Study programme
:
DENTISTRY
Course name
:
PATHOLOGICAL PHYSIOLOGY 2
Abbreviation
:
PFY/ZAA12
Schedule
:
15 hours of lectures
45 hours of exercises
Course distribution :
3rd year, 5th semester
Number of Credits
:
8
Course Form
:
Lectures, exercises
Lectures:
Teachers :
prof. MUDr. Martin Petřek, CSc.
MUDr. Dagmar Riegrová, CSc.
Study:
Continuous
Date
1 14. 9. 2015
Subjects
Selected problems of GIT .
Pathophysiology of oral cavity. Dysphagia. Pathophysiology
of oesophagus. Ulcerative disease.
Pathophysiology of digestive system.
Motility disorders of small and large intestine, diarrhea,
constipation.
2 28. 9. 2015 Holiday.
Selected problems of liver and bile ducts pathophysiology.
Liver failure. Hepatic cirrhosis. Ascites.
3 12. 10. 2015 Pathogenetic aspects of modern diabetology.
Diabetes types, genetic principle of DM predisposition. Autoimmune
features of DM I. type. Trigger mechanisms . Principles of insulin
resistance in DM II. type. Actual DM classifica- tion and diagnostic
possibilities.
4 26. 10. 2015 Selected problems of kidney pathophysiology.
Acute and chronic kidney failure.
5 9. 11. 2015 Selected problems of endocrine system pathophysiology.
Pathogenesis of endocrine gland diseases, modern knowledge of their
role in homeostasis, defense mechanisms including immune reactions.
6 23. 11. 2015 Selected problems of nervous system disorders.
Overview of latest knowledge about pathogenesis of the most
frequent central and peripheral nervous system diseases. Paralysis.
Extrapyramidal system.
1
Duratio
n (hrs)
2
2
2
2
2
2
7 7. 12. 2015
Consciousness and cognitive function disorders.
Memory disorders. Speech function disorders.
Disturbances of calcium and phosphorus balance. Bone
pathophysiology.
Osteoporosis, osteomalacia, rachitis, osteodys- trophia.
2
8 21. 12. 2015 Holliday A substitute term according to students´ choice
- 1. 1. 2015 Selected problems of mouth cavity and dentition pathophysiology.
1
Mouth cavity changes in nutrition disturbances, inflammatory
processes, general diseases, tumours. Salivary gland diseases,
lymphadenopathy. Pathophysiological principle of tooth decay and
parodontopathy.
The lectures are held in the No. 2.520 room at New Building on Mondays, from 8.00 a.m. to
8.45 a.m.
Exercises:
prof. MUDr. Martin Petřek, CSc.
MUDr. Dagmar Riegrová, CSc
Other members of the Department
Study :
Week
from-to
1 14. 9. 2015
2 21. 9. 2015
3 28. 9. 2015
4 5. 10. 2015
5 12. 10. 2015
6 19. 10. 2015
7 26. 10. 2015
2
Continuous
Subject
Stress and general adaptation syndrome.
Stressors, eustress, disstres. Stress phases. Chronic stress.
Psychosomatic diseases.
Pathophysiology of GIT.
Pathophysiology of salivary glands. Chosen diseases of
oesophagus, ventricle, intestine.
Holiday.
Nutrition disturbances.
Nutritive and energetic balance, protein and nitrogen
balance. Obesity. Malnutrition. Parenteric nutrition.
Malassimilation syndromes.
Maldigestion,,malabsoption.
Pathophysiology of lipid metabolism. Atherosclerosis.
Pathophysiology of purine metabolism. Gout.
Disturbances of vitamins uptake. Hyper, hypovitaminosis.
Pathophysiology of liver function. Jaundice – causes,
types, consequences.
Disturbances of exocrine pancreas.
Pathophysiology of saccharide metabolism.
Diabetes mellitus.
Hypo, hyperglycaemia. Acute and chronic complications.
Analysis of clinical cases.
Test No. 1. Content of exercises 1-5, lectures 1-2
Disturbances of ABB.
Acid-base quantities, parameters, classification,
compensation, correction, therapy principles,
complications.
Duration Teacher
(hrs)
2
Riegrová
4
Riegrová
2
Riegrová
4
Riegrová
2
Riegrová
4
Riegrová
2
Riegrová
8 2. 11. 2015
9 9. 11. 2015
10 16. 11. 2015
11 23. 11. 2015
12 30. 11. 2015
13 7. 12. 2015
14 14. 12. 2015
15 21. 12. 2015
– 1. 1. 2015
Water and ion management.
Disturbances of water and osmotic balance. .
Principles and risks of infusion therapy.
Pathophysiology of kidney functions.
Proteinuria. Haematuria. Nephrotic syn. Pathogenesis of
kidney diseases for extrarenal causes. Urolithiasis.
Pathophysiology of endocrine system.
Disturbances of adrenal cortex, parathyroid gland funct.
Disturbances of menstrual cycle. Hypogonadism.
Central and peripheral nervous system disorders I
Disability of pyramidal pathway. Disturbances of
extrapyramidal system. Ataxy. Walking disorders.
Video: Parkinsonism.
Test No. 2. Content of exercise 6-9, lectures 3-4.
Central and peripheral nervous system disorders II.
Brain perfusion disorders, vascular epizode, brain oedema.
Epilepsy. Comas. Alzheimer disease.
Video: Epilepsy. Narcolepsy.
4
Riegrová
2
Riegrová
4
Riegrová
2
Riegrová
4
Riegrová
Pathophysiology of selected rheumatic diseases and
systemic connective tissue diseases.
Ethiopathogenesis, manifestation symptoms, therapy
principles.
MODS pathophysiology. Compensatory mechanisms,
symptoms, consequences, complications.
Test No 3. Content of exercises 10-13 and lectures 5-7
Holiday
Final test. Substitute exercise. Credit.
2
Riegrová
4
Riegrová
3
Riegrová
The exercises are held in the No. 2.520 room at New Building on Mondays, from 9.00 a.m.,
to 11. 15 a.m.
Completed by:
Requirements:
3
Credit. Examination.
1) Successful attendance of the exercises is expected (one
absence excused without necessity to supply it).
Letter of apology is necessary in the case of another
absence(s). No more than three absences can be
excused by the Department. The students may
substitute their absence(s) in week 15 of the semester.
2) Sufficient knowledge of anatomy, biochemistry, and
physiology as well as adequate activity and
interaction in discussions during the exercises is
required. Passivity can be assessed by a teacher as an
absence of the student in the exercise.
3) Achieving of at least 70% mean value of the
maximum score attainable in the three tests.
4) In the case of mean scoring less than 70%, the
students will undergo a final credit test in the week 15
of the semester. The limit is 70% of the maximum
score attainable in this test.
5) In the case of scoring between 55%-69% of the
maximum in the final credit test, the student may
undergo an oral interview in a date offered by the
Department.
6) In the case of scoring less than 55% of the maximum
in the final credit test, or in the case of falling in the
oral interview, there is possibility for the student to
ask, in a written form, the head of the Department for
an extra re-examination.
Literature:
1. Guyton A. C.: Textbook of Medical Physiology .
11 t h Edition. Saunders, 2005.
2. Hulín I.: Pathophysiol ogy . Principles of Diseases .
2 n d Ed. SAV Bratislava, 1998 .
3. McCance K. L., Huether S. E.: Pathophysiology .
3 r d Edition. Mosby, 1998
4. Braunwald E et al : Harrisons´s Principles of Internal
Medicine. 15th Edition. McGraw-Hill, 2001.
5. Weatherall, Ledingham, Warrel: Oxford Textbook of
Medicine, Vol. 1, 2. 2nd Edition. 1988.
6. www. mefanet. cz; http://portal. med. muni. cz/;
http://portal. lf1. cuni. cz/
4