter 8: Resources………………………………………....………..……… pg. 98 4 Chapter 1 Natural Memory Enhancers Work For All Ages There are many people, including scientists, who believe that when people get older they lose around 30-50 thousand nerve cells (neurons) a day. This may sound like a lot (like telling a bald person that losing 100 strands of hair a day is normal), but the fact is that not only is it alright, it is normal. Our brain weeds out the old and useless cells to make way for new ones, and if we treat our brain right we will strengthen the ones we already have and build stronger new cells. In most cases, our lifestyle has a lot to do with the weakening of our brain cells. If we have a lot of stress; if we constantly get less sleep than we need; if we eat the wrong types of food (ones that harm our heart and body as well as our brains); and if we are stagnant and don’t get the proper exercise; if we drink alcohol to excess; if we smoke; etc. - these all cause our brains to become weak and stop functioning properly, and this leads to dementia. Stress and high blood pressure are the two most common ways to weaken our brain. Proper feeding of our brain is no less important than the feeding of our stomach, and our brain cells need a variety of nutrients in order to survive. Neuroscientists have found that there are a number of foods that contain vitamins and nutrients that are normal to our brain and bodily functions. Our bodies can produce some of them itself, but most are derived from the food we eat. That is why it is important to eat a diet that contains less unnecessary or “empty calories,” and more food that is useful, and often vital, to the proper functioning of our body and brains. Many foods have been classified as “brain foods” because they enhance the functioning of our brains. These foods are beneficial because they contain larger concentrations of the essential vitamins and minerals that help our brains perform to their maximum. In addition, many of these nutrients can only be found in certain foods, or perform as partners in other nutrients ability to be absorbed in the body. Grocery stores, pharmacies and herb stores contain shelves full of many products that are called “brain boosters” or “memory enhancers.” Simply because a label says it is does not make it so. Many products may have a reputation that they are good for your memory, but there is not sufficient data to confirm that, yet are being advertised as “brain boosters” or “memory enhancers.” Before adding any memory supplements to your diet, have your pharmacist check for potential interactions with any drugs or supplements you are currently taking. 5 "And, remember that 'natural' isn't always safe," says Dr. Evangeline Lausier, physician at Duke University, "When you think about nature, you often think of beautiful and harmless. But think about a lion and a wildebeest -- that's nature, too." Keep in mind that the United States Food and Drug Administration (FDA) does not regulate or test herbs and supplements as often as they do other drugs, which makes if hard to know how strong, pure and safe they can be. It is advisable to do your own research on reliability, side effects, dosage and interaction with other drugs, herbs and supplements before you start to use them. 6 Currently there is no particular diet to prevent Alzheimer’s, but studies have shown that the Mediterranean diet may lower risk for the disease, and may even help to prolong life. This diet has little red meat, and focuses on fruits, vegetables and nuts - with a moderate amount of dairy, fish and poultry. The most important source of healthy fats is the olive oil that is consumed regularly in the Mediterranean diet. It has also been found that a small amount of alcohol, especially wine, may also be of benefit to lower the chances for Alzheimer’s disease. Doctors don’t advocate, however, that people begin to drink alcohol as a way to fight off dementia. Caffeine has been found to have a small protective quality from dementia, but there is more research to be done here. Meanwhile, Dr. Lausier recommends using the “common sense” approach to enhancing your memory, such as avoiding things you know are bad for your brain, like smoking and excessive in alcohol. “Some of these changes may make more difference in the outcome than a lot of expensive drugs or supplements," she says. “Just the act of trying turns on parts of your brain that are getting cobwebs.” Add that to exercise, which enhances memory in a lot of different ways - one of which is generating more blood flow to your brain and aiding in the formation of new neurons in the part of the brain known as the dentate gyrus. Exercise also helps fight cardio disease, which has a direct effect on your brain health. Recent studies have shown it is never too late to benefit from exercise. In a recent study, 152 adults aged 70 to 80, with mild cognitive impairment, were given B vitamins and put on an aerobic exercise regime. After one year, they increased their memory and cognitive function. Many scientists question whether it is possible to improve your memory, and reverse the effects of dementia once the disease has progressed. Research has found there are simple and effective ways to improve memory, in addition to exercise. Many “brain foods” also have some effect, in addition to herbs, vitamins and minerals. What scientists do know is that certain foods actually can accelerate the rate in which our brains deteriorate. It is necessary to include the following in our diets, and a deficiency of these can lead to dying brain cells: Fats - Our brains are made up of 30% fat. A shortage of the “good fat” (unsaturated fatty acids) slows down activity in the brain cells, and could even erase memory. These acids improve blood circulation, which increases the flow of blood to the brain. Providers of these “good fats” are fish (omega-3 fatty acids), olive oil, sunflower seeds, soy, grapes and 7 nuts. Fats derived from animals, and imitation fat such as that from margarine, do not help to improve memory. Carbohydrates are a good source of glucose, which provides fuel for our neurons. We receive the vast majority of our carbs from the food we eat, such as grits, vegetables, grains, etc. There are good carbs and there are bad carbs. The bad carbs come from sugar, sweets and food made from white flour - that provides only short-term energy boosts. Simple carbs consume too many B vitamins that are necessary for brain activity and digestion. Although our brains needs carbohydrates to function, we have to limit the amount we provide, and make sure we feed ourselves from the complex carbohydrate group for best memory function. Proteins contain amino acids that are necessary for brain and nerve function. You can find these in fish, beans, lentils and brown (not white) rice. Vitamins are the leaders in our food group to get our brains to work properly - most especially vitamins from the B group. They play a daily role in our ability to recall and learn information, and a deficiency can create problems in thinking and memory. Minerals are in our bodies as well as found in our food and the atmosphere. Most of these minerals are good for you, but like many things in excess can also do damage. Enzymes are mixed with other body chemicals, enzymes and nutrients to form a chemical reaction. These chemical reactions make the cells work faster and more efficient. An enzyme inhibitor slows the activity of the cell - like drugs or toxic substances. I hope I can provide a clearer picture as to what vitamins and minerals your body needs, where you can get them, and what happens if you are not getting enough. Food for thought 1. What do you think is more beneficial to a good memory, keeping the body healthy or supplementing your diet with additional nutrients? 2. Is a bad memory something you only have to worry about as you get older? 8 Chapter 2 The Importance of Vitamins Your mother was right when she stressed the importance of eating your fruits and vegetables. The power vitamins have to protect your brain and other parts of your body is enormous, and if you are lacking in a certain necessary vitamin it is important that you supplement your diet in order to avoid problems later on. We get the majority of our vitamins in our food, but unless you are on a specially prepared diet that contains the appropriate level of every vitamin your body needs you have to look for other places to make up for the inadequacy. The more processed food you eat out of a box, or at a fast food restaurant, the less chance you have of getting natural vitamins into your system. This may surprise you, but we need more vitamins and natural minerals as we age then we do when we are young. This is because our bodies have to find ways to repair the damage caused by pollutants in the air, water and food, and from free radicals and stress that plays havoc with our brains. There is overwhelming evidence that by taking a variety of different vitamins and minerals you are insuring your brain against loss of mental function. As a matter of fact, unless you take too much of certain vitamins, you are preserving your brain function and emotional well-being. It wasn’t until quite recently that the role of vitamins in our health was actually known. Ancient explorers found that, when traveling on ships that were only supplied with salted meat and grain, a large assortment of diseases took place, with many wiping away entire crews. When they varied their diet, including adding more vitamin rich fruit and vegetables, the diseases often were cured, or eliminated altogether. Several Nobel Prizes were won by scientists who were able to identify specific vitamins that saved thousands of people from disease and illness due to deficiency. Avitaminosis is the general term for any disease caused by chronic or long-term vitamin deficiency, or an inability of the body to metabolize the vitamins. Vitamin deficiencies are usually subtle, and often go undetected for long periods of time. They don’t always show up in blood testing either. 9 There still are developing countries with starving people who get diseases caused by vitamin deficiencies, but it is nowhere near as bad as it was decades ago. One study, however, actually found recently that 40%-60% of people still are deficient in vitamins they get solely from their diet. Optimum intelligence, memory and mood changes for the better are found when adequate supplies of vitamins are restored. The Dietary Guidelines for Americans 2010 states that “You should try to meet your nutritional needs through foods rather than taking vitamin or mineral supplements”. There are some specific groups of people who should take vitamins, such as pregnant women, who need folic acid, iron and vitamin C. To find out if you actually need to take vitamins supplements, the Food and Drug Administration (FDA) suggests you ask yourself: Is your diet restricted? Do you eat fewer than two meals a day? Are you losing or gaining weight? Do you take more than three different medications a day? Do you drink more than three alcoholic beverages a day? They also suggest you consult a health care professional about your own personal situation. Your doctor needs to tell you what you need for your diet. If your diet is not as good as it should be, perhaps a multi-vitamin is best for you. Check the label to see if it has 100% of the daily requirements. Vitamins and supplements may not be of benefit to everyone. Consult with your physician before using any vitamins to improve your memory. Too much of any one vitamin can be toxic, and may interfere with medication you are currently taking - either making them useless or not as effective. If you are on medication for memory impairment, do not replace the medication with vitamins. Your doctor can work with you to figure out if supplements will provide any added benefit. Clinical studies on vitamins and their effect on memory A recent study out of the France involved 4,500 French men and women between the ages of 45-60. They worked with these same subjects for nearly a decade. They randomly split the people into two groups, half of whom took a daily supplement that included vitamins C and E, selenium, zinc, and betacarotene for eight years. The others took a nutrient-free placebo pill each day. No one knew who was taking the vitamins and who was taking the placebo. 10 They found that the group taking the vitamin and mineral supplements performed better on memory tests than those who did not take the supplements. The researchers said that the findings would suggest that adding supplements to the diet as we age would help with our thinking and memory skills. Researchers in the study, Emmanuelle Kesse-Guyot of the University of Paris XIII in France and her colleagues wrote that “The link between a higher intake of some nutrients, thinking and memory skills has been shown before in so-called observational studies, but those studies can't get at a cause-and-effect relationship.” "The question is, does the cognitive performance depend on the diet, or does the diet depend on the cognitive performance?" McNeill told Reuters Health. It's possible that people who have better thinking and memory skills might pay closer attention to what they're eating, she explained. When eight years of the study were up, participants were taken off their assigned pills and given a choice on their own as to whether to take the supplements or not. Six years after that, they were brought back to the lab for a round of memory tests, including word and number problems to measure different types of memory and "mental flexibility." Although both groups performed closely on most of the tests, the group that had taken the supplements beat their peers out on long-term memory tests, where participants had to recall words in different categories. "Our results have to be considered carefully," the authors wrote in the American Journal of Clinical Nutrition. Although they added, the "findings support a beneficial effect of a well-balanced intake of antioxidant nutrients at nutritional doses for maintaining cognitive performance, especially verbal memory." "Vitamins and minerals are important for memory in fighting off the free radicals that do the damage, but they're not the only thing that's important," Barbara Shukitt-Hale, a nutrition researcher at Tufts University in Boston told Reuters Health. "The most important thing is eating a healthy diet, being active, and keeping your brain sharp." 11 Which vitamins are the best for your brain? According to information in the book Your Miracle Brain, by Jean Carper (Quill, 2000), here are a few all-star brain boosters: Folic acid revitalizes memory Vitamin B6 boosts memory Vitamin B12 prevents “senility” Thiamin is a psychiatric “drug” Niacin is a universal memory pill Vitamin E is a super brain pill Vitamin C is a brain saver Selenium is a brain boosting mineral Lipoic acid is a number one antioxidant Coenzyme Q10 is a brain energizer Ginkgo boosts aging brains Phosphatidylserine (PS) is a memory rejuvenator Choline is necessary for the brain’s memory architect Huperzine shows promise as an Alzheimer’s Drug St. John’s Wort is a natural Prozac Sam-E is another natural antidepressant When talking about vitamins it is important that we add enzymes to the discussion of supplements, herbs, vitamins and supplement in order complete the neuroconnections. Lack of certain enzymes are just as important to look out for as too much. As with all nutrients, a balance needs to be maintained in order for your brain to run smoothly. According to the National Institute of Mental Health, one enzyme in particular, PKMzeta, is responsible for maintaining long-term memory. The PKMzeta enzyme is thought to make connections between brain cells where others cannot. Blocking this enzyme can erase components of one's long-term memory, whereas stimulating the production of this enzyme may enhance long-term memory and counter cognitive degeneration that occurs in the aging process. Researchers have suggested that the PKMzeta enzyme can be used to block harmful memory experiences in post-traumatic stress disorder, or enhance brain functioning among individuals with dementia or Alzheimer's. Further research is need before treatment is available. 12 Food for Thought 1. Do you think you are getting adequate vitamins in your regular diet, or do you think a multi-vitamin or supplements are necessary? 2. Would you consult a health care professional before taking supplements, or do you think you can adjust your intake accordingly? 13 Chapter 3 Be Good To Brain - B Vitamins Vitamins in the “B” group are perhaps the most important of all the vitamins for brain development and memory. Research has found that B vitamins improve memory by forming a protective shield for the neurons in the brain. The B vitamins break down an amino acid called homocysteine that is a toxic poison to nerve cells. These vitamins also help to produce red blood cells, which carry oxygen to the brain. B vitamins are also known as B complex vitamins. They consist of eight water-soluble vitamins that play an important role in cell metabolism, where the body’s cells get energy and nutrients from the food you eat. Initially they were thought to be only one vitamin because they were found together in a number of foods. They also play a key role in the creation of new cells, and in the conversion of food to energy. There are eight vitamins in the B vitamin group…B1, B2, B3, B5, B6, B7, B9, B12. The most important B vitamins for memory are B6, Folic Acid (B9), and B12, although all the vitamins in the B group play a role in brain and memory development and retention. Consuming healthy, natural food like dark, leafy greens - broccoli; spinach; asparagus; fruits such as strawberries, melons and citrus oranges and grapefruits; and leeks, beans and soybeans are all excellent sources of B vitamins. You can also take supplements if you are not getting enough of your B vitamins in your food. Nutritionists have been saying for a long time that memory problems can stem from the lack of adequate B vitamins in your diet. Initial research has upheld that belief, indicating that severe B vitamin deficiency can lead to memory problems. Here is the list of the eight B vitamins, their properties and benefits, and the problems that exist if there is a vitamin deficiency: 14 B-1 (Thiamin) Vitamin B-1, also known as Thiamin, was the first in the series of B vitamins to be discovered, and works in conjunction with other B vitamins to metabolize food and support other functions of the body. B1, in particular, plays important roles in normal brain health and function. Having a B1 deficiency can lead to numerous problems relating to neurological function. In clinical trials it has been found to bring on increased concentration, faster reaction times, and clear-headedness. Vitamin B1 helps the body to absorb and process glucose, which gives the brain cells their primary source of energy by breaking down carbohydrates into sugar, also known as blood glucose. Too much or too little blood glucose affects brain function. You may feel tired, fatigued and unable to focus if your blood glucose falls too low. A balance needs to be maintained for good brain function. Vitamin B1 is important for a variety of other biochemical reactions, including the blending of brain chemicals, or neurotransmitters, which allow brain cells to function and communicate with one another. Last, but not least, vitamin B1 can help reduce or prevent oxidative stress throughout your body when harmful free radicals react with healthy cells, causing permanent damage. A deficiency of vitamin B1 greatly impacts brain health and can lead to various types of dementia. According to researchers at the Linus Pauling Institute, a thiamin deficiency is a common factor in patients diagnosed with Alzheimer's disease. This is due to a decreased function of transketolese and ketoglutarate dehudrogenase, two enzymes that are metabolized by thiamin to make glucose. Without the adequate functioning of these enzymes your brain cells may not be getting the glucose they need to function, which can lead to dementia. Thiamin deficiency can lead to a disease called beriberi. The symptoms include body fatigue and pain, weight loss, brain damage, irregular heartbeat and heart failure if left untreated. Those who frequently drink alcohol are at risk of beriberi. After years of abuse of alcohol, the cells in the gastrointestinal tract are damaged and not able to absorb the vitamin effectively. 15 Wernicke’s encophalophy, or Wernicke-Korsakoff syndrome, is a thiamin deficiency that affects the normal function of the brain. It is characterized by confusion, memory loss, delusions and eye problems. It is commonly related to alcoholism or difficulty in absorption of vitamin B-1. The lower parts of the brain, the thalamus and hypothalamus, become damaged and cause confusion, poor muscle coordination and vision problems. According to the National Institute on Alcohol Abuse and Alcoholism, Korsakoff syndrome damages parts of the brain that are responsible for memory. This syndrome develops as Wernicke symptoms diminishes and leads to chronic hallucinations, loss of long-term memory and inability to retain information. This also could explain why alcoholics have difficulty with processing thoughts, even after they are sober. You should be getting an adequate supply of thiamin in your diet. Vitamin B1 can be found in eggs, lean meats, legumes, nuts, peas and whole grains like wheat germ, sunflower seeds, green peas and whole-wheat bread. If you don’t eat enough of these foods, taking a multivitamin or vitamin B-complex often provides all of the B1 you need. B-2- Riboflavin Riboflavin plays a key role in energy metabolism, and for the metabolism of fats, ketone bodies, carbohydrates, and proteins. True riboflavin deficiencies are rare, although about 10% of people in developed countries do have a slight deficiency due to a diet of high processed foods. Continuing slight deficiencies could increase the risk of mild health problems. This condition is present mostly in people who suffer from alcoholics or malnutrition. The symptoms are distinctive bright pink tongues, cracked lips, throat swelling, bloodshot eyes, and low red blood cell count. Ultimately it can cause comas and death. It usually can be reversed in most people simply by eating foods rich in riboflavin, however it is absorbed through the liver, so alcoholics might eat enough of it but still be deficient because their body can no absorb it. Foods rich in vitamin B2 include meat, eggs, milk, mushrooms, and leafy green vegetables. Vitamin B2 is also used as artificial orange color in foods. 16 B-3 - Niacin In recent tests conducted on mice, Nicotinamide, a form of vitamin B3, has been found to reduce the symptoms of Alzheimer's disease. The effects on humans needs further testing. Aside from the belief it could reduce the risk and effects of Alzheimer's disease, vitamin B3 also reduces the risk of heart disease and lowers LDL cholesterol. Vitamin B3 is an important brain vitamin. It helps increase blood flow to the brain, lowers blood pressure, and reduces blood cholesterol. There are also studies to support the memory enhancement qualities in niacin, by increasing memory by as much as 40% per day with a one a day supplement of 140 mg of the vitamin. Dr. J. Richard Wittenborn of Rutgers University has used Vitamin B3 as a part of his treatment for schizophrenia. He has found significant improvement in certain patients, however, there have not been many other studies that support the link between schizophrenia and vitamin B3 deficiency. Vitamin B3 deficiency can lead to a wide range of health problems, from a physical level such as dermatitis and diarrhea, to severe brain disorders like dementia. In earlier times, after the discovery of America, a disease called pellagra began to spread among the settlers. Their symptoms included diarrhea, dermatitis, dementia and finally death. Many of the settlers believed the corn was poisoning them, but were not able to explain how the native people did not get sick and they consumed a lot of corn in their diet. After thousands died, someone discovered that, although the natives ate the corn, they added lime as a treatment. The European settlers did not like the taste of the corn with lime, so did not use it. Lime was the source of the niacin for the Indians, and so they were not deficient in the vitamin. Once the settlers were able to add B3 to their diets the disease all but disappeared. Tuna, chicken, turkey, salmon, tofu, calf’s liver, peanuts, cottage cheese, milk and asparagus provide a significant source of vitamin B3. 17 Reduced B-nicotinamide adenine dinucleotide, or NADH, is a form of Vitamin B3 that boosts energy in cells throughout the body. It also helps with production of the neurotransmitters dopamine and norepinephrine in the brain. Studies indicate that NADH may be useful in the treatment of Alzheimer's and Parkinson's disease. B-5 Vitamin B5 is found in nearly every food that we eat, so deficiencies are only usually found in people who are starving, those on special diets, and in clinical studies where the vitamin has been eliminated or reduced. A deficiency in vitamin B5 causes chronic paraesthesia. Paraesthesia is most familiar to us as the numbing sensation we feel as ‘pins and needles’ or a limb ‘falling asleep’ that we experience from time to time. Paraesthesia is perfectly normal in this situation; however, in vitamin B5 deficiencies it happens quite often. Prisoners of war who experienced malnutrition sometimes reported prickling and burning sensations in their hands and feet, which many doctors now believe to have been paraesthesia. Since this is not as common today, vitamin B5 is not usually found in vitamin supplements. B-6 (Pyridoxine) Vitamin B6, also known as pyridoxine, plays an important role in the formation of neurotransmitters or brain nerve messengers. A deficiency of B-6 can result in depression and mental confusion. Aside from maintaining many of our bodily functions, vitamin B6 has been shown to improve memory while supporting brain health. Research shows over time that a daily intake of vitamin B6 resulted in improved memory, and the brain was able to process information at a faster rate. Vitamin B6 helps convert 5-hydroxy-tryptophan (5HTP) in into the mood chemical serotonin, and also helps in making dopamine, our mood and alertness chemicals. A diet containing from 2-10 milligrams a day of B-6, either in supplement form or eaten in your diet, will do wonders for your brain health. B6-rich foods include bananas, eggs, carrots, bell peppers, cranberries, turnip greens, cauliflower, garlic, tuna, mustard greens, and kale. For your body to absorb more vitamin B6 from food, avoid smoking and excessive alcohol consumption. 18 B-7 Biotin, or vitamin B7 is found in most meat, liver, milk, peanuts and some vegetables. A deficiency causes rashes, hair loss, anemia, and mental conditions including hallucinations, drowsiness, and depression. Biotin travels in the bloodstream and eliminates the excess through the urine. The body does not build up reserves of vitamin B7, you have to ingest it daily in your diet or a supplement. Mild biotin deficiency is also found is about half of all pregnant women due to a higher use of vitamin B7 in their bodies, and the World Health Organization recommends supplements are recommended for such women. There was a brief spike in the number of cases of biotin deficiency when it became popular for bodybuilders to consume raw eggs because one of the proteins found in raw egg white binds vitamin B7 and makes it difficult for the body to use, leading to a deficiency. Cooking egg whites makes this protein inactive. B-9 - Folic Acid The B vitamin folic acid has been closely linked to fighting off dementia and Alzheimer’s disease, and reducing the rate of memory loss in the elderly. Among healthy people, lower levels of folic acid is believed to be linked to lower scores on memory tests. Folic acid helps to send oxygen to the brain by helping in the production of red blood and controlling the levels of homocysteine in the blood. Homocysteine, at elevated levels, is known to damage brain cell, so adequate supplementation with folic acid is strongly advised if you lack brainpower. Folic acid has also been reported to improve shortterm memory and alertness. If you take folic acid, you will feel more mentally alert, instead of being sluggish and lethargic. This vitamin is found in a wide variety of foods, especially liver and raw vegetables, legumes, nuts, avocados, cereals, and spinach and other leafy greens. Normally, a well-balanced diet provides enough folic acid, but low-dose supplements (200 to 500 micrograms) seem safe. You need to seek medical advice if you plan to take higher levels of folic acid. 19 Foods high in folic acid prevent the breakdown of neurons, and help to keep your overall nervous system healthy. They include: Okra Spinach Lentils Black Beans Garbanzo Beans Collards Romaine Lettuce Asparagus Sunflower Seeds Black-eyed Pea Orange Juice Tomato Juice You can find folic acid supplements in most local drugstores. Foods rich in folic acid include leafy green vegetables and legumes, such as beans and lentils. B-12 (Cobalamin) Vitamin B12, or cobalamin, takes on a number of roles, including helping in the formation of myelin. Myelin acts as insulation around nerve cells to form l The brain needs this vitamin to maintain healthy function and help with the formation of red blood cells. Deficiency of vitamin B12 known as hypocobalaminemia is gradual, causing deterioration of the spinal cord and very gradual brain deterioration that could result in loss of sensory or motor skills. Mental disorders from the gradual brain damage begin to show themselves as fatigue, irritability, depression, or bad memory. As the disease progresses over several years, psychosis and mania can appear. This damage is irreversible. Fortunately, this vitamin is found in enough foods, and if need be supplements, that it is not as common as it once was to have a deficiency. It is most often found in developing countries in those who follow a vegetarian or vegan diet. "Sometimes as people age, they have impaired absorption of B12," says Kimball, a nutritionist at the Ochsner Clinic's Elmwood Fitness Center in New Orleans. In fact, B12 deficiency can present as similar to Alzheimer's disease,” she says. "My grandmother couldn't make sense until her doctor supplemented her B12," she tells a reporter at WebMD. You should aim for between 3 and 100 micrograms of B12 a day. Beef liver, roast beef, oysters, sardines and herring are high in B-12. Children need much more B12 than adults because they are growing, so infants who are only breast- 20 fed can become deficient and suffer permanent brain damage if their mother is only slightly deficient. A study published in Neurology in 2010 evaluated the blood and levels of Vitamin B12 in 271 normal individuals between the ages of 65-79. The study ran for seven years and chose this age range because of the high risk in these age groups for memory loss and stroke. Vitamin B-12 helps maintain healthy nerve cells and red blood cells. A vitamin B-12 deficiency, most common in vegetarians and older adults, can cause various signs and symptoms, including difficulty in memorizing, remembering names and faces and cognitive functions. In this study, holotranscobalamin, the active ingredient in vitamin B12 is believed to lower the homocysteine blood levels associated in the prevention of brain shrinkage, reduces the risk of cognitive impairment, memory loss and dementia. Older people commonly have a low blood level of B12 (below 170-250 picomol per ml), and their risk for memory impairments are much greater. Results from the study showed the risk for Alzheimer’s Disease (AD) decreased by 16% for micromolar increase of B12 in their blood. To put it into non-scientific terms: The higher your level of B12 in your blood, along with other risk factors, the better your risk of preventing Alzheimer’s or any other form of dementia. Although B12 is not the only consideration, this study shows there is good evidence to believe a lower level of B12 is a good indicator there could be memorizing and cognitive problems, and that more research will could prove or disprove this theory. Over a 2-year period the subjects in the above study were given significantly more than the average minimum daily requirements on a vitamin bottle. That does not disprove the theory, but holds out new confidence that further study will come back with the message that vitamin B12 does help improve your memory, and is one of those valuable brain foods your body needs to help improve memorizing and cognitive functions. Unfortunately, with age some people lose the ability to absorb enough B12. Some 20 percent of people over the age of 60 can't absorb enough B12; that percentage jumps to 40 percent by age 80. For this reason, older individuals might want to choose cereals that are fortified with B12 or consult a doctor about taking a B12 supplement. 21 Some diseases (such as Crohn's disease), as well as surgical removal of the intestine, can also result in poor B12 absorption. In a small number of cases, chronic B12 deficiency requires injections of the vitamin on a monthly basis. Scientists have known for a long time that vitamin B12 and folate are important to the body, but until their recent discovery that some people are actually born with a gene that shows a predisposition to dementia and Alzheimer’s they did not associate vitamin B12 and folate with memory loss. As a matter of fact, until now only a few researchers have explored how nutrition and our genes work together to promote better memory function. Researchers, funded by the Agricultural Research Service (ARS) and reported in the November 30, 2007 edition of Science Daily, delved into the co-relation between the decline in memory and cognitive function in senior citizens and their intake of two B vitamins – vitamin B12 and folate. Both these vitamins are important in the development of healthy nerve and blood cells. The scientists found an interesting association among seniors aged 60 and older whose vitamin B12 blood levels were low and mental decline. They found also, that taking stomach-acid blockers could contribute to a gradual lessening of B12 absorption in the body. Although scientists determined long ago that a serious deficiency in vitamin B12 leads to declining cognitive and memorizing abilities, they are still working on the implications that having too much folic acid (from fortification in food), and too little vitamin B12 (due to poor body absorption) have on memory and cognitive functions. According to Martha Savaria Morris, PhD, epidemiologist at the USDA HNRCA, "we found a strong relationship between high folate status and good cognitive function among people 60 and older who also had adequate levels of vitamin B12." "People with normal vitamin B12 status performed better if their serum folate was high," explains Morris, "But for people with low vitamin B12 status, high serum folate was associated with poor performance on the cognitive test." Seniors with low vitamin B12 status and high serum folate were also significantly more likely than seniors in other categories to have anemia, a condition caused by reduced amounts of hemoglobin in oxygen-carrying red blood cells, or by a deficiency in the number or volume of such cells. "For seniors, low vitamin B12 status and high serum folate was the worst combination," says Morris. Vitamin B12 deficiency, which many seniors have due to decrease in the body’s ability to absorb the vitamins as it ages, can have an impact on the DNA needed to grow new cells, and for neurological function. Folate and vitamin B12 are believed to work together to prevent mental decline. Vitamin B12 can be found in meat, fish, poultry, eggs, and dairy products. It can also be found in supplements, or as injections given by your doctor. Folate is 22 found in leafy green vegetables, beans and citrus fruits. Since 1998 the U.S. Food and Drug requires that all enriched cereal-grain products be fortified with folic acid, the synthetic form of folate, to help prevent birth defects in infants. This governmental requirement has led to some individuals having too much folate in their diets. So, when your mother told you to take your vitamins she wasn’t just trying to get your body to remain healthy, she was actually accelerating your learning and improving your memory by providing you with natural brain food. Choline Choline is not officially a B vitamin, but is usually lumped in with them. It is the formative molecule for the neurotransmitter acetylcholine, which is involved in many functions including memory and muscle control. In order for our body to produce acetylcholine it needs a nutrient called choline. As our brains get older we are not able to produce choline as well as we once did and we end up with a choline deficiency. By increasing the amount of choline that gets to the brain we increase our brain and memory power. Research conducted at Duke University showed that rats by injected with choline had far superior brains to other rats, with more neural activity. The rats were able to learn quicker and remember more - and this lasted into old age. Scientists at the University of North Carolina discovered that if pregnant rats don't get enough of the B vitamin choline, the learning and memory centers in the brains of their developing offspring could be permanently affected. Whether the same holds true in pregnant women who get too little choline is not yet known. (If you are pregnant or trying to become pregnant, be sure to discuss vitamin and mineral supplementation before conception or as early in your pregnancy as possible. But don't take any over-the-counter or prescription supplement or drug without clearing it with your doctor first.) Milk has a high concentration of choline, and can be found in supplements, although it does have a fishy smell. You will be amazed at the greater mental performance you will receive, almost immediately, even for people with severe mental decline. 23 Food for Thought 1. After learning about all the advantages to taking B vitamins, are you going to look into eating more food that contains these highly brain-boosting vitamins? 2. Do you believe the studies that say B vitamins are memory boosters? 24 Chapter 4 Other Memory Essential Vitamins We are learning that the proper nutrition is essential for maintaining top brain performance, and it could be possible you may not be getting all that you need from your normal diet. The vitamins in the B group are extremely important, but they are not the only vitamins that aid in maintaining and improving brain function and fight off memory loss. You many want to include these essential vitamins in your daily diet or supplement routine. When you lack certain vitamins your body is tired, your skin starts to sag and take on different colors, your teeth and bones are affected, and in some cases serious illness could take place, sometimes fatal. Vitamins work with other nutrients to interact and help in metabolizing food, digestion and in developing blood cells. Some vitamins are reported to help slow down the aging process, prevent cancer cells from forming, and to strengthen the immune system. There are 13 different vitamins, and they are divided into two types of categories - water soluble and fat-soluble. Water-soluble vitamins can be absorbed and dissolve quickly into the bloodstream. They need to be consumed from foods every day because the excess is passed through the urine and can’t be stored in the body. Water-soluble vitamins play an important part in the metabolizing, break down, and digestion of protein, fats and carbohydrates - bringing about the subsequent release of energy into the body and without an adequate supply of these vitamins, these processes may not be properly completed. The fat-soluble vitamins - A, D, E and K, are absorbed in the intestine. They do not have to be taken every day, since they are stored in the liver. Most vitamins can be found in fruits and vegetables, and for optimum results should be eaten raw, as the cooking of them depletes their power. Just as the right amount of vitamins are essential for your health, too much can be harmful, so check before adding supplements of any vitamin to your diet. 25 Vitamin A - Retinol Stress is one factor that destroys your memory and other brain functions. Over time, stress does a lot of damage to your brain cells, causing them to die out or lose strength. Vitamin A helps your body in dealing with stress. It has antioxidant properties that provide protection against damaging free radicals in the brain. Vitamin A is important for the forming of healthy teeth and bones, mucous membranes and skin, and aids in vision (especially night vision). Vitamin A is fat soluble, so it is stored in the liver. Because of this, too much vitamin A can result in a build up of the vitamins that could damage the liver. A deficiency in vitamin A can contribute to poor night vision, eye problems, a weakened immune system, and makes one more prone to infections. Research has found that chronic infection is very damaging to the brain, and can cause acceleration in aging and dementia. Vitamin A helps in building of the immune system and fight against infection. Food sources of vitamin A are carrots, sweet potatoes, apricots, cantaloupe melon, broccoli, spinach, pumpkin, meat, eggs, oily fish, liver, milk, cheese, and kidney. Yellow, orange, and green vegetables are rich in beta-carotene, a powerful antioxidant that converts to vitamin A in your body. Vitamins C (Ascorbic Acid) Free radicals, atoms and molecules that are often a byproduct of a chemical reaction in your body involving oxygen, can damage your brain cells. Research clearly shows that free radicals damage the brain during normal aging as well as in Alzheimer's disease. Antioxidants help to eliminate free radicals from your body, and vitamin C is most available antioxidant on the market today. Ensuring enough vitamin C in your body will help improve your brain’s overall function. Getting enough of vitamins C may also help perk up a lapsing memory and keep it sharp, and help to ease some of the stress put on brain cells by free radicals, which are released during normal chemical reactions in the body. Vitamin C is required daily because it is water-soluble, and is a necessary vitamin for a number of body functions. It is required for the formation of collagen, which helps to maintain skin, teeth, gums, tendons and ligaments. It helps to heal wounds quicker, strengthen the immune system, and fight off cancer cells. 26 Vitamin C is also required to form neurotransmitters, such as dopamine in the brain, and helps to reduce any damage to the body from toxic substances and chemicals. Although when you take your vitamins is not important, what you take with them is. Vitamin C helps you absorb iron, so taking your vitamin C at the same time you take your iron can be beneficial. Vitamin C can also aid in the absorption of aluminum, like that found in antacids, so if you take your vitamin C two hours before or four hours after you take an antacid you will get better results. On the other hand, sometimes, one vitamin can interfere with another vitamin. For instance, if you take large doses of vitamin C, it may hurt in the absorption of vitamin B-12. Vitamin C can also interact with estrogen, warfarin, acetaminophen and aspirin, so you should not take it in combination with any of those medications. Vitamins C is linked to helping keep your arteries open and functioning properly. It also has been found to improve your memory and reasoning powers due to its antioxidant properties. Vitamin C plays a significant role in neurotransmitter regulation, and aids in the manufacture of norepinephrine, a major neurotransmitter that acts as a stimulant. We need this vitamin, therefore, to fight stress and keep the brain active. Smoking and alcohol consumption may lead to vitamin C deficiency. A recent study found a correlation between memory problems and babies who suffer a vitamin C deficiency. Another study found that vitamin C protects against memory problems and loss of mental alertness. Researchers from Johns Hopkins University found that people taking vitamins C were 78% less likely to have had a diagnosis of Alzheimer's at the study's start and 64% less likely to have developed the disease four years after the study began. If you are taking supplements, aim for 500 micrograms once or twice a day, she says. Vitamin C is water-soluble. This means that it is not stored inside your body, so you should have an adequate supply of it in your diet. Vitamin C is essential for brain health as it helps to protect your brain from free radicals. The University of Maryland Medical Center states that free radicals are unstable compounds that form when your body converts food into energy. A build-up of free radicals may harm the brain, turning it brittle and possibly contributing to the development of 27 brain cancer. Vitamin C can be found in foods such as cabbage, blueberries, red peppers, cooked leafy greens, pineapples and oranges. Because vitamin C is relatively safe, and are essential to proper functioning of many different areas of the body, ensuring adequate intake of them-and even getting more than the recommended daily allowance-is not likely to be harmful. It's still best to consult your doctor before taking higher-than-recommended doses. Of course, before taking any supplements talk to your doctor first, many may interfere with the absorption of medications you may be taking or may cause bothersome side effects. Those with a vitamin C deficiency (also known as scurvy) are prone to more infections, slower healing, dental and gum disease, lethargy, loss of appetite, dry skin, painful joints, anemia and a slower metabolism. It also could be fatal if left untreated. You can find vitamin C in a wide variety of fruits and vegetables, citrus fruits, melon, strawberries, blackcurrants, green peppers, tomatoes, broccoli, kiwi fruit, potatoes, dark green leafy vegetables, red peppers, squash, mango, papaya, cauliflower, pineapple, blueberries, raspberries and cranberries. Vitamin D Vitamin D is manufactured when the body is exposed to sunlight. Exposure to the sun three times a week, for a period of 10-15 minutes each, is enough to produce the necessary requirements. Inadequate amounts have been found to increase the rise of dementia. In a study published in the Archives of Internal Medicine (July 12, 2010), vitamin D not only helps to ward off dementia, it may also prevent Parkinson’s disease and help to maintain normal brain health. Findings in the study showed that about 60 percent of individuals with a vitamin D deficiency experienced a decline in thinking, memory and learning. Vitamin D helps to maintain strong bones and teeth, and can prevent osteoporosis. It is needed to absorb calcium. Baby boomers (people ages 47 through 65) are becoming more health and memory conscious as they enter what some term as “The Golden Years”. As we age our ability to remember and process information starts to diminish. Since research has shown that there are a number of things we can do to slow down that process, and even halt age-related memory problems altogether, more and more people of the aging population are seeking ways to enhance their memory fitness. One of these ways may be to take in more vitamin D. 28 A study linking vitamin D to cognitive function was funded by the Agricultural Research Service (ARS) and published in Journals of Gerontology. It set out to find out whether aging boomers can slow down their mental decline by getting more vitamin D in their life, since the brain’s pathways for metabolizing vitamin D in the brain’s hippocampus and cerebellum regions are involved in forming new memories, as well as cognitive functions like planning and processing information. More than a thousand boomers receiving home care participated in the study. As people age they tend to take in less vitamin D and spend less time out in the sun. Researchers in this study believe that the decrease in vitamin D intake could play a part in mental decline. Participants were given psychological and blood tests and results were studied among the three categories of vitamin D blood concentrations: deficient, insufficient or sufficient. Vitamin D is a fat-soluble vitamin that is not present in very many foods. You can get vitamin D from the sun, when ultraviolet rays from sunlight strike the skin and trigger vitamin D synthesis. It is also found in cod liver oil, fish, eggs, and as an additive in milk and dairy products, or in supplemental form. Vitamin D promotes calcium absorption in the stomach, and is needed for bone growth. Without a sufficient supply of vitamin D bones can become brittle, thin or misshapen, which is why many older people get broken bones easily. Added to calcium, vitamin D also protects older adults from osteoporosis. The results of the study found that 35% of the participants had sufficient vitamin D in their system and had better “executive performance” in tests that measured their perception, cognitive functions and reasoning than those who were deficient or had insufficient amounts of the vitamins in their blood. Other variables were also taken into consideration in the testing. This would suggest that seniors and those approaching the senior stage in their life can do well to get plenty of vitamin D in their diet, and from the sun, to help boost their memory fitness as they age. Since Alzheimer’s disease, the most common form of dementia, affects approximately 47% of the population over the age of 85, and people are living longer, identifying nutritional factors that could help to enhance their quality of life by maintaining their memory function and cognitive vitality is very important for the boomer, their family and as a public health benefit as well. A lack of vitamin D (rickets) has been shown to disrupt the brain's ability to plan, process and form new memories. One study suggests that the decreased level of vitamin D in the elderly is associated with the loss of memory due to aging. The 29 softening and weakening of the bones and muscles, insomnia, and nervousness also signify rickets. It can cause permanent deformities in children. It is relatively rare in developed countries, but in others is most common in infants and children who have poor diets or are housebound. Breastfed infants, where their mothers do not get enough sunlight, are at higher risks. In recent years there has been a slight increase in children with rickets possibly due to too many of them staying indoors. Rich sources of vitamin D include cheese, oysters, fish and fortified milk. dairy produce, oily fish and fish oils, eggs, oysters and fortified cereals. Look to eating more mackerel, tuna and foods fortified with vitamin D to increase your daily intake of this vitamin. Vitamin E (Tocopherol) Vitamin E is an important antioxidant that is essential for protecting the tissues and cells from free radicals and other harmful substances. Research has found that by adding a supplement of vitamin E to your diet it can delay the progress of Alzheimer’s disease, or possibly prevent it altogether. As a matter of fact, antioxidants can prevent a lot of brain disorders, like Parkinson’s. In addition to brain function, vitamin E is important in the prevention of cancer, cardiovascular and heart disease. It is also used in skin creams because it may be possible to prevent aging in the skin. Vitamin E can help prevent strokes by strengthening the blood vessels and protecting them against damage from oxidation. A twoyear study by the National Institutes of Health (NIH) found that it can help slow the brain deterioration in Alzheimer's patients. Brain degeneration happens when oxidation of free radicals causes the build up of amyloid, a protein substance that interferes with the neurological network. The antioxidant properties in vitamin E can help decrease amyloid level and keep the brain in good shape. Vitamin E is fat-soluble, so it is stored in the liver. It is important for the production of red blood cells, essential for transferring oxygen to the brain and other cells throughout your body, and helps to reduce the pathogenesis of dementia and improve the health of your brain cells. There is also evidence that vitamin E can keep nerve cells in the brain from dying after suffering a stroke. It has been found to improve the memory function of the elderly. 30 Although vitamin E apparently doesn't decrease the risk of developing Alzheimer's, it may slow its progression. Free radicals, produced during normal chemical reactions in the body, can damage brain cells. Vitamins E act as an antioxidant, neutralizing free radicals and easing up nerve and brain cell stress. In a study of patients with Alzheimer's, treatment with 2000 IU of vitamin E per day for 2 years was beneficial in delaying the primary outcome (time to the occurrence of death, institutionalization, loss of ability to perform activities of daily living, and severe dementia) of disease progression. There are some warnings if you are thinking of taking a vitamin E supplement. Vitamin E deficiencies are not common, but may include some nerve damage. It interferes with absorption of some antidepressants and can make them less effective. Cholesterol-lowering medications can decrease the absorption of vitamin E and bring down the levels of vitamin E in the blood. If you are taking the anticoagulant or blood-clotting drug, like warfarin, taking vitamin E can increase the risk of abnormal bleeding. Recent studies have raised concerns about an increased risk of deaths in unhealthy people who take high doses of vitamin E, so be sure to consult with your doctor before taking this supplement. You can find vitamin E in leafy green leafy vegetables, nuts, seeds, wheat germ, grains, spinach, asparagus, cereals, sweet potatoes, sunflower, olive and soybean and vegetable oils such as canola, palm. Your local drug or health food store should also be selling this popular vitamin supplement. Vitamin K Vitamin K refers to a group of vitamins - vitamin K1 and vitamin K2. A range of other K vitamins called K3, K4 and K5 are used mainly in animal food. Plants synthesize Vitamin K1; Vitamin K2 is produced by both humans and animals, and by bacteria found in the large intestine. The ‘K’ in vitamin K is derived from the German word "koagulation" (English word is Coagulation), which is the process in which blood forms clots. Vitamin K facilitates the function of several proteins, including those that are responsible for the forming of blood clots. It plays a vital role in cell growth and the metabolism of bone and other tissues. Vitamin K has been shown to function within several systems in the body. It also maintains healthy bones, facilitates cell growth and prevents cardiovascular disease. Blood clots through a process called the ‘coagulation cascade’, which involves a cascade of enzymes activating each other. Fibrin, a protein that clumps together to make part of the plug/clot in an attempt to stop bleeding, is formed at the end of the cascade. The activation of some of the enzymes in the coagulation cascade is also dependent on vitamin K. 31 It is on this principle that oral anticoagulants like warfarin (Coumadin) function. While blood clots form naturally to stop us from hemorrhaging to death, they can also be dangerous if they lodge in the heart or blood vessels. This prevents blood from reaching its destination, resulting in the death of the target tissue, including brain tissue. Anticoagulants are prescribed to patients at risk of forming such clots. These anticoagulants block vitamin K function, resulting in decreased formation of clots. It is primarily vitamin K1 that is used when it comes to blood clotting. Vitamin K2 plays an important role in bone formation. It is also involved in the prevention of bone loss. Vitamin K modifies the protein osteocalcin, which gives osteocalcin the ability to bind to calcium. Calcium can then help to form the bone matrix. Recent research has shown that vitamin K also works with vitamin D to facilitate the function of osteoblasts, the bone building cells. On the other hand, it works to inhibit the production of osteoblasts (the cells which breakdown bone). Vitamin K is manufactured in the human gut. This deficiency affects nearly half of all newborn infants worldwide. Many hospitals give newborns vitamin K injections to avoid the more severe symptoms. Unfortunately babies born outside hospitals are statistically at a much higher risk of serious deficiencies. Newborns have not yet developed gut bacteria, which is why they are so prone to deficiencies. When there is a deficiency of vitamin K, osteocalcin does not bind with calcium, which means that calcium cannot bind to the bone matrix. With the lack of calcium bones eventually become porous. Calcium is then also free to travel in the blood, and eventually gets deposited in the arteries. This causes a hardening of the arteries, a condition also known as atherosclerosis. Other than newborns, vitamin K deficiency is found in alcoholics, bulimics, strict dieters, and people with various severe diseases such as cystic fibrosis. Adults who bruise or bleed easily sometimes have vitamin K deficiency which itself may be indicative of one of these more serious disorders. In severe cases of vitamin K deficiency, uncontrolled bleeding occurs, and underdeveloped faces and bones can develop. The protein Gas6 is dependent on vitamin K. This protein is important for regulating cell growth, preventing cell death, and helping cells to communicate 32 with each other. It could also be involved in the development of aging in the nervous system. Liver, cheese, green leafy vegetables and soybeans are all good sources of vitamin K1. However, only about 10% of the vitamin K1 in your food reaches your bloodstream, and vitamin K1 remains in your body for only a few hours before being secreted. About 80% of the vitamin K in the Western diet is vitamin K1. Dietary sources of vitamin K2 are rare. Vitamin K2's biggest function is to prevent the accumulation of calcium deposits in your arteries. When calcium deposits form in your arteries, your risk of heart disease goes up. Vitamin K2 removes calcium from your blood, and moves it to the bones and teeth. Therefore, vitamin K2 is essential for strong, healthy teeth and bones, as well as a strong, healthy cardiovascular system. Vitamin K2 is also a powerful antioxidant, and as such can prevent a range of health problems, including cancer and obesity. The antioxidants in vitamin K2 can help prevent free radical damage inside your body, to slow the signs of aging. Fermented foods, like cheese, soy tempeh, natto (a traditional Japanese soy food), spinach, cauliflower, kale, spring onions, sauerkraut and pistachio nuts are all good sources of vitamin K. Other sources include chicken breasts and livers, ground beef, egg yolk and butter. Butter made from organic, free-range milk is highest in vitamin K2. Vitamin P - Bioflavonoids Bioflavonoids are also known as vitamin P. They are super-antioxidants found in many natural foods, which contain specific capabilities to increase bodily health in many different ways. They support strong cell formations and some say even suppress poor cellular growth in order to deliver an anti-carcinogenic effect. Bioflavonoids contribute to good heart health, and combat atherosclerosis, as well as conditions like Alzheimer’s disease. They are found in many of the same foods that contain vitamin C, and these super antioxidants complement and enhance vitamin C’s effect on the body. Fresh fruits and vegetables are generally the top choices for getting plenty of bioflavonoids in a diet. The best are red or sweet bell peppers; strawberries; citrus fruits like oranges, lemons, limes, peaches, nectarines; 33 broccoli; Brussels sprouts; tropical fruits like mangoes and papayas; garlic; spinach; and teas. Food for Thought 1. What problems have you been experiencing lately within your body and your brain? Have you seen any deficiencies listed here that could explain these symptoms? 2. All vitamins are important for some area of the brain - the heart, which pumps the blood that distributes the nutrients; as well as the vitamins and chemical interaction that takes place in order to protect and keep the brain healthy from free radicals. Would a simple multi-vitamin do the trick for you, or are there specific vitamins that would be of better use? (Caution: please consult your health professional before making this decision.) 34 Chapter 5 Minerals That Advance Brain Activity Usually, by the time you reach the age of 30 some of your brain cells have already started to die off as your body reduces the amount of chemicals it has used in the formation and development of the brain. By this time medications; toxins in the atmosphere and in the foods we consume have begun to build up in our bodies; and the stress, poor diet and come illness and inflammation has begun to take its toll on your cells and neuroconnections. These all lead to impaired memory. The decline starts off with mild memory problems - like forgetting where you leave your keys or why you opened the refrigerator. By increasing your intake of essential and trace minerals you may be able to improve your brain's storage and recall functions. Minerals are the chemical elements that your body needs to survive. They also are important in the formation and synthesis of enzymes needed to carry out various different chemical reactions in the body. Your body does not make these minerals, but you can take them in with the food you eat. Different minerals perform different functions within our bodies. For example, minerals help in synthesizing important hormones, and control our heartbeat. Most minerals come from plant food because the plants absorb the minerals from the soil. The best way to get the right amount of minerals is by following wellbalanced diet containing vegetables, fruits, whole grains and different protein sources. These minerals must be present in normal proportion so that body may carry out its normal functions easily. Minerals are present in large quantity in all nuts and grains. As an example, minerals like manganese, chloride, copper, magnesium, molybdenum, sodium and selenium are all found in the nuts in rich amount. Many of these nuts contain high quantities of copper, while salted nuts possess high level of sodium. Different nuts that contain minerals include: Brazil nuts, cashews, amaranth, durum, rye, barley, pumpkin seed, spelt and buckwheat. Most fruits, vegetables and seafood are rich sources of minerals. There are also foods on the market that are fortified with minerals - like beans. All parts of our body are made up of minerals - our hair, bones, organs, muscles and tissues. Because of this minerals are vital to our body’s survival. As in the environment, if we are not careful with our mineral usage, they will start to deplete and then we will be faced with consequences we may not like. In order to 35 be safe, just add some foods like the ones below that are full of the needed minerals to keep our body, and our brain, in tip-top shape! Boron Boron is a trace mineral essential to human health. Trace minerals occur in the soil, in foods, and in your body at much lower levels than the macro-minerals, so they become more easily depleted. It recently has become popular after researchers found that it helps the bones use calcium. Increased boron levels in the soil have been associated with a lower risk of osteoarthritis. When boron deficiencies occur, and deficiencies are much more common than toxicity, it disrupts important metabolic functions and working of the enzymes in the body, like blood sugar regulation; the regulation of iodine for thyroid production; and metabolization of zinc for proper immune function. Deficiencies occur due to a low consumption of fruits and vegetables. In the elderly it can affect bone and calcium metabolism and lead to osteoporosis. If boron occurs in sufficient levels in the soil in which food is grown, the mineral will be in abundance in whole foods, such as apples, grapes, nuts, legumes, and leafy greens. Boron acts on the parathyroid glands to regulate calcium, magnesium, and phosphorus balance. It is also used to prevent bone loss. Some diseases, activities, foods, and drinks can increase your risk of trace mineral deficiency - through sweating and dehydration. Diseases and conditions to watch out for include parasitic infections, ulcers and diverticulitis (with chronic blood loss), liver disease, burns, chronic inflammatory bowel disease, and weak digestion. You need about 1 mg of boron daily from your diet, but 3–5 mg may be more. Calcium Calcium is the fifth most abundant element by mass in the earth’s crust. As a major material, calcium is used in the formation of bones, shells and teeth. Calcium is the most abundant metal by mass in many animals, and is essential for all living organisms. 36 It is involved in enzyme production, and one of the effects of low calcium is memory loss. Calcium improves the formation of neurons and nerve impulses, and plays a role in several processes that affect the brain’s function, including enzyme production. According to The Merck Manual one of the symptoms of hypocalcaemia - too little calcium in the blood, is memory loss. Since memory loss can have many causes, you will need to see a physician to have blood or urine tests completed to determine if you have low blood calcium. He may treat you with intravenous calcium therapy or calcium supplements. Calcium is found in milk, soymilk, many kinds of juices, and many antacids. If you know that your diet is calcium-poor, buy over-the-counter calcium supplements that provide at least 1 g, or 100 percent of the U.S. Food and Drug Administration's recommended daily intake for adults. Vitamin D supplements can increase your body's absorption of calcium, and many supplements add vitamin D to their calcium to help in the absorption. Copper Copper interacts with enzymes in your brain that regulate proper brain function, and coordinates between various cells throughout your central nervous system. This mineral plays a significant role in the electron communication chain, which is one of the major energy-producing pathways in your body. A copper deficiency, according to the United States Department of Agriculture, adversely affects brain function by slowing down energy production. It can cause neurological symptoms, such as irregular muscle coordination, peripheral neuropathy, and diseases of the spinal cord. Copper ions are water-soluble. In significant amounts they can be toxic, but in lower amounts are essential trace elements to all plant and animal life. Copper is found mainly in the liver, muscles and bones. The human body absorbs copper in the gut, then transports it to the liver where it binds to albumine, the most abundant plasma protein that is needed for the proper distribution of bodily fluids in the heart and body tissues. Excess copper is excreted via bile, which carries some copper out of the liver that is not then reabsorbed by the intestine. 37 Because copper is used to help absorb iron, a deficiency of it can produce symptoms similar to anemia - stunted growth, bone abnormalities, osteoporosis, hyperthyroidism, and glucose and cholesterol metabolism problems. An accumulation of copper in the body can cause Wilson’s disease, where it manifests itself as neurological or psychiatric symptoms, and liver disease. Iron According to The Linus Pauling Institute, iron is a mineral necessary for healthy brain and nerve function. Some research has indicated that iron deficiency anemia in children has been linked to poor cognition and poor achievement in school. Iron is responsible for the production of the chemicals in the brain that are essential to restoring memory. Studies have shown that people with an iron deficiency do not score as well on memory exams as those who do not have the iron deficiency. Iron is responsible for improving the brain's production of chemicals like dopamine and serotonin, the “feel good” chemicals in the brain. These two chemicals are essential for restoring faulty learning and memory. A study by The American Physiological Society has concluded that women with an iron deficiency performed lower on memory exams than women with healthy levels of iron. Iron is essential for life. Not only is it found in proteins and enzymes, but is responsible for cell growth and transporting oxygen throughout the body. Too much or too little iron in your system can result in serious health issues. The recommended dietary allowance (RDA) issued by the Institute of Medicine of the National Academy of Sciences to meet nutrient requirements of 98% of healthy individuals is: Women, age 18-51: 18 mg/day Pregnant women: 27 mg/day Breastfeeding women: 10 mg/day Women, over the age of 51: 8 mg/day Men, age 19 and older: 8 mg/day 38 Iron can be found in two forms, heme or nonheme. Heme iron is found in red meats, fish and poultry (animal foods). Nonheme is found in plants, such as beans and lentils. Iron fortified foods are fortified with nonheme iron. The typical healthy adult will absorb 10-15% of their RDA from the food they eat. If the iron storage in their body is low they will absorb more. In addition, the type of iron they absorb (heme or nonheme) will make a difference as well. Iron deficiency anemia will occur when the storage is too low, and the amount consumed does not meet the minimum RDA. According to the World Health Organization, iron deficiency is the number one nutritional disorder in the world. “As many as 80% of the world's population may be iron deficient, while 30% may have iron deficiency anemia.” The most at risk of this are pregnant women, women with heavier than normal menstrual periods, those with renal failure, and those with problems absorbing iron - like from a gastrointestinal disorder. Those who exercise intensely also are at greater risk, as well as vegetarians, due to a greater turnover of red blood cells (they need to take in 30% more iron that the RDA). Symptoms of iron deficiency include: Feelings of weakness and fatigue Slower performance in work or school activities Inability to maintain body temperature Lowered immunities Inflamed tongue (glossitis) For those who are unable to get adequate iron through their diet, supplementation may be necessary. It is important to be evaluated by a doctor before taking iron supplements in order to get a prescription that will be appropriate to individual needs. Iron pills are taken to correct an iron deficiency. In addition to iron in supplement form, you can obtain iron through various food sources. Good iron choices include beef and other red meats, chicken, shrimp, tuna, blackstrap molasses, raisins, potatoes, beans, cereals and lentils. If you eat a meal containing nonheme iron, avoid the use of drinks such as tea, coffee or wine (that contain tannins), because they will decrease the absorption of the iron. An iron overload could occur when the body is storing excess iron. If this should happen the liver and heart are the storage areas, and it could lead to cirrhosis of the liver and/or heart failure. People with the genetic disease hemochromatosis, and people with blood disorders that require frequent blood transfusions, are at greatest risk. 39 Lithium Lithium has been used to help people with mental problems to help calm them from violent, suicidal or criminal tendencies. It has also been an aid for drug abusers. Many people call it the drug for “crazy people”, but it actually does a lot to help the brain by reducing brain shrinkage and memory loss. The mineral lithium naturally is found in tomatoes, and is added to the water supply of many communities. It is rare to find it in supplement form or vitamins, or in health food stores for that matter. High doses of lithium carbonate are prescribed for patients with bipolar disorder. Small doses of lithium orotate and lithium aspartate can be found over the counter in some health food outlets. Numerous studies have found that a common mineral heals the brain by stimulating the growth of new brain cells and protecting brain cells from every known neurotoxin. It has been shown to reduce the incidence of violent crime, homicide, suicide, and drug addiction, while preventing the brain shrinkage and memory loss that otherwise occurs naturally with age, as well as helping people with alcoholism, Alzheimer’s disease, depression, Parkinson’s disease, stroke, cluster headaches and traumatic brain injury. The (now late) German orthomolecular physician, Dr. Hans Nieper, stated that lithium orotate is transported more effectively inside cells, which is more effective in lower doses than the prescription form of lithium carbonate. A 10-year study out of Texas found that when small doses of lithium (70-170 micrograms per liter) was added to the tap water of communities the percentage of violent crimes and suicide decreased significantly. A similar Japanese study supported these findings. The amount of lithium in the water was approximately ½ of 1% of the amount taken by bipolar patients, and these findings are spurring on advocates of adding lithium to tap water. One advocate, Dr. Jonathan Wright, author and found of the Tahoma Clinic in Renton, Washington, and member of the medical advisory board for Life Extension Foundation, a non-profit organization, began working with lithium in the 1970s while conducting research at a VA hospital. He found that a number of alcoholics, when given lithium, not only drank less alcohol, their aggressive behavior and violence also was reduced. The subjects were less moody, slept better, and in general were calmer and happier. Lithium also seemed to protect the brain from the damaging effects of alcohol, reducing the hangover the morning after. Although Wright did caution that the drug would have to be taken regularly, prior to a night of overindulgence, to protect brain cells. You can’t just pop a “morning after” pill to get the same effect. 40 Wright found that children of alcoholics often exhibit the same behavior problems of their parents, and craved sweets, suffered from depression and often became alcoholics themselves. He began administering low doses of lithium to the children and soon found calmer children with less behavioral problems. In 1999 Wright began using 20 mg/day of elemental lithium (in the orotate form) himself to protect his brain and prolong his own mental health. He has no family history of mental disorder, nor was experiencing problems himself. He was just so convinced of the positive effects of lithium on the brain that he put his money where his mouth was. The point he decided to take this step was after an article appeared in the British medical journal, The Lancet, that reported findings of a significant increase in brain volume (billions of additional brain cells) was found in subjects after just four weeks of high-dose lithium therapy. This report actually changed the way neuroscientists thought at the time, that we were born with a finite amount of brain cells, and when they died out our minds began to decline. They were finding that brain cells could be replenished, and lithium seemed to help that process along. According to Wright, there has been an “avalanche of research” about lithium since 1999. It has been shown to be a “wonderful neuroprotective agent from any type of toxin there is.” This protective brain mechanism is so strong that, according to Wright one respected lithium researcher said that it “verges on malpractice to prescribe any psychotropic medication (antidepressants, antianxiety meds, and sleeping pills) without lithium to protect the brain.” In turn, studies have found that if the blood supply is suddenly cut off to the brain, like from a stroke, brain cells suffer much less damage if the stroke victim has been taking lithium prior to the stroke (It does not work after the damage has already occurred.). In over 30 years, Wright has encountered only two or three people who have had a possible reaction to a dose of 20 mg/day or less: they thought it might have caused a slight tremor — which went away when the lithium was discontinued. On the other hand, he’s had dozens of patients’ report that their benign tremor improved on low dose lithium Wright pointed out that every patient is different, and it is wise to also take fish oil and flax seed oil if one is taking lithium to prevent lithium toxicity, but in over 30 years of working with patients and lithium he had only encountered two or three people who experienced negative reactions, slight tremors. Dozens of patients, on the other hand, reported that benign tumors had improved on low doses of lithium. Wright did caution that no one should begin a regiment of higher doses of lithium (over 55-mg. per day of elemental lithium; or 11 tablets of lithium orotate or aspartate containing 5 mg per tablet) without first getting a blood test to check for 41 toxicity. Lithium toxicity symptoms include tremors of the hands, elevated blood pressure and flu-like symptoms. Magnesium Magnesium is an important mineral because it protects the brain from neurotoxins that can interfere with cognitive and memory ability. In 2004, researchers at the Massachusetts Institute of Technology discovered a link between memory loss and low magnesium intake. They concluded that brain cell growth in both children and adult brains, requires adequate dietary magnesium. A later study, conducted in February 2010 at Beijing's Tsinghua University, in cooperation with MIT and other institutions, reported that a synthetic magnesium supplement improved memory functions and prevented memory loss in laboratory animals. "Magnesium is an important brain nutrient because it protects the brain from neurotoxins," says City Island, N.Y.-based Carolyn Dean, ND, MD, author of The Miracle of Magnesium. "Some enlightened surgeons give extra magnesium to their patients before and during surgery, especially brain surgery, for this reason," she reported in an interview with WebMD. The dosage for protecting the brain in general is 300 milligrams one to three times a day. According to Dean, nuts, seeds, dark leafy greens, and whole grains have magnesium, but most other foods have little, she says. "Cooked and processed foods also lose a lot of magnesium making it a very deficient mineral." Magnesium is sometimes described as an "antistress" mineral, and is also vital for the production and transfer of nerve impulses, in muscle contraction and relaxation, in protein synthesis, and in many biochemical reactions. Researchers have found that magnesium stimulates synapses, the junctions between neurons in the brain that transmit nerve signals. Several studies have noted that low levels of magnesium are at the top of the most common dietary deficiencies in the world, especially among older people, and there is some speculation that magnesium deficiency may be linked to the development of Alzheimer's disease, as well. 42 An average diet usually supplies about 120 mg of magnesium per 1,000 calories (or an estimated daily intake of about 250 mg). This is not an adequate level of magnesium for most people. The current Recommended Daily Allowance (RDA) for magnesium is about 350 mg for men and 300 mg for women, increasing to about 450 mg during pregnancy and lactation. The minimum is also expressed as about 6 mg per 2.2 pounds of body weight, but there are many experts who feel that the RDA should be doubled to about 600 to 700 mg daily. Dietary sources of magnesium include green leafy vegetables, nuts, whole grains, soybeans, milk, dairy, potatoes, seafood and certain fruits. Note: A new supplement, Magnesium l-threonate (MgT), according to a study in the journal Neuron, increases the level of magnesium in the brain and can significantly improve memory and learning. It is not the traditional magnesium, which has trouble getting past the necessary blood-barrier, where MgT does not. Further research is necessary to measure its effect in humans, however MgT is available now for those who want to try it (after first consulting with your health professional). Phosphorus Phosphorus is present in every cell in your body, and is especially concentrated in your brain. It helps maintain healthy brain function and aids the central nervous system health by helping nerve cells communicate with one another, and to activate receptor sites that stimulate neurotransmitter production. Neurotransmitters, such as dopamine and serotonin, regulate many body functions, including emotions, energy metabolism, and mood. Low levels of phosphorus in the brain have been linked to anxiety disorders and muscle tremors. Phosphorus can be found in the environment most commonly as phosphates. Phosphates are important substances in the human body, because they are a part of DNA materials and they take part in energy distribution. Phosphates can also be found commonly in plants. Humans have changed the natural phosphate supply radically by the addition of phosphate-rich manures to the soil, and by the use of phosphate-containing detergents. Phosphates were also added to a number of foodstuffs, such as cheese, sausages and hams. 43 Too much phosphate can cause health problems, such as kidney damage and osteoporosis. Phosphate shortages can also occur. These are caused by extensive use of medicine. Too little phosphate can cause health problems. Phosphorus in its pure form has a white color. White phosphorus is the most dangerous form of phosphorus that is known to us. When white phosphorus occurs in nature this can be a serious danger to our health. White phosphorus is extremely poisonous and in many cases exposure to it will be fatal. White phosphorus can cause skin burns. While burning, white phosphorus may cause damage to the liver, the heart or the kidneys. In most cases people whom have died of white phosphorus exposure had accidentally swallowed rat poison. Before people die from this exposure they often experience nausea, stomach cramps and drowsiness. Phosphates have many effects upon organisms, mainly negative consequences by the emission of large quantities of phosphate into the environment due to mining and cultivating. During water purification, phosphates often are not removed properly, so that they can spread over large distances when found in surface waters. It is because of these human interventions that the natural concentrations of phosphorus have been rearranged. The increasing phosphor concentrations in surface waters raise the growth of phosphate-dependent organisms, such as algae and duckweed. These organisms use great amounts of oxygen and prevent sunlight from entering the water. This makes the water fairly inhabitable for other organisms. This phenomenon is commonly known as eutrophication. Phosphate is a dietary requirement, the recommended intake is 800 mg/day, a normal diet provides between 1000 and 2000 mg/day, depending on the extent to which phosphate rich foods are consumed. Potassium/Kalium Potassium is essential for the proper functioning of the heart, kidneys, muscles, nerves, and digestive system. It keeps your electrolytes in balance and improves nerves and nerve impulses. It is an essential mineral for all living cells. A depletion of the potassium supply can cause cardiac problems, and mental disconnect. Usually you can get enough potassium in your diet, however there are a number of things that can remove it from your body - diarrhea, vomiting, drugs, diuretics (water pills), kidney disease or gastrointestinal diseases. Potassium supplements are then prescribed to replace the potassium lost and prevent potassium deficiency. 44 Because potassium and sodium are chemically very similar, it took a long time before people understood there was a difference. Potassium is not sodium, nor it is salt. It is one of the top ten most common elements found in the human body, behind sulfur, chlorine, calcium and phosphorus. Potassium is found in especially high concentrations within plant cells, and in a mixed diet it is mostly concentrated in fruits. The high concentration of potassium in plants, associated with comparatively low amounts of sodium there, resulted in potassium's being first isolated from potash, the ashes of plants, giving the element its name. For the same reason, heavy crop production rapidly depletes soils of potassium, and agricultural fertilizers consume 95% of global potassium chemical production. It is important in brain and nerve function, and in influencing the balance between cells and fluid. It can be detected by taste because it triggers three of the five types of taste sensations, according to concentration. Dilute solutions of potassium ions taste sweet, allowing moderate concentrations in milk and juices, while higher concentrations become increasingly bitter/alkaline, and finally also salty to the taste. The combined bitterness and saltiness of high-potassium solutions makes high-dose potassium supplementation by liquid drinks hard to swallow. Potassium is also important in preventing muscle contraction. A shortage of potassium in body fluids may cause a potentially fatal condition known as hypokalemia, typically resulting from vomiting, diarrhea, and/or increased diuresis. Deficiency symptoms include muscle weakness, ECG abnormalities, decreased reflex response, and in severe cases respiratory paralysis and cardiac arrhythmia. Foods rich in potassium include parsley, dried apricots, dried milk, chocolate, nuts (especially almonds and pistachios), potatoes, bamboo shoots, bananas, avocados, soybeans, bran, fish, meat and vegetables. It comes in oral liquid, powder, granules, effervescent tablets, regular tablets, extended-release (long-acting) tablets, and extended-release capsules. It usually is taken two to four times a day, with or immediately after meals. Supplements of potassium in medicine are most widely used in conjunction with loop diuretics and thiazides, classes of diuretics that rid the body of sodium and water, but have the side effect of also causing potassium loss in urine. A variety of medical and non-medical supplements are available. Take all forms of potassium with a full glass of water or fruit juice. Potassium may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away, such as an upset stomach, vomiting or diarrhea. 45 Potassium is excreted through the kidneys. Disorders that slow down the functioning of the kidneys can result in a condition called hyperkalemia. These symptoms could be due to excessive sweating, vomiting, diarrhea, eating disorders, certain medications, and kidney disease. A deficiency of potassium is rare in healthy individuals because it is present in sufficient quantities in fruits, vegetables, meat and fish. People who suffer from kidney disease may suffer adverse health effects from taking in large quantities of potassium. A buildup of potassium in the blood could trigger a fatal heart arrhythmia. If you experience any of the following symptoms, call your doctor immediately: Mental confusion Listlessness Tingling, prickling, burning, tight, or pulling sensation of arms, hands, legs, or feet Heaviness or weakness of legs Cold, pale, gray skin Stomach pain Unusual stomach bulging Black stools Selenium Your brain cells require 10 times more oxygen than the rest of your body. According to the Franklin Institute, selenium helps your memory by clearing toxins that impair your brain's functions. This trace element is a powerful antioxidant that bonds with vitamin E and scavenges free radicals and heavy metals in your brain. Only a small amount is needed for good health. Selenium's removal of brain toxins improves the blood flow to capillaries, nerves and synapses that carry brain signals. This helps the brain restore its normal balance and makes room for the minerals that the brain needs for memory to function. As an antioxidant, selenium removes toxins from the brain and that makes room for the minerals your brain needs to prevent memory loss. It is incorporated into proteins to make selenoproteins, which are important antioxidant enzymes. The antioxidant properties of selenoproteins help prevent cellular damage from free radicals, the harmful but natural by-products of oxygen metabolism that may contribute to the development of chronic problems, like heart disease. They also help to regulate thyroid function, and play a role in the immune system. Selenium can be found in plant foods mostly, depending on the amount of selenium inn the soil the plants grow in. It can also be found in some meats and 46 seafood. Animals that eat grains or plants that were grown in selenium-rich soil have higher levels of selenium in their muscle. Human selenium deficiency is rare in the U.S. but is seen in other countries, most notably China, where the concentration of selenium in the soil is low. There is scientific evidence that selenium deficiency may contribute to the development of a form of heart disease, hypothyroidism, and a weakened immune system, although selenium deficiency alone does not usually cause illness, it just makes the body more susceptible to illness. Three specific diseases have been associated with selenium deficiency: Keshan Disease, which results in an enlarged heart and poor heart function, occurs in selenium deficient children. Kashin-Beck Disease, which results in osteoarthropathy Myxedematous Endemic Cretinism, which results in mental retardation Sodium Potassium and sodium are electrolytes, meaning they contain free ions that give them the ability to conduct electricity. The electrolyte, or potassium-sodium balance in your body is related to nerve connectivity and the ability of your nervous system to activate target cells rapidly. In a chemical reaction, electrolytes are substances that become ions when immersed in liquid, and are then able to conduct electricity. Electrolytes are present in the human body, and the balance of the electrolytes in our bodies is essential for normal function of our cells and our organs. Potassium is primarily located inside of your body's cells while calcium is located outside. This creates a balance, or membrane potential, between the two minerals, which are essential for nerve impulses, muscle contraction, and heart function. Doctors commonly test for electrolytes when testing for sodium, potassium, chloride and bicarbonate in blood tests. Sodium is the major positive ion (cation) in fluid outside of cells. When combined with chloride, the resulting substance is table salt (NaCo2). Excess sodium is excreted in the urine. 47 Sodium regulates the total amount of water in the body, and critical body function is dependent on the transmission of sodium into and out of individual cells. Many processes in the body, especially in the brain, nervous system, and muscles, require electrical signals for communication, and the movement of sodium is critical in generation of these electrical signals. Too much or too little sodium therefore can cause cells to malfunction, and extremes either way in the blood sodium levels can be fatal. Hypernatremia, or increased sodium in the blood occurs whenever there is too much sodium in relation to water. Causes of this may include kidney disease, too little water intake, and loss of water due to diarrhea and/or vomiting. Hyponatremia, or a decreased concentration of sodium occurs whenever the amount of body water relative to sodium is too little. This happens with some diseases of the liver and kidney, in patients with congestive heart failure, in burn victims, and numerous other conditions. Zinc Zinc plays an important role in the neurological functions of the brain. Studies have shown that when given zinc-enriched snacks to adolescent girls, they were able to score higher on visual memory tests. Zinc can be found in red meat, nuts, beans, whole grains and dairy products. Zinc contains many hidden health benefits and is essential to the smooth running of almost every aspect of the human body. For optimum health, make sure zinc is a daily part of your diet. Zinc is key to high cognitive function in more ways than one. Studies have shown that consuming zinc increases cognition and memory. Initially, the mineral teams up with vitamin b6 to ensure that neurotransmitters in your brain properly function. In addition, high concentrations of zinc are found in the mossy fiber system of the hippocampus, which is the brain’s center of thought and memory. Supplemental zinc can be especially useful to improve the cognition of people recovering from injury, as the body diverts zinc from the brain to help heal bodily trauma. Food for Thought 1. Minerals for our bodies are normally found in the soil, so plants are the best source for them. Do you see a reason to increase the amount of vegetables in your diet? 48 2. The value of adding minerals to your normal supplement regime is evident, don’t you agree? Chapter 6 Spice Up Your Memory Worldwide, traditional healers have, throughout time, prized select herbs to help people keep healthy and retain their mental and physical fitness. So far, the current scientific research on herbs to enhance memory is still being studies. As with pharmaceuticals, no herbs have yet been proven to cure dementia or to prevent it from developing, however, some experts are optimistic about certain herbs and their potential. One such expert is Con Stough, Ph.D., a professor of neuropsychology at the Brain Sciences Institute at Swinburne University in Melbourne, Australia. Stough pointed out that, while pharmaceuticals tend to have a single action, herbs can have numerous, often synergistic actions. Because Alzheimer’s disease and other dementias have multiple causes, this herbal multitasking is important. Even more important, these herbs are natural elements, and have fewer side effects. Many people are turning to herbs for memory improvement to stimulate and keep their brains sharp and focused. Herbs have been perceived and used for centuries by healers as the natural and safe way to maintain the level of brain function and improve memory. The brain is an extremely complex organ that controls both the short and long term memory in addition to all the body’s organs and systems. Most times people don’t become aware that they are having lapses of memory more often, and when they do realize it they start to worry that they be having have some serious health problem. Almost everyone experiences lapses of memory at some point in their life, and not all of them are a cause for concern. Some of the causes for poor memory may well respond positively to using herbs for memory improvement. 49 Short-term memory accounts for things that have happened, or what we have done in the recent past - like what we had for dinner last night, or did we remember to switch the cooker off when we left the house? One of the most common causes of short-term memory problems in a perfectly healthy individual is simply that they have been disinterested and switched off. They are not paying attention, have lost focus, or simply are not interested in paying attention. This type of short-term memory lapse comes down to selfdiscipline and herbs for memory improvement are unlikely to help. Short-term memory can be affected by many different medical conditions - such as dementia and Alzheimer. They are perceived as being age related, but can occur in patients of any age. Herbal remedies are often used in the early stages of these diseases, as they are believed to be beneficial in slowing the progress. Although initially it is usually the short-term memory, these conditions can progressively destroy the long-term memory as well. Many physical or mental illnesses can affect short-term memory. A combination of drugs, inflammation, pain and other symptoms can affect levels of concentration and the ability to take in and retain information. This usually resolves once normal health is resumed. Herbs for memory improvement may help to improve concentration and relieve pain in these cases, making it easier to retain information. Long-term memory is a combination of the things we have experienced, seen or learned over our lifetime. These things the brain thinks are important enough to keep and file away for later retrieval. Some memories do fade over the years, particularly if it was an unpleasant experience that we try to block out anyway. The memories that do last are the ones that have meaning to us, or the things we have learned. As with short-term memory loss, there are several reasons why our memories become impaired, and using herbs for memory improvement has proven to be beneficial in many instances. There is a whole range of recommended herbs for memory improvement, and herbalist will provide detailed advice and guidance as to the right herbal remedy for an individual’s circumstances. In general the most popular herbs used are: Ginkgo biloba Sage Giloy Brahmi These are only a few of the most popular herbs for memory improvement. They are safe to use and can be taken as prescribed for long-term preventative use. 50 When you think of “antioxidants” you usually think of vegetables, fruits and even chocolate, but how often do you think of spices as being beneficial brain food? The food distributor, McCormick, set out to promote “seven super spices” that are on the level with fruits and vegetables when it comes to antioxidant benefits. Aside from adding color and flavor to our food, herbs and spices can protect our brain cells as well. For example, garlic has been found to lower cholesterol and blood pressure; Ginger may lessen the pain of arthritis; and several herbs and spices are believed to have cancer-fighting properties. Because of their strong antioxidant properties, herbs and spices may help protect our brain cells from the wear and tear of brain aging. Examples of some of the more potent spices include oregano, vanilla, cinnamon, parsley, basil, and pepper. Many people have a home garden of herbs and spices, which are even more beneficial than those found in a can or jar. Chefs and nutritionists have recommended spices and herbs to add flavor to food without adding the fat, salt or sugars. Now studies involving the antioxidant richness of spices suggest using these flavor enhancers to add more health as well. "It's the ultimate in good nutrition news when adding a favorite ingredient increases the health benefits of the foods we're already enjoying," says Dr. Wendy Brazilian, head nutritionist at McCormick Science Institute, an independent research organization supported by McCormick & Company. Research has shown that antioxidants are substances that may protect cells against the effects of free radicals -molecules produced when your body breaks down food, or by environmental exposures like tobacco smoke and radiation. Antioxidants can protect you against heart disease, cancer and other diseases. Antioxidants include beta-carotene, lutein, lycopene, selenium and vitamins A, C, and E. Research has also found that herbs and spices protect unique properties that possibly could reduce inflammation, a precursor to many chronic diseases such as heart disease, Alzheimer’s, and allergies. They are exploring the possibility of boosting metabolism to promote weight loss as well. Botanically, spices and herbs are classified as both fruits and vegetables. Because they do not possess the water content of most fresh produce, they offer higher levels of the antioxidants. In addition, they are rich in phytonutrients, such as carotenoids, flavonoids and phenolics that all have healthful properties. 51 Researchers are looking into the effects of heat and preparation techniques and there is no official answer on whether or not certain compounds or nutrients are altered when exposed to heat or other practices. According to Dr. Bazilian, some research has suggested that heat may actually enhance the ability of the body to absorb and use as a nutrient certain compounds, while others may be potentially decreased. "It is likely that we will discover there are great benefits to be had from including herbs and spices along with other health-promoting Superfoods, regardless of preparation techniques." Adaptogenic herbs Stress is the number one killer of brain cells. According to The American Academy of Family Physicians in Kansas City, Mo., approximately two-thirds of all office visits are for stress-related complaints. Stress, however, is not a disease, but simply a fact of life. Although the triggers for stress have changed over the years, human physiology has remained the same. Our bodies still respond to threats, known as the “fight or flight” syndrome, by secreting hormones that change our physiology and enhances our ability to run away or defend ourselves. This response includes stimulating the adrenal glands and the sympathetic nervous system. This response also results in increased respiratory rates, higher blood pressure and blood sugar levels, and an increased heart rate. At the same time, there is a decrease in digestive secretions. In the cases where stress is acute the situation is usually resolved in a quick manner and the system returns to normal. If the stress is prolonged and chronic, it can become harmful to the body and the brain cells. Adaptogenic herbs have been found to lower the negative effects of stress to the body and have a positive influence on stress response, mental function, and cognition. The list of plants with adaptogenic properties is quite long simply because of the term's broad definition. We have tried to include as many here as possible. Many of these traditional herbs, established by hundreds or thousands of years of use, are now beginning to prove themselves under modern medical scrutiny. Studies are finding that many have far-reaching and beneficial properties for all areas of health. Even though modern stresses differ from those of the past, the body's reactions remain the same. Adaptogens may hold the key to living well in the next century. Despite these herbs' normalizing qualities, it is best to urge customers to consult a medical professional before using adaptogenic products. 52 Qualities to have been found in adaptogenic herbs include: Antioxidant activity Liver protection and antitoxin activity Improved blood-sugar metabolism Less craving for alcohol or sugar Improved immune resistance Increased energy and stamina Improved muscle tone Increased strength Faster recovery Better focus and concentration Less anxiety Better sleep Better motivation and productivity A feeling of well-being Better moods Adaptogenic herbs with the highest properties for memory protection are listed below with an asterisk (*) in front of the name. Tips & Warnings Most herbal remedies are inexpensive to moderately priced, however, you may find dried herbs and teas offer a greater savings over capsules and tablets. Even better - grow your own herb garden. Combine herbs with regular exercise to maximize the benefits of these natural remedies and keep yourself healthy. Exercise increases blood flow, which can boost your memory. Keep in mind that herbal remedies aren't intended to replace the care of a physician when you have a life-threatening emergency or injury. If you experience severe memory loss, confusion, loss of consciousness or unexplained dizziness, contact your doctor immediately or go to the hospital. Consult MayoClinic.com to learn how educate yourself about alternative medicine claims (see Resources below). Learn how to assess those claims before you make your treatment decision. Here are some of the most important herbs and spices that help improve your memory and overall brain health: *Ashwagandha Also known as Indian ginseng or winter cherry, ashwagandha has been proven in two scientific studies to enhance cognition and improve memory. It acts as a 53 stress buster as well as having the ability to revitalize the brain. It helps by keeping the brain active and calm, and is mainly used in soothing the brain and helping to “keep your cool” for better performance. It also increases the memory power by enhancing the brain and its nerves. *Astragalus One of the more famous tonic herbs from China, Astragalus (Astragalus spp) is a traditional Chinese medicine said to detoxify the blood and spleen, and aid the defensive chi. Astragalus is often used in combination with other herbs to enhance recovery following an illness or prolonged stress, and to boost vitality. It is said to protect and enhance the functioning of distressed organs. Numerous studies have found that astragalus enhances the immune system by increasing the natural killer cell activity and increasing T-cell activity in patients with compromised immune systems. *Bacopa Monniera Ayurvedic doctors in India have used this Asian herb for centuries as one of the natural vitamins for memory improvement and concentration, and scientific research seems to support this claim. Studies indicate bacosides (the natural phytonutrients in this herb) may support brain transmitters during memorization, among other effects, as well as enhance intellectual activity. Bacopa is a marshy plant that grows in the Middle East, Florida and Hawaii. It produces antioxidant properties, and according to some recent studies, may improve higher cognitive functions such as learning and memory. Bacopa contains memory chemicals that help your body make more GABA, a crucial neurotransmitter that calms your mind and filters out distractions. When you don’t make enough of it, your thinking gets cloudy and you have trouble concentrating. It also repairs damaged nerve cell connections so your brain can send and receive messages more easily. Bacopa is used to improve concentration, retention and recollection. It can also be useful in relieving stress and anxiety and lowering blood pressure. It has been used for Alzheimer's disease, improving memory, anxiety, attention deficit-hyperactivity disorder (ADHD), allergic conditions, irritable bowel syndrome, and as a general tonic to 54 fight stress. At least 14 recent studies confirm bacopa improves memory and boosts retention of new information. In one study, researchers found people who took bacopa did a better job of recalling lists of 15 words after they were read aloud. It also helps so a person has an easier time blocking out distractions. Another way bacopa improves memory is to soothe frazzled nerves and help you handle stress better. Stress affects your memory, making you more forgetful and even accident-prone. So reducing stress actually boosts your mental performance! Many people who take bacopa regularly notice they feel less stressed and even sleep better. One study showed bacopa lowered anxiety levels by about 20 percent. As you can see, bacopa can sharpen your memory, improve your concentration, and bring you many other health benefits. Despite this, you’d have a hard time finding this well-researched herb in any memory supplement. Con Stough, Ph.D., a professor of neuropsychology at the Brain Sciences Institute at Swinburne University in Melbourne, Australia, who has done much of the research on bacopa, said the herb has several anti-Alzheimer’s actions. “There is a growing consensus indicating that bacopa and particularly CDRI08 [a special standardized extract] improve memory and cognition in non-AD patients.” In the largest study, 107 healthy adults took either a placebo or a bacopa extract (two 150-mg tablets a day) for three months. Those who faithfully took the herb performed significantly better on memory tests. A 12-week study of healthy adults showed bacopa improved learning and memory and reduced anxiety. Bacopa induces a sense of calm and peace and improves cognitive function. In ayurvedic traditional medicine, brahmi is used as a rasayana, a traditional formula that includes spices and honey to make a palatable mixture. The effectiveness of brahmi is increased by simultaneous supplementation with inositol and/or a B-vitamin complex. Bacopa might increase certain brain chemicals that are involved in thinking, learning, and memory. Some research suggests that it might also protect brain cells from chemicals involved in Alzheimer's disease. For best results, adults should take 3,000 milligrams one or twice daily. It may take four weeks to see an improvement. In capsule form bacopa is best taken at the beginning of the day and again in mid to late afternoon, or before doing meditation or yoga. This plant is available as a bacoside extract in tablet form. 55 Basil Basil, Ocimum sanctum, was originally a native plant of India and its use only spread outward to Europe and the West since the sixteenth century. Ocimum sanctum, or Tulsi as it is known in Hindu, is used in traditional in religious ceremonies and in ayurvedic medicine for common colds, headaches, stomach disorders, inflammation, heart disease, various forms of poisoning, and malaria. Basil is one of the best-loved culinary herbs for good reason. It helps to improve appetite, and like other herbs in the mint family it settles the stomach and is a natural disinfectant. Basil is known for its diverse varieties, many with distinct aromas in the essential oils in the leaves. The strong clove scent of sweet basil comes from eugenol, the citrus scent of lemon basil and lime basil comes from a higher portion of the aldehyde citral and limonene, which gives actual lemon peel its scent. African blue basil has a strong camphor smell because it has camphor and camphene in higher proportions. Anise basil contains anethole, the same chemical that makes anise smell like licorice. All basils are antibacterial and act as good insect repellents, and as Culpepper noted, “Being applied to the place bitten by venomous beasts, or stung by a wasp or hornet, it speedily draws the poison to it” Whatever culinary delight you are planning, whether it is pesto or a simple tomato and basil sandwich, the burst of aroma that emanates from fresh basil has an almost magical ability to make you feel happy for no apparent reason. A pot of basil growing in the kitchen window will not only provide zest to winter dishes, it will inspire dreams of spring during the cold, dreary days of winter. Basil oil is a light greenish-yellow color and has a sweet, peppery scent. Basil oil has the stimulating properties of mint, and is in the same plant family. Basil is a great oil to burn in aroma lamps while working or reading; it helps you to concentrate and uplifts your mood. Basil has no known side effects, and the uses of this herb are only limited by your imagination. The fresh picked leaves make a stimulating and refreshing tea, and in the summer use them on sandwiches just as you would a leaf of lettuce. Crush the leaves and rub a bit on your skin to make a handy remedy for insect bites when you are out tending to the summer garden. To remove a wart, rub 56 basil leaves on the nub daily and cover with a bandage. Diffuse basil essential oil in an aroma lamp to lift depression and clear the air in a stuffy room. Blessed Thistle The word thistle is the common name of a group of flowering plants that protect themselves from herbivores by possessing sharp, prickly flowers and parts of the leaves. Blessed thistle herb has been known to improve circulation in the body, to purify blood and to eliminate toxins. It can act as nourishment for the overall brain. Thistle contains tannins, with help prevent inflammation. It also aids in the healing of diarrhea and cough. Do not take blessed thistle if you are pregnant; allergic to ragweed, chrysanthemums, marigolds, daisies, or other members of this plant family; or have stomach problems. Cacao Beans Cacao beans, cocoa beans, or in other words - chocolate! Although not the kind with all the gooey butter and additives, chocolate has been known for centuries to have the power to enhance memory and create a “blissful” feeling. Chocolate and cocoa contain a high level of flavonoids, specifically epicatechin, which may have beneficial cardiovascular effects on health. Chamomile Chamomile is widely used to treat such gynecologic complaints as menstrual cramps and sleep disorders related to premenstrual syndrome (PMS). It has been found to be a fairly strong antispasmodic and anti-inflammatory, and is particularly effective in treating stomach and intestinal cramps. Chamomile also can help a child fall asleep, and calms adults as well. It’s relaxing effects do not interfere with activities such as driving a car or 57 completing difficult tasks, as is the case with prescription sedatives. Chamomile is an ideal choice for those with ulcers or other stomach problems, muscle pain that results from stress and worry. The calming effect of chamomile, along with the anti-inflammatory and as a rich source of luteolin, an important flavonoid for brain health, makes it excellent in tea and other drinks. Cinnamon A doctor friend recommends cinnamon for a number of reasons, most importantly for regulating sugar levels, lowering cholesterol and keeps you focused. A recent study found that cinnamon speeds the rate at which your brain processes visual cues. Cinnamon has one of the highest antioxidant levels of any spice – and even more than many foods. There are as many antioxidants in 1 teaspoon of cinnamon as a full cup of pomegranate juice or ½ cup of blueberries. Chewing cinnamon gum may keep your brain sharp, so chomp away to a better memory. Cinnamon's anti-inflammatory properties can alleviate the symptoms of arthritis, and inhibits the growth of food borne bacteria, thereby acting as a food preservative. Club Moss The dry, finely powdered spores of club moss are used to promote healing by drying excess moisture that can cause skin irritation and itching in eczema, much like cornstarch or colloidal oatmeal. These antibiotic spores are non-toxic, unlike the leaves and stems of the plant that contain two poisonous alkaloids, lycopodine and clavadine. Club moss was used as a whole herb in traditional Chinese medicine, and in homeopathic amounts in the West. An ingredient in the Traditional Chinese Medicine remedy Qian Ceng Ta, club moss has been used for centuries to treat fever and inflammation. Preliminary research on in China on one of the active constituents of club moss, called huperzine a (HupA.), which has shown significant improvement in the cognitive function in patients with mild to moderate vascular dementia. This had led to its popular use as a memory enhancement supplement. Club Moss Side Effects: Safe in recommended amounts. Not to be used while pregnant. Not for long-term use. 58 Preparation Methods & Dosage: Dried spores as a powder. Most commonly found in extract and capsule form, but is suitable as a tea. Typical dosage: 50 to 100 micrograms in capsules daily. Curry/Turmeric Want to spice up your life in more ways than one? Add curry to your meals! It is a statistical fact that those who live in South Asian countries, where the use of the curry to season foods is common, have a lower incidence rate for Alzheimer’s disease. Is it a coincidence? Curry powder is a combination of spices, and it varies by country, but the one ingredient that is common to all curried mixtures is "turmeric." Curcumin is the substance that gives the spice turmeric its yellow color and is also responsible, at least in part, for some of the health benefits of curried dishes. Scientists have long known that curcumin is good for improving memory. Now they know why. The spice is a powerful antioxidant that has been shown to protect nerve cells. One theory is that the spice acts as a “scavenger,” attacking free radicals that harm the nerve cells involved in forming memories and mental functions. This information can be very valuable in the search for a cure to mental diseases like Alzheimer’s and Parkinson’s. “Since it has both neuro-protective and memory-enhancing properties, it may be unique in treating clinical disorders associated with the loss of nerve cells and cognitive abilities,” say researchers at the Salk Cellular Neurobiology Laboratory, one of the world's leading research centers. In the search for ways to treat individuals who have suffered traumatic brain injury (TBI) and stroke, researchers at the Salk Institute are studying a curcumin-derivative compound, known as CNB-001. Salk researchers have found that CNB-001 improves dramatically both “behavioral and molecular deficits of ischemic stroke and TBI in animals.” The compound has shown to be extremely neuro-protective in all of the studies, while enhancing memory in normal animals. It has shown significant results in protecting nerve cells that occur in brain injuries, as well as age-related neurodegenerative diseases such as dementia. Other health benefits that have been associated with ingredients in curry include: 59 Due to its powerful antioxidant and anti-inflammatory agents, curry can reduce inflammation of the joints Studies suggest curcumin may help in slowing the progression of prostate pancreatic and colorectal cancers as well as deactivate genes that can trigger the onset and spread of breast cancer Laboratory tests indicate curcumin may make melanoma skin cancer cells more likely to self-destruct. Curcumin acts to clear the brain of protein deposits that are thought to cause Alzheimer’s Disease as well as working as a memory enhancer for healthy individuals. Curcumin has been effective in the treatment of several sexually transmitted diseases, including gonorrhea and chlamydia. New research shows ten key ingredients that are found in popular curries, such as Madras, have been associated with health benefits as well as turmeric, in conditions as diverse as lung cancer, heart disease, asthma, constipation, dementia, period pain, osteoarthritis and even loss of libido. There is definitely a lot of study to be done on the spices that make up curry powder. From all indications, curry could just be one of the “brain foods” that serve many functions as both a physical preventative but a memory enhancement, and does bear looking into as a regular part of your diet. Curcumin, which comes from the curry spice turmeric, is an isolated plant chemical that inhibits formation of beta-amyloid (a miscoded protein that accumulates in the brains of those with AD) and improves its clearance from the body. Studies investigating the potential benefits to AD have just begun. Chemically speaking, curcumin is a polyphenol, a type of chemical that may protect against certain effects of aging. Other polyphenol-rich plants include red grapes, berries, pomegranates, green tea, chocolate, and coffee. Berries are rich with a neuroprotective polyphenol called anthocyanins, which can help prevent the development of Parkinson’s disease. Grape polyphenols reduce production of beta-amyloid and protect the brain cells from its toxic effects. Lab experiments also show green tea polyphenols protect against beta-amyloid-induced nerve toxicity. People who drink green tea have a reduced risk of dementia, including AD and Parkinson’s. 60 Echinacea A native North American plant, Echinacea is something that horticultural experts are often very familiar with. Its brightly colored and attractive flowers dot the landscapes of large portions of the continent. They also show up in lots of home gardens and commercial landscaping installations, as well as some authentic horticultural restoration projects. Echinacea has been known to have some restorative qualities and medicinal uses. Today, the effectiveness of echinacea is somewhat debated, but modern research has shown the potential for echinacea as a tool for fighting viruses and keeping the immune system healthy and keeping down inflammation, a known precursor to Alzheimer’s and other forms of dementia. Echinacea is most commonly used to ward off the common cold. It can be used to treat a range of illnesses, such as fever, cold, flu or viral illnesses, as well as some kinds of infections. Researchers say that echinacea can help boost the immune system by fighting off virus microbes. It is also said to have antiinflammatory properties. Some herbalists and others call echinacea a “blood purifier” and refer to phagocytes, natural elements that the body develops to combat viral microbes. Experts claim that echinacea can help the body produce these phagocytes. Although some studies have not found that echinacea is effective in treating colds and viruses, other studies have found that taking echinacea supplements can cut down the risk of contracting a cold by nearly 50% in some individuals. That makes echinacea a popular herbal remedy, even though it’s hard to say how effective it is in any given case. Trials at universities and other research centers continue to look at how the herb might aid the body in its natural capacity to shrug off some of the common seasonal viruses that currently threaten the global community. Echinacea is often taken together with goldenseal. This herbal remedy can help fight the inflammatory and congestive elements of the common cold by soothing conditions in the inner membranes of the nose and throat. It also has some anti-inflammatory and immune boosting abilities, according to researchers. Lots of herbal remedy providers package echinacea together with goldenseal for a double punch against cold and flu viruses. Potential side effects for echinacea range from minor issues like dizziness to larger problems. Echinacea can trigger asthma attacks in individuals with respiratory conditions. Doctors often warn against using herbal supplements like 61 echinacea for those who are already on a lot of medications, as some kinds of drug interactions can apply. Before starting on a regimen of echinacea or some other herbal home remedy, it’s a good idea to have an in-depth discussion with your local family doctor about the risks and benefits of echinacea or another herbal supplement product. With the right care and attention to detail, echinacea could be worth looking at as a helper for fighting off the kinds of viruses that are creating epidemics in today’s population during each flu season. Garlic Garlic has many benefits, like lowering cholesterol to fight plaque, and helps to fight brain cancer. It also acts as an anti-inflammatory, and is full of antioxidants, which are helpful for the brain to fight against cognitive decline and memory loss, as well as for treating arthritis and asthma. According to a study published in the Journal of Cardiovascular Pharmacology, garlic protects your body and brain by lowering high blood pressure, improving circulation, reducing total cholesterol and LDL (bad) cholesterol and preventing the dangerous buildup of plaques. It helps reduce your risk for atherosclerosis and improves circulation to your brain, a key factor in preventing cognitive decline, memory loss and even Alzheimer’s disease. Garlic is high in manganese and vitamin C, which helps form the powerful antioxidant superoxide dismutase (SOD), which protects against oxidative damage, a precursor to chronic inflammation and associated diseases. A very large British study found that vitamin C significantly improved cognitive function. One ounce of garlic contains more than 23% of your Daily Value (DV) for manganese and almost 15% of your DV for vitamin C. Vitamin B6 plays a critical role in lowering levels of homocysteine, a particularly dangerous pro-inflammatory that increases your risk for cognitive decline, dementia and brain atrophy. Garlic contains almost 17% of your DV for vitamin B6. A British study found that B vitamins help reduce the risk of brain atrophy, as measured by cognitive tests, by a convincing 53%. Raw garlic is the most potent form. You can chop cloves in half and swallow with a glass of water to make sure you are getting the full power of the allicin. Or crush cloves and mix into pesto or a salad dressing. 62 Giloy Giloy is a multi-use herb that stimulates the body’s defenses against disease. It is used as a memory enhancer due to its ability to repair damaged and dying cells in the brain. It rejuvenates the nervous system, and is also used as a memoryenhancing herb, and to improve the immune system. Considered the best herb for clearing the microcirculatory system and other bodily channels, it is especially effective and unique in its ability to remove both exogenous and endogenous toxins from both external and internal sources. For this reason it is very often included in comprehensive Ayurvedic (native to Hindi alternative medicines) formulas, since such toxins interfere with all bodily functions and are a factor in almost all diseases. It clears out brain toxins that hinder mental activity. Ginger It may surprise you, but one teaspoon of ginger has similar antioxidant levels as one cup of spinach! And ground ginger can be used in both sweet and savory dishes. To satisfy a sweet tooth, Dr. Bazilian recommends this pungent spice be sprinkled onto fresh fruit slices or stirred into frozen yogurt or ice cream. In addition, Dr. Bazilian says, "Scientists are looking at the role compounds in ginger for digestive issues (nausea and others) along with its role in reducing pain." Ginkgo The gingko tree is one of the oldest trees in the world, and gingko seeds have been used in Chinese medicine for thousands of years. Gingko leaf extracts are now used to treat Alzheimer’s disease, as well as other types of dementia and memory impairment. Extracts are taken from the Gingko leaf and used to make capsules, tablets and teas. Ginkgo is an ingredient used in many memory supplements, and no list of memory ingredients would be complete without its inclusion. It helps to improve the blood flow to the brain and other organs. Medical research has proven it is effective in the treatment at the early stages of Alzheimer, or for mild memory loss. According to the University of Maryland Medical Center, scientific research supports ginkgo as a method to enhance memory and circulation. Ginkgo contains two chemicals, flavonoids and terpenoids, believed to have antioxidant characteristics, which rid the body of free radicals causing cellular damage. In 63 clinical studies, ginkgo improves the blood flow to the brain and supports cognitive functioning among individuals with dementia and Alzheimer's. Scientific studies on ginkgo's effectiveness are mixed, according to the National Center for Complementary and Alternative Medicine (NCCAM). It reports that some small studies have found ginkgo effective at improving memory, while other studies found it to have no effect on memory performance at all. Not only do they report it does not help memory, it is stated that ginkgo does not prevent decline in brain function or the onset of Alzheimer's disease. One study that does reports positive results for the use of ginkgo for memory support was published in the May 2010 issue of Pharmacopsychiatry. In this study, researchers at the Shanghai Jiaotong University School of Medicine in China tested the effects of ginkgo on cognitive decline, and found that after six months of ginkgo biloba treatment, cognitive functions of the brain were improved. Side effects of Gingko are rare, but some people have experienced allergic reactions. Also, Gingko may increase bleeding, so avoid use if you have a bleeding disorder, take anticoagulant drugs or are scheduled for surgery. *Ginseng Ginger root has many nutritional and herbal medicine varieties (including panax ginseng), and some have been proven to accelerate learning, improve reactions and aid in abstract thinking. It is popular in the United States both as a supplement, and as a tea. Ginseng is one the best known and widely prescribed herbs in Chinese medicine as a general adaptogenic and restorative tonic. Adaptogenic herbs such as ginseng are especially useful in debilitated persons suffering from exhaustion, fatigue, liver disease, stress, and wasting from chronic disease. Unfortunately, the fame of ginseng has led to misconceptions about its use and to low grade or adulterated products being sold as ginseng in the West. Panax, the generic name is derived from the Greek Panakos (a panacea), in reference to the miraculous virtue ascribed to it by the Chinese, who consider it a sovereign remedy in almost all diseases. The word Ginseng is said to mean wonder of the world, however, it is not universally applicable in every illness. It should not be taken during acute inflammatory disease or bronchitis since it can drive the disease deeper and make it worse. Moreover, in China, ginseng is rarely used on its own, but is usually combined with other herbs, such as licorice or 64 Chinese dates, which temper its powerful nature. 2 In Chinese traditions, American ginseng is considered to be more yin, helping to reduce the heat of the respiratory and digestive systems. Asian ginseng is stronger and more yang, a heat-raising tonic for the blood and circulatory systems, as understood in TCM. 1 Not all ginseng is created equal. Wild ginseng, like many other herbs is preferred over cultivated varieties. Cultivated ginseng comes in two varieties, white and red. Steaming cures the red, which gives it its color and reputedly a warmer nature than the white. Most Korean ginseng is of the red variety and is stronger or more yang in nature than that from China. American ginseng is in the same genus as Asian ginseng, but is considered a yin tonic rather than a yang tonic. As such, American ginseng is suitable for a hotter, more aggressive body constitution. It contains many of the same ginsenosides as the Asian ginsengs and has similar effects on the body. Asian ginseng is native to Korea and China. The root is dried and used to make extracts, teas and capsules. Asian ginseng protects the body from mental and physical stress. This reduction in stress can increase mental clarity and improve the memory. While research has yet proven that theory, two preliminary studies found that Asian ginseng, as an add-on to drug treatment, improved cognitive function in people with Alzheimer’s disease. Both Asian and American ginseng has been shown to boost memory in healthy people, as well. Asian ginseng is safe for most adults in recommended doses. Diabetics, however, should use caution taking Asian ginseng because it may lower the blood sugar. Suma, or Brazilian ginseng, is a relatively new addition to Western herbal medicine. Preliminary chemical analysis indicates suma contains vitamins A, E, B1 and B2; 19 amino acids including lysine, histidine, arginine and glycine; as well as small amounts of calcium, iron, potassium and sodium. Japanese researcher T. Takemoto of Tokushima Bunri University reports that suma can be beneficial in treating cases of bronchitis, high cholesterol, anemia, diabetes, fatigue and stress. He says suma can increase resistance to stress and also possesses analgesic and anti-inflammatory properties that may help alleviate pain and slow down the progress of dementia. Suma has been shown to accelerate wound healing, reduce tumor growth, and regulate blood sugar levels, blood pressure, cholesterol and hormones. Siberian ginseng is not actually a ginseng, but it has been called one because of its similar properties. It is found in Russia, Asia, northern China, Japan and 65 Korea, and Russian researchers consider it to be even more effective than Asian ginseng. Like Asian and American ginseng, Siberian ginseng has been shown to normalize reactions to physical and mental stress with great effectiveness when used for several months. A large study reviewed the results of a number of clinical trials involving 2,100 healthy men and women, ages 19 to 72. Subjects were given doses of ginseng ranging from 2 to 16 ml of fluid extract, 33 percent ethanol, from one to three times daily for up to 60 days. The subjects were found to have increased mental alertness and work output, enhanced athletic performance and improved work quality. They also exhibited an improved ability to withstand adverse conditions such as heat, noise, increases in workload and physical exertion. Siberian ginseng (eleuthero) is often recommended as a general tonic to revitalize people who are fatigued. Because it enhances immunity and helps the body deal with stress, it is frequently included in nutritional support programs for people with fibromyalgia, arthritis and other autoimmune disorders. Eleuthero restores overstressed adrenal glands, working wonders for people who are chronically stressed. The adrenal glands have a big impact on our sexual health because of the their role in producing a variety of hormone that regulate many physical responses, not just gender-oriented ones. Tonic herbs such as eleuthero help to prevent "adrenal burnout" caused by ongoing physical or mental challenges. Helping the body deal with chronic stress is the very definition of an adaptogenic herb, and ginseng may be one of the most effective herbs in this category. Eleuthero boosts concentration and focus without the letdown than comes from stimulants like caffeine. Diets, especially ones with severe calorie restrictions, can wreck havoc on a body, lowering energy levels and raising stress. This tends to elevate the levels of hormones, like cortisol, that make weight loss more difficult. When you feel more energetic and less stressed, you're more likely to stick to your new exercise and diet routine. In general, side effects with Siberian ginseng are rare and milder than those that occur with American and Korean ginseng. Not for use by pregnant women. Many commercial ginseng products are adulterated, buyer beware! Preparation Methods & Dosage: The dried root is often taken in capsules, brewed into tea, or made into tinctures. Preparation Methods & Dosage: Most Korean ginseng is cured by steaming which gives it a reddish color and a warmer nature and is stronger or more yangs in nature than that from China. American ginseng is considered to be more yin and cool in nature. 66 Ginseng is often taken for a month at a time, alternating with a two-week rest period. Ginseng powder can be taken in teas, added to other soft drinks, or even used in cooking soups. Ginseng roots are also used as extracts, and in capsule supplements. Individuals who are pregnant, or who suffer from heart conditions, high blood pressure or hypoglycimia should not take ginseng. Consult with a health professional before self-treating if you have high blood pressure. Gotu Kola An herbal extract native to Asia and Europe, gotu kola helps in the improvement of brain circulation as well as mental performance and retention. The scientific name for this herbal supplement is “centella asiatica”. It is claimed to help with focus and mental clarity. Gotu kola is an excellent vascular and blood vessel strengthener. The herb is also often used as a diuretic, antioxidant, and anti-inflammatory, and facilitates the actions of the antioxidants vitamins C and E in areas where there is damage. Gotu kola is widely used in Ayurvedic medicine to rejuvenate both mind and body, and can be used in conjunction with Bacopa/Brahmi to improve mental focus. Clinical experiments have shown that the plant does improve memory, and rejuvenate skin and body tissue, by stimulating collagen synthesis. Gotu kola may also help improve sleep and boost mood. Research has suggested that gotu kola may help improve concentration as well as memory. The main function of this herb is to improve the blood circulation in the body as well as the brain. It energies the person, as well as protects the brain cells. Its most important function is to enhance the brainpower and expand the brain’s capacity. The herb can be used as a tea or tincture, in salves, lotions and poultices. The tea will have a light, enjoyable, slightly woody taste that is improved with lemon and a bit of honey. Fresh leaves can be eaten in salads. Be cautious in taking gotu kola if you are taking prescription drugs for depression, high blood pressure, or high cholesterol. In extremely large doses it might cause nausea. Grapevine 67 The grape vine, or Vitis vinifera, is a woody climber cultivated throughout the Mediterranean. Herbalists use the seeds as antioxidants, which protect cells, tissues and organs from free radical damage. In a study published in the November 2010 issue of the Journal of Medicinal Plants Research, researchers found that grape seed extract is high in polyphenols and was effective against induced memory loss in test animals. The extract had no negative effect on normal memory, so the researchers suggest that it can also be used on a daily basis as a preventive against memory loss. Do not use this extract if you are pregnant or nursing. Green Tea Green tea is produced from the fresh leaves of the Camellia sinensis plant. Extracts can be taken in the form of capsules, or drunken as a beverage - hot or cold. Green tea is full of antioxidants and is shown to improve mental alertness and memory. Green tea is safe when used in moderation. Concentrated green tea extracts should be taken with food. There have been rare cases of liver problems reported with the use of concentrated green tea extracts. Green tea contains caffeine, so if you are sensitive to caffeine, green tea should be limited or avoided. Flax/Flaxseed A happy brain needs B vitamins, manganese, magnesium and dietary fiber. Tiny flaxseeds are a great addition to the memory healing diet. Filled with B vitamins, minerals and fiber, they pack a supersized punch when it comes to protecting your brain from cognitive decline. B vitamins, particularly folate, are essential to the synthesis and regulation of neurotransmitters and neuropeptides, the chemical messengers in your brain that allow neurons (brain cells) to communicate with each other. The folate in flax reduces chronic inflammation and helps lower levels of homocysteine, a dangerous proinflammatory amino acid. According to a study published by the American Journal of Psychiatry, homocysteine disrupts the function of neurotransmitters and can lead to cognitive decline. The Australian study of more than 200 women, a diet high in folate and vitamin B6, such as that found in flaxseeds, helped improve mental function and short-term memory. 68 A study published in the American Journal of Clinical Nutrition found that elderly people who ate a diet high in dietary fiber scored higher in cognitive tests than those who did not. Just 2 tablespoons of flaxseeds provide you with more than 21% of your DV for dietary fiber. You can find whole or ground flaxseeds and flaxseed oil in your local health food store. Make sure you buy flaxseed oil that has been kept in a refrigerator and is marked “high in lignans.” At home, store flaxseeds in an airtight container in a dark place. Ground flaxseed meal and flaxseed oil should be refrigerated and tightly sealed to avoid spoiling. Do not heat flaxseed oil, as that destroys its nutritional benefits. Drizzle it on salads and cooked foods, or take it by the spoonful. Horsebalm Shampoo Some compounds in horsebalm apparently can cross the blood-brain barrier, which means it might have some positive effects on memory even if you use it as a shampoo or skin lotion. You won't be able to buy shampoo that contains horsebalm, but it's easy to make your own from this garden flower. Simply add several droppers full of horsebalm tincture to your favorite herbal shampoo. * Jiaogulan Jiaogulan (Gynostemma pentaphyllum), is a member of the gourd family that grows in southern India, China, Korea, and Japan. It is relatively new to the list of adaptogens. Preliminary studies suggest that jiaogulan may have even more powerful regulatory effects on a number of body systems than does Asian ginseng. Jiaogulan has demonstrated antibacterial and antiinflammatory activity, and have a beneficial effect on blood pressure regulation. Inflammation has been found to be one of the symptoms of dementia, so anti-inflammatories are necessary to fight the onslaught of memory problems. Jiaogulan has also been shown to bolster the immune system, improve fat metabolism, moderate cholesterol levels, and enhance strength and physical endurance. Lemon Balm 69 Lemon balm is an herb that is native to southern Europe, although it is grown all over the world. The scientific name is “Melissa officinalis”. It has many uses, from a garnish for iced tea to perfume oil, according to a report from the North Carolina Cooperative Extension Service. A lesser-known benefit of lemon balm is its ability to positively affect brain function. A report in the American Journal of Alzheimer's Disease and Other Dementias (2006 edition) states that lemon balm improves brain function, including the areas of memory, judgment and problem solving, and within 16 weeks of treatment relieves anxiety. * Licorice Root Licorice root (Glycyrrhiza glabra and G. uralensis), another popular herb in China, is said to tone the spleen and strengthen chi. Licorice is perhaps the only herb claimed to benefit all 12 meridians in Chinese medicine. Rich in both saponin chemicals and flavonoids, it is anti-inflammatory because the saponins have a structure similar to that of corticosteroids. Licorice root also promotes or enhances the functions of the immune system, and has a stimulating effect on the adrenal cortex. Additionally, licorice can slowdown the breakdown of adrenal hormone by the liver, thereby increasing corticosteroid levels in circulation while inhibiting cortisol's ability to promote thymus shrinkage. One note of caution: Because of its aldosterone-like effect, licorice root may cause sodium retention and can contribute to high blood pressure in some people. Malkangani This Indian herb, also known as the intellect tree, is used in mental treatment as a sedative and antidepressant. Although it was used in India for centuries as a brain tonic for people suffering from memory loss, only within the past few years has started to become known outside of the traditional medicinal practice of India. The oil of the malkangani is used to increase memory and expedite learning. It brings about a feeling of well being, and has been reported to have aphrodisiac effects. It has properties that protective the neurons and helps improve memory loss. In its raw state the oil has a shelf life of 2 years when kept in a cool and dark place - like a refrigerator. When put into softgel tablets the shelf life is expected to be much longer - perhaps up to 4 years if kept in a dark and refrigerated state. Matcha 70 Since ancient times, in the Japanese culture, their tea ceremony is focused on the preparation, serving and drinking of matcha. In modern times, matcha has been used to flavor and dye foods such as mochi and soba noodles, green tea ice cream, and a variety of wagashi (Japanese confectionery). Matcha is a finely ground powder of the highest quality for green tea, and not the same as tea powder or green tea powder. Its unique effects on the brain are a perfect fit for Buddhist monks when they are preparing for a 12-hour straight meditation session. It allows them to become more focused and calmer, but at the same time stimulated. Medhya Dravya This herb, or Licorice plant (Glycerrhiza glabra) is a new addition to Ayurvedic medicine for memory enhancement. It is said to have a number of benefits along with memory sharpness - such as the prevention of cough and cold, improving eyesights and cure against gastric ulcers. It is said to be the best herb for improving your memory. Muleti Muleti is the perfect herb to rejuvenate the brain. It is mainly used as a stress relieving medicinal herb due to its calming effect. This helps in the overall brain development keeping it calm and cool. It also improves the blood circulation in the nervous system. Muleti is an important ingredient in any brain enhancing tonics given to students and children for memory improvement. *Mushrooms * Reishi (Ganoderma lucidum), shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms may not be adaptogens in the classic sense, but each has adaptogenic, antitumor and immune-potentiating properties. Reishi and shiitake traditionally have been used as tonics, while reishi has been called the elixir of immortality. The Japanese have used Lion’s Main Mushrooms for centuries to enhance mental performance. This herb has been shown to contain erinacines, which may assist nerve and brain cell growth. The scientific name is “hericium erinaceus”. Lion's Mane Mushroom is one of the most interesting medicinal mushrooms. The tea is used primarily as a "tonic", and research has found all use of it has been as involved the use of hot water extracts. This is because the active compounds 71 are found inside the cell walls, and, like all medicinal mushrooms, the cell walls of Lion's Mane mushrooms and mycelium are composed of an indigestible fiber called "chitin". Hot water extraction is the only research-validated process for breaking the active compounds out into a bioavailable form. Modern scientific research now tells us it was the beta glucans in the mushroom tea that were in fact offering immune support, among other health benefits. Studies also indicates that the hot water/alcohol extract of Lion's Mane may stimulate the synthesis of Nerve Growth Factor (NGF) and may promote and accelerate the process of myelination. There has not been any research done on the unextracted mycelium powder of Lion's Mane mushroom nor has there been any research done on the tinctures of Lion's Mane mushrooms or Lion's Mane mycelium (liquids preserved in alcohol). The Mushroom Science Lion's Mane supplement is the only guaranteed potency hot water extract on the market, and the only Lion's Mane supplement that lists guaranteed levels of active compounds on the label. Oregano "I call oregano a 'mini salad,' says nutritionist Dr. Bazilian, "one teaspoon has as much antioxidant power as three cups of chopped broccoli (but don't ditch the broccoli – have both!)." Oregano has one of the highest antioxidant levels in the dried herbs category and it goes works effortlessly as a flavoring in many of our favorite dishes. Expert dieticians recommend adding oregano to commercial or homemade pasta or pizza sauce, or sprinkling it onto a grilled cheese sandwich. According to a Swiss study by researchers at the University of Bonn, oregano is the "ultimate inflammation fighter" because of betacaryophyllin (E-BCP), its active ingredient. It also is an outstanding source of luteolin, where the extract may be effective in enhancing mental well-being. Other studies have found that oregano also contains phytochemicals thymol and carvacrol, powerful antifungal agents. The oil of oregano has a strong antibacterial action against a range of germs, including those responsible for E.coli, salmonella and the common cold. Parsley 72 Parsley is not just a garnish. The luteolin found in the parsley has been found to slow cognitive decline in older mice. Luteolin can be found in both dried and fresh varieties of most herbs. Pepper Scientific studies researching the main ingredient in black pepper (piperine) found the spice not only improved memory performance in mice that carry the Alzheimer’s gene, it also had antioxidants and delayed degeneration of brain cells in the hippocampus - the memory center of their brain. Spices extracted from red peppers include crushed red pepper, cayenne, and paprika. A real “hot-n-spicy” spice, cayenne pepper has been found to increase blood flow throughout the body to reduce the risk for heart disease. Increasing the blood flow is good for the brain. This spice is also used for elimination of gas in the intestines, and could reduce the risk of sore throats and flu, as well as help speed up the metabolism to lose weight. Red peppers, in their various different forms, have shown promise for enhancing metabolism, increasing the ability to satisfy and feel full, and possibly increase fat burning. Crushed red peppers, cayenne and paprika can be used to spice up hummus, guacamole, cottage cheese and even mashed potatoes. They can give marinades or dressings a little kick with a sprinkle of cayenne or paprika onto fish for a tasty change. Peppermint Peppermint leaves has been used by traditional medical practitioners for centuries. One of the benefits of peppermint is said to be increased brain function, especially since it is an excellent source of luteolin. A study conducted in the 1990s at the University of Cincinnati found that a whiff of peppermint or muguet, a scent similar to lily of the valley, helped their test subjects concentrate and do better on tasks that required sustained concentration. Joel Warm, a professor of psychology, who along with his friend, the late William Dember, said there is more than a bit of truth in the peppermint 73 theory. “Not only do you get an improvement [in focus] with peppermint, you get a change in response that affects alertness in target detection,” he said. At Wheeling Jesuit University in West Virginia, professor of psychology Bryan Raudenbush found that athletes who had a sniff of peppermint performed better than those who didn't. Rhodiola If you feel burned out, or suffer from body weakness, depressed moods, poor concentration, insomnia, or lethargy—here’s something to chew on. A new study out of Sweden suggests rhodiola rosea (also known as Arctic root), can be very effective for combating stress-related fatigue, commonly known as burnout. In the controlled clinical study, 60 subjects with burn out received either four tablets (576 mg) daily of the rhodiola root extract or four placebo tablets. After 28 days, volunteers were evaluated for fatigue, quality of life, depression and attention. Their cortisol levels were tested through their saliva on the first and 28th days of treatment. Cortisol, a stress hormone, increases in response to stress. Although subjects in both the rhodiola and placebo groups showed improvement in several areas, including quality of life, the rhodiola group had a much greater reduction of fatigue; was better able to focus attention; and made fewer errors. Perhaps most telling, saliva cortisol was substantially lower in the rhodiola group than in the placebo group at the end of the trial. The authors all agreed that rhodiola “exerts an anti-fatigue effect that increases mental performance, particularly the ability to concentrate.” Rhodiola, a plant found in cold, sub arctic regions, has been studied for its ability to help the body and mind adapt to stress. Research on rhodiola and similar herbs, known as “adaptogens,” began in the former Soviet Union; more recently, Scandinavian researchers have focused on the herb. Head of research and development at the Swedish Herbal Institute, Alexander Panossian, Ph.D., has published numerous articles on adaptogens. He believes both that stress overload is a risk factor for dementia and that “adaptogens might be very beneficial in preventing dementia.” Although research has yet to prove that stress definitively causes dementia, two preliminary studies found that Asian ginseng, as an add-on to drug treatment, improved cognitive function in people with AD. Both Asian and American ginsengs have shown to boost memory in healthy people, as well. 74 Another promising adaptogen is rhodiola. Recent research conducted by Panossian and others show rhodiola improves symptoms of anxiety, depression and stress, and reduces mental fatigue. Rhodiola hasn’t yet been studied in people with dementia. Nevertheless, Richard P. Brown, M.D., and Patricia Gerbarg, M.D., authors of The Rhodiola Revolution, found that rhodiola can enhance memory and cognitive function in their patients, including those with age-related memory decline and mild dementia. Rosemary On the scale of magical awesomeness, rosemary ranks pretty highly. It’s sumptuous, and may actually make you smarter. A study at the UK’s University of Northumbria exposed participants to the scent of rosemary oil. Each subject was given cognitive tests before and after smelling the oil. Blood work was then done to determine how much eucalyptol (rosemary’s primary chemical component) was present in each person’s blood stream, and what they found was that higher levels of the chemical in the blood turned out to accompany higher test scores across the board. As Dr. Alan Hirsch, of Chicago’s Smell and Taste Treatment and Research Foundation, said, “This opens up the doorway for us to explore other odors and how they affect people.” Diffuse rosemary essential oil in your workspace to maintain your focus at work, and try a cup of rosemary tea instead of coffee to stimulate concentration and focus. For morning sluggishness try a brisk rosemary rubdown in the shower. Add 2 to 3 drops to a washcloth along with shower gel and massage over the body. Rosemary is native to the Mediterranean and has long been used for medicinal purposes. Rosemary grows well in most climates and today it can be found in many herbal gardens, which isn’t surprising since it’s a super antioxidant. Research has found that rosemary protects the brain and prevents memory loss by preventing the breakdown of a chemical that induces the brain cells responsible for memory. Rosemary or Rosmarinus officinalis is a common spice found in many home cupboards. While it can add zest to food dishes, it also has medicinal benefits. Rosemary has been used for centuries to give support to the nervous system, circulatory system and improve memory, according to the University of Maryland Medical Center. One method of using rosemary to improve concentration and memory function is through aromatherapy. Researchers at the University of Northumbria in the U.K. tested the impact of rosemary and lavender essential oil on cognitive function. The results, published in the January 2003 issue of the 75 "International Journal of Neuroscience," showed that rosemary oil was superior in enhancing memory function. The UMMC reports that rosemary can also relieve anxiety in some people, but there are others in which rosemary aromatherapy actually increased anxiety. Saffron A study in 2007 found saffron to work as well as Prozac and other antidepressant drugs in treating mild-to-moderate cases of depression. Depression can cause memory problems. Add ½ teaspoon of saffron to 2 cups of rice. The antioxidant properties are on a par with strawberries, cherries and raspberries. Sage Sage oil helps to boost production of chemicals in the brain that are known to have been depleted by Alzheimer. It has antioxidants and anti-inflammatory properties, which may be helpful with memory improvement. We all have heard, and probably cringed at, the jingle “Cha-cha-cha-chia,” the theme song for those terracotta figurines that sprout green “hair.” They come in a wide selection of styles, and are just a lot of fun to watch as the seeds are wetted and the “hair” starts to grow. Who would have thought that the “hair” of the chia pet is actually brain food? Moistened seeds of chia (Salvia hispanica), commonly known as the herb “Sage,” are applied to the grooved terra cotta figurine body and grow quite rapidly. Salvia hispanica chia seeds have been used as medicinal food and healing for centuries. Their seeds are rich in Omega-3 fatty acids, also known to enhance memory. Chia is aggressively being marketed under the trademark Salba, and touted as an "Ancient Aztec Superfood" selling for as much as $6o a pound, but the average person can enjoy the many health benefits of the organically grown seed at a much more economical price from most local health food stores – or buy a chia pet and grow it yourself! Chia, or sage, is a remarkable herb. Many properties include enhancing wisdom, healing, and are often used in spells involving wishes or the healing of others. Carrying sage is said to provide protection, both physically and metaphysically, as well as maintain the three kinds of health (Mental, Physical, and Emotional). One old wife’s tale says to tie three sprigs of sage together with a white ribbon and placed under a bed is said to prevent nightmares and fend off negative energies. Herbalists and holistic practitioners have believed for centuries that sage has the 76 ability to invigorate the nerves. Recent scientific evidence actually supports this theory. It is a natural herb used to support brain and memory health, and prevent common forgetfulness associated with normal aging. It also is used to naturally support mental health, assist the body’s natural ability to store and memorize information, and supports the nervous system by maintaining natural blood flow. Some research is now being done to see the effect of sage in Alzheimer’s disease, as it is used to improve memory and nervous conditions. A 2003 study, published in Pharmacology, Biochemestry and Behavior involved 44 healthy adults, 22 taking a sage oil capsule and the other 22 getting a placebos. A word recall test was administered, and those who took the sage were able to recall more words, suggesting the herb’s reputation as a memory system booster was not an old wife’s tale. “This proves how valuable the work by the old herbalists is, and that they shouldn’t just be ignored because they were writing centuries ago,” says Medicinal Plant Research Center researcher, Nicola Tidesley. “The herb has antioxidant and anti-inflammatory properties that could slow the disease’s progress and alleviate existing symptoms.” That would also mean the synonym for sage – wisdom, may not be so far off base! Grown primarily in Europe, sage (Salvia officinalis) is a universal herb. The peppery flavor has been popular for centuries as a seasoning, and many different cultures have found the herb useful for medicinal as well as other purposes. The Greeks used sage as a cure for stomach ailments; Egyptians used it to fight off the plague; Chinese made teas to cure sore throats and laryngitis; and the Romans and Native Americans used the herb in religious ceremonies, believing it provide longevity and banished negative energies. Many of these cultures also valued sage as a tool to enhance wisdom and increase memory. Holistic practitioners and herbalists believed for centuries that sage has the ability to invigorate the nerves, and there is scientific evidence to support this theory. A study conducted in 2003, and published in Pharmacology, Biochemestry and Behavior, involved 44 healthy adults - half taking a sage oil capsule and the other a placebo. The subjects were then administered a word recall test. Those taking the sage were able to recall more words, suggesting the herb’s reputation as a memory system booster was not an old wife’s tale. From this study scientist were eager to go further and see if the herb would work on patients who are battling Alzheimer’s disease (AD) and other forms of dementia. “This proves how valuable the work by the old herbalists is, and that 77 they shouldn’t just be ignored because they were writing centuries ago,” says Medicinal Plant Research Center researcher, Nicola Tidesley. “The herb (sage) has antioxidant and anti-inflammatory properties that could slow the disease’s progress and alleviate existing symptoms.” The exact cause of AD is unknown, but some physicians believe an accumulation of aluminum in the brain, or a defect in the production of a brain chemical called acetylcholine (involved with short-term memory) is the cause. Sage is believed to bind to specific receptors in the brain and imitate the action of acetylcholine. Another study, published in the Journal of Clinical Pharmacy and Therapeutics (2003;28:53–9), suggests sage may lead to symptomatic improvement of AD, and people who take daily doses of may experience memory improvement, and decreased agitation. In this study, 30 adults with mild to moderate AD, between the ages of 65 and 85, were randomly assigned to receive 60 drops per day of sage extract or placebo for four months. Two rating scales - the Alzheimer’s Disease Assessment Scale and Clinical Dementia Rating Scale, were used to measure the degree of impairment in cognitive functions such as memory, orientation, judgment, problem solving, speech, and personal care. Higher scores suggest more severe impairment. Participants were assessed every two weeks for the duration of the study. Those taking the sage extract, as opposed to those taking the placebo, showed significant improvements in cognitive functions in all areas after 16 weeks of treatment. The Alzheimer’s Disease Assessment Scale findings increased in the placebo group by 22% (increased signs of AD deterioration), and decreased by 26% in the sage group. Agitation levels and frequency for the placebo group was higher than those of the sage group as well, indicating sage may also have a positive effect on moods. With this evidence in hand, scientists are looking at sage, along with lemon extract and ginkgo-biloba as possible “brain food” or supplements to aid in the treatment of diseases that attack the memory system and age-related cognitive skills. * Schisandra Schisandra it touted to improve memory as well as bring about a sense of wellbeing and mental awareness. A native to East Asia, and its dried fruit is used medicinally. In traditional Chinese medicine, schisandra is used as a remedy for many ailments - to resist infections, increase skin health, and combat insomnia, coughing, and thirst 78 Schisandra is commonly used as a tonic to promote liver health. And has been as an adaptogenic tonic to counter the effects of stress and fatigue. Scientific studies show it has an effect on persons with insomnia and neurasthenia by normalizing their breathing, and improves mental coordination as well as physical endurance. Research also suggests the herb may actually influence electrical discharges in the brain. Sesame Seeds Open a jar of raw sesame butter (tahini) for a healthy brain treat. Sesame seeds are full of zinc, a mineral important in learning, memory and brain development. Zinc is also part of the brain's defense system, because it promotes immune health and drives enzymes that keep a healthy balance of trace metals in the brain. For a tasty source of zinc, add hummus with sesame seeds or tahini. *Shankhpushpi This is the most common and most used Ayurvedic Herb. Shankhpushpi is said to be a natural memory enhancer, and helps sharpen the brain. It has been used from ancient times in India as a memory tonic as well as a medicinal herb to relieve mental stress as well as controlling blood pressure. People use this herb in India for children during their exams, and believe it aids in the brain development. It is widely used in treating nervous and mental disorders. It acts as a brain tonic, treats insomnia, boosts memory and reduces mental fatigue, helps in maintaining good cholesterol levels and aids in the prevention of aging and mental decline. Turmeric Want to spice up your life in more ways than one? Add curry to your meals! It is statistically a fact that those who live in South Asian countries, where the use of the curry to season foods is common, have a lower incidence rate for Alzheimer’s Disease. Is it a coincidence? Curry powder is a combination of spices, and it varies by country, but the one ingredient that is common to all curried mixtures is "turmeric." Curcumin is the 79 substance that gives the spice turmeric its yellow color and is also responsible, at least in part, for some of the health benefits of curried dishes. Scientists have long known that curcumin is good for improving memory. Now they know why. The spice is a powerful antioxidant that has been shown to protect nerve cells. One theory is that the spice acts as a “scavenger,” attacking free radicals that harm the nerve cells involved in forming memories and mental functions. This information can be very valuable in the search for a cure to mental diseases like Alzheimer’s and Parkinson’s. “Since it has both neuro-protective and memory-enhancing properties, it may be unique in treating clinical disorders associated with the loss of nerve cells and cognitive abilities,” say researchers at the Salk Cellular Neurobiology Laboratory, one of the world's leading research centers. In the search for ways to treat individuals who have suffered traumatic brain injury (TBI) and stroke, researchers at the Salk Institute are studying a curcumin-derivative compound, known as CNB-001. Salk researchers have found that CNB-001 improves dramatically both “behavioral and molecular deficits of ischemic stroke and TBI in animals.” The compound has shown to be extremely neuro-protective in all of the studies, while enhancing memory in normal animals. It has shown significant results in protecting nerve cells that occur in brain injuries, as well as age-related neurodegenerative diseases such as dementia. Other health benefits that have been associated with ingredients in curry include: Due to its powerful antioxidant and anti-inflammatory agents, curry can reduce inflammation of the joints Studies suggest curcumin may help in slowing the progression of prostate pancreatic and colorectal cancers as well as deactivate genes that can trigger the onset and spread of breast cancer Laboratory tests indicate curcumin may make melanoma skin cancer cells more likely to self-destruct. Curcumin acts to clear the brain of protein deposits that are thought to cause Alzheimer’s Disease as well as working as a memory enhancer for healthy individuals. Curcumin has been effective in the treatment of several sexually transmitted diseases, including gonorrhea and chlamydia. New research shows ten key ingredients that are found in popular curries, such as Madras, have been associated with health benefits as well as turmeric, in 80 conditions as diverse as lung cancer, heart disease, asthma, constipation, dementia, period pain, osteoarthritis and even loss of libido. There is definitely a lot of study to be done on the spices that make up curry powder. From all indications, curry could just be one of the “brain foods” that serve many functions as both a physical preventative but a memory enhancement, and does bear looking into as a regular part of your diet. Thyme A teaspoon of thyme has about the same amount of antioxidants as a carrot, or ½ a cup of chopped tomatoes. And the flavonoids and luteolin in this spice give it antioxidant properties as well. There are some studies that suggest these antioxidants may have age-related benefits like helping to maintain cognitive function and promote heart health. Vacha Also known as Sweet flag, Vacha is another herb used to improve brain functioning and enhance memory. The roots of vacha herb contain some essential oils and terpenoids, which help in giving the sedative action that, strengthen the nervous system. It gives instant results in terms of improving the memory as is prescribed for persons suffering from amnesia and other memory disorders. Vinpocetine Vinpocetine is an extract of the periwinkle plant. It is an herbal aid for improving memory and concentration, and acts to help increase blood flow in the part of the brain used for memory storage. You should know by now that when your brain does not get enough oxygen your memory will begin to suffer. It is starving for oxygen to provide the essential nutrients it needs to keep it going. As you age, your circulation begins to drag and slow down. You become more sluggish. When there isn’t enough blood flow to carry oxygen to your brain you can suffer memory loss and even serious mental decline. The good news is, scientists have discovered an extract of the periwinkle plant that they believe can boost blood flow to the brain and keep it from starving to death. Studies have found that vinpocetine helps people to recall new information quickly and help them become more focused. Even people who are suffering serious mental decline will notice a difference! 81 In one study, elderly patients with serious memory impairment were given either a placebo or vinpocetine. Of those who took vinpocetine, after just 3 months 100% of the subjects scored better in memory tests than those who took the placebo. That’s right, 100% of the people in the study who took vinpocetine saw an improvement! If that doesn’t convince you that vinpocetine can make a big difference in your memory and thinking than what will? After taking vinpocetine, you will notice less frustration over lost items, forgotten names, or fewer senior moments! Food for Thought 1. Have you thought of the herbs and spices you add to your food as being good for your brain? 2. To enhance your brain health, do you see where adding some spice to your life through food is a good investment in your overall health? 3. What type of antioxidant do you think you could incorporate into your diet that will enhance your memory and brainpower? 82 Chapter 7 Supplement Your Diet For Brain Health Most people, if they eat a healthy diet, exercise, reduce stress and get better rest will not need to take supplemental vitamins or herbs. Lifestyles that take in all of these should provide all the nutrition you will need to keep your brain healthy. It will never hurt to add more brain food to your healthy diet, like adding coldwater fish more often to your diet. Include more foods that contain vitamin B’s and antioxidants. Supplements and vitamin tables are just that - supplements, which means they are “in addition” to your main diet. Your goal should be to achieve a healthy lifestyle. For those of you who have already done the job of optimizing your diet, making sure you get enough sleep and lowering your stress it is possible that supplements can help you get that edge, but they are not necessary. Make certain that before you try and of these products you do the research that is necessary to make sure they don’t have allergic reactions, side effect or interfere with medication or other supplements. Supplements are taken for a number of reasons, to become more healthy while losing weight, gaining weight, enhancing the function of some part of your body (including your memory), etc. There are various things to consider, however, before taking a dietary supplement. What are dietary supplements? Congress created the Dietary Supplement Health and Education 83 Act in 1994. This piece of legislation defined what constituted a supplement. This would include: That the supplements must contain at least one or more dietary ingredients such as vitamins, minerals, herbs or other botanicals, amino acids, or their counterparts That their purpose is to supplement the diet Are to be in pill, capsule, tablet or liquid form intended to be taken by mouth Labeled on the front panel that they are dietary supplements Companies that manufacture dietary supplements must first obtain approval from the Food and Drug Administration (FDA) by giving evidence that the specific supplement is both effective and safe. Unlike prescriptions and over-the-counter medications (OTC), however, supplements and herbal products are not tested for their validity or safety. The only way a product can be removed or restricted from the shelves is if the FDA can provide evidence that the product is unsafe. According to the FDA, "Many supplements contain active ingredients that have strong biological effects in the body. This could make them unsafe in some situations and hurt or complicate your health. For example, the following actions could lead to harmful -- even life-threatening -- consequences:" Taking supplements with medications - either prescription or OTC Using more than one supplement at a time Using supplements as a substitute for prescription medication Overloading your system with some supplements that could store themselves in the body instead of being released, and build up a toxicity Taking supplements before, during and after surgery that are contradicted by your physician It is extremely important that you always tell your doctor or health care providers what supplements you are taking. If you are considering taking supplements, do your homework first. Look to reliable resources for your scientific information - not the website of the manufacturer or reseller. There is a lot of valuable information out there from reliable studies and sources that you can get truthful information. Three such reliable sites to check out are: Consumer Lab (Consumerlab.com) - Each supplement must pass product reviews or voluntary certification to be posted on this site. A Consumer Lab Seal of Approval is given to the manufacturer (they have to purchase the license) if it passes the inspection. 84 US Pharmacopeia (www.usp.org) is an independent testing agency. Manufacturers may display the USP Verified Dietary Supplement seal on their product label if product passes ingredient and product integrity, purity and potency testing. NSF Dietary Supplement Certification (www.nsf.org) - The products that are allowed to display the NSF mark have undergone third party testing for identity, quality, purity, and consistency. In addition, there are free publications, clearinghouses and information on the websites of the National Center for Complementary and Alternative Medicine (SCAM) and the National Institutes of Health (NIGH) Office of Dietary Supplements (ODS). If you decide that your diet alone is sufficient, and opt out of taking any supplements, speak with a dietitian. They can show you the proper foods to eat to meet your specific goals. As you can see from above, many fruits and vegetables are considered super foods, and can play a significant role in meeting and exceeding your requirements for a good balance of vitamins, mineral and antioxidants. In addition, dieticians can show you some tricks, tips and food combinations that will maximize the way your body metabolizes what you eat. One example, foods with vitamin C foods can help improve the way the body absorbs iron. A study out of the France, from the University of Paris XIII, has found that an increased intake of vitamins and minerals could, over time, boost your memory power. There is nothing outrageous about this idea, since a good balance of the proper nutrients in your diet benefit memory and cognitive skills. According to their study, adults who took vitamin and mineral supplements for over 10 years did better on one type of memory test than those who didn't take the supplements. "The question is, does the cognitive performance depend on the diet, or does the diet depend on the cognitive performance?" asks Geraldine McNeill, a nutritionist at the University of Aberdeen in the UK. “It's possible that people who have better thinking and memory skills might pay closer attention to what they're eating,” she explained. In 1994, when the age groups of the participants were from 45 to 60 years old, researchers split 4,500 French men and women into two random groups. Half of them were asked to take a daily supplement that included vitamins E and C, 85 selenium, zinc, and beta-carotene. They took the supplements for eight years. The others took a nutrient-free placebo pill every day. None of them knew if they were taking the vitamins or the placebo. At the conclusion of this portion of the study, researchers stopped giving participants their assigned pills, and told them they could choose whether or not to take vitamin supplements. An additional six years later, researchers brought them back for a round of memory tests that included word and number problems, measuring different types of memory and "mental flexibility." Although each groups performed very much the same on most tests, the nutrientboosted participants beat them out on one test for long-term memory, in which participants had to recall words in different categories. McNeill stated that most people could simply make changes in their diet to get the same amount of vitamin and nutrient dosages used in the study, like substituting orange juice for vitamin C. A nutrition researcher at Tufts University in Boston, Barbara Shukitt-Hale, states that it's important for people to understand that boosting your brainpower requires more than just taking a vitamin pill every day. "Vitamins and minerals are important for memory, but they're not the only thing that's important," she told Reuters Health. "The most important thing is eating a healthy diet, being active, and keeping your brain sharp." If you are not comfortable that your diet does not provide the needed coverage, and you have consulted your health care provider, taking memory-enhancing supplements can give you an edge on improving your short-term and long-term memory. They can help to increase mental performance, productivity, focus, energy and self-confidence. Some people even say that their use of memory enhancing supplements have greatly reduced their daily stress levels, and that they now feel great in spite of difficulties and challenges that come their way. There are no right or wrong supplements to select. You can always look at the strengths and weaknesses of each and let that be your guide. Or, you can try different ones and see which work best for you. Remember for the best results, long-term use is ideal. There are micronutrients that your body needs and can not product itself, so has to rely on the food you eat or supplements of some kind. Supplements have become a common method of making sure that you receive the right amount of daily vitamins. There is a possibility, however, that your vitamins are doing more harm than good for your health. Organic vitamins are hopefully the answer to that problem. Most vitamins being commercially sold today include ingredients such as 86 chemicals and synthetics ingredients. It is needless to say; these ingredients can end up harming your health more than helping you. Organic vitamins are produced under strict conditions, unlike ordinary vitamins, to ensure that the products do not contain insecticides, pesticides and other synthetic ingredients. Keep in mind, however, that although quality organic vitamins are free from toxic chemicals, they could still contain some animal-based ingredients, especially in the gelatin of the capsule. I you are a vegan or vegetarian; you may have to exercise caution. When buying organic vitamins, first make sure that the product has a USDA organic label to prove the vitamin is a certified organic product. Certified organic products contain 95% organic ingredients, making them healthy and environmentally friendly as well. If you want an all-organic vitamin product, then look for vitamins with a 100% certified organic label. To make it easier, you can also choose multivitamins. Multivitamins contain most essential vitamins that you will need. This eliminates the need to look for different types of vitamins. For those who don’t enjoy swallowing capsules, organic vitamins also come in liquid form. If you are having a hard time trying to get your kids to take solid vitamins, liquid vitamins may also be suitable. Just like ordinary vitamins, organic vitamins are only meant to be consumed as supplements, so should never be your primary source of nutrients. Also, Just because you are regularly taking complete vitamins it does not mean you can indulge yourself with a diet of junk food. When choosing organic vitamins, it's also important to consider your individual health needs. For example: vegetarians will need more vitamins that come from animal sources, such as vitamin A and vitamin D. Pregnant women will need more vitamins B and E. Below are supplements that help increase your brain activity: Alpha Lipoic Acid Alpha lipoic acid (ALA) is an amazing antioxidant that easily crosses the wall between the brain tissues and circulating blood (the blood-brain barrier). ALA’s job is to convert glucose to energy, and can work in both water and fatty tissues. The process of converting food to energy creates free radicals, which damage the body's cells and weakens the immune system, organs and tissues. ALA destroys the free radicals and re-energizes the depleted antioxidants to make them effective again. Supplements are the best way to increase ALA in your system. 87 ALA also works as an antioxidant agent in neurodegenerative diseases because it can interrupt damage from free radicals at several points. It has been shown to elevate antioxidants in various brain regions, improves memory, and supports healthy blood glucose levels. Acetyl L-Carnitine/ALCAR Known for its ability to cross the blood-brain barrier (the separation of circulating blood and the brain fluid in the central nervous system), acetyl L-Carnitine (also known as ALCAR) is an amino acid that helps with the production of energy that is necessary for optimal brain function. It acts as a powerful antioxidant in the prevention of the brain cells' deterioration. ALCAR naturally occurs in plants and animals. Bodybuilders like acetyl l-carnitine can help muscles grow stronger during exercise. Brahmi/Bacopin Brahmi has been used in traditional Indian medicine (Ayurveda), and is used for the treatment of Alzheimer’s disease, allergic conditions, to fight stress and to treat irritable bowel syndrome. People also take brahmi to treat backache, hoarseness, mental illness, epilepsy, joint pain, and sexual performance problems in both men and women. Sometimes it is used as a “water pill.” Be careful not to confuse brahmi (Bacopa monnieri) with gotu kola and other natural medicines that are also sometimes called brahmi. This herb may increase certain brain chemicals involved in memory, learning and thinking. Studies have suggested that it also protects the brain from harmful chemicals involved in Alzheimer’s disease. Clinical trials have found that brahmi can relieve anxiety and memory retention, and recently the trials have extended to its effect on mild to moderate mental deficiencies. Memory studies, involving both rats and humans, on this plant have shown a significant increase in both memory retention and speed of learning, as well as overall improvement in general cognitive skills. 88 The herb also works within the body to counteract the effects of stress, not only on brain processes related to stress but other body functions as well. It may also have a protective effect in helping reduce the effects on the stomach from stress, helping to eliminate the risk of ulcers. Bacopin research has also highlighted the antioxidant properties of this plant. It seems it acts as a scavenger for free radicals in the body, and protects cells from free radical damage. Scientists believe that damage to the nerves from free radicals is a contributing factor in many of the age related cognitive issues see in the elderly, particularly in dementia, Alzheimer's and age related memory loss. Supplements of bacopin could have a protective effect that helps to prevent or delay these types of age related issues. Carnosine/L-Carnosine Carnosine, or L-Carnosine, is a general-purpose supplement that helps protect cells and tissues against negative effects of aging. As a broad-spectrum antioxidant its antioxidant effects appear to protect the brain from strokes, and helps to defend against age-related decline of mental and immune functions. Cholecalciferol Cholecalciferol is a more technical name for vitamin D3, and is the most active form of vitamin D in human biology. Vitamin D3 helps to regulate your anti-stress hormone, and helps in the circulation of your blood as a macrophage, part of the first line of defense against foreign bacteria. Higher levels of vitamin D3 can help alleviate your stress-induced symptoms depression, agitation and anxiety, and strengthen your immunity against infections and cancers. Its main function is to help in the absorption of other minerals like phosphorus and calcium. It also contains a variety of metabolic pathways called co-enzymes that regulate blood pressure, the release of hormones, and conduction of nerve impulses. In addition, cholecalciferol has antioxidant functions against microbial pathogens, and is a subcomponent of certain structural proteins and steroids. Usually OTC vitamin D3 comes in a complex with calcium supplements, multivitamins or fish oil capsules, or in isolated pills. Taking vitamin D3 supplements during cancer treatments can lead to improved efficacy and better results. CoEnzyme Q10 or CoQ10 89 A protein, known as CoEnzyme Q10, or CoQ10, fuels your heart. You may not have heard of it before, but it's important that you understand why this nutrient is so important to your body function. CoQ10 is a cellular energy booster and powerful antioxidant, and is an essential part of your body's energy process. It is found throughout your body, but the highest concentration is in the heart muscle because of the high demand the heart needs. Coenzyme Q10 is a nutrient necessary to the functioning of every cell in our bodies, but interestingly, our bodies' production of Coenzyme Q10 begin to decline around age 20-30 and steadily decreases with age, making supplementation potentially important. Since Coenzyme Q10 production occurs in the same metabolic pathway as does cholesterol, it is suspected that the increased cholesterol synthesis that occurs as we age may be responsible for the drop off in Coenzyme Q10 levels. CoQ10, also known as Ubiquinone or Ubidecarenone, is available as a supplement, and by taking it regularly you will find a significant increase in your energy, memory and overall health. Leading experts say it is extremely critical that you supplement your body’s supply of CoQ10 as you age. After 30, natural levels of the protein begin to slow down. By the time you are 50 you levels are too low for your heart to function at its best. By 70 the levels have gotten so low you actually begin to accelerate your aging. Coenzyme Q10 is a chemical found naturally in the body that contributes to the production of ATP, the body's main source of energy. CoQ10 supplements help insure maximum physical energy which can help with concentration and memory. Studies indicate this supplement may help protect against age-related memory decline, including Parkinson's disease. DMAE DMAE can be found in high concentrations in fish, and is naturally produced in the brain. It is believed to help in the production of acetylcholine, an important neurotransmitter responsible for proper brain function. The longer name for DMAE is dimethylethanolamine. This supplement is believed to help with mental energy, alertness, and concentration. This is another compound that is able to cross the blood-brain barrier to reach brain cells. Some studies have been positive that DMAE may enhance alertness and mood, and be 90 of help in alleviating symptoms of ADHD and ADD and accelerate learning, while decreasing irritability. Gingko Biloba Ginkgo Biloba has been used for thousands of years in Chinese traditional medicine. It is one of the top-selling herbs in the United States, and is one supplement that shows promise as a memory enhancer. It is commonly used in Europe for a type of dementia resulting from reduced blood flow in small vessels. Ginkgo biloba extract is an approved treatment for dementia in Germany, and it is the only nonprescription substance considered a treatment for dementia in Canada. It is said to enhance mental efficiency in elderly patients with mild to moderate memory impairment. It has also shown to improve cognitive function in patients with dementia, enhance blood flow to the brain, and improve cognitive performance in patients with Alzheimer's disease. Further it is said to enhance memory in young individuals. "A couple of meta-analyses and systematic reviews show that ginkgo biloba is helpful for dementia in about the same range as drugs being pushed very heavily to treat Alzheimer's," says Adriane Fugh-Berman, MD, an associate professor in the department of physiology and biophysics at Georgetown University School of Medicine. Fugh-Berman says ginkgo may not be able to prevent dementia, but in those who already have it the supplement has been shown to either improve symptoms or stabilize them so that they don’t get any worse. Some, but not all studies show the enhancement of alertness, mood, and mental ability in healthy people who take ginkgo, but more research needs to be done to be certain about these results. Studies as the effect of gingko Biloba are actually mixed. A study by the National Institute on Aging (NIH) involved 200 healthy adults older than 60 years of age. Gingko showed no improvement in memory or concentration. Researchers believe it may be possible that if they administered higher doses than the 120 milligrams used daily in this six-week trial the herb could be effective. Another study involving 3,000 subjects, over a longer term hopefully will produce different results. Some research does suggest that ginkgo biloba can actually be as effective for early-stage Alzheimer's disease as acetylcholinesterase inhibitor drugs - such 91 as donepezil (Aricept). Studies also indicate that it may be helpful in dilating blood vessels and decreases the stickiness of blood platelets that produce a decreased flow of blood to the brain (cerebral insufficiency). A study in The Journal of the American Medical Association in 2009 showed that, compared with placebo, 120 mg twice daily of ginkgo biloba showed no difference in cognitive decline in older adults with normal or only mild thinking impairment. Ginkgo biloba is available in tablets, capsules, teas, and fortified foods. Their seeds can be very toxic. Tea bags often contain 30 milligrams of ginkgo biloba extract, while a typical dose used in ginkgo biloba studies is 80 to 240 milligrams of a standardized extract daily by mouth in two to three divided doses. Although ginkgo biloba is generally safe it does contain blood-thinning properties. Stop using ginkgo Biloba, or use caution, before surgery or dental procedures because the risk of bleeding is greater if you are taking blood thinners like aspirin or warfarin. Also, there is the possibility that ginkgo biloba can affect your insulin or blood sugar levels, so be cautious if you have diabetes or hypoglycemia, or if you take products that affect blood sugar. Minor side effects of ginkgo biloba may include headache, nausea, or intestinal problems. Blueberry Juice If you were to exchange your cup of orange juice in the morning for a cup of blueberry juice you might just improve your memory. Blueberries are full of antioxidants, in addition to a plethora of chemicals that increase the signals to the brain that helps aid memory. The polyphenol found in blueberries also help get rid of too much glucose in the brain, which slows down memory function. Hawthorn Hawthorn is known to clean out toxins in the brain and strengthen blood vessels and tissues. It contains antioxidants that help the blood to increase the flow of oxygen and needed nutrients to the brain. Huperizine A The huperizine A supplement is an extract of the Chinese moss “huperzia serrata”. Studies have shown that hyperzine A enhances memory and learning by helping the interaction of neurotransmitters in the brain. 92 Found to fight mild age-related memory loss, including Alzheimer's disease, huperizine A is also useful in boosting short-term memory, such as when one is preparing for an exam. Omega-3 Fatty Acids Omega-3 fish oil supplements have become quite the rage lately. People are flocking to add cold-water fish, fish oil and omega 3 fatty acids to their diet in order to increase their brainpower, and lower their risk of dementia or Alzheimer’s disease. There are more thorough studies needed that compare omega-3s to placebo in order to prove the memory benefit from supplements. Various studies have shown that in addition to being good for your heart, fish oil supplements, which contain the Omega-3 fatty acids EPA and DHA, decrease the risk of age-related cognitive decline and dementia diseases. DHA is required for normal brain function in adults, and the addition of it can also help in the brain development of children, since the brain needs certain levels of DHA to function properly. If the correct levels of DHA aren’t present, the brain substitutes DPA, a different molecule, which hinders brain activity. Essential fatty acids, otherwise known as fish oils, or EPA-DHA, are well known for their antiinflammatory properties, and we must get them from food. They are necessary for the regulation of metabolism, optimal brain function, hair growth, bone health, and many other vital physiological reactions. Omega-3 and omega-6 fats are known as "essential fatty acids." Putting them into your diet, along with a proper balance of other essential vitamins and minerals, are important. The omega6 fats are best to eat less of while increasing the amount of omega-3 in your diet, although both are necessary. A lack of essential fatty acids, or an imbalance of them in your diet, can result in fatigue, dry skin and hair, broken fingernails, weakness, joint pain, mood disorders, digestion difficulties, slow healing of wounds, higher cholesterol, and elevated blood pressure. Check out your diet to make sure that you are eating some form of essential fats most days. Although the typical American diet has plenty of essential fatty acids, it is always good to evaluate your intake for best results. Omega-6 fatty acids are readily found in meats, oily salad dressings, and cooking oils that many people take in large amounts of, too frequently. Try eating smaller servings of animal protein, 93 using salad dressing with nuts or seeds instead of oil-based, and oil-free or reduced fat cooking oil-free. Some people believe that by eliminating fats in your diet you will lose weight and be healthier. That is not true. Your brain needs fat in order to survive, so it is imperative that you get enough fats in your diet. The difference is, there are good fats and bad fats. Try to have most of those fats from whole-food sources, like nuts and seeds instead of oils. Avoid fried foods. Choose less beef, chicken, ham, and pork. Eat more cold-water fish such as salmon, herring, and mackerel (farm grown and not from the open sea). The 2010 Dietary Guidelines for Americans recommends that you receive 20%30% of your daily calories come from fats. Be sure to include sources that include the essential fatty acids. Many health professionals recommend a range of 2:1 omega-6 fatty acids to omega 3-acids. Most people consume far too few omega-3s while way too many omega-6s. Consuming fried foods, food with white sugar, and foods made with trans-fats (partially hydrogenated oils) can interfere with the absorption of essential fatty acids. Products made with refined white flour are missing the nutrient-rich germs that contain essential fats. Try to limit the consumption of foods made from highly processed grains. Phosphatidyl Serine One of the more popular brain-improvement supplements today is phosphatidyl serine (PS), a major component of the outer protective layers of brain cells. Although this supplement is often advertised as helping to fight off age-related memory decline, scientists are mixed as to the truth of this statement. Preliminary studies exist, however, that indicate PS may be of help in the treatment of ADHD. PS is a healthy brain fat that is the building block in all cell membranes, and you can’t have healthy cell membranes without it. The problem comes as you age and your body naturally produces less PS, and you are not able to get as much from your diet because it is not readily available in most foods. For this reason, PS as a supplement is important, and you will see an almost immediate difference. Take for example a scientific study involving 149 patients aged 50-75; all were suffering from memory loss. Half of the patients were given a placebo, and half 94 received PS. Three weeks into the study the patients taking the PS showed a noticeable improvement in their memory and learning skills. These results were so impressive, the researchers proceeded to take the study a step further and extend the research. After 12 weeks those taking the PS had an easier time remembering telephone numbers, concentrating, finding objects and paying attention while driving. As a matter of fact, although the average chronological age was 64, the “brain age” of the participants taking PS tested out at 52 - 12 years younger than they actually were! In another study, subjects with impaired memories and who were taking PS notices a major improvement in just six weeks in 9 out of 10 of them. In at least 61 other clinical studies, and from 2,800 research papers, PS has shown to improve memory, attention, verbal fluency, and overall mental function. Rhodela/Rhodiola Rosea Stress can have a major affect on your memory, but the sub-arctic plant Rhodiola can help combat the symptoms of stress. A recent study found that subjects who took rhodiola were better able to focus and had a larger attention span. They were able to perform tasks with fewer errors than those who did not that the supplement. This plant may be effective in mood disorders, fighting depression and mental exhaustion by changing the serotonin and dopamine levels in the brain. Rosemary Rosemary is a popular spice in many cooking dishes - like stuffing and roasts. It contains antioxidants and other compounds that have been useful in many medical treatments - such as strokes, cancers and Alzheimer’s disease. It is primarily thought of as the herb to improve memory and brain function, as well as aid in concentration. Spirulina Spirulina, a type of microscopic algae that is blue-green in color, has become popular as a dietary supplement because of its high content of vitamins and minerals. It is also a valuable because it contains more protein than meat and soy combined. It includes all essential amino acids, including cysteine, lysine and methionine. 95 Spirulina can be an ideal dietary supplement for those who want or trying to follow a high protein diet. Proteins create a feeling of fullness, which means you won’t eat as much as you usually would before getting full. By following a diet rich in proteins, you will be able to get rid of the extra pounds very easily. This dietary supplement also includes a wide range of essential fatty acids (omega-3 or omega 6): AA (arachidonic acid) GLA (gamma-linolenic acid) ALA (alpha-linolenic acid) SDA (stearidonic acid) DHA (docosahexaenoic acid) EPA (eicosapentaenoic acid) LA (linoleic acid) Your body cannot process these fatty acids, so your diet remains the only source. Some of them - like DHA and EPA, are used in the treatment for depression, while others are used for the treatment of inflammation. In addition, many essential fatty acids have antioxidant properties, and are able to play an important role in the weight loss process. Spirulina is abundant in vitamins and minerals like A, B complex, C, D, E and K. This makes it a very effective supplement for anyone who suffers from a nutrient deficiency. Spirulina also contains a wide range of minerals: Boron Calcium Chloride Chromium Copper Germanium Iodine Iron Manganese Magnesium Molybdenum Phosphorus Potassium 96 Selenium Sodium Zinc Potassium seems to be the mineral in largest supply, but the other minerals are also found in adequate amounts that can be effective for treating deficiencies. Note: People suffering from phenylketonuria should not take spirulina. One of the amino acids found in this alga (phenylalanine) does not metabolize with this metabolic disorder. The amino acid will start to accumulate in the brain, and eventually lead to severe and damaging effects. This supplement could also pose a threat to people suffering from kidney or liver diseases. When it is consumed in great quantities, the high content of vitamins and minerals may lead to toxic reactions. Microcystins toxins are sometimes found in spirulina, and even though they toxins are very seldom present, if they are and the person ingests spirulina they can create deposits in the liver, which can lead to liver cancer and other liver diseases. Food for Thought 1. Are you getting enough from this book to understand which vitamins, minerals, herbs and supplements will help you achieve your optimum brain health? 2. What supplements have you found that will help you have a better memory? 3. Did this book help you at all? Please give us some feedback as to what you think. 97 Chapter 8 Resources WebMD - Fortify Fortifying Your Memory With Supplements: http://www.webmd.com/vitamins-and-supplements/lifestyle-guide-11/fortifyingyour-memory-with-supplements Memory Improvement Tips - Vitamins for Memory: http://www.memoryimprovement-tips.com/vitamins-for-memory.html Curiosity.com - Which Vitamins Can Help Improve Your Memory? http://curiosity.discovery.com/question/vitamins-help-improve-memory Memoryzine.com - 9 Vitamins & Supplements To Improve Your Memory: http://ezinearticles.com/?9-Vitamins-and-Supplements-to-Improve-YourMemory&id=44634 Reuters Health - Can vitamins help boost memory? http://www.reuters.com/article/2011/07/28/us-vitamins-memoryidUSTRE76R7LZ20110728 The Daily Green - Top 10 Sources of Vitamin C (Including 3 Foods With more than Oranges): http://www.thedailygreen.com/healthy-eating/eat-safe/topsources-vitamin-C-44102808#ixzz2044rwd65 Symptomfind.com - 7 Super vitamins that help improve your memory : http://www.google.com/search?q=Vitamins+that+help+your+memory&ie=utf8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a Livestrong.com - How to improve your memory with vitamins: http://www.livestrong.com/article/397141-how-to-improve-your-memory-withvitamins/ Livestrong.com - The importance of vitamin B1 for brain health: http://www.livestrong.com/article/481519-importance-of-vitamin-b1-for-brainhealth/ 98 Livestrong.com - Vitamins for brain health: http://www.livestrong.com/article/390470-vitamins-for-brain-health/ Livingstrong - Does it matter if vitamins are taken in the morning or at night? http://www.livestrong.com/article/536795-does-it-matter-if-vitamins-are-taken-inthe-morning-or-at-night/ Natural Health - Natural Memory Supplements: Improve Your Memory With Herbs, Foods and Minerals: http://www.naturalhomeandgarden.com/naturalhealth/natural-memory-supplements-improve-your-memory-with-herbs-foodsand-minerals.aspx#ixzz204GVrAXI Livestrong.com - Minerals to help with memory loss: http://www.livestrong.com/article/275401-minerals-to-help-with-memory-loss/ Sacred Eden - Memory Supplements: http://sacrededenblog.com/memorysupplements/ Memory - Memory improvement with vitamins, minerals and proteins : http://memory6.blogspot.com/2012/05/memory-improvement-with-vitamins.html Global Healing Center - Foods, Vitamins and Herbs that Boost Your Brain Power: http://www.globalhealingcenter.com/natural-health/foods-that-boost-your-brainpower/ MedicineNet.com - Vitamins and Minerals To Boost Brain Power: http://www.medicinenet.com/script/main/art.asp?articlekey=55784&page=2 Keeping Your Brain Healthy - Brain FX - Which vitamins are good for your brain?: http://www.brain-fx.com/53_vitamins_minerals_supplements/ Rock Creek Free Press - Miracle Mineral Protects Your Brain: http://rockcreekfreepress.tumblr.com/post/409440581/lithium eHow.com - The Best Vitamins for the Brain: http://www.ehow.com/about_5367347_vitamins-brain.html#ixzz20oQXA3at Dummies.com - Boron: A Trace Mineral Necessary for Good Health: http://www.dummies.com/how-to/content/boron-a-trace-mineral-necessary-forgood-health.html LivingStrong.com - The best minerals for good nerve function: http://www.livestrong.com/article/505203-the-best-minerals-for-good-nervefunction/#ixzz20oX0P5o2 99 FITDAY - Healthy Living 101 - Everything You Need to Know About Iron: http://www.fitday.com/fitness-articles/nutrition/healthy-living-101-everything-youneed-to-know-about-iron.html Annie’s Remedies, Essential Oils and Herbs http://www.anniesremedy.com/chart_remedy.php?tag=memory eHow.com - How to Use herbs to Increase memory: http://www.ehow.com/how_2033013_use-herbs-increase.html ListVerse - Top 10 Vitamin Deficiencies: http://listverse.com/2012/03/16/top-10vitamin-deficiencies/ HGTV Summer - What are B Vitamins? http://www.freefitnesstips.co.uk/what-areb-vitamins.html MedicineNet.com - Lithium: http://www.medicinenet.com/lithium/article.htm Rock Creek Free Press - Miracle Mineral Protects Your Brain: http://rockcreekfreepress.tumblr.com/post/409440581/lithium MedVantic Solutions: Adaptogenic Herbs: Nature's Solution To Stress http://www.chiro.org/nutrition/FULL/Adaptogenic_Herbs.shtml 100